NO970964L - Ortosubstituerte benzoylguanidiner, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende forbindelsene - Google Patents

Ortosubstituerte benzoylguanidiner, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende forbindelsene

Info

Publication number
NO970964L
NO970964L NO970964A NO970964A NO970964L NO 970964 L NO970964 L NO 970964L NO 970964 A NO970964 A NO 970964A NO 970964 A NO970964 A NO 970964A NO 970964 L NO970964 L NO 970964L
Authority
NO
Norway
Prior art keywords
atoms
processes
ortho
diagnostic
drug
Prior art date
Application number
NO970964A
Other languages
English (en)
Other versions
NO970964D0 (no
Inventor
Udo Albus
Joachim Brendel
Heinz-Werner Kleemann
Hans Jochen Lang
Wolfgang Scholz
Jan-Robert Schwark
Andreas Weichert
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO970964D0 publication Critical patent/NO970964D0/no
Publication of NO970964L publication Critical patent/NO970964L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/22—Y being a hydrogen or a carbon atom, e.g. benzoylguanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Abstract

Det er beskrevet ortosubstituerte benzoylgumidiner med formel (I): hvta- Sl(l) til R(4) kan ha mange betydninger, og blant annet ha følgende betydning: R(l) betyr H, F, Cl, alkyl med 1, 2, 3 eller 4 C-atomer, alkoksy med 1, 2, 3 eller 4 C-atomer, cykloalkyl med 5 eller 6 C-atomer, cykloalkoksy med^ 5 eller 6 C-atomer eller Xa-CF3; hvor X betyr oksygen og a er 0 eller 1; R(Z) og R(3) kan være definert som R(l) og R(<) kan f.eks. bety iretyl. Blsse forljlndelsene er egnede sora antlaiTtmiske legemidler med kardlobeskyttende komponenter for Infarkt- jrofyloksc og Infarktbehandl Infi samt for behandling av nnglna pectoris. De Inhiberer også preventivt de paLofyslologlske prosessene ved opptreden av Ischemlsk Induserte skader, spesielt ved utløsningen av Ischemlsk induserte hjertearytmier.
NO970964A 1996-03-04 1997-03-03 Ortosubstituerte benzoylguanidiner, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende forbindelsene NO970964L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19608162A DE19608162A1 (de) 1996-03-04 1996-03-04 Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Publications (2)

Publication Number Publication Date
NO970964D0 NO970964D0 (no) 1997-03-03
NO970964L true NO970964L (no) 1997-09-05

Family

ID=7787088

Family Applications (1)

Application Number Title Priority Date Filing Date
NO970964A NO970964L (no) 1996-03-04 1997-03-03 Ortosubstituerte benzoylguanidiner, fremgangsmåter for deres fremstilling, deres anvendelse som medikament eller diagnostikum samt medikamenter inneholdende forbindelsene

Country Status (22)

Country Link
US (1) US6153651A (no)
EP (1) EP0794171A3 (no)
JP (1) JPH09328462A (no)
KR (1) KR970065512A (no)
CN (1) CN1160041A (no)
AR (1) AR006052A1 (no)
AU (1) AU707403B2 (no)
BR (1) BR9701160A (no)
CA (1) CA2198979A1 (no)
CZ (1) CZ65397A3 (no)
DE (1) DE19608162A1 (no)
HR (1) HRP970126A2 (no)
HU (1) HUP9700543A3 (no)
IL (1) IL120359A0 (no)
MY (1) MY129959A (no)
NO (1) NO970964L (no)
NZ (1) NZ314326A (no)
PL (1) PL318416A1 (no)
SK (1) SK27597A3 (no)
TR (1) TR199700128A2 (no)
TW (1) TW386989B (no)
ZA (1) ZA971814B (no)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19624178A1 (de) * 1996-06-18 1998-01-08 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL34667C (no) * 1931-09-01
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
TW250477B (no) * 1992-12-15 1995-07-01 Hoechst Ag
IL109570A0 (en) * 1993-05-17 1994-08-26 Fujisawa Pharmaceutical Co Guanidine derivatives, pharmaceutical compositions containing the same and processes for the preparation thereof
DE4318658A1 (de) * 1993-06-04 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4318756A1 (de) * 1993-06-05 1994-12-08 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4325822A1 (de) * 1993-07-31 1995-02-02 Hoechst Ag Substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE4404183A1 (de) * 1994-02-10 1995-08-17 Merck Patent Gmbh 4-Amino-1-piperidylbenzoylguanidine
DE4421495A1 (de) * 1994-06-20 1995-12-21 Merck Patent Gmbh Heterocyclyloxy-benzoylguanidine
DE4430861A1 (de) * 1994-08-31 1996-03-07 Merck Patent Gmbh Heterocyclyl-benzoylguanidine

Also Published As

Publication number Publication date
TW386989B (en) 2000-04-11
TR199700128A2 (tr) 1997-09-21
DE19608162A1 (de) 1997-09-11
ZA971814B (en) 1997-09-04
CA2198979A1 (en) 1997-09-04
NO970964D0 (no) 1997-03-03
CN1160041A (zh) 1997-09-24
AU707403B2 (en) 1999-07-08
HUP9700543A2 (en) 1997-12-29
EP0794171A2 (de) 1997-09-10
SK27597A3 (en) 1997-11-05
IL120359A0 (en) 1997-07-13
AU1499897A (en) 1997-09-11
MX9701618A (es) 1997-09-30
CZ65397A3 (cs) 1998-05-13
NZ314326A (en) 1997-11-24
EP0794171A3 (de) 1998-08-19
US6153651A (en) 2000-11-28
MY129959A (en) 2007-05-31
HU9700543D0 (en) 1997-04-28
JPH09328462A (ja) 1997-12-22
HUP9700543A3 (en) 2000-03-28
HRP970126A2 (en) 1998-04-30
KR970065512A (ko) 1997-10-13
PL318416A1 (en) 1997-09-15
AR006052A1 (es) 1999-07-21
BR9701160A (pt) 1998-12-15

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