NO980094L - Nye farnesyl-transferase-inhibitorer, deres fremstilling og farmasöytiske preparater inneholdende disse - Google Patents

Nye farnesyl-transferase-inhibitorer, deres fremstilling og farmasöytiske preparater inneholdende disse

Info

Publication number
NO980094L
NO980094L NO980094A NO980094A NO980094L NO 980094 L NO980094 L NO 980094L NO 980094 A NO980094 A NO 980094A NO 980094 A NO980094 A NO 980094A NO 980094 L NO980094 L NO 980094L
Authority
NO
Norway
Prior art keywords
preparation
pharmaceutical preparations
preparations containing
transferase inhibitors
farnesyl transferase
Prior art date
Application number
NO980094A
Other languages
English (en)
Other versions
NO980094D0 (no
NO309565B1 (no
Inventor
Alain Commercon
Alain Lebrun
Patrick Mailliet
Jean-Francois Peyronel
Fabienne Sounigo
Alain Truchon
Martine Zucco
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of NO980094D0 publication Critical patent/NO980094D0/no
Publication of NO980094L publication Critical patent/NO980094L/no
Publication of NO309565B1 publication Critical patent/NO309565B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/72—4,7-Endo-alkylene-iso-indoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/572—Five-membered rings
    • C07F9/5728—Five-membered rings condensed with carbocyclic rings or carbocyclic ring systems
NO980094A 1995-07-10 1998-01-09 Nye farnesyl-transferase-inhibitorer, deres fremstilling og farmasöytiske preparater inneholdende disse NO309565B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9508296A FR2736641B1 (fr) 1995-07-10 1995-07-10 Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR1996/001062 WO1997003050A1 (fr) 1995-07-10 1996-07-08 DERIVES DE 4,9-ETHANO-BANZO(f)ISOINDOLE COMME INHIBITEURS DE FARNESYL TRANSFERASE

Publications (3)

Publication Number Publication Date
NO980094D0 NO980094D0 (no) 1998-01-09
NO980094L true NO980094L (no) 1998-02-17
NO309565B1 NO309565B1 (no) 2001-02-19

Family

ID=9480830

Family Applications (1)

Application Number Title Priority Date Filing Date
NO980094A NO309565B1 (no) 1995-07-10 1998-01-09 Nye farnesyl-transferase-inhibitorer, deres fremstilling og farmasöytiske preparater inneholdende disse

Country Status (32)

Country Link
US (1) US5936097A (no)
EP (1) EP0839133B1 (no)
JP (1) JPH11511123A (no)
KR (1) KR19990028856A (no)
CN (1) CN1096448C (no)
AR (1) AR003143A1 (no)
AT (1) ATE185341T1 (no)
AU (1) AU712194B2 (no)
BR (1) BR9609440A (no)
CA (1) CA2224414A1 (no)
CO (1) CO4700457A1 (no)
CZ (1) CZ291620B6 (no)
DE (1) DE69604588T2 (no)
DK (1) DK0839133T3 (no)
EA (1) EA000797B1 (no)
ES (1) ES2139373T3 (no)
FR (1) FR2736641B1 (no)
GR (1) GR3031409T3 (no)
IL (1) IL122812A (no)
MA (1) MA23929A1 (no)
MX (1) MX9800262A (no)
MY (1) MY114792A (no)
NO (1) NO309565B1 (no)
NZ (1) NZ313211A (no)
PE (1) PE11898A1 (no)
PL (1) PL324430A1 (no)
SK (1) SK282250B6 (no)
TN (1) TNSN96098A1 (no)
TW (1) TW438792B (no)
UY (1) UY24276A1 (no)
WO (1) WO1997003050A1 (no)
ZA (1) ZA965868B (no)

