NO963066D0 - Substituerte 3-aryliden-7-azaoksindolforbindelser og fremgangsmåte for deres fremstilling - Google Patents
Substituerte 3-aryliden-7-azaoksindolforbindelser og fremgangsmåte for deres fremstillingInfo
- Publication number
- NO963066D0 NO963066D0 NO963066A NO963066A NO963066D0 NO 963066 D0 NO963066 D0 NO 963066D0 NO 963066 A NO963066 A NO 963066A NO 963066 A NO963066 A NO 963066A NO 963066 D0 NO963066 D0 NO 963066D0
- Authority
- NO
- Norway
- Prior art keywords
- nch2oh
- choh
- alkyl
- image
- pct
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9423997A GB9423997D0 (en) | 1994-11-28 | 1994-11-28 | Substituted 3-arylidene-7-azaoxindole compounds and process for their preparation |
PCT/EP1995/004247 WO1996016964A1 (en) | 1994-11-28 | 1995-10-30 | Substituted 3-arylidene-7-azaoxindole compounds and process for their preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
NO963066D0 true NO963066D0 (no) | 1996-07-23 |
NO963066L NO963066L (no) | 1996-07-23 |
Family
ID=10765093
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO963066A NO963066L (no) | 1994-11-28 | 1996-07-23 | Substituerte 3-aryliden-7-azaoksindolforbindelser og fremgangsmåte for deres fremstilling |
Country Status (22)
Country | Link |
---|---|
US (1) | US5719135A (no) |
EP (1) | EP0741726B1 (no) |
JP (1) | JPH09508924A (no) |
CN (1) | CN1139929A (no) |
AT (1) | ATE186727T1 (no) |
AU (1) | AU3926295A (no) |
CA (1) | CA2180730C (no) |
DE (1) | DE69513383T2 (no) |
DK (1) | DK0741726T3 (no) |
ES (1) | ES2140717T3 (no) |
FI (1) | FI962954A (no) |
GB (1) | GB9423997D0 (no) |
GR (1) | GR3032535T3 (no) |
HU (1) | HUT74875A (no) |
IL (1) | IL116002A0 (no) |
MX (1) | MX9602838A (no) |
NO (1) | NO963066L (no) |
NZ (1) | NZ295668A (no) |
PL (1) | PL315689A1 (no) |
PT (1) | PT741726E (no) |
WO (1) | WO1996016964A1 (no) |
ZA (1) | ZA959927B (no) |
Families Citing this family (46)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6147106A (en) | 1997-08-20 | 2000-11-14 | Sugen, Inc. | Indolinone combinatorial libraries and related products and methods for the treatment of disease |
US6316635B1 (en) | 1995-06-07 | 2001-11-13 | Sugen, Inc. | 2-indolinone derivatives as modulators of protein kinase activity |
US5880141A (en) * | 1995-06-07 | 1999-03-09 | Sugen, Inc. | Benzylidene-Z-indoline compounds for the treatment of disease |
US6906093B2 (en) | 1995-06-07 | 2005-06-14 | Sugen, Inc. | Indolinone combinatorial libraries and related products and methods for the treatment of disease |
GB9610964D0 (en) * | 1996-05-24 | 1996-07-31 | Pharmacia & Upjohn Spa | Substituted tetralylmethylen-oxindole analogues as tyrosine kinase inhibitors |
GB9611797D0 (en) * | 1996-06-06 | 1996-08-07 | Pharmacia Spa | Substituted quinolylmethylen-oxindole analogues as tyrosine kinase inhibitors |
GB9613021D0 (en) * | 1996-06-21 | 1996-08-28 | Pharmacia Spa | Bicyclic 4-aralkylaminopyrimidine derivatives as tyrosine kinase inhibitors |
US6316429B1 (en) | 1997-05-07 | 2001-11-13 | Sugen, Inc. | Bicyclic protein kinase inhibitors |
US6486185B1 (en) | 1997-05-07 | 2002-11-26 | Sugen, Inc. | 3-heteroarylidene-2-indolinone protein kinase inhibitors |
US6987113B2 (en) * | 1997-06-11 | 2006-01-17 | Sugen, Inc. | Tyrosine kinase inhibitors |
GB9718913D0 (en) | 1997-09-05 | 1997-11-12 | Glaxo Group Ltd | Substituted oxindole derivatives |
GB9721437D0 (en) * | 1997-10-10 | 1997-12-10 | Glaxo Group Ltd | Heteroaromatic compounds and their use in medicine |
