NO970127L - Topiske sammensetninger for behandling av hudsykdom - Google Patents

Topiske sammensetninger for behandling av hudsykdom

Info

Publication number
NO970127L
NO970127L NO970127A NO970127A NO970127L NO 970127 L NO970127 L NO 970127L NO 970127 A NO970127 A NO 970127A NO 970127 A NO970127 A NO 970127A NO 970127 L NO970127 L NO 970127L
Authority
NO
Norway
Prior art keywords
aryl
hydrogen
lower alkyl
independently
treatment
Prior art date
Application number
NO970127A
Other languages
English (en)
Other versions
NO970127D0 (no
Inventor
William Taylor
Judith Melance Wright
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO970127D0 publication Critical patent/NO970127D0/no
Publication of NO970127L publication Critical patent/NO970127L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/4035Isoindoles, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Sammensetning egnet for topisk administrering for behandling av en hyperproiifcrativ hudsykdom som er en gel omfattende (A) en forbindelse med formelen Ar, A,-N Aj-N Ar, O // N-R a) hvor Al og A2 hver er uavhengig av hverandre hydrogen, lavere alkyl, lavere alkenyl, lavere alk7nyl, aryl, acyl, lavere alkylsulfonyl eller arylsulfonyl; eller hvor A\ og A2 sammen danner usubstituert eller lavere alkyl- eller hydroksy-substituert lavere alkylen; At] og Ar2 er hver uavhengig av hverandre aryl, heteroaryl eller usubstituert eller substituert cyklDalk7l; gruppen -C(=X)- er -C(=0)-, -C(=S)-, -CH2- eller - C(=CRi R2)- hvor Rj og R2 er hver, uavhengig av hverandre, hydrogen eller lavere alkyl; og R er hydrogen, lavere alkyl, aryl-lavere alkyl, aryl, amino, hydroksy eller lavere alkoksy; forutsatt at R er forskjellig fra fenyl når A] og A2 er hydrogen. Ar] og Ar2 er fenyl og gmppen -C(=X)- er -C(=G)-; eller et farmasoyiisk akseptabelt salt derav når en saltdannende gruppe er tilstede; (B) enCi-C4 alkylmonoeter av dietylenglykol, (C) et geldarmende middel, og (D) et opnlosningsm.iddel som er blandbart med (B).
NO970127A 1996-01-11 1997-01-10 Topiske sammensetninger for behandling av hudsykdom NO970127L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9600545.9A GB9600545D0 (en) 1996-01-11 1996-01-11 Compositions

Publications (2)

Publication Number Publication Date
NO970127D0 NO970127D0 (no) 1997-01-10
NO970127L true NO970127L (no) 1997-07-14

Family

ID=10786892

Family Applications (1)

Application Number Title Priority Date Filing Date
NO970127A NO970127L (no) 1996-01-11 1997-01-10 Topiske sammensetninger for behandling av hudsykdom

Country Status (11)

Country Link
EP (1) EP0783887A3 (no)
JP (1) JPH09194371A (no)
KR (1) KR970058711A (no)
AU (1) AU1002697A (no)
CA (1) CA2194730A1 (no)
GB (1) GB9600545D0 (no)
HU (1) HUP9700079A2 (no)
IL (1) IL119990A0 (no)
MX (1) MX9700324A (no)
NO (1) NO970127L (no)
ZA (1) ZA97253B (no)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101193641B (zh) * 2005-05-10 2013-05-29 德米普瑟尔有限公司 用于治疗表皮过度增殖疾病的组合物和方法
JP7254027B2 (ja) * 2016-12-19 2023-04-07 ディームバイオント・インコーポレイテッド 色素沈着過剰障害の処置方法
EP4525862A1 (en) 2022-05-20 2025-03-26 Dermbiont, Inc. Compositions and formulations for use of a pk inhibitor for the prevention, treatment, and improvement of skin diseases, conditions, and disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU653024B2 (en) * 1991-05-30 1994-09-15 Novartis Ag Substituted diaminophthalimides and analogues
WO1994007895A1 (en) * 1992-09-25 1994-04-14 Schering Corporation Diindolo compounds and pharmaceutical compositions containing them
AU686691B2 (en) * 1994-01-12 1998-02-12 F. Hoffmann-La Roche Ag Novel azepanes and homologs thereof

Also Published As

Publication number Publication date
AU1002697A (en) 1997-07-17
GB9600545D0 (en) 1996-03-13
CA2194730A1 (en) 1997-07-12
KR970058711A (ko) 1997-08-12
ZA97253B (en) 1997-07-13
IL119990A0 (en) 1997-04-15
MX9700324A (es) 1998-04-30
HUP9700079A2 (hu) 1998-05-28
HU9700079D0 (en) 1997-02-28
JPH09194371A (ja) 1997-07-29
NO970127D0 (no) 1997-01-10
EP0783887A2 (en) 1997-07-16
EP0783887A3 (en) 1999-01-20

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