NO964268L - Antiadhesive piperidin- og pyrrolidin-karboksylsyrer - Google Patents
Antiadhesive piperidin- og pyrrolidin-karboksylsyrerInfo
- Publication number
- NO964268L NO964268L NO964268A NO964268A NO964268L NO 964268 L NO964268 L NO 964268L NO 964268 A NO964268 A NO 964268A NO 964268 A NO964268 A NO 964268A NO 964268 L NO964268 L NO 964268L
- Authority
- NO
- Norway
- Prior art keywords
- piperidine
- antiadhesive
- carboxylic acids
- pyrrolidine carboxylic
- ring
- Prior art date
Links
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title abstract 4
- 230000000181 anti-adherent effect Effects 0.000 title 1
- NYCVCXMSZNOGDH-UHFFFAOYSA-N pyrrolidine-1-carboxylic acid Chemical class OC(=O)N1CCCC1 NYCVCXMSZNOGDH-UHFFFAOYSA-N 0.000 title 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 150000002243 furanoses Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 150000003053 piperidines Chemical class 0.000 abstract 1
- 150000003215 pyranoses Chemical class 0.000 abstract 1
- 150000003235 pyrrolidines Chemical class 0.000 abstract 1
- 150000005846 sugar alcohols Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/207—Cyclohexane rings not substituted by nitrogen atoms, e.g. kasugamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Heart & Thoracic Surgery (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Transplantation (AREA)
- Vascular Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyrrole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19537334A DE19537334A1 (de) | 1995-10-09 | 1995-10-09 | Antiadhäsive Piperidin- und Pyrrolidin-Carbonsäuren |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO964268D0 NO964268D0 (no) | 1996-10-08 |
| NO964268L true NO964268L (no) | 1997-04-10 |
Family
ID=7774241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO964268A NO964268L (no) | 1995-10-09 | 1996-10-08 | Antiadhesive piperidin- og pyrrolidin-karboksylsyrer |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US5739300A (sk) |
| EP (1) | EP0787739B1 (sk) |
| JP (1) | JPH09110834A (sk) |
| KR (1) | KR970021071A (sk) |
| CN (1) | CN1150155A (sk) |
| AT (1) | ATE231877T1 (sk) |
| AU (1) | AU6799796A (sk) |
| BR (1) | BR9605024A (sk) |
| CA (1) | CA2187392A1 (sk) |
| CZ (1) | CZ294096A3 (sk) |
| DE (2) | DE19537334A1 (sk) |
| HR (1) | HRP960459A2 (sk) |
| HU (1) | HUP9602745A3 (sk) |
| MX (1) | MX9604657A (sk) |
| NO (1) | NO964268L (sk) |
| PL (1) | PL316429A1 (sk) |
| SI (1) | SI9600296A (sk) |
| SK (1) | SK127796A3 (sk) |
| TR (1) | TR199600799A2 (sk) |
| ZA (1) | ZA968470B (sk) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1999029705A2 (en) * | 1997-12-08 | 1999-06-17 | Glycomed Incorporated | Sialyl lewis x and sialyl lewis a glycomimetics |
| AU2003249641B2 (en) | 2002-05-16 | 2009-08-20 | Glycomimetics, Inc. | Compounds and methods for inhibiting selectin-mediated function |
| EP1511488B1 (en) | 2002-06-12 | 2013-05-22 | Symphony Evolution, Inc. | Human adam-10 inhibitors |
| US20040096396A1 (en) * | 2002-07-03 | 2004-05-20 | Glycomimetics, Inc. | Compositions and methods for diagnosis and therapy of medical conditions involving angiogenesis |
