NO954485L - Intravenös opplösning for et staurosporinderivat - Google Patents

Intravenös opplösning for et staurosporinderivat

Info

Publication number
NO954485L
NO954485L NO954485A NO954485A NO954485L NO 954485 L NO954485 L NO 954485L NO 954485 A NO954485 A NO 954485A NO 954485 A NO954485 A NO 954485A NO 954485 L NO954485 L NO 954485L
Authority
NO
Norway
Prior art keywords
intravenous solution
staurosporine derivative
administration
staurosporin
mode
Prior art date
Application number
NO954485A
Other languages
English (en)
Other versions
NO954485D0 (no
Inventor
Hans Georg Weder
Ute Isele
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of NO954485D0 publication Critical patent/NO954485D0/no
Publication of NO954485L publication Critical patent/NO954485L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/553Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/107Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

En ny, fordelaktig administreringsform for vanskelig oppløselig staurosporin-derivater, spesielt N-benzoyl-staurosporin, er beskrevet. Administreringsformen er i form av en nanoemulsjon som er intravenøs appliserbar og som inneholder en kombinasjon av fosfolipider, triglycerider og partial fettsyreestere av polyoksyetylen sorbitaner som solubilisatorer.
NO954485A 1994-11-09 1995-11-08 Intravenös opplösning for et staurosporinderivat NO954485L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH337594 1994-11-09
CH59595 1995-03-02

Publications (2)

Publication Number Publication Date
NO954485D0 NO954485D0 (no) 1995-11-08
NO954485L true NO954485L (no) 1996-05-10

Family

ID=25685065

Family Applications (2)

Application Number Title Priority Date Filing Date
NO954485A NO954485L (no) 1994-11-09 1995-11-08 Intravenös opplösning for et staurosporinderivat
NO954486A NO954486L (no) 1994-11-09 1995-11-08 Farmasöytiske formuleringsgrunnlag

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO954486A NO954486L (no) 1994-11-09 1995-11-08 Farmasöytiske formuleringsgrunnlag

Country Status (11)

