NO963568L - Farmasöytisk preparat for behandling av blodkoagulasjonssykdommer, fremgangsmåter for fremstilling av dette og dets anvendelse - Google Patents
Farmasöytisk preparat for behandling av blodkoagulasjonssykdommer, fremgangsmåter for fremstilling av dette og dets anvendelseInfo
- Publication number
- NO963568L NO963568L NO963568A NO963568A NO963568L NO 963568 L NO963568 L NO 963568L NO 963568 A NO963568 A NO 963568A NO 963568 A NO963568 A NO 963568A NO 963568 L NO963568 L NO 963568L
- Authority
- NO
- Norway
- Prior art keywords
- factor
- feiba
- coagulation
- pharmaceutical preparation
- activity
- Prior art date
Links
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6437—Coagulation factor VIIa (3.4.21.21)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4846—Factor VII (3.4.21.21); Factor IX (3.4.21.22); Factor Xa (3.4.21.6); Factor XI (3.4.21.27); Factor XII (3.4.21.38)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/647—Blood coagulation factors not provided for in a preceding group or according to more than one of the proceeding groups
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21021—Coagulation factor VIIa (3.4.21.21)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19531637A DE19531637A1 (de) | 1995-08-28 | 1995-08-28 | Pharmazeutische Zusammensetzung zur Behandlung von Blutgerinnungsstörugnen, Verfahren zur Herstellung derselben und deren Verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO963568D0 NO963568D0 (no) | 1996-08-27 |
| NO963568L true NO963568L (no) | 1997-03-03 |
Family
ID=7770599
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO963568A NO963568L (no) | 1995-08-28 | 1996-08-27 | Farmasöytisk preparat for behandling av blodkoagulasjonssykdommer, fremgangsmåter for fremstilling av dette og dets anvendelse |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US5891843A (fr) |
| EP (1) | EP0765669A1 (fr) |
| JP (1) | JPH09110715A (fr) |
| CA (1) | CA2184226A1 (fr) |
| DE (1) | DE19531637A1 (fr) |
| NO (1) | NO963568L (fr) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0796623B1 (fr) * | 1996-03-20 | 2005-05-25 | Baxter Aktiengesellschaft | Préparation pharmaceutique pour le traitement des maladies de la coagulation sanguine |
| PT973544E (pt) * | 1997-04-08 | 2001-12-28 | Baxter Ag | Preparacao de complexo de protrombina imunotolerante |
| AT405608B (de) * | 1997-04-08 | 1999-10-25 | Immuno Ag | Verfahren zur inaktivierung von pathogenen, insbesondere von viren, in einem biologischen material |
| US20050032690A1 (en) * | 1997-09-10 | 2005-02-10 | Rojkjaer Lisa Payne | Factor VII polypeptides for preventing formation of inhibitors in subjects with haemophilia |
| ATA159597A (de) * | 1997-09-19 | 2000-09-15 | Immuno Ag | Präparat zur behandlung von blutgerinnungsstörungen |
| US7247708B2 (en) | 1997-10-23 | 2007-07-24 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US6747003B1 (en) | 1997-10-23 | 2004-06-08 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| AT408613B (de) * | 1998-06-17 | 2002-01-25 | Immuno Ag | Pharmazeutisches faktor vii-präparat |
| JP4676585B2 (ja) | 1999-12-24 | 2011-04-27 | 一般財団法人化学及血清療法研究所 | 血液凝固異常に基づく疾患の治療・予防用医薬組成物 |
| ATE428445T1 (de) | 2000-02-11 | 2009-05-15 | Bayer Healthcare Llc | Gerinnungsfaktor vii oder viia konjugate |
| DE10012732A1 (de) * | 2000-03-18 | 2001-09-20 | Aventis Behring Gmbh | Thrombin-Zubereitungen und Verfahren zu ihrer Herstellung |
| US7220837B1 (en) | 2000-04-28 | 2007-05-22 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US7812132B2 (en) | 2000-04-28 | 2010-10-12 | Regents Of The University Of Minnesota | Modified vitamin K-dependent polypeptides |