| US20040219158A1 (en) * | 2003-05-02 | 2004-11-04 | Glycomimetics, Inc. | Compositions and methods for diagnosis and therapy of medical conditions involving infection with pseudomonas bacteria |
| US20050187171A1 (en) * | 2003-11-19 | 2005-08-25 | Glycomimetics, Inc. | Glycomimetic antagonists for both E-and P-selectins |
| US7361644B2 (en) * | 2003-11-19 | 2008-04-22 | Glycomimetics, Inc. | Specific antagonist for both E- and P-selectins |
| US8201377B2 (en) * | 2004-11-05 | 2012-06-19 | Faus Group, Inc. | Flooring system having multiple alignment points |
| US20090036386A1 (en) * | 2005-05-25 | 2009-02-05 | Glycomimetics, Inc | Heterobifunctional compounds for selectin inhibition |
| ATE528311T1 (de) * | 2005-08-09 | 2011-10-15 | Glycomimetics Inc | Glycomimetische inhibitoren des pa-il-lectins, pa-iil-lectins oder beider lectine aus pseudomonas |
| JP5209476B2 (ja) | 2005-09-02 | 2013-06-12 | グリコミメティクス， インコーポレイテッド | ヘテロ二官能性全セレクチン阻害剤 |
| WO2007143052A1 (en) * | 2006-06-01 | 2007-12-13 | Glycomimetics, Inc. | Galactosides and thiodigalactosides as inhibitors of pa-il lectin from pseudomonas |
| EP2074132B1 (en) | 2006-10-12 | 2013-05-15 | GlycoMimetics, Inc. | Glycomimetic replacements for hexoses and n-acetyl hexosamines |
| CA2677747A1 (en) * | 2007-02-09 | 2008-08-21 | Glycomimetics, Inc. | Methods of use of glycomimetics with replacements for hexoses and n-acetyl hexosamines |
| US8039442B2 (en) | 2007-07-18 | 2011-10-18 | Glycomimetics, Inc. | Compounds and methods for treatment of sickle cell disease or complications associated therewith |
| US8895510B2 (en) | 2008-04-08 | 2014-11-25 | Glycomimetics, Inc. | Pan-selectin inhibitor with enhanced pharmacokinetic activity |
| CN102088983B (zh) * | 2008-06-13 | 2013-01-30 | 糖模拟物有限公司 | 利用选择的糖模拟化合物的血液癌症的治疗 |
| CA2760292A1 (en) * | 2009-05-01 | 2010-11-04 | Glycomimetics, Inc. | Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors |
| WO2012037034A1 (en) | 2010-09-14 | 2012-03-22 | Glycomimetics, Inc. | E-selectin antagonists |
| AU2012358150B2 (en) | 2011-12-22 | 2017-07-20 | Glycomimetics, Inc. | E-selectin antagonist compounds, compositions, and methods of use |
| CA2891514C (en) | 2012-12-07 | 2020-08-25 | Glycomimetics, Inc. | Compounds, compositions and methods using e-selectin antagonists for mobilization of hematopoietic cells |
| CA2968391C (en) | 2014-12-03 | 2022-04-26 | Glycomimetics, Inc. | Heterobifunctional inhibitors of e-selectins and cxcr4 chemokine receptors |
| WO2017127422A1 (en) | 2016-01-22 | 2017-07-27 | Glycomimetics, Inc. | Glycomimetic inhibitors of pa-il and pa-iil lectins |
| US11291678B2 (en) | 2016-03-02 | 2022-04-05 | Glycomimetics, Inc | Methods for the treatment and/or prevention of cardiovascular disease by inhibition of E-selectin |
| EP3497131B1 (en) | 2016-08-08 | 2022-03-09 | GlycoMimetics, Inc. | Combination of t-cell checkpoint inhibitors with inhibitors of e-selectin or cxcr4, or with heterobifunctional inhibitors of both e-selectin and cxcr4. |
