NO962783L - thrombopoietin - Google Patents
thrombopoietinInfo
- Publication number
- NO962783L NO962783L NO962783A NO962783A NO962783L NO 962783 L NO962783 L NO 962783L NO 962783 A NO962783 A NO 962783A NO 962783 A NO962783 A NO 962783A NO 962783 L NO962783 L NO 962783L
- Authority
- NO
- Norway
- Prior art keywords
- thrombopoietin
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/524—Thrombopoietin, i.e. C-MPL ligand
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US17655394A | 1994-01-03 | 1994-01-03 | |
US18560794A | 1994-01-21 | 1994-01-21 | |
US08/196,689 US8357513B1 (en) | 1994-01-03 | 1994-02-15 | Nucleic acids encoding mpl ligand (thrombopoietin) and fragments thereof |
US22326394A | 1994-04-04 | 1994-04-04 | |
US08/249,376 US8192955B1 (en) | 1994-01-03 | 1994-05-25 | Nucleic acids encoding MPL ligand (thrombopoietin), variants, and fragments thereof |
US34865894A | 1994-12-02 | 1994-12-02 | |
US08/348,657 US6660256B1 (en) | 1994-01-03 | 1994-12-02 | Porcine mpl ligand |
PCT/US1994/014553 WO1995018858A1 (en) | 1994-01-03 | 1994-12-28 | Thrombopoietin |
Publications (3)
Publication Number | Publication Date |
---|---|
NO962783D0 NO962783D0 (en) | 1996-07-02 |
NO962783L true NO962783L (en) | 1996-09-03 |
NO326903B1 NO326903B1 (en) | 2009-03-16 |
Family
ID=27569151
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO19962783A NO326903B1 (en) | 1994-01-03 | 1996-07-02 | Isolated mpl ligand polypeptide, isolated nucleic acid molecule, expression vector, host cell, process for producing mpl ligand, antibody and pharmaceutical preparation for the treatment or prevention of thrombocytopenia. |
Country Status (28)
Country | Link |
---|---|
EP (1) | EP0738323A1 (en) |
JP (2) | JPH09508262A (en) |
CN (1) | CN1134539C (en) |
AU (1) | AU704266B2 (en) |
BG (1) | BG63639B1 (en) |
CA (1) | CA2178482C (en) |
CZ (1) | CZ296130B6 (en) |
DK (1) | DK149194A (en) |
ES (1) | ES2114786B1 (en) |
FI (1) | FI121573B (en) |
FR (1) | FR2714670B1 (en) |
GB (1) | GB2285446B (en) |
HR (1) | HRP941020A2 (en) |
HU (1) | HUT75657A (en) |
IE (1) | IE72517B1 (en) |
IL (1) | IL112184A (en) |
IT (1) | IT1283770B1 (en) |
LU (1) | LU88573A1 (en) |
LV (1) | LV11632B (en) |
NL (1) | NL9500010A (en) |
NO (1) | NO326903B1 (en) |
NZ (1) | NZ278726A (en) |
PT (1) | PT101627B (en) |
RO (1) | RO117110B1 (en) |
SG (1) | SG47030A1 (en) |
SI (1) | SI9420079A (en) |
SK (1) | SK282265B6 (en) |
WO (1) | WO1995018858A1 (en) |
Families Citing this family (54)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6270989B1 (en) * | 1991-11-05 | 2001-08-07 | Transkaryotic Therapies, Inc. | Protein production and delivery |
US5733761A (en) | 1991-11-05 | 1998-03-31 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
CZ288926B6 (en) * | 1994-03-31 | 2001-09-12 | Amgen Inc. | MGDF derivative, process of its preparation and pharmaceutical preparation in it is comprised |
US5795569A (en) * | 1994-03-31 | 1998-08-18 | Amgen Inc. | Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation |
US5986049A (en) * | 1994-12-30 | 1999-11-16 | Zymogenetics, Inc. | Purified thrombopoietin and method of making it |
