FI962723A0 - thrombopoietin - Google Patents

thrombopoietin

Info

Publication number
FI962723A0
FI962723A0 FI962723A FI962723A FI962723A0 FI 962723 A0 FI962723 A0 FI 962723A0 FI 962723 A FI962723 A FI 962723A FI 962723 A FI962723 A FI 962723A FI 962723 A0 FI962723 A0 FI 962723A0
Authority
FI
Finland
Prior art keywords
thrombopoietin
Prior art date
Application number
FI962723A
Other languages
Finnish (fi)
Swedish (sv)
Other versions
FI121573B (en
FI962723A (en
Inventor
Dan L Eaton
Sauvage Frederic J De
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/196,689 external-priority patent/US8357513B1/en
Priority claimed from US08/249,376 external-priority patent/US8192955B1/en
Priority claimed from US08/348,657 external-priority patent/US6660256B1/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of FI962723A0 publication Critical patent/FI962723A0/en
Publication of FI962723A publication Critical patent/FI962723A/en
Application granted granted Critical
Publication of FI121573B publication Critical patent/FI121573B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/524—Thrombopoietin, i.e. C-MPL ligand
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Vehicle Body Suspensions (AREA)
  • Information Transfer Systems (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FI962723A 1994-01-03 1996-07-02 A method for preparing an isolated mpl ligand polypeptide FI121573B (en)

Applications Claiming Priority (16)

Application Number Priority Date Filing Date Title
US17655394A 1994-01-03 1994-01-03
US17655394 1994-01-03
US18560794A 1994-01-21 1994-01-21
US18560794 1994-01-21
US08/196,689 US8357513B1 (en) 1994-01-03 1994-02-15 Nucleic acids encoding mpl ligand (thrombopoietin) and fragments thereof
US19668994 1994-02-15
US22326394A 1994-04-04 1994-04-04
US22326394 1994-04-04
US24937694 1994-05-25
US08/249,376 US8192955B1 (en) 1994-01-03 1994-05-25 Nucleic acids encoding MPL ligand (thrombopoietin), variants, and fragments thereof
US34865894A 1994-12-02 1994-12-02
US34865894 1994-12-02
US08/348,657 US6660256B1 (en) 1994-01-03 1994-12-02 Porcine mpl ligand
US34865794 1994-12-02
PCT/US1994/014553 WO1995018858A1 (en) 1994-01-03 1994-12-28 Thrombopoietin
US9414553 1994-12-28

Publications (3)

Publication Number Publication Date
FI962723A0 true FI962723A0 (en) 1996-07-02
FI962723A FI962723A (en) 1996-09-03
FI121573B FI121573B (en) 2011-01-14

Family

ID=27569151

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962723A FI121573B (en) 1994-01-03 1996-07-02 A method for preparing an isolated mpl ligand polypeptide

Country Status (28)

Country Link
EP (1) EP0738323A1 (en)
JP (2) JPH09508262A (en)
CN (1) CN1134539C (en)
AU (1) AU704266B2 (en)
BG (1) BG63639B1 (en)
CA (1) CA2178482C (en)
CZ (1) CZ296130B6 (en)
DK (1) DK149194A (en)
ES (1) ES2114786B1 (en)
FI (1) FI121573B (en)
FR (1) FR2714670B1 (en)
GB (1) GB2285446B (en)
HR (1) HRP941020A2 (en)
HU (1) HUT75657A (en)
IE (1) IE72517B1 (en)
IL (1) IL112184A (en)
IT (1) IT1283770B1 (en)
LU (1) LU88573A1 (en)
LV (1) LV11632B (en)
NL (1) NL9500010A (en)
NO (1) NO326903B1 (en)
NZ (1) NZ278726A (en)
PT (1) PT101627B (en)
RO (1) RO117110B1 (en)
SG (1) SG47030A1 (en)
SI (1) SI9420079A (en)
SK (1) SK282265B6 (en)
WO (1) WO1995018858A1 (en)

Families Citing this family (56)

