NO982906L - Heterosyklylkondenserte benzoylguanidiner, deres fremstilling og anvendelse som inhibitorer for den cellulµre Na+/H+-antiporter - Google Patents
Heterosyklylkondenserte benzoylguanidiner, deres fremstilling og anvendelse som inhibitorer for den cellulµre Na+/H+-antiporterInfo
- Publication number
- NO982906L NO982906L NO982906A NO982906A NO982906L NO 982906 L NO982906 L NO 982906L NO 982906 A NO982906 A NO 982906A NO 982906 A NO982906 A NO 982906A NO 982906 L NO982906 L NO 982906L
- Authority
- NO
- Norway
- Prior art keywords
- stands
- antiporter
- inhibitors
- cellular
- nha
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/66—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19548708A DE19548708A1 (de) | 1995-12-23 | 1995-12-23 | Cyclische Sulfone |
PCT/EP1996/005645 WO1997023476A1 (de) | 1995-12-23 | 1996-12-16 | HETEROCYCLYLKONDENSIERTE BENZOYLGUANIDINE, DEREN HERSTELLUNG UND DEREN VERWENDUNG ALS INHIBITOREN DES ZELLULÄREN Na+/H+-ANTIPORTERS |
Publications (2)
Publication Number | Publication Date |
---|---|
NO982906D0 NO982906D0 (no) | 1998-06-22 |
NO982906L true NO982906L (no) | 1998-06-22 |
Family
ID=7781400
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO982906A NO982906L (no) | 1995-12-23 | 1998-06-22 | Heterosyklylkondenserte benzoylguanidiner, deres fremstilling og anvendelse som inhibitorer for den cellulµre Na+/H+-antiporter |
Country Status (18)
Country | Link |
---|---|
US (1) | US6028069A (de) |
EP (1) | EP0873335A1 (de) |
JP (1) | JP2000502663A (de) |
KR (1) | KR19990076675A (de) |
AR (1) | AR004402A1 (de) |
AU (1) | AU710048B2 (de) |
BR (1) | BR9612200A (de) |
CA (1) | CA2241143A1 (de) |
CZ (1) | CZ199798A3 (de) |
DE (1) | DE19548708A1 (de) |
HU (1) | HUP9802920A3 (de) |
NO (1) | NO982906L (de) |
PL (1) | PL327186A1 (de) |
RU (1) | RU2161616C2 (de) |
SK (1) | SK81598A3 (de) |
TW (1) | TW381091B (de) |
WO (1) | WO1997023476A1 (de) |
ZA (1) | ZA9610724B (de) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4328352A1 (de) * | 1993-08-24 | 1995-03-02 | Hoechst Ag | Substituierte N,N'-Di-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
WO1998055475A1 (en) * | 1997-06-02 | 1998-12-10 | Fujisawa Pharmaceutical Co., Ltd. | Guanidine deriviatives as inhibitors of na+/h+ exchange in cells |
US6730697B2 (en) * | 2002-02-07 | 2004-05-04 | Aventis Pharma Deutschland Gmbh | Dihydrothiaphenanthrenecarbonylguanidines: composition, process of making, and use as medicament or diagnostic aid |
TW200614995A (en) * | 2004-11-10 | 2006-05-16 | Nicholas Piramal India Ltd | Tricyclic guanidine derivatives as sodium-proton exchange inhibitors |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3929582A1 (de) * | 1989-09-06 | 1991-03-07 | Hoechst Ag | Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament |
DK0589336T3 (da) * | 1992-09-22 | 1997-06-16 | Hoechst Ag | Benzylguanidiner, fremgangsmåde til deres fremstilling samt deres anvendelse som antiarytmetika |
ES2152938T3 (es) * | 1992-09-28 | 2001-02-16 | Hoechst Ag | 1(2h)-isoquinolinas sustituidas antiarritmicas y cardioprotectoras, procedimiento para su produccion, medicamento que las contiene y su uso para la produccion de un medicamento para combatir fallos cardiacos. |
US5514801A (en) * | 1992-12-29 | 1996-05-07 | Monsanto Company | Cyclic sulfone containing retroviral protease inhibitors |
CA2121391A1 (en) * | 1993-04-28 | 1994-10-29 | Atsuyuki Kojima | Indoloylguanidine derivatives |
