AU1592597A - Gas bubble suspensions and their application as an ultrasound contrast medium - Google Patents

Gas bubble suspensions and their application as an ultrasound contrast medium

Info

Publication number
AU1592597A
AU1592597A AU15925/97A AU1592597A AU1592597A AU 1592597 A AU1592597 A AU 1592597A AU 15925/97 A AU15925/97 A AU 15925/97A AU 1592597 A AU1592597 A AU 1592597A AU 1592597 A AU1592597 A AU 1592597A
Authority
AU
Australia
Prior art keywords
application
contrast medium
gas bubble
ultrasound contrast
bubble suspensions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU15925/97A
Inventor
Martina Bergmann
Thomas Fritzsch
Dieter Heldmann
Violetta Sudmann
Werner Weitschies
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of AU1592597A publication Critical patent/AU1592597A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/04—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent
    • C08J9/12—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent
    • C08J9/14—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent organic
    • C08J9/143—Halogen containing compounds
    • C08J9/147—Halogen containing compounds containing carbon and halogen atoms only
    • C08J9/148—Halogen containing compounds containing carbon and halogen atoms only perfluorinated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
    • A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
    • A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/04—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent
    • C08J9/12—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent
    • C08J9/14—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof using blowing gases generated by a previously added blowing agent by a physical blowing agent organic
    • C08J9/143—Halogen containing compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2300/00—Characterised by the use of unspecified polymers
AU15925/97A 1996-01-18 1997-01-16 Gas bubble suspensions and their application as an ultrasound contrast medium Abandoned AU1592597A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19602930A DE19602930A1 (en) 1996-01-18 1996-01-18 Porous matrices made of low molecular weight substances for the generation of stable gas bubble suspensions, their use as ultrasound contrast agents and processes for their production
DE19602930 1996-01-18
PCT/EP1997/000208 WO1997026016A2 (en) 1996-01-18 1997-01-16 Gas bubble suspensions and their application as an ultrasound contrast medium

Publications (1)

Publication Number Publication Date
AU1592597A true AU1592597A (en) 1997-08-11

Family

ID=7783852

Family Applications (1)

Application Number Title Priority Date Filing Date
AU15925/97A Abandoned AU1592597A (en) 1996-01-18 1997-01-16 Gas bubble suspensions and their application as an ultrasound contrast medium

Country Status (8)

Country Link
EP (1) EP0874644A2 (en)
JP (1) JP2000504317A (en)
AU (1) AU1592597A (en)
CA (1) CA2243174A1 (en)
DE (1) DE19602930A1 (en)
NO (1) NO983332L (en)
WO (1) WO1997026016A2 (en)
ZA (1) ZA97414B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2631014C (en) * 2005-11-28 2015-04-28 Vernon D. Rowe Compositions useful for reducing nephrotoxicity and methods of use thereof
JP5196896B2 (en) * 2007-07-13 2013-05-15 花王株式会社 Method for producing fine bubble precursor
JP2010005512A (en) * 2008-06-25 2010-01-14 Kao Corp Microbubble precursor composition
KR101927614B1 (en) 2017-03-30 2018-12-10 숭실대학교산학협력단 Preparing method of contrast agent with stable oxygen-nanobubble or ultrasound imaging
JP7211699B2 (en) * 2017-09-11 2023-01-24 バイエル ファーマ アクチエンゲゼルシャフト Ultrasound contrast agent

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3141641A1 (en) * 1981-10-16 1983-04-28 Schering Ag, 1000 Berlin Und 4619 Bergkamen ULTRASONIC CONTRAST AGENTS AND THEIR PRODUCTION
DE3313947A1 (en) * 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen MICROPARTICLES AND GAS BUBBLES CONTAINING ULTRASONIC CONTRASTING AGENTS
DE3313946A1 (en) * 1983-04-15 1984-10-18 Schering AG, 1000 Berlin und 4709 Bergkamen MICROPARTICLES AND GAS BUBBLES CONTAINING ULTRASONIC CONTRASTING AGENTS
DE3834705A1 (en) * 1988-10-07 1990-04-12 Schering Ag ULTRASONIC CONTRASTING AGENTS FROM GAS BUBBLES AND MICROPARTICLES CONTAINING FATTY ACID
DE3709851A1 (en) * 1987-03-24 1988-10-06 Silica Gel Gmbh Adsorptions Te NMR DIAGNOSTIC LIQUID COMPOSITIONS
US5445813A (en) * 1992-11-02 1995-08-29 Bracco International B.V. Stable microbubble suspensions as enhancement agents for ultrasound echography
US5147631A (en) * 1991-04-30 1992-09-15 Du Pont Merck Pharmaceutical Company Porous inorganic ultrasound contrast agents
JP3319754B2 (en) * 1991-06-03 2002-09-03 ニユコメド・イメージング・アクシエセルカペト Improvements in or on contrast agents
ATE151993T1 (en) * 1991-07-05 1997-05-15 Nycomed Imaging As IMPROVEMENTS TO CONTRAST AGENTS
AU2317592A (en) * 1991-07-05 1993-02-11 University Of Rochester Ultrasmall non-aggregated porous particles entrapping gas-bubbles
HU218018B (en) * 1991-09-17 2000-05-28 Sonus Pharmaceuticals Inc. Gaseous ultrasound contrast media and method for selecting gases for use as ultrasound contrast media
GB9200388D0 (en) * 1992-01-09 1992-02-26 Nycomed As Improvements in or relating to contrast agents
IL104084A (en) * 1992-01-24 1996-09-12 Bracco Int Bv Long-lasting aqueous suspensions of pressure-resistant gas-filled microvesicles their preparation and contrast agents consisting of them
US5798091A (en) * 1993-07-30 1998-08-25 Alliance Pharmaceutical Corp. Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement
DK0711179T3 (en) * 1993-07-30 2005-02-14 Imcor Pharmaceutical Co Stabilized ultrasound microbubble compositions
KR100295173B1 (en) * 1993-12-15 2001-09-17 엔. 토모브 Gas Mixtures Useful as Ultrasonic Contrast Media
GB9402867D0 (en) * 1994-02-15 1994-04-06 Nycomed Imaging As Improvements in or relating to contrast agents
DE4406474A1 (en) * 1994-02-23 1995-08-24 Schering Ag Gas-containing microparticles, agents containing them, their use in ultrasound diagnostics, and methods for producing the particles and agents

Also Published As

Publication number Publication date
JP2000504317A (en) 2000-04-11
NO983332D0 (en) 1998-07-17
DE19602930A1 (en) 1997-07-24
WO1997026016A2 (en) 1997-07-24
ZA97414B (en) 1997-07-17
CA2243174A1 (en) 1997-07-24
NO983332L (en) 1998-07-17
EP0874644A2 (en) 1998-11-04
WO1997026016A3 (en) 1997-10-23

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