NO964268L - Antiadhesive piperidin- og pyrrolidin-karboksylsyrer - Google Patents
Antiadhesive piperidin- og pyrrolidin-karboksylsyrerInfo
- Publication number
- NO964268L NO964268L NO964268A NO964268A NO964268L NO 964268 L NO964268 L NO 964268L NO 964268 A NO964268 A NO 964268A NO 964268 A NO964268 A NO 964268A NO 964268 L NO964268 L NO 964268L
- Authority
- NO
- Norway
- Prior art keywords
- piperidine
- antiadhesive
- carboxylic acids
- pyrrolidine carboxylic
- ring
- Prior art date
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title abstract 4
- 230000000181 anti-adherent effect Effects 0.000 title 1
- NYCVCXMSZNOGDH-UHFFFAOYSA-N pyrrolidine-1-carboxylic acid Chemical class OC(=O)N1CCCC1 NYCVCXMSZNOGDH-UHFFFAOYSA-N 0.000 title 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 150000002243 furanoses Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003053 piperidines Chemical class 0.000 abstract 1
- 150000003215 pyranoses Chemical class 0.000 abstract 1
- 150000003235 pyrrolidines Chemical class 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/207—Cyclohexane rings not substituted by nitrogen atoms, e.g. kasugamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19537334A DE19537334A1 (de) | 1995-10-09 | 1995-10-09 | Antiadhäsive Piperidin- und Pyrrolidin-Carbonsäuren |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO964268D0 NO964268D0 (no) | 1996-10-08 |
| NO964268L true NO964268L (no) | 1997-04-10 |
Family
ID=7774241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO964268A NO964268L (no) | 1995-10-09 | 1996-10-08 | Antiadhesive piperidin- og pyrrolidin-karboksylsyrer |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5739300A (zh) |
| EP (1) | EP0787739B1 (zh) |
| JP (1) | JPH09110834A (zh) |
| KR (1) | KR970021071A (zh) |
| CN (1) | CN1150155A (zh) |
| AT (1) | ATE231877T1 (zh) |
| AU (1) | AU6799796A (zh) |
| BR (1) | BR9605024A (zh) |
| CA (1) | CA2187392A1 (zh) |
| CZ (1) | CZ294096A3 (zh) |
| DE (2) | DE19537334A1 (zh) |
| HR (1) | HRP960459A2 (zh) |
| HU (1) | HUP9602745A3 (zh) |
| MX (1) | MX9604657A (zh) |
| NO (1) | NO964268L (zh) |
| PL (1) | PL316429A1 (zh) |
| SI (1) | SI9600296A (zh) |
| SK (1) | SK127796A3 (zh) |
| TR (1) | TR199600799A2 (zh) |
| ZA (1) | ZA968470B (zh) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU1804299A (en) * | 1997-12-08 | 1999-06-28 | Glycomed Incorporated | Sialyl lewis x and sialyl lewis a glycomimetics |
| JP5183010B2 (ja) | 2002-05-16 | 2013-04-17 | グリコミメティクス， インコーポレイテッド | セレクチンによって媒介される機能を阻害するための化合物および方法 |
| EP1511488B1 (en) | 2002-06-12 | 2013-05-22 | Symphony Evolution, Inc. | Human adam-10 inhibitors |
| JP2006502986A (ja) * | 2002-07-03 | 2006-01-26 | グリコミメティクス， インコーポレイテッド | 新脈管形成に関与する医学的状態の診断および治療のための組成物および方法 |
| US20040219158A1 (en) * | 2003-05-02 | 2004-11-04 | Glycomimetics, Inc. | Compositions and methods for diagnosis and therapy of medical conditions involving infection with pseudomonas bacteria |
| US7361644B2 (en) * | 2003-11-19 | 2008-04-22 | Glycomimetics, Inc. | Specific antagonist for both E- and P-selectins |
| EP1685145A2 (en) * | 2003-11-19 | 2006-08-02 | GlycoMimetics, Inc. | Glycomimetic antagonists for both e- and p-selectins |
| US8201377B2 (en) * | 2004-11-05 | 2012-06-19 | Faus Group, Inc. | Flooring system having multiple alignment points |
| WO2006127906A1 (en) * | 2005-05-25 | 2006-11-30 | Glycomimetics, Inc. | Heterobifunctional compounds for selectin inhibition |
| ES2375979T3 (es) * | 2005-08-09 | 2012-03-07 | Glycomimetics, Inc. | Inhibidores glicomiméticos de la lectina pa-il, lectina pa-iil o ambas lectinas de pseudomonas. |
| DK2264043T3 (da) | 2005-09-02 | 2018-01-29 | Glycomimetics Inc | Heterobifunktionelle pan-selektin-inhibitorer |