TW387940B (en) * | 1995-01-17 | 2000-04-21 | Kirin Brewery | Anti-tpo monodonal antibody |
JPH11500308A (en) | 1995-02-03 | 1999-01-12 | ジー.ディー.サール アンド カンパニー | New c-MPL ligand |
US5696250A (en) | 1995-02-15 | 1997-12-09 | Amgen Inc. | DNA encoding megakaryocyte growth and development factor analogs |
ATE323724T1 (en) * | 1995-02-15 | 2006-05-15 | Amgen Inc | MPL LIGAND ANALOGUE |
US5989538A (en) * | 1995-02-15 | 1999-11-23 | Amgen Inc. | Mpl ligand analogs |
TW434020B (en) * | 1995-03-15 | 2001-05-16 | Kirin Brewery | Methods for preventing adsorption of thrombopoietin (TPO), and stable top-containing compositions |
TW434021B (en) * | 1995-03-15 | 2001-05-16 | Kirin Brewery | Methods for preventing adsorption of thrombopoietin (TPO), and stable TPO-containing compositions |
ZA964382B (en) * | 1995-06-06 | 1997-12-01 | Genentech Inc | Lymphotoxin and thrombopoietin for use in the treatment of cancer. |
US6251864B1 (en) | 1995-06-07 | 2001-06-26 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
US5869451A (en) * | 1995-06-07 | 1999-02-09 | Glaxo Group Limited | Peptides and compounds that bind to a receptor |
NZ310778A (en) * | 1995-06-07 | 1999-10-28 | Glaxo Group Ltd | Peptides and compounds that bind to a thrombopoietin receptor |
TW497972B (en) * | 1995-06-08 | 2002-08-11 | Kirin Brewery | Stable thrombopoietin (TPO)-containing lyophilized compositions |
US6066318A (en) * | 1995-10-05 | 2000-05-23 | G.D. Searle & Co. | Multi-functional hematopoietic fusion proteins between sequence rearranged C-MPL receptor agonists and other hematopoietic factors |
US6031071A (en) * | 1996-01-24 | 2000-02-29 | Biophage, Inc. | Methods of generating novel peptides |
US5879673A (en) * | 1996-01-25 | 1999-03-09 | Genentech, Inc. | Administration of thrombopoietin on a single day only |
US7091311B2 (en) | 1996-06-07 | 2006-08-15 | Smithkline Beecham Corporation | Peptides and compounds that bind to a receptor |
CN1230993A (en) * | 1996-08-13 | 1999-10-06 | 津莫吉尼蒂克斯公司 | Expression vectors, cells, and methods for preparing thrombopoietin polypeptides |
JP4562815B2 (en) * | 1997-05-21 | 2010-10-13 | ジェネンテック, インコーポレイテッド | New administration of thrombopoietin |
US5980893A (en) * | 1997-07-17 | 1999-11-09 | Beth Israel Deaconess Medical Center, Inc. | Agonist murine monoclonal antibody as a stimulant for megakaryocytopoiesis |
US6342220B1 (en) | 1997-08-25 | 2002-01-29 | Genentech, Inc. | Agonist antibodies |
US20030228666A1 (en) | 1998-06-30 | 2003-12-11 | Daewoong Pharmaceutical Co., Ltd. | Novel human thrombopoietin mutein |
KR20000006549A (en) * | 1998-06-30 | 2000-01-25 | 윤재승 | A novel human thrombopoietin mutein |
US6660843B1 (en) | 1998-10-23 | 2003-12-09 | Amgen Inc. | Modified peptides as therapeutic agents |
KR100719202B1 (en) | 1998-10-23 | 2007-05-16 | 키린-암젠 인코포레이티드 | A COMPOUND BINDING TO MPl RECEPTOR AND A PHARMACEUTICAL COMPOSITION THEREOF |
CY2010012I2 (en) * | 2000-05-25 | 2020-05-29 | Novartis Ag | THROMBOPOIETIN MIMETICS |
