NO972868L - Oligonukleotid-dendrimer konjugater - Google Patents
Oligonukleotid-dendrimer konjugaterInfo
- Publication number
- NO972868L NO972868L NO972868A NO972868A NO972868L NO 972868 L NO972868 L NO 972868L NO 972868 A NO972868 A NO 972868A NO 972868 A NO972868 A NO 972868A NO 972868 L NO972868 L NO 972868L
- Authority
- NO
- Norway
- Prior art keywords
- dendrimer
- oligonucleotide
- natural
- modified
- nucleic acid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Saccharide Compounds (AREA)
Abstract
Oligonukleotid-dendrimer konjugater, der dendrimeren er et enverdig residie av en dendrimer av første til tiende generasjon og oligonukleotidet er en naturlig, modifisert eller syntetisk sekvens som består av naturlige, modifiserte eller syntetiske deoksynukleosider eller peptidnukleinsyrebyggeblokker som er bundet via intemukleotidbroer og som omfatter en region som er komplementær, fortrinnsvis fullstendig komplementær, til en målnukleinsyre (mål-RNA eller mål-DNA), der dendrimeren er bundet til en intemukleotidbro, en nukleinsyrebase eller en sukker av nukleotidet, og saltene av disse.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH385494 | 1994-12-21 | ||
CH4795 | 1995-01-09 | ||
PCT/EP1995/004933 WO1996019240A1 (en) | 1994-12-21 | 1995-12-13 | Oligonucleotide-dendrimer conjugates |
Publications (2)
Publication Number | Publication Date |
---|---|
NO972868D0 NO972868D0 (no) | 1997-06-20 |
NO972868L true NO972868L (no) | 1997-08-19 |
Family
ID=25683356
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO972868A NO972868L (no) | 1994-12-21 | 1997-06-20 | Oligonukleotid-dendrimer konjugater |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0790837A1 (no) |
JP (1) | JPH10510822A (no) |
AU (1) | AU4344696A (no) |
CA (1) | CA2206915A1 (no) |
FI (1) | FI972548A (no) |
HU (1) | HUT77521A (no) |
IL (1) | IL116456A0 (no) |
NO (1) | NO972868L (no) |
WO (1) | WO1996019240A1 (no) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5563255A (en) * | 1994-05-31 | 1996-10-08 | Isis Pharmaceuticals, Inc. | Antisense oligonucleotide modulation of raf gene expression |
US5744460A (en) * | 1996-03-07 | 1998-04-28 | Novartis Corporation | Combination for treatment of proliferative diseases |
IL133087A0 (en) * | 1997-05-28 | 2001-03-19 | Nielsen Peter E | Conjugated peptide nucleic acids having enhanced cellular uptake |
GB9718129D0 (en) | 1997-08-27 | 1997-10-29 | Isis Innovation | Branched structures |
US6287765B1 (en) * | 1998-05-20 | 2001-09-11 | Molecular Machines, Inc. | Methods for detecting and identifying single molecules |
FR2906532B1 (fr) | 2006-09-28 | 2008-12-12 | Biomerieux Sa | Nouvel oligonucleotide marque |
FR2933410B1 (fr) | 2008-07-04 | 2010-08-20 | Biomerieux Sa | Nouvelle sonde de detection |
TW202043256A (zh) | 2019-01-10 | 2020-12-01 | 美商健生生物科技公司 | 前列腺新抗原及其用途 |
AU2020385683A1 (en) | 2019-11-18 | 2022-06-30 | Janssen Biotech, Inc. | Vaccines based on mutant CALR and JAK2 and their uses |
CN112898580B (zh) * | 2019-12-03 | 2022-11-08 | 安序源生物科技(深圳)有限公司 | 测序试剂 |
CN112898575B (zh) * | 2019-12-03 | 2022-10-21 | 深圳清华大学研究院 | 树杈状大分子修饰的核苷酸的制备方法 |
EP4175664A2 (en) | 2020-07-06 | 2023-05-10 | Janssen Biotech, Inc. | Prostate neoantigens and their uses |
US20230035403A1 (en) | 2020-07-06 | 2023-02-02 | Janssen Biotech, Inc. | Method For Determining Responsiveness To Prostate Cancer Treatment |
US20230024133A1 (en) | 2020-07-06 | 2023-01-26 | Janssen Biotech, Inc. | Prostate Neoantigens And Their Uses |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL83567A (en) * | 1986-08-18 | 1992-02-16 | Dow Chemical Co | Starburst conjugates with a carried material,such as an agricultural or pharmaceutical material |
IL107715A0 (en) * | 1992-11-25 | 1994-02-27 | Baxter Int | Water soluble non-immunogenic polyamide cross-linking agents |
AU681735C (en) * | 1993-07-14 | 2002-02-21 | Regents Of The University Of California, The | Self-assembling polynucleotide delivery system comprising dendrimer polycations |
ATE277640T1 (de) * | 1994-03-07 | 2004-10-15 | Dow Chemical Co | Bioaktive und/oder gezielte dendrimere-konjugate enthaltend genetisches material |
IT1270994B (it) * | 1994-03-18 | 1997-05-26 | Bracco Spa | Macromolecole ramificate a struttura poliossialchilica e loro usi |
-
1995
- 1995-12-13 HU HU9702164A patent/HUT77521A/hu unknown
- 1995-12-13 WO PCT/EP1995/004933 patent/WO1996019240A1/en not_active Application Discontinuation
- 1995-12-13 EP EP95942147A patent/EP0790837A1/en not_active Withdrawn
- 1995-12-13 CA CA002206915A patent/CA2206915A1/en not_active Abandoned
- 1995-12-13 AU AU43446/96A patent/AU4344696A/en not_active Abandoned
- 1995-12-13 JP JP8519486A patent/JPH10510822A/ja active Pending
- 1995-12-19 IL IL11645695A patent/IL116456A0/xx unknown
-
1997
- 1997-06-16 FI FI972548A patent/FI972548A/fi not_active Application Discontinuation
- 1997-06-20 NO NO972868A patent/NO972868L/no unknown
Also Published As
Publication number | Publication date |
---|---|
CA2206915A1 (en) | 1996-06-27 |
NO972868D0 (no) | 1997-06-20 |
FI972548A (fi) | 1997-06-23 |
HUT77521A (hu) | 1998-05-28 |
IL116456A0 (en) | 1996-03-31 |
AU4344696A (en) | 1996-07-10 |
EP0790837A1 (en) | 1997-08-27 |
JPH10510822A (ja) | 1998-10-20 |
WO1996019240A1 (en) | 1996-06-27 |
FI972548A0 (fi) | 1997-06-16 |
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