| US20090176717A1 (en) * | 2006-06-01 | 2009-07-09 | Glycomimetics, Inc. | Galactosides and thiodigalactosides as inhibitors of pa-il lectin from pseudomonas |
| CA2666103C (en) | 2006-10-12 | 2014-02-18 | Glycomimetics, Inc. | Glycomimetic replacements for hexoses and n-acetyl hexosamines |
| EP2117561A1 (en) * | 2007-02-09 | 2009-11-18 | GlycoMimetics, Inc. | Methods of use of glycomimetics with replacements for hexoses and n-acetyl hexosamines |
| US8039442B2 (en) | 2007-07-18 | 2011-10-18 | Glycomimetics, Inc. | Compounds and methods for treatment of sickle cell disease or complications associated therewith |
| US8895510B2 (en) * | 2008-04-08 | 2014-11-25 | Glycomimetics, Inc. | Pan-selectin inhibitor with enhanced pharmacokinetic activity |
| WO2009152245A1 (en) * | 2008-06-13 | 2009-12-17 | Glycomimetics, Inc. | Treatment of cancers of the blood using selected glycomimetic compounds |
| AU2010241807B2 (en) * | 2009-05-01 | 2014-08-14 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectins and CXCR4 chemokine receptors |
| US8921328B2 (en) | 2010-09-14 | 2014-12-30 | Glycomimetics, Inc. | E-selectin antagonists |
| KR102055958B1 (ko) | 2011-12-22 | 2019-12-13 | 글리코미메틱스, 인크. | E-셀렉틴 길항제 화합물, 조성물, 및 이용 방법 |
| US9867841B2 (en) | 2012-12-07 | 2018-01-16 | Glycomimetics, Inc. | Compounds, compositions and methods using E-selectin antagonists for mobilization of hematopoietic cells |
| JP6689854B2 (ja) | 2014-12-03 | 2020-04-28 | グリコミメティクス， インコーポレイテッド | Ｅ−セレクチンおよびｃｘｃｒ４ケモカイン受容体のヘテロ二官能性阻害剤 |
| CA3009836A1 (en) | 2016-01-22 | 2017-07-27 | Glycomimetics, Inc. | Glycomimetic inhibitors of pa-il and pa-iil lectins |
| WO2017151708A1 (en) | 2016-03-02 | 2017-09-08 | Glycomimetics, Inc. | Methods for the treatment and/or prevention of cardiovescular disease by inhibition of e-selectin |
| EP3497131B1 (en) | 2016-08-08 | 2022-03-09 | GlycoMimetics, Inc. | Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4. |
| KR102607640B1 (ko) | 2016-10-07 | 2023-11-28 | 글리코미메틱스, 인크. | 매우 강력한 다량체성 e-셀렉틴 길항물질 |
| US11197877B2 (en) | 2017-03-15 | 2021-12-14 | Glycomimetics. Inc. | Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists |
| EP3717013A1 (en) | 2017-11-30 | 2020-10-07 | GlycoMimetics, Inc. | Methods of mobilizing marrow infiltrating lymphocytes and uses thereof |
| AU2018395417B2 (en) | 2017-12-29 | 2023-07-13 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
| CA3091454A1 (en) | 2018-03-05 | 2019-09-12 | Glycomimetics, Inc. | Methods for treating acute myeloid leukemia and related conditions |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0671409A3 (de) * | 1994-03-11 | 1996-06-12 | Hoechst Ag | Malonsäurederivate mit antiadhäsiven Eigenschaften. |
-
1995
- 1995-10-09 DE DE19537334A patent/DE19537334A1/de not_active Withdrawn
-
1996
- 1996-09-26 AT AT96115414T patent/ATE231877T1/de not_active IP Right Cessation
- 1996-09-26 EP EP96115414A patent/EP0787739B1/de not_active Expired - Lifetime
- 1996-09-26 DE DE59610093T patent/DE59610093D1/de not_active Expired - Lifetime
- 1996-10-04 SK SK1277-96A patent/SK127796A3/sk unknown
- 1996-10-04 US US08/726,142 patent/US5739300A/en not_active Expired - Fee Related
- 1996-10-07 AU AU67997/96A patent/AU6799796A/en not_active Abandoned
- 1996-10-07 CN CN96113073A patent/CN1150155A/zh active Pending
- 1996-10-07 TR TR96/00799A patent/TR199600799A2/xx unknown
- 1996-10-07 HR HR19537334.0A patent/HRP960459A2/hr not_active Application Discontinuation
- 1996-10-07 PL PL96316429A patent/PL316429A1/xx unknown
- 1996-10-07 CZ CZ962940A patent/CZ294096A3/cs unknown
- 1996-10-07 HU HU9602745A patent/HUP9602745A3/hu unknown
