NO943894D0 - Galantaminderivater, en fremgangsmåte for fremstilling samt deres anvendelse som medikamenter - Google Patents

Galantaminderivater, en fremgangsmåte for fremstilling samt deres anvendelse som medikamenter

Info

Publication number
NO943894D0
NO943894D0 NO943894A NO943894A NO943894D0 NO 943894 D0 NO943894 D0 NO 943894D0 NO 943894 A NO943894 A NO 943894A NO 943894 A NO943894 A NO 943894A NO 943894 D0 NO943894 D0 NO 943894D0
Authority
NO
Norway
Prior art keywords
medicaments
preparation
alkylaminocarbonyloxy
galantamine derivatives
alkylaminocarbonyl
Prior art date
Application number
NO943894A
Other languages
English (en)
Other versions
NO943894L (no
NO307463B1 (no
Inventor
Raymond W Kosley Jr
Larry Davis
Veronica Taberna
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of NO943894D0 publication Critical patent/NO943894D0/no
Publication of NO943894L publication Critical patent/NO943894L/no
Publication of NO307463B1 publication Critical patent/NO307463B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO943894A 1993-10-15 1994-10-14 Galantaminderivater, en fremgangsmõte for fremstilling samt deres anvendelse som medikamenter NO307463B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/137,443 US6323196B1 (en) 1993-10-15 1993-10-15 Galanthamine derivatives as acetylcholinesterase inhibitors

Publications (3)

Publication Number Publication Date
NO943894D0 true NO943894D0 (no) 1994-10-14
NO943894L NO943894L (no) 1995-04-18
NO307463B1 NO307463B1 (no) 2000-04-10

Family

ID=22477457

Family Applications (1)

Application Number Title Priority Date Filing Date
NO943894A NO307463B1 (no) 1993-10-15 1994-10-14 Galantaminderivater, en fremgangsmõte for fremstilling samt deres anvendelse som medikamenter

Country Status (24)