UY26317A1 (en) * | 2000-08-30 | 2000-10-31 | Alfonso Cayota Carlos Pritsch | PRODUCTION SYSTEM OF HUMAN THROMBOPOYETINE BY CELLS OF MAMMALS IN CULTIVATION |
US6673580B2 (en) | 2000-10-27 | 2004-01-06 | Genentech, Inc. | Identification and modification of immunodominant epitopes in polypeptides |
US7332474B2 (en) | 2001-10-11 | 2008-02-19 | Amgen Inc. | Peptides and related compounds having thrombopoietic activity |
US20050177884A1 (en) | 2001-11-15 | 2005-08-11 | Kirin Beer Kabushiki Kaisha | Chimeric nonhuman animal |
KR100467750B1 (en) * | 2001-11-29 | 2005-01-24 | 씨제이 주식회사 | Fusion protein having the enhanced in vivo activity of erythropoietin |
US20030191056A1 (en) | 2002-04-04 | 2003-10-09 | Kenneth Walker | Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins |
ES2781475T3 (en) | 2002-09-18 | 2020-09-02 | Janssen Pharmaceuticals Inc | Methods to increase the production of hematopoietic stem cells and platelets |
DK1675606T3 (en) | 2003-08-28 | 2017-06-19 | Janssen Pharmaceuticals Inc | Peptides and compound that bind to thrombopoietin receptors |
US7723295B2 (en) | 2003-08-28 | 2010-05-25 | Ortho-Mcneil Pharmaceutical, Inc. | Peptides and compounds that bind to a receptor |
EP2484772B1 (en) * | 2004-05-18 | 2016-08-17 | Intrexon Corporation | Methods for dynamic vector assembly of DNA cloning vector plasmids |
US8143380B2 (en) | 2004-07-08 | 2012-03-27 | Amgen Inc. | Therapeutic peptides |
US8008453B2 (en) | 2005-08-12 | 2011-08-30 | Amgen Inc. | Modified Fc molecules |
US9012605B2 (en) | 2006-01-23 | 2015-04-21 | Amgen Inc. | Crystalline polypeptides |
WO2007098547A1 (en) * | 2006-03-01 | 2007-09-07 | Apollo Life Sciences Limited | A molecule and chimeric molecules thereof |
US7981425B2 (en) | 2006-06-19 | 2011-07-19 | Amgen Inc. | Thrombopoietic compounds |
EP2044197B8 (en) | 2006-07-24 | 2018-03-07 | The University Of Queensland | Method of producing a population of cells |
WO2008153745A2 (en) | 2007-05-22 | 2008-12-18 | Amgen Inc. | Compositions and methods for producing bioactive fusion proteins |
US20110294733A1 (en) | 2009-01-20 | 2011-12-01 | Hanall Biopharma Co., Ltd. | Modified human thrombopoietin polypeptide fragment and manufacturing method thereof |
WO2014089478A1 (en) * | 2012-12-07 | 2014-06-12 | University Of Tennessee Research Foundation | Methods of numerical analysis for platelet disorders and computer-readable media and systems for performing the same |
CA2896053A1 (en) * | 2012-12-21 | 2014-06-26 | Ocata Therapeutics, Inc. | Methods for production of platelets from pluripotent stem cells and compositions thereof |
CN103555760B (en) * | 2013-10-18 | 2015-05-20 | 江苏康禾生物制药有限公司 | Preparation method and preparation of recombinant human thrombopoietin |
GB201700621D0 (en) | 2017-01-13 | 2017-03-01 | Guest Ryan Dominic | Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue |
WO2021052470A1 (en) * | 2019-09-20 | 2021-03-25 | 中美瑞康核酸技术(南通)研究院有限公司 | Nucleic acid molecule for treating immune thrombocytopenia and application thereof |