- 1996-10-08 CA CA002187392A patent/CA2187392A1/en not_active Abandoned
- 1996-10-08 JP JP8267002A patent/JPH09110834A/ja active Pending
- 1996-10-08 SI SI9600296A patent/SI9600296A/sl unknown
- 1996-10-08 NO NO964268A patent/NO964268L/no unknown
- 1996-10-08 BR BR9605024A patent/BR9605024A/pt not_active Application Discontinuation
- 1996-10-08 MX MX9604657A patent/MX9604657A/es unknown
- 1996-10-08 ZA ZA968470A patent/ZA968470B/xx unknown
- 1996-10-09 KR KR1019960044663A patent/KR970021071A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| HU9602745D0 (en) | 1996-11-28 |
| DE19537334A1 (de) | 1997-04-10 |
| HUP9602745A2 (en) | 1997-05-28 |
| SK127796A3 (en) | 1997-05-07 |
| US5739300A (en) | 1998-04-14 |
| DE59610093D1 (de) | 2003-03-06 |
| JPH09110834A (ja) | 1997-04-28 |
| TR199600799A2 (tr) | 1997-04-22 |
| ZA968470B (en) | 1997-04-09 |
| MX9604657A (es) | 1998-04-30 |
| EP0787739B1 (de) | 2003-01-29 |
| KR970021071A (ko) | 1997-05-28 |
| PL316429A1 (en) | 1997-04-14 |
| CZ294096A3 (en) | 1997-04-16 |
| ATE231877T1 (de) | 2003-02-15 |
| BR9605024A (pt) | 1998-06-30 |
| CN1150155A (zh) | 1997-05-21 |
| NO964268D0 (no) | 1996-10-08 |
| EP0787739A1 (de) | 1997-08-06 |
| HUP9602745A3 (en) | 1998-03-02 |
| HRP960459A2 (en) | 1998-02-28 |
| SI9600296A (en) | 1997-04-30 |
| AU6799796A (en) | 1997-04-17 |
| CA2187392A1 (en) | 1997-04-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO964268L (no) | Antiadhesive piperidin- og pyrrolidin-karboksylsyrer | |
| DE68917881D1 (de) | Ansteuerungssignalerzeuger für in Halbbrückenanordnung verbundene Transistoren. | |
| NO891988L (no) | Anordning og fremgangsmaate for maaling eller inngrep i en broenn, samt anvendelse av anordningen. | |
| DE68908337D1 (de) | Drehmomentmessfuehler. | |
| ID16329A (id) | Metode untuk membuka cetakan puputan yang terbuka pada bagian ujung bawah dengan pencetakan secara suntikan | |
| DE68911975D1 (de) | Ophthalmoskopisches Diagnoseverfahren und Gerät. | |
| DE69023792D1 (de) | Ultraschallgenerator und akustisches Mikroskop mit Ultraschall. | |
| DE68905755D1 (de) | Drehmomentmessfuehler. | |
| FR2656308B1 (fr) | Derives du glycerol, ainsi que leur procede de preparation. | |
| DE3887053D1 (de) | Stlv-iii-verwandte polypeptide, diagnosesysteme und testmethoden. | |
| FR2704068B1 (fr) | Chapelet de sondes perfectionne. | |
| DE68910134D1 (de) | Homogener enzymimmuntest. | |
| FI963638A0 (fi) | Menetelmiä HIV-1-injektion diagnosoimiseksi ja hoitamiseksi | |
| DE69708967T2 (de) | Carbodiimide mit Doppelbindungen | |
| DE59706367D1 (de) | Überwachungsorgan mit Prüfstrahl im Zusammenhang mit Verpackungsmaschinen | |
| NO913568D0 (no) | Hydraulisk aktivisert broennventil, samt fremgangsmaate fortesting av formasjoner. | |
| WO2001006250A3 (en) | Thermo-chemical sensors and uses thereof | |
| NO972046L (no) | Antistoff mot allogene og xenogene proteiner, deres bruk i diagnose og terapi samt fremgangsmåter for bestemmelse av slike | |
| DE19780326T1 (de) | Verbesserungen im Hinblick auf die Herstellung von Antikörpern, Test-Kits mit Antikörpern und medizinische Anwendung mit Antikörpern | |
| TW350777B (en) | Stimulation device | |
| BR8802411A (pt) | Aperfeicoamento introduzido em aparelho de teste de aplicacao de tintas | |
| TH1001001206B (th) | อนุพันธ์ต่างๆ ของกรดคาร์บอกซิลิกชนิดใหม่, วิธีการเตรียมและการใช้ประโยชน์ของอนุพันธ์ต่างๆของกรดคาร์บอกซิลิกชนิดใหม่ | |
| NO893597L (no) | Fremgangsmaate og innretning for reparasjon av foringsroer o.l. | |
| BR1100085A (pt) | derivados de benzisoxazol e benzisotisol com inibidores de colinesterase. | |
| NO923828D0 (no) | Polypeptider, nyttige til diagnose av og behandling mot mycoplasma-infeksjoner hos dyr |