US6531502B1 (en) | 1998-01-21 | 2003-03-11 | Sugen, Inc. | 3-Methylidenyl-2-indolinone modulators of protein kinase |
EP1066257A2 (en) * | 1998-03-26 | 2001-01-10 | Sugen, Inc. | Heterocylic classes of compounds for the modulating tyrosine protein kinase |
US6514981B1 (en) | 1998-04-02 | 2003-02-04 | Sugen, Inc. | Methods of modulating tyrosine protein kinase function with indolinone compounds |
US6569868B2 (en) | 1998-04-16 | 2003-05-27 | Sugen, Inc. | 2-indolinone derivatives as modulators of protein kinase activity |
CA2314156C (en) | 1998-05-29 | 2010-05-25 | Sugen, Inc. | Pyrrole substituted 2-indolinone protein kinase inhibitors |
CA2342251A1 (en) | 1998-08-28 | 2000-03-09 | Scios Inc. | Use of piperidines and/or piperazines as inhibitors of p38-alpha kinase |
US6153634A (en) | 1998-12-17 | 2000-11-28 | Hoffmann-La Roche Inc. | 4,5-azolo-oxindoles |
TR200101860T2 (tr) | 1998-12-17 | 2001-12-21 | F.Hoffmann-La Roche Ag | Sikline bağlı kinaz inhibitörleri olarak 4-alkenil (ve alkinil) oksidoller |
CN1158283C (zh) | 1998-12-17 | 2004-07-21 | 霍夫曼-拉罗奇有限公司 | 作为蛋白激酶抑制剂的4-和5-吡嗪基羟吲哚 |
AU760039B2 (en) | 1998-12-17 | 2003-05-08 | F. Hoffmann-La Roche Ag | 4-aryloxindoles as inhibitors of JNK protein kinases |
US6492398B1 (en) | 1999-03-04 | 2002-12-10 | Smithkline Beechman Corporation | Thiazoloindolinone compounds |
US6624171B1 (en) | 1999-03-04 | 2003-09-23 | Smithkline Beecham Corporation | Substituted aza-oxindole derivatives |
GB9904933D0 (en) | 1999-03-04 | 1999-04-28 | Glaxo Group Ltd | Compounds |
US6689806B1 (en) | 1999-03-24 | 2004-02-10 | Sugen, Inc. | Indolinone compounds as kinase inhibitors |
US6541477B2 (en) | 1999-08-27 | 2003-04-01 | Scios, Inc. | Inhibitors of p38-a kinase |
US6878733B1 (en) | 1999-11-24 | 2005-04-12 | Sugen, Inc. | Formulations for pharmaceutical agents ionizable as free acids or free bases |
US6313310B1 (en) | 1999-12-15 | 2001-11-06 | Hoffmann-La Roche Inc. | 4-and 5-alkynyloxindoles and 4-and 5-alkenyloxindoles |
WO2001046196A1 (en) * | 1999-12-21 | 2001-06-28 | Sugen, Inc. | 4-substituted 7-aza-indolin-2-ones and their use as protein kinase inhibitors |
US6620818B1 (en) | 2000-03-01 | 2003-09-16 | Smithkline Beecham Corporation | Method for reducing the severity of side effects of chemotherapy and/or radiation therapy |
TWI270545B (en) | 2000-05-24 | 2007-01-11 | Sugen Inc | Mannich base prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives |
CA2410509A1 (en) | 2000-06-02 | 2001-12-13 | Sugen, Inc. | Indolinone derivatives as protein kinase/phosphatase inhibitors |
US6335342B1 (en) | 2000-06-19 | 2002-01-01 | Pharmacia & Upjohn S.P.A. | Azaindole derivatives, process for their preparation, and their use as antitumor agents |
DE60203260T2 (de) | 2001-01-16 | 2006-02-02 | Glaxo Group Ltd., Greenford | Pharmazeutische kombination, die ein 4-chinazolinamin und paclitaxel, carboplatin oder vinorelbin enthält, zur behandlung von krebs |
US6504034B2 (en) | 2001-01-23 | 2003-01-07 | Hoffmann-La Roche Inc. | Naphthostyrils |
JP2005508337A (ja) * | 2001-09-27 | 2005-03-31 | スミスクライン ビーチャム コーポレーション | 化合物 |
KR101452520B1 (ko) * | 2006-01-27 | 2014-10-21 | 샹하이 헨그루이 파마수티컬 컴퍼니 리미티드 | 피롤로[3,2-c]피리딘-4-온 2-인돌린온 단백질 키나제 억제제 |
CN101367801B (zh) * | 2007-08-15 | 2011-01-12 | 上海恒瑞医药有限公司 | 吡咯并六元n杂环羟基吗啡啉类衍生物的制备方法及其在医药上的应用 |
US8669363B2 (en) | 2011-03-24 | 2014-03-11 | Southern Methodist University | Quinoxaline compounds and derivatives |
US9493452B2 (en) * | 2011-03-24 | 2016-11-15 | Southern Methodist University | Compounds and derivatives of 2H-pyrido (3,2-b)(1, 4) oxazin 3)4H)-ones as raf kinase and LRRK2 inhibitors |