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US5733761A (en) 1991-11-05 1998-03-31 Transkaryotic Therapies, Inc. Protein production and protein delivery
US6270989B1 (en) 1991-11-05 2001-08-07 Transkaryotic Therapies, Inc. Protein production and delivery
US5795569A (en) * 1994-03-31 1998-08-18 Amgen Inc. Mono-pegylated proteins that stimulate megakaryocyte growth and differentiation
EP0755263A4 (en) * 1994-03-31 2005-02-09 Amgen Inc Compositions and methods for stimulating megakaryocyte growth and differentiation
US5986049A (en) * 1994-12-30 1999-11-16 Zymogenetics, Inc. Purified thrombopoietin and method of making it
TW387940B (en) * 1995-01-17 2000-04-21 Kirin Brewery Anti-tpo monodonal antibody
CA2212006A1 (en) 1995-02-03 1996-08-08 G.D. Searle & Co. Novel c-mpl ligands
AU691410B2 (en) * 1995-02-15 1998-05-14 Amgen, Inc. MPL ligand analogs
US5989538A (en) * 1995-02-15 1999-11-23 Amgen Inc. Mpl ligand analogs
US5696250A (en) * 1995-02-15 1997-12-09 Amgen Inc. DNA encoding megakaryocyte growth and development factor analogs
TW434020B (en) * 1995-03-15 2001-05-16 Kirin Brewery Methods for preventing adsorption of thrombopoietin (TPO), and stable top-containing compositions
TW434021B (en) * 1995-03-15 2001-05-16 Kirin Brewery Methods for preventing adsorption of thrombopoietin (TPO), and stable TPO-containing compositions
ZA964382B (en) * 1995-06-06 1997-12-01 Genentech Inc Lymphotoxin and thrombopoietin for use in the treatment of cancer.
US5869451A (en) * 1995-06-07 1999-02-09 Glaxo Group Limited Peptides and compounds that bind to a receptor
US6251864B1 (en) 1995-06-07 2001-06-26 Glaxo Group Limited Peptides and compounds that bind to a receptor
CN1315870C (en) 1995-06-07 2007-05-16 葛兰素集团有限公司 Peptide and compounds that bind to receptor
TW497972B (en) * 1995-06-08 2002-08-11 Kirin Brewery Stable thrombopoietin (TPO)-containing lyophilized compositions
US6066318A (en) * 1995-10-05 2000-05-23 G.D. Searle & Co. Multi-functional hematopoietic fusion proteins between sequence rearranged C-MPL receptor agonists and other hematopoietic factors
US6031071A (en) * 1996-01-24 2000-02-29 Biophage, Inc. Methods of generating novel peptides
US5879673A (en) * 1996-01-25 1999-03-09 Genentech, Inc. Administration of thrombopoietin on a single day only
US7091311B2 (en) 1996-06-07 2006-08-15 Smithkline Beecham Corporation Peptides and compounds that bind to a receptor
KR20000029998A (en) * 1996-08-13 2000-05-25 리스 데브라 케이. Expression vectors, cells, and methods for preparing thrombopoietin
EP0983082A1 (en) * 1997-05-21 2000-03-08 Genentech, Inc. Novel administration of thrombopoietin
US5980893A (en) * 1997-07-17 1999-11-09 Beth Israel Deaconess Medical Center, Inc. Agonist murine monoclonal antibody as a stimulant for megakaryocytopoiesis
US6342220B1 (en) 1997-08-25 2002-01-29 Genentech, Inc. Agonist antibodies
KR20000006549A (en) * 1998-06-30 2000-01-25 윤재승 A novel human thrombopoietin mutein
US20030228666A1 (en) 1998-06-30 2003-12-11 Daewoong Pharmaceutical Co., Ltd. Novel human thrombopoietin mutein
HU228582B1 (en) 1998-10-23 2013-04-29 Kirin Amgen Inc Dimeric thrombopoietin peptide mimetics binding to mp1 receptor and having thrombopoietic activity
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
CY2010012I2 (en) * 2000-05-25 2020-05-29 Novartis Ag THROMBOPOIETIN MIMETICS
UY26317A1 (en) * 2000-08-30 2000-10-31 Alfonso Cayota Carlos Pritsch PRODUCTION SYSTEM OF HUMAN THROMBOPOYETINE BY CELLS OF MAMMALS IN CULTIVATION
US6673580B2 (en) 2000-10-27 2004-01-06 Genentech, Inc. Identification and modification of immunodominant epitopes in polypeptides
US7332474B2 (en) 2001-10-11 2008-02-19 Amgen Inc. Peptides and related compounds having thrombopoietic activity
EP1994824A1 (en) 2001-11-15 2008-11-26 Kirin Pharma Kabushiki Kaisha Chimeric non-human animal
KR100467750B1 (en) * 2001-11-29 2005-01-24 씨제이 주식회사 Fusion protein having the enhanced in vivo activity of erythropoietin
US20030191056A1 (en) 2002-04-04 2003-10-09 Kenneth Walker Use of transthyretin peptide/protein fusions to increase the serum half-life of pharmacologically active peptides/proteins
ES2462916T3 (en) 2002-09-18 2014-05-26 Janssen Pharmaceuticals, Inc. Methods to increase the production of hematopoietic stem cells and platelets
SI1675606T1 (en) 2003-08-28 2017-07-31 Janssen Pharmaceuticals, Inc. Peptides and compounds that bind to thrombopoietin receptors
US7723295B2 (en) 2003-08-28 2010-05-25 Ortho-Mcneil Pharmaceutical, Inc. Peptides and compounds that bind to a receptor
NZ583974A (en) 2004-05-18 2011-11-25 Intrexon Corp Methods for dynamic vector assembly of DNA cloning vector plasmids
US8143380B2 (en) 2004-07-08 2012-03-27 Amgen Inc. Therapeutic peptides
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
US9012605B2 (en) 2006-01-23 2015-04-21 Amgen Inc. Crystalline polypeptides
WO2007098547A1 (en) * 2006-03-01 2007-09-07 Apollo Life Sciences Limited A molecule and chimeric molecules thereof
US7981425B2 (en) 2006-06-19 2011-07-19 Amgen Inc. Thrombopoietic compounds
JP5543778B2 (en) 2006-07-24 2014-07-09 ザ・ユニバーシティ・オブ・クイーンズランド Methods for producing cell populations
TW200902708A (en) 2007-04-23 2009-01-16 Wyeth Corp Methods of protein production using anti-senescence compounds
CA2687141C (en) 2007-05-22 2014-04-01 Amgen Inc. Compositions and methods for producing bioactive fusion proteins
US20110294733A1 (en) 2009-01-20 2011-12-01 Hanall Biopharma Co., Ltd. Modified human thrombopoietin polypeptide fragment and manufacturing method thereof
WO2014089478A1 (en) * 2012-12-07 2014-06-12 University Of Tennessee Research Foundation Methods of numerical analysis for platelet disorders and computer-readable media and systems for performing the same
CA2896053A1 (en) 2012-12-21 2014-06-26 Ocata Therapeutics, Inc. Methods for production of platelets from pluripotent stem cells and compositions thereof
CN103555760B (en) * 2013-10-18 2015-05-20 江苏康禾生物制药有限公司 Preparation method and preparation of recombinant human thrombopoietin
RU2694064C1 (en) * 2015-12-21 2019-07-09 Браинон Инк. Composition for memory improvement, learning and cognitive abilities
GB201700621D0 (en) 2017-01-13 2017-03-01 Guest Ryan Dominic Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue
PE20220604A1 (en) * 2019-09-20 2022-04-25 Ractigen Therapeutics NUCLEIC ACID MOLECULE FOR THE TREATMENT OF THROMBOCYTOPENIA AND USE THEREOF
CA3164986A1 (en) 2019-12-20 2021-06-24 Instil Bio (Uk) Limited Devices and methods for isolating tumor infiltrating lymphocytes and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5260417A (en) 1989-04-03 1993-11-09 Genetics Institute, Inc. Megakaryocyte growth promoting activity protein
AU5355790A (en) * 1989-04-19 1990-11-16 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
US5223408A (en) * 1991-07-11 1993-06-29 Genentech, Inc. Method for making variant secreted proteins with altered properties
ATE204606T1 (en) * 1991-12-06 2001-09-15 Genentech Inc PROHORMONE CONVERTASE TRANSFORMED CELLS.
IL139335A (en) 1994-01-03 2005-08-31 Genentech Inc Mpl ligand polypeptides, nucleic acids encoding them, vectors and host cells comprising such nucleic acids, processes for producing such polypeptides pharmaceutical compositions containing them and use thereof in the preparation of medicaments for treating thrombocytopenia