Country Link
US (1) US6323196B1 (no)
EP (2) EP0648771B1 (no)
JP (1) JP2718637B2 (no)
KR (1) KR100189043B1 (no)
CN (1) CN1039011C (no)
AT (1) ATE201687T1 (no)
AU (1) AU679560B2 (no)
CA (1) CA2118171C (no)
CZ (1) CZ283561B6 (no)
DE (1) DE69427332T2 (no)
DK (1) DK0648771T3 (no)
EG (1) EG20747A (no)
ES (1) ES2158876T3 (no)
FI (1) FI108724B (no)
GR (1) GR3036068T3 (no)
IL (1) IL111273A (no)
NO (1) NO307463B1 (no)
NZ (1) NZ264681A (no)
PL (1) PL177754B1 (no)
PT (1) PT648771E (no)
RO (1) RO114132B1 (no)
RU (1) RU2113438C1 (no)
TW (1) TW375615B (no)
ZA (1) ZA948060B (no)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT403803B (de) 1996-04-19 1998-05-25 Sanochemia Ltd Neue benzazepinderivate, diese enthaltende arzneimittel und verwendung derselben zum herstellen von arzneimitteln
WO2000030446A1 (en) * 1998-11-23 2000-06-02 Bonnie Davis Dosage formulations for acetylcholinesterase inhibitors
HUP0104778A3 (en) 1998-12-24 2004-05-28 Janssen Pharmaceutica Nv Controlled release galantamine composition
JP2003516947A (ja) * 1999-12-10 2003-05-20 デイビス、ボニー ニコチン様物質受容体のモジュレーターとしてのガランタミンおよびリコラミンの類似物
DE50101827D1 (de) 2000-03-31 2004-05-06 Sanochemia Pharmazeutika Ag Wi Neue derivate und analoga von galanthamin
US20030162770A1 (en) * 2002-02-22 2003-08-28 Davis Bonnie M. Use of modulators of nicotinic receptors for treatment of cognitive dysfunction
WO2004041281A1 (en) * 2002-11-01 2004-05-21 Oregon Health And Science University Treatment of hyperkinetic movement disorder with donepezil
US20050048543A1 (en) * 2003-07-11 2005-03-03 Jeroen Aerssens CHRNA2 genetic markers associated with galantamine response
US20050260613A1 (en) * 2003-10-28 2005-11-24 Genaissance Pharmaceuticals LRPAP1 genetic markers associated with galantamine
US20050143350A1 (en) * 2003-11-19 2005-06-30 Seed John C. Combination drug therapy to treat obesity
US7250258B2 (en) * 2003-12-15 2007-07-31 Pgxhealth Llc CDK5 genetic markers associated with galantamine response
CA2551946A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Immediate, controlled and sustained release formulations of galantamine
CA2552114A1 (en) * 2003-12-31 2005-07-21 Actavis Group Hf Solid dosage formulations of galantamine
EP1779867A4 (en) * 2004-07-01 2009-12-02 Eisai R&D Man Co Ltd MEANS FOR PROMOTING NERVE REVENERATION
US8632800B2 (en) * 2005-05-13 2014-01-21 Alza Corporation Multilayer drug delivery system with barrier against reservoir material flow
US20080188510A1 (en) * 2005-05-23 2008-08-07 Eisai R & D Management Co., Ltd. Novel methods using zonisamide
US20090253654A1 (en) 2005-09-22 2009-10-08 Galantos Pharma Gmbh Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
EP1777222A1 (en) * 2005-09-22 2007-04-25 Galantos Pharma GmbH Cholinergic enhancers with improved blood-brain barrier permeability for the treatment of diseases accompanied by cognitive impairment
WO2007035941A2 (en) * 2005-09-23 2007-03-29 Alza Corporation Transdermal galantamine delivery system
KR100786371B1 (ko) * 2006-12-07 2007-12-17 한국화학연구원 갈란타민의 제조방법
CA2721007C (en) 2008-04-14 2014-04-29 Galantos Pharma Gmbh Derivatives of galantamine as pro-drugs for the treatment of human brain diseases
JP2013500268A (ja) * 2009-07-23 2013-01-07 シャイア エルエルシー ガランタミンアミノ酸およびペプチドプロドラッグならびにその使用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL122665B1 (en) 1978-11-21 1982-08-31 Edinen Zentar Chim Process for preparing novel dienones of narvedine type and their derivatives
US4663318A (en) 1986-01-15 1987-05-05 Bonnie Davis Method of treating Alzheimer's disease
WO1988008708A1 (en) * 1987-05-04 1988-11-17 Bonnie Davis Compounds for the treatment of alzheimer's disease
US6150354A (en) * 1987-01-15 2000-11-21 Bonnie Davis Compounds for the treatment of Alzheimer's disease
NL8800350A (nl) 1988-02-12 1989-09-01 Stichting Biomedical Research Synthetische galanthamine-derivaten, werkwijze voor het bereiden daarvan, en farmaceutische samenstellingen.
EP0515301A3 (en) 1991-05-14 1993-06-16 Ernir Snorrason Improvements in benzodiazepine treatment by cholinesterterase inhibitors
US5336675A (en) * 1991-05-14 1994-08-09 Ernir Snorrason Method of treating mania in humans
US5153193A (en) 1991-10-01 1992-10-06 Hoechst-Roussel Pharmaceuticals Incorporated Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs
US5231093A (en) * 1991-10-01 1993-07-27 Hoechst-Roussel Pharmaceuticals Incorporated Carbamate derivatives of 4-amino-3-isoxazolidinones, 3-amino-1-hydroxypyrrolidin-2-ones and 1-amino-1-cyclopropanecarboxylic acid analogs

Also Published As

Publication number Publication date
RO114132B1 (ro) 1999-01-29
PT648771E (pt) 2001-09-28
EP1020469A3 (en) 2000-07-26
NZ264681A (en) 1997-12-19
JP2718637B2 (ja) 1998-02-25
DE69427332T2 (de) 2001-10-11
EP0648771B1 (en) 2001-05-30
EP1020469A2 (en) 2000-07-19
CZ283561B6 (cs) 1998-05-13
ATE201687T1 (de) 2001-06-15
CN1039011C (zh) 1998-07-08
IL111273A0 (en) 1994-12-29
FI944822A0 (fi) 1994-10-13
CN1108658A (zh) 1995-09-20
RU94036761A (ru) 1996-09-10
CA2118171A1 (en) 1995-04-16
RU2113438C1 (ru) 1998-06-20
NO943894L (no) 1995-04-18
PL305455A1 (en) 1995-04-18
FI944822A (fi) 1995-04-16
IL111273A (en) 1998-04-05
GR3036068T3 (en) 2001-09-28
DK0648771T3 (da) 2001-08-27
ES2158876T3 (es) 2001-09-16
JPH07188238A (ja) 1995-07-25
AU679560B2 (en) 1997-07-03
EP0648771A1 (en) 1995-04-19
CZ254794A3 (en) 1995-05-17
DE69427332D1 (de) 2001-07-05
US6323196B1 (en) 2001-11-27
PL177754B1 (pl) 2000-01-31
TW375615B (en) 1999-12-01
KR100189043B1 (ko) 1999-06-01
AU7581294A (en) 1995-05-04
ZA948060B (en) 1995-06-09
CA2118171C (en) 1999-12-28
EG20747A (en) 2000-01-31
NO307463B1 (no) 2000-04-10
KR950011444A (ko) 1995-05-15
FI108724B (fi) 2002-03-15

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Legal Events

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