| US20030211094A1 (en) | 2001-06-26 | 2003-11-13 | Nelsestuen Gary L. | High molecular weight derivatives of vitamin k-dependent polypeptides |
| US20030203845A1 (en) * | 2001-02-05 | 2003-10-30 | Knudsen Jens Bjerre | Combined use of factor VII polypeptides and factor IX polypeptides |
| JP2004517949A (ja) * | 2001-02-05 | 2004-06-17 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | 第ｖｉｉ因子ポリペプチド及び第ｉｘ因子ポリペプチドの組合された使用 |
| CA2452395C (fr) * | 2001-07-10 | 2012-04-10 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Compositions hemostatiques pharmaceutiquement stables |
| DE60232017D1 (de) | 2001-12-21 | 2009-05-28 | Novo Nordisk Healthcare Ag | Flüssige zusammensetzung aus faktor vii polypeptiden |
| PL373728A1 (en) * | 2002-04-30 | 2005-09-05 | Maxygen Holdings Ltd. | Factor vii or viia polypeptide variants |
| JP4648002B2 (ja) | 2002-06-21 | 2011-03-09 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | 第ｖｉｉ因子ポリペプチドの安定化された固体組成物 |
| CA2499458C (fr) * | 2002-09-30 | 2013-11-12 | Socratech L.L.C. | Proteine s protegeant le systeme nerveux contre les lesions |
| US20040198660A1 (en) * | 2002-11-06 | 2004-10-07 | Petersen Lars Christian | Tissue factor antagonist and protein C polypeptide compositions |
| US20070142272A1 (en) * | 2003-01-24 | 2007-06-21 | Zlokovic Berislav V | Neuroprotective activity of activated protein c independent of its anticoagulant activity |
| EP1611236A1 (fr) | 2003-03-18 | 2006-01-04 | Novo Nordisk Health Care AG | Procede de production de protease seriniques contenant des residus d'acide gamma-carboxyglutamique |
| ES2327044T3 (es) * | 2003-03-20 | 2009-10-23 | Bayer Healthcare Llc | Variantes de fvii o fviia. |
| US7897734B2 (en) | 2003-03-26 | 2011-03-01 | Novo Nordisk Healthcare Ag | Method for the production of proteins |
| US7977460B2 (en) * | 2003-05-19 | 2011-07-12 | National Institute For Biological Standards And Control | Compositions comprising coagulation factors IXA and VIII for the treatment of haemophilia A or B |
| EP1628677B1 (fr) | 2003-05-23 | 2010-01-13 | Novo Nordisk Health Care AG | Stabilisation de proteines dans une solution |
| JP4915918B2 (ja) * | 2003-06-19 | 2012-04-11 | バイエル ヘルスケア エルエルシー | 第ＶＩＩ因子または第ＶＩＩａ因子のＧｌａドメイン変種 |
| ATE547114T1 (de) | 2003-06-25 | 2012-03-15 | Novo Nordisk Healthcare Ag | Flüssige zusammensetzungen von factor vii polypeptiden |
| AU2004264282B2 (en) | 2003-08-14 | 2010-10-14 | Novo Nordisk Health Care Ag | Liquid, aqueous pharmaceutical composition of Factor VII polypeptides |
| PT2298287T (pt) | 2003-12-19 | 2018-07-23 | Novo Nordisk Healthcare Ag | Composições estabilizadas de polipéptidos de fator vii |
| US20080305518A1 (en) * | 2004-05-04 | 2008-12-11 | Novo Nordisk Healthcare A/G | O-Linked Glycoforms Of Polypeptides And Method To Manufacture Them |
| US20070037966A1 (en) * | 2004-05-04 | 2007-02-15 | Novo Nordisk A/S | Hydrophobic interaction chromatography purification of factor VII polypeptides |
| WO2006014839A2 (fr) * | 2004-07-23 | 2006-02-09 | The University Of Rochester | La proteine c activee inhibe les effets secondaires de l'activateur de plasminogene dans le cerveau |
| WO2006035058A2 (fr) * | 2004-09-29 | 2006-04-06 | Novo Nordisk Health Care Ag | Purification d'une substance medicamenteuse faite d'un polypeptide facteur vii par suppression des structures polypeptides facteurs vii du desgla |
| PT1907540E (pt) * | 2005-07-22 | 2013-02-04 | Bayer Healthcare Llc | Activação do factor vii em solução |
| US7807435B2 (en) * | 2005-08-11 | 2010-10-05 | Baxter International Inc. | Method for the purification of alpha-1 proteinase inhibitor (a1PI) |