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US6124465A (en) * 1997-11-25 2000-09-26 Rhone-Poulenc S.A. Farnesyl transferase inhibitors, their preparation, the pharmaceutical compositions which contain them and their use in the preparation of medicaments
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FR2787327B1 (fr) * 1998-12-21 2003-01-17 Aventis Pharma Sa Compositions contenant des inhibiteurs de farnesyle transferase
FR2796641B1 (fr) 1999-07-22 2001-09-21 Aventis Pharma Sa Nouveau procede de preparation de composes benzoperhydroisoindole
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KR102072631B1 (ko) 2010-08-17 2020-02-03 시르나 쎄러퓨틱스 인코퍼레이티드 짧은 간섭 핵산 （ｓｉＮＡ）을 사용한 Ｂ형 간염 바이러스 （ＨＢＶ） 유전자 발현의 ＲＮＡ 간섭 매개 억제
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US20140046059A1 (en) 2011-04-21 2014-02-13 Piramal Enterprises Limited Process for the preparation of morpholino sulfonyl indole derivatives
US9023865B2 (en) 2011-10-27 2015-05-05 Merck Sharp & Dohme Corp. Compounds that are ERK inhibitors
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US20150299696A1 (en) 2012-05-02 2015-10-22 Sirna Therapeutics, Inc. SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
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US10000483B2 (en) 2012-10-19 2018-06-19 Dana-Farber Cancer Institute, Inc. Bone marrow on X chromosome kinase (BMX) inhibitors and uses thereof
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PT3277842T (pt) 2015-08-17 2019-09-05 Kura Oncology Inc Métodos de tratamento de doentes com cancro usando inibidores da farnesiltransferase
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US10851164B2 (en) 2017-04-13 2020-12-01 Aduro Biotech Holdings, Europe B.V. Anti-SIRPα antibodies
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TW202108170A (zh) 2019-03-15 2021-03-01 美商庫拉腫瘤技術股份有限公司 以法呢基轉移酶(farnesyltransferase)抑制劑治療癌症患者之方法
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FR2492372A1 (fr) * 1980-10-21 1982-04-23 Cird Dihydroxy-1,8 anthrones-9 substituees en position 10 et leur utilisation en medecine humaine ou veterinaire et en cosmetique
JP3597863B2 (ja) * 1993-11-05 2004-12-08 ワーナー−ランバート・コンパニー タンパク質：ファルネシルトランスフェラーゼの置換されたジ‐およびトリペプチド阻害剤

Also Published As

Publication number Publication date
SK282250B6 (sk) 2001-12-03
AU712194B2 (en) 1999-10-28
PE11898A1 (es) 1998-03-15
ATE185341T1 (de) 1999-10-15
DK0839133T3 (da) 2000-04-17
TNSN96098A1 (fr) 2005-03-15
US5936097A (en) 1999-08-10
CA2224414A1 (fr) 1997-01-30
MY114792A (en) 2003-01-31
GR3031409T3 (en) 2000-01-31
NZ313211A (en) 1999-11-29
JPH11511123A (ja) 1999-09-28
CO4700457A1 (es) 1998-12-29
TW438792B (en) 2001-06-07
SK2698A3 (en) 1998-07-08
WO1997003050A1 (fr) 1997-01-30
BR9609440A (pt) 1999-06-29
NO980094D0 (no) 1998-01-09
MA23929A1 (fr) 1997-04-01
IL122812A (en) 2001-04-30
CN1190389A (zh) 1998-08-12
CZ291620B6 (cs) 2003-04-16
CN1096448C (zh) 2002-12-18
KR19990028856A (ko) 1999-04-15
EP0839133B1 (fr) 1999-10-06
FR2736641B1 (fr) 1997-08-22
IL122812A0 (en) 1998-08-16
ES2139373T3 (es) 2000-02-01
PL324430A1 (en) 1998-05-25
EA000797B1 (ru) 2000-04-24
CZ5498A3 (cs) 1998-04-15
FR2736641A1 (fr) 1997-01-17
DE69604588D1 (en) 1999-11-11
DE69604588T2 (de) 2000-05-18
UY24276A1 (es) 2001-10-25
EP0839133A1 (fr) 1998-05-06
ZA965868B (en) 1997-01-29
EA199800118A1 (ru) 1998-08-27
AU6522496A (en) 1997-02-10
MX9800262A (es) 1998-04-30
AR003143A1 (es) 1998-07-08
NO309565B1 (no) 2001-02-19

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