Also Published As

Publication number Publication date
SI9420079A (en) 1997-02-28
IL112184A (en) 2004-07-25
GB9425831D0 (en) 1995-02-22
GB2285446B (en) 1999-07-28
CZ192296A3 (en) 1997-05-14
FR2714670A1 (en) 1995-07-07
FR2714670B1 (en) 1997-01-10
IT1283770B1 (en) 1998-04-30
ITTO950002A0 (en) 1995-01-02
FI121573B (en) 2011-01-14
HRP941020A2 (en) 1997-04-30
GB2285446A (en) 1995-07-12
JPH09508262A (en) 1997-08-26
CZ296130B6 (en) 2006-01-11
CN1134539C (en) 2004-01-14
ES2114786B1 (en) 1999-01-01
LU88573A1 (en) 1995-06-01
ES2114786A1 (en) 1998-06-01
EP0738323A1 (en) 1996-10-23
NO962783L (en) 1996-09-03
SK87596A3 (en) 1997-11-05
JPH10113186A (en) 1998-05-06
FI962723A (en) 1996-09-03
PT101627A (en) 1995-11-30
BG63639B1 (en) 2002-07-31
HUT75657A (en) 1997-05-28
IE950002A1 (en) 1995-07-12
ITTO950002A1 (en) 1995-07-03
LV11632B (en) 1997-04-20
CA2178482A1 (en) 1995-07-13
CN1141061A (en) 1997-01-22
SK282265B6 (en) 2001-12-03
IE72517B1 (en) 1997-04-23
NZ278726A (en) 1998-06-26
SG47030A1 (en) 1998-03-20
RO117110B1 (en) 2001-10-30
BG100693A (en) 1998-01-30
AU704266B2 (en) 1999-04-15
WO1995018858A1 (en) 1995-07-13
NO326903B1 (en) 2009-03-16
PT101627B (en) 1996-11-29
IL112184A0 (en) 1995-03-15
NO962783D0 (en) 1996-07-02
CA2178482C (en) 2012-01-03
AU1514695A (en) 1995-08-01
LV11632A (en) 1996-12-20
HU9601805D0 (en) 1996-08-28
NL9500010A (en) 1995-08-01
DK149194A (en) 1995-07-04

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