| ES2257225B1 (es) * | 2006-02-17 | 2007-03-16 | Grifols, S.A | Preparacion terapeutica de fviia de muy alta pureza y metodo para su obtencion. |
| TWI684599B (zh) * | 2014-08-12 | 2020-02-11 | 美商巴克斯歐塔公司 | 因子ｘ活化 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT154793B (de) | 1936-09-03 | 1938-10-25 | Telefunken Gmbh | Mehrgitterröhre. |
| AT350726B (de) * | 1976-08-30 | 1979-06-11 | Immuno Ag | Verfahren zur herstellung einer blut- gerinnungsfoerdernden praeperation aus menschlichem blutplasma |
| US4287180A (en) * | 1980-01-28 | 1981-09-01 | Baxter Travenol Laboratories, Inc. | Method for treating blood clotting factor inhibitors |
| EP0044343B1 (fr) * | 1980-01-28 | 1984-08-22 | Baxter Travenol Laboratories, Inc. | Compositions therapeutiques contenant de la prothrombine et procede de production de facteurs de coagulation du sang agissant enzymatiquement, a partir de fractions sanguines contenant de la prothrombine |
| US4364861A (en) * | 1980-05-27 | 1982-12-21 | Cutter Laboratories, Inc. | Blood-coagulation-promoting products and methods of preparing them |
| AT368883B (de) * | 1980-07-22 | 1982-11-25 | Immuno Ag | Verfahren zur herstellung einer neuen blutgerinnungsfoerdernden praeparation auf basis von humanproteinen |
| US4382083A (en) * | 1981-06-25 | 1983-05-03 | Baxter Travenol Laboratories, Inc. | Therapeutic method for treating blood-clotting defects with factor VIIa |
| DE3473407D1 (en) * | 1983-05-02 | 1988-09-22 | Immuno Ag | Method of inactivating pathogens |
| AT389815B (de) * | 1984-03-09 | 1990-02-12 | Immuno Ag | Verfahren zur inaktivierung von vermehrungsfaehigen filtrierbaren krankheitserregern in blutprodukten |
| DE3740520A1 (de) * | 1987-11-30 | 1989-06-08 | Hans Dr Rer Nat Scheefers | Schnelles verfahren zur gewinnung einer faktor vii - praeparation sowie ihre verwendung |
| FR2632524B1 (fr) * | 1988-06-09 | 1992-03-13 | Fondation Nale Transfusion San | Procede de preparation d'une fraction concentree en facteur viia et son application a titre de medicament |
| US5472850A (en) * | 1991-04-10 | 1995-12-05 | Oklahoma Medical Research Foundation | Quantitative clotting assay for activated factor VII |
| DE69023829T2 (de) * | 1989-08-04 | 1996-07-04 | Komori Printing Mach | Druckplattebefestigung für eine Bogendruckmaschine. |
| AT402891B (de) * | 1991-06-20 | 1997-09-25 | Immuno Ag | Verfahren zur herstellung eines inaktivierten blutproduktes |
| FR2684999A1 (fr) * | 1991-12-16 | 1993-06-18 | Aquitaine Dev Transf Sanguine | Procede de fabrication d'un concentre de facteur vii active de haute purete essentiellement depourvu des facteurs vitamine k dependants et des facteurs viiic et viiicag. |
| AT402151B (de) * | 1993-08-03 | 1997-02-25 | Immuno Ag | Verfahren zur herstellung eines virussicheren biologischen präparates |
-
1995
- 1995-08-28 DE DE19531637A patent/DE19531637A1/de not_active Withdrawn
-
1996
- 1996-07-09 EP EP96111052A patent/EP0765669A1/fr not_active Withdrawn
- 1996-08-22 US US08/701,755 patent/US5891843A/en not_active Expired - Lifetime
- 1996-08-27 NO NO963568A patent/NO963568L/no not_active Application Discontinuation
- 1996-08-27 CA CA002184226A patent/CA2184226A1/fr not_active Abandoned
- 1996-08-28 JP JP8226561A patent/JPH09110715A/ja active Pending
-
1997
- 1997-09-11 US US08/926,845 patent/US6013620A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US6013620A (en) | 2000-01-11 |
| DE19531637A1 (de) | 1997-03-06 |
| EP0765669A1 (fr) | 1997-04-02 |
| CA2184226A1 (fr) | 1997-03-01 |
| US5891843A (en) | 1999-04-06 |
| JPH09110715A (ja) | 1997-04-28 |
| NO963568D0 (no) | 1996-08-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FC2A | Withdrawal, rejection or dismissal of laid open patent application |