| JP7069136B2 (ja) | 2016-10-07 | 2022-05-17 | グリコミメティクス， インコーポレイテッド | 極めて強力な多量体ｅ－セレクチンアンタゴニスト |
| US11197877B2 (en) | 2017-03-15 | 2021-12-14 | Glycomimetics. Inc. | Galactopyranosyl-cyclohexyl derivauves as E-selectin antagonists |
| US11712446B2 (en) | 2017-11-30 | 2023-08-01 | Glycomimetics, Inc. | Methods of mobilizing marrow infiltrating lymphocytes and uses thereof |
| EP3732186A1 (en) | 2017-12-29 | 2020-11-04 | GlycoMimetics, Inc. | Heterobifunctional inhibitors of e-selectin and galectin-3 |
| CN111867601A (zh) | 2018-03-05 | 2020-10-30 | 糖模拟物有限公司 | 用于治疗急性髓系白血病及相关病症的方法 |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0671409A3 (de) * | 1994-03-11 | 1996-06-12 | Hoechst Ag | Malonsäurederivate mit antiadhäsiven Eigenschaften. |
-
1995
- 1995-10-09 DE DE19537334A patent/DE19537334A1/de not_active Withdrawn
-
1996
- 1996-09-26 DE DE59610093T patent/DE59610093D1/de not_active Expired - Lifetime
- 1996-09-26 EP EP96115414A patent/EP0787739B1/de not_active Expired - Lifetime
- 1996-09-26 AT AT96115414T patent/ATE231877T1/de not_active IP Right Cessation
- 1996-10-04 US US08/726,142 patent/US5739300A/en not_active Expired - Fee Related
- 1996-10-04 SK SK1277-96A patent/SK127796A3/sk unknown
- 1996-10-07 TR TR96/00799A patent/TR199600799A2/xx unknown
- 1996-10-07 PL PL96316429A patent/PL316429A1/xx unknown
- 1996-10-07 HU HU9602745A patent/HUP9602745A3/hu unknown
- 1996-10-07 CN CN96113073A patent/CN1150155A/zh active Pending
- 1996-10-07 CZ CZ962940A patent/CZ294096A3/cs unknown
- 1996-10-07 AU AU67997/96A patent/AU6799796A/en not_active Abandoned
- 1996-10-07 HR HR19537334.0A patent/HRP960459A2/hr not_active Application Discontinuation
- 1996-10-08 ZA ZA968470A patent/ZA968470B/xx unknown
- 1996-10-08 NO NO964268A patent/NO964268L/no unknown
- 1996-10-08 MX MX9604657A patent/MX9604657A/es unknown
- 1996-10-08 CA CA002187392A patent/CA2187392A1/en not_active Abandoned
- 1996-10-08 BR BR9605024A patent/BR9605024A/pt not_active Application Discontinuation
- 1996-10-08 JP JP8267002A patent/JPH09110834A/ja active Pending
- 1996-10-08 SI SI9600296A patent/SI9600296A/sl unknown
- 1996-10-09 KR KR1019960044663A patent/KR970021071A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US5739300A (en) | 1998-04-14 |
| JPH09110834A (ja) | 1997-04-28 |
| HUP9602745A2 (en) | 1997-05-28 |
| CA2187392A1 (en) | 1997-04-10 |
| ZA968470B (en) | 1997-04-09 |
| CN1150155A (zh) | 1997-05-21 |
| HUP9602745A3 (en) | 1998-03-02 |
| HRP960459A2 (en) | 1998-02-28 |
| EP0787739A1 (de) | 1997-08-06 |
| TR199600799A2 (tr) | 1997-04-22 |
| CZ294096A3 (en) | 1997-04-16 |
| EP0787739B1 (de) | 2003-01-29 |
| PL316429A1 (en) | 1997-04-14 |
| BR9605024A (pt) | 1998-06-30 |
| ATE231877T1 (de) | 2003-02-15 |
| NO964268D0 (no) | 1996-10-08 |
| HU9602745D0 (en) | 1996-11-28 |
| MX9604657A (es) | 1998-04-30 |
| KR970021071A (ko) | 1997-05-28 |
| SI9600296A (en) | 1997-04-30 |
| DE59610093D1 (de) | 2003-03-06 |
| DE19537334A1 (de) | 1997-04-10 |
| SK127796A3 (en) | 1997-05-07 |
| AU6799796A (en) | 1997-04-17 |
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