AU2020408017A1 (en) | 2019-12-20 | 2022-07-14 | Instil Bio (Uk) Limited | Devices and methods for isolating tumor infiltrating lymphocytes and uses thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5260417A (en) | 1989-04-03 | 1993-11-09 | Genetics Institute, Inc. | Megakaryocyte growth promoting activity protein |
AU5355790A (en) * | 1989-04-19 | 1990-11-16 | Cetus Corporation | Multifunctional m-csf proteins and genes encoding therefor |
US5223408A (en) * | 1991-07-11 | 1993-06-29 | Genentech, Inc. | Method for making variant secreted proteins with altered properties |
ES2160591T3 (en) * | 1991-12-06 | 2001-11-16 | Genentech Inc | CELLS TRANSFORMED BY PROHORMONAL CONVERTS. |
IL139335A (en) | 1994-01-03 | 2005-08-31 | Genentech Inc | Mpl ligand polypeptides, nucleic acids encoding them, vectors and host cells comprising such nucleic acids, processes for producing such polypeptides pharmaceutical compositions containing them and use thereof in the preparation of medicaments for treating thrombocytopenia |
-
1994
- 1994-12-21 GB GB9425831A patent/GB2285446B/en not_active Expired - Lifetime
- 1994-12-21 SG SG1996003050A patent/SG47030A1/en unknown
- 1994-12-27 HR HR08/348,658A patent/HRP941020A2/en not_active Application Discontinuation
- 1994-12-28 WO PCT/US1994/014553 patent/WO1995018858A1/en active IP Right Grant
- 1994-12-28 RO RO96-01347A patent/RO117110B1/en unknown
- 1994-12-28 CN CNB941947513A patent/CN1134539C/en not_active Expired - Lifetime
- 1994-12-28 JP JP7518499A patent/JPH09508262A/en active Pending
- 1994-12-28 AU AU15146/95A patent/AU704266B2/en not_active Expired
- 1994-12-28 CA CA2178482A patent/CA2178482C/en not_active Expired - Lifetime
- 1994-12-28 SI SI9420079A patent/SI9420079A/en unknown
- 1994-12-28 CZ CZ0192296A patent/CZ296130B6/en not_active IP Right Cessation
- 1994-12-28 HU HU9601805A patent/HUT75657A/en not_active Application Discontinuation
- 1994-12-28 EP EP95906653A patent/EP0738323A1/en not_active Withdrawn
- 1994-12-28 DK DK149194A patent/DK149194A/en not_active Application Discontinuation
- 1994-12-28 NZ NZ278726A patent/NZ278726A/en not_active IP Right Cessation
- 1994-12-28 SK SK875-96A patent/SK282265B6/en not_active IP Right Cessation
- 1994-12-29 IL IL11218494A patent/IL112184A/en not_active IP Right Cessation
- 1994-12-30 PT PT101627A patent/PT101627B/en not_active IP Right Cessation
- 1994-12-30 ES ES09402681A patent/ES2114786B1/en not_active Expired - Fee Related
-
1995
- 1995-01-02 IT IT95TO000002A patent/IT1283770B1/en active IP Right Grant
- 1995-01-02 FR FR9500007A patent/FR2714670B1/en not_active Expired - Lifetime
- 1995-01-03 LU LU88573A patent/LU88573A1/en unknown
- 1995-01-03 NL NL9500010A patent/NL9500010A/en active Search and Examination
- 1995-01-03 IE IE950002A patent/IE72517B1/en not_active IP Right Cessation
-
1996
- 1996-07-02 FI FI962723A patent/FI121573B/en not_active IP Right Cessation
- 1996-07-02 NO NO19962783A patent/NO326903B1/en not_active IP Right Cessation
- 1996-07-02 BG BG100693A patent/BG63639B1/en unknown
- 1996-07-24 LV LVP-96-315A patent/LV11632B/en unknown
-
1997
- 1997-03-27 JP JP9074906A patent/JPH10113186A/en active Pending
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MK1K | Patent expired |