DE4317076A1 (de) * | 1993-05-21 | 1994-11-24 | Bayer Ag | Benzthiophencarbonsäureamid-S-oxide |
US5607898A (en) * | 1993-08-02 | 1997-03-04 | Idemitsu Kosan Company, Ltd. | Pyrazole derivatives |
EP0639573A1 (de) * | 1993-08-03 | 1995-02-22 | Hoechst Aktiengesellschaft | Benzokondensierte 5-Ringheterocyclen, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament, ihre Verwendung als Diagnostikum, sowie sie enthaltendes Medikament |
US5627194A (en) * | 1993-11-17 | 1997-05-06 | Allelix Biopharmaceuticals Inc. | Anti-viral guanidino-substituted compounds |
DE4344550A1 (de) * | 1993-12-24 | 1995-06-29 | Hoechst Ag | Substituierte 1-Oxo-1,2-dihydro-isochinolinoyl- und 1,1-Dioxo-2H-1,2-benzothiazinoylguanidine, Verfahrenzu ihrer Herstellung, ihre Verwendung als Medikamentt oder Diagnostikum sowie sie enthaltendes Medikamen |
DE4412334A1 (de) * | 1994-04-11 | 1995-10-19 | Hoechst Ag | Substituierte N-Heteroaroylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
AU683552B2 (en) * | 1994-04-11 | 1997-11-13 | Chugai Seiyaku Kabushiki Kaisha | 4,6-DI-t-butyl-2,3-dihydrobenzothiophene derivative |
US5863936A (en) * | 1995-04-18 | 1999-01-26 | Geron Corporation | Telomerase inhibitors |
US5821250A (en) * | 1996-02-01 | 1998-10-13 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
FR2762598A1 (fr) * | 1997-04-25 | 1998-10-30 | Adir | Nouveaux composes heterocycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennnent |
-
1995
- 1995-12-23 DE DE19548708A patent/DE19548708A1/de not_active Withdrawn
-
1996
- 1996-10-20 AR ARP960105800A patent/AR004402A1/es unknown
- 1996-11-19 TW TW085114208A patent/TW381091B/zh active
- 1996-12-16 AU AU11960/97A patent/AU710048B2/en not_active Ceased
- 1996-12-16 CZ CZ981997A patent/CZ199798A3/cs unknown
- 1996-12-16 HU HU9802920A patent/HUP9802920A3/hu unknown
- 1996-12-16 WO PCT/EP1996/005645 patent/WO1997023476A1/de not_active Application Discontinuation
- 1996-12-16 US US09/091,652 patent/US6028069A/en not_active Expired - Fee Related
- 1996-12-16 JP JP9523281A patent/JP2000502663A/ja active Pending
- 1996-12-16 RU RU98114077/04A patent/RU2161616C2/ru active
- 1996-12-16 KR KR1019980704787A patent/KR19990076675A/ko not_active Application Discontinuation
- 1996-12-16 PL PL96327186A patent/PL327186A1/xx unknown
- 1996-12-16 EP EP96943131A patent/EP0873335A1/de not_active Withdrawn
- 1996-12-16 CA CA002241143A patent/CA2241143A1/en not_active Abandoned
- 1996-12-16 BR BR9612200A patent/BR9612200A/pt not_active Application Discontinuation
- 1996-12-16 SK SK815-98A patent/SK81598A3/sk unknown
- 1996-12-19 ZA ZA9610724A patent/ZA9610724B/xx unknown
-
1998
- 1998-06-22 NO NO982906A patent/NO982906L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
TW381091B (en) | 2000-02-01 |
KR19990076675A (ko) | 1999-10-15 |
NO982906D0 (no) | 1998-06-22 |
HUP9802920A2 (hu) | 2000-05-28 |
CA2241143A1 (en) | 1997-07-03 |
SK81598A3 (en) | 1999-01-11 |
JP2000502663A (ja) | 2000-03-07 |
AU1196097A (en) | 1997-07-17 |
US6028069A (en) | 2000-02-22 |
BR9612200A (pt) | 1999-07-13 |
ZA9610724B (en) | 1997-06-26 |
WO1997023476A1 (de) | 1997-07-03 |
DE19548708A1 (de) | 1997-06-26 |
CZ199798A3 (cs) | 1998-10-14 |
PL327186A1 (en) | 1998-11-23 |
RU2161616C2 (ru) | 2001-01-10 |
HUP9802920A3 (en) | 2000-12-28 |
AR004402A1 (es) | 1998-11-04 |
MX9804972A (es) | 1998-09-30 |
AU710048B2 (en) | 1999-09-09 |
EP0873335A1 (de) | 1998-10-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC2A | Withdrawal, rejection or dismissal of laid open patent application |