Country Link
US (1) US5658898A (no)
EP (2) EP0711557A1 (no)
JP (2) JPH08208486A (no)
KR (2) KR960016890A (no)
AU (2) AU3661695A (no)
CA (2) CA2162342A1 (no)
FI (2) FI955311A (no)
HU (2) HUT74423A (no)
IL (2) IL115913A0 (no)
NO (2) NO954485L (no)
NZ (2) NZ280420A (no)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996037192A1 (en) * 1995-05-26 1996-11-28 Vesifact Ag Pharmaceutical and cosmetic compositions containing sphingo- and glycolipids
WO1997021428A1 (de) * 1995-12-12 1997-06-19 Vesifact Ag Cortisolspray zur topischen verabreichung
DE19622224A1 (de) 1996-02-16 1997-08-21 Max Planck Gesellschaft Phosphatidyloligoglycerine
AU718856B2 (en) * 1996-06-18 2000-04-20 Kyowa Hakko Kogyo Co. Ltd. Liposome preparations of indolocarbazole derivatives
WO1998037869A1 (fr) * 1997-02-27 1998-09-03 Nippon Shinyaku Co., Ltd. Emulsion grasse s'administrant par voie orale
IL135989A0 (en) 1997-11-14 2001-05-20 Skyepharma Inc Processes for the production of multivesicular liposomes
US7381423B2 (en) 1998-05-11 2008-06-03 Ciba Specialty Chemicals Corp. Use of nanodispersions in cosmetic end formulations
TWI241915B (en) * 1998-05-11 2005-10-21 Ciba Sc Holding Ag A method of preparing a pharmaceutical end formulation using a nanodispersion
TW592713B (en) * 1998-05-11 2004-06-21 Ciba Sc Holding Ag Use of nanodispersions in cosmetic end formulations
US7795246B2 (en) * 1998-08-06 2010-09-14 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
US6200968B1 (en) * 1998-08-06 2001-03-13 Cephalon, Inc. Particle-forming compositions containing fused pyrrolocarbazoles
EP0988857B8 (en) * 1998-08-31 2006-05-03 Nipro Corporation Nutrient infusion preparation
GB9903547D0 (en) * 1999-02-16 1999-04-07 Novartis Ag Organic compounds
GB9924962D0 (en) * 1999-10-21 1999-12-22 Mrc Collaborative Centre Allosteric sites on muscarinic receptors
KR20090087139A (ko) 2001-10-30 2009-08-14 노파르티스 아게 Flt3 수용체 티로신 키나아제 활성의 억제제로서의 스타우로스포린 유도체
KR100422763B1 (ko) * 2002-01-17 2004-03-12 주식회사 태평양 경피흡수 촉진 능력이 우수한 식물성 나노입자의 제조 및이를 함유하는 화장료 및 의약용 외용제 조성물
KR100490365B1 (ko) * 2002-04-25 2005-05-17 한불화장품주식회사 화장료용 나노 베지클을 함유하는 화장료 조성물
CA2492989C (en) * 2002-07-23 2012-11-20 Novartis Ag Ophthalmic ointment composition comprising a drug, an ointment base and a solubilizing/dispersing agent
EP1613766A1 (de) * 2003-03-03 2006-01-11 Florian Physiologisches Institut I Lang Sgk1 als diagnostisches und therapeutisches target
GB0305941D0 (en) * 2003-03-14 2003-04-23 Camurus Ab Composition
JP2007501774A (ja) 2003-08-08 2007-02-01 ノバルティス アクチエンゲゼルシャフト スタウロスポリンを含む組み合わせ
MX2007001155A (es) * 2004-07-29 2007-08-14 Creabilis Therapeutics Spa Uso de inhibidores de k-252a y de quinasa para la prevencion o el tratamiento de patologias asociadas con hmgb1.
JP5135852B2 (ja) * 2007-03-30 2013-02-06 日油株式会社 可溶化用組成物
KR100849537B1 (ko) * 2007-07-04 2008-07-31 유효경 코엔자임 큐텐의 나노에멀젼 조성물
US20090155352A1 (en) * 2007-11-20 2009-06-18 Cephalon, Inc. Microemulsion containing indolocarbazole compound and dosage forms containing the same
JP2012051823A (ja) * 2010-08-31 2012-03-15 Fujifilm Corp 難容性薬物含有水中油型乳化組成物及びその製造方法
KR101494594B1 (ko) 2011-08-30 2015-02-23 주식회사 종근당 약리학적 활성물질의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물
WO2013086526A1 (en) * 2011-12-09 2013-06-13 The Regents Of The University Of California Liposomal drug encapsulation
KR101586791B1 (ko) 2012-12-28 2016-01-19 주식회사 종근당 GnRH 유도체의 서방성 지질 초기제제 및 이를 포함하는 약제학적 조성물
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6348214A (ja) * 1986-08-18 1988-02-29 Morishita Seiyaku Kk 1−〔2−(2,4−ジクロロフエニル)−3−メチル−1−ペンテニル〕−1h−イミダゾ−ルを含有する水中油型脂肪乳剤
US5093330A (en) * 1987-06-15 1992-03-03 Ciba-Geigy Corporation Staurosporine derivatives substituted at methylamino nitrogen
IL86632A0 (en) * 1987-06-15 1988-11-30 Ciba Geigy Ag Derivatives substituted at methyl-amino nitrogen
CH677886A5 (no) * 1989-06-26 1991-07-15 Hans Georg Prof Dr Weder
CA2130357A1 (en) * 1992-02-18 1993-08-19 Doron Friedman Dry compositions for preparing submicron emulsions
WO1995022331A1 (en) * 1994-02-18 1995-08-24 Cephalon, Inc. Aqueous indolocarbazole solutions

Also Published As

Publication number Publication date
NO954486D0 (no) 1995-11-08
IL115913A0 (en) 1996-01-31
FI955312A0 (fi) 1995-11-06
AU3661695A (en) 1996-05-23
CA2162341A1 (en) 1996-05-10
FI955311A0 (fi) 1995-11-06
AU3661795A (en) 1996-05-23
FI955312A (fi) 1996-05-10
HUT74423A (en) 1996-12-30
HUT78026A (hu) 1999-05-28
HU9503199D0 (en) 1996-01-29
NO954486L (no) 1996-05-10
IL115912A0 (en) 1996-01-31
HU9503198D0 (en) 1996-01-29
NO954485D0 (no) 1995-11-08
CA2162342A1 (en) 1996-05-10
FI955311A (fi) 1996-05-10
EP0711556A1 (de) 1996-05-15
NZ280419A (en) 1997-04-24
JPH08208522A (ja) 1996-08-13
KR960016908A (ko) 1996-06-17
EP0711557A1 (de) 1996-05-15
KR960016890A (ko) 1996-06-17
JPH08208486A (ja) 1996-08-13
NZ280420A (en) 1997-03-24
US5658898A (en) 1997-08-19

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