US9309208B2 (en) | 2012-03-23 | 2016-04-12 | Southern Methodist University | Methods of making and using thioxothiazolidine and rhodanine derivatives as HIV-1 and JSP-1 inhibitors |
CN103864784B (zh) * | 2014-02-28 | 2017-05-03 | 温州医科大学 | 一种新型氮杂吲哚‑2‑酮类fgfr1抑制剂及其抗肿瘤活性 |
WO2022006238A1 (en) * | 2020-07-01 | 2022-01-06 | Angion Biomedica Corp. | Solid forms of (z)-methyl 3-(((4-(n-methyl-2-(4-methylpiperazin-l- yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxo-2, 3-dihydro- lh-pyrrolo[2,3-b]pyridine-6-carboxylate and salts thereof |
EP4255422A1 (en) * | 2020-12-03 | 2023-10-11 | Mydecine Innovations Group Inc. | Novel psilocin analog compositions and methods of synthesizing the same |
WO2024071415A1 (ja) * | 2022-09-30 | 2024-04-04 | 日本ポリケム株式会社 | 化合物、金属錯体、オレフィン重合用触媒組成物、オレフィン重合用触媒、及び、オレフィン系重合体の製造方法 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9226855D0 (en) * | 1992-12-23 | 1993-02-17 | Erba Carlo Spa | Vinylene-azaindole derivatives and process for their preparation |
-
1994
- 1994-11-28 GB GB9423997A patent/GB9423997D0/en active Pending
-
1995
- 1995-10-30 EP EP95937030A patent/EP0741726B1/en not_active Expired - Lifetime
- 1995-10-30 MX MX9602838A patent/MX9602838A/es not_active Application Discontinuation
- 1995-10-30 PT PT95937030T patent/PT741726E/pt unknown
- 1995-10-30 DE DE69513383T patent/DE69513383T2/de not_active Expired - Fee Related
- 1995-10-30 JP JP8518113A patent/JPH09508924A/ja not_active Ceased
- 1995-10-30 AT AT95937030T patent/ATE186727T1/de not_active IP Right Cessation
- 1995-10-30 ES ES95937030T patent/ES2140717T3/es not_active Expired - Lifetime
- 1995-10-30 PL PL95315689A patent/PL315689A1/xx unknown
- 1995-10-30 WO PCT/EP1995/004247 patent/WO1996016964A1/en active IP Right Grant
- 1995-10-30 CN CN95191374A patent/CN1139929A/zh active Pending
- 1995-10-30 DK DK95937030T patent/DK0741726T3/da active
- 1995-10-30 NZ NZ295668A patent/NZ295668A/en unknown
- 1995-10-30 AU AU39262/95A patent/AU3926295A/en not_active Abandoned
- 1995-10-30 HU HU9602357A patent/HUT74875A/hu unknown
- 1995-10-30 US US08/669,315 patent/US5719135A/en not_active Expired - Fee Related
- 1995-10-30 CA CA002180730A patent/CA2180730C/en not_active Expired - Fee Related
- 1995-11-15 IL IL11600295A patent/IL116002A0/xx unknown
- 1995-11-22 ZA ZA959927A patent/ZA959927B/xx unknown
-
1996
- 1996-07-23 NO NO963066A patent/NO963066L/no unknown
- 1996-07-24 FI FI962954A patent/FI962954A/fi not_active Application Discontinuation
-
2000
- 2000-02-02 GR GR20000400231T patent/GR3032535T3/el not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2180730A1 (en) | 1996-06-06 |
MX9602838A (es) | 1997-06-28 |
NO963066L (no) | 1996-07-23 |
DE69513383D1 (de) | 1999-12-23 |
US5719135A (en) | 1998-02-17 |
ES2140717T3 (es) | 2000-03-01 |
PL315689A1 (en) | 1996-11-25 |
FI962954A0 (fi) | 1996-07-24 |
AU3926295A (en) | 1996-06-19 |
JPH09508924A (ja) | 1997-09-09 |
IL116002A0 (en) | 1996-01-31 |
FI962954A (fi) | 1996-07-24 |
WO1996016964A1 (en) | 1996-06-06 |
GR3032535T3 (en) | 2000-05-31 |
GB9423997D0 (en) | 1995-01-11 |
HUT74875A (en) | 1997-02-28 |
ATE186727T1 (de) | 1999-12-15 |
NZ295668A (en) | 1997-11-24 |
ZA959927B (en) | 1996-06-10 |
PT741726E (pt) | 2000-04-28 |
DE69513383T2 (de) | 2000-05-18 |
EP0741726B1 (en) | 1999-11-17 |
HU9602357D0 (en) | 1996-11-28 |
DK0741726T3 (da) | 2000-04-17 |
CN1139929A (zh) | 1997-01-08 |
CA2180730C (en) | 2006-09-12 |
EP0741726A1 (en) | 1996-11-13 |
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