NO942532D0 - Fremgangsmåte og anvendelser for 4,5-diydrogeldanamycin og dets hydrokinon - Google Patents

Fremgangsmåte og anvendelser for 4,5-diydrogeldanamycin og dets hydrokinon

Info

Publication number
NO942532D0
NO942532D0 NO942532A NO942532A NO942532D0 NO 942532 D0 NO942532 D0 NO 942532D0 NO 942532 A NO942532 A NO 942532A NO 942532 A NO942532 A NO 942532A NO 942532 D0 NO942532 D0 NO 942532D0
Authority
NO
Norway
Prior art keywords
diydrogeldanamycin
hydroquinone
Prior art date
Application number
NO942532A
Other languages
English (en)
Other versions
NO942532L (no
Inventor
Walter P Cullen
Mark T Jefferson
Mikel P Moyer
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO942532D0 publication Critical patent/NO942532D0/no
Publication of NO942532L publication Critical patent/NO942532L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10Nitrogen as only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D225/00Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D225/06Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with one six-membered ring

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Saccharide Compounds (AREA)
NO942532A 1992-01-06 1994-07-05 Fremgangsmåte og anvendelser for 4,5-diydrogeldanamycin og dets hydrokinon NO942532L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81723592A 1992-01-06 1992-01-06
PCT/US1992/010189 WO1993014215A1 (en) 1992-01-06 1992-12-03 Process and uses for 4,5-dihydrogeldanamycin and its hydroquinone

Publications (2)

Publication Number Publication Date
NO942532D0 true NO942532D0 (no) 1994-07-05
NO942532L NO942532L (no) 1994-07-05

Family

ID=25222638

Family Applications (1)

Application Number Title Priority Date Filing Date
NO942532A NO942532L (no) 1992-01-06 1994-07-05 Fremgangsmåte og anvendelser for 4,5-diydrogeldanamycin og dets hydrokinon

Country Status (15)

Country Link
JP (1) JPH06510913A (no)
KR (1) KR940703923A (no)
CN (1) CN1074937A (no)
AU (1) AU3225693A (no)
BR (1) BR9207024A (no)
CA (1) CA2127457A1 (no)
CZ (1) CZ390592A3 (no)
FI (1) FI943207A0 (no)
HU (1) HU9401936D0 (no)
IL (1) IL104289A0 (no)
MX (1) MX9300011A (no)
NO (1) NO942532L (no)
PT (1) PT101169A (no)
WO (1) WO1993014215A1 (no)
ZA (1) ZA9333B (no)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0706516A1 (en) * 1993-06-29 1996-04-17 Pfizer Inc. Ansamycin derivatives as antioncogene and anticancer agents
US5932566A (en) * 1994-06-16 1999-08-03 Pfizer Inc. Ansamycin derivatives as antioncogene and anticancer agents
US6852496B1 (en) 1997-08-12 2005-02-08 Oregon Health And Science University Methods of screening for agents that promote nerve cell growth
US6872715B2 (en) 2001-08-06 2005-03-29 Kosan Biosciences, Inc. Benzoquinone ansamycins
EP1923061A1 (en) 2001-09-24 2008-05-21 Conforma Therapeutic Corporation Process for preparing 17-Allyl amino geldanamycin (17-AAG) and other ansamycins
ATE387198T1 (de) 2001-09-24 2008-03-15 Conforma Therapeutic Corp Verfahren zur herstellung von 17-allyl-amino- geldanamycin (17-aag) und anderer ansamycine
ATE433961T1 (de) 2002-02-08 2009-07-15 Conforma Therapeutics Corp Ansamycine mit verbesserten pharmakologischen und biologischen eigenschaften
TW200303363A (en) * 2002-02-25 2003-09-01 Upjohn Co Process to prepare and isolate geldanamycin
WO2005009345A2 (en) 2003-06-13 2005-02-03 Kosan Biosciences, Inc. 2-desmethyl ansamycin compounds
US6855705B1 (en) 2003-11-12 2005-02-15 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
WO2005056531A1 (en) 2003-11-12 2005-06-23 Kosan Biosciences, Inc. 11-o-methylgeldanamycin compounds
US6887993B1 (en) 2003-11-12 2005-05-03 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
US6875863B1 (en) 2003-11-12 2005-04-05 Kosan Biosciences, Inc. 11-O-methylgeldanamycin compounds
US20050148496A1 (en) * 2003-11-26 2005-07-07 Entelos, Inc. Treatment of rheumatoid arthritis with hypoxia inducible factor-1alpha antagonists
ZA200604863B (en) * 2003-12-23 2007-12-27 Infinity Pharmaceuticals Inc Analogs of benzoquinone-containing ansamycins for the treatment of cancer
KR101154351B1 (ko) 2003-12-23 2012-06-15 인피니티 디스커버리, 인코포레이티드 암 치료를 위한 벤조퀴논-함유 안사마이신의 유사체
US20060019941A1 (en) * 2003-12-23 2006-01-26 Infinity Pharmaceuticals, Inc. Analogs of benzoquinone-containing ansamycins and methods of use thereof
BRPI0609509A2 (pt) 2005-03-30 2010-04-13 Conforma Therapeutics Corp composto ou um polimorfo, solvato, tautÈmero, enanciÈmero, pró-droga ou sal farmaceuticamente aceitável do mesmo, composição farmacêutica, e, uso do composto, polimorfo, solvato, tautÈmero, enanciÈmero, pró-droga ou sal farmaceuticamente aceitável
KR20090075856A (ko) * 2006-11-09 2009-07-09 바이오티카 테크놀로지 리미티드 신규한 화합물 및 이의 제조방법
PE20081506A1 (es) 2006-12-12 2008-12-09 Infinity Discovery Inc Formulaciones de ansamicina
CN100500668C (zh) * 2006-12-19 2009-06-17 中国人民解放军军事医学科学院毒物药物研究所 格尔德霉素衍生物及其制备方法和制备药物的用途
US7855192B2 (en) 2007-01-26 2010-12-21 Kosan Biosciences, Inc. Macrolactams by engineered biosynthesis
EP2297109A4 (en) * 2008-04-21 2011-06-22 Biocon Ltd METHOD FOR ISOLATING AND PURIFYING GELDANAMYCIN
US8778921B2 (en) 2008-10-15 2014-07-15 Infinity Pharmaceuticals, Inc. Ansamycin hydroquinone compositions
CN102030764B (zh) * 2010-11-12 2012-07-04 中国医学科学院医药生物技术研究所 4,5双氢噻嗪酮格尔德霉素及其制备方法
CN103305563B (zh) * 2013-06-14 2014-12-03 湖南农业大学 一种以链霉菌提制阿里沙霉素的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3595955A (en) * 1969-03-26 1971-07-27 Upjohn Co Geldanamycin and process for producing same

Also Published As

Publication number Publication date
JPH06510913A (ja) 1994-12-08
AU3225693A (en) 1993-08-03
ZA9333B (en) 1994-07-05
KR940703923A (ko) 1994-12-12
FI943207A (fi) 1994-07-05
MX9300011A (es) 1993-12-01
FI943207A0 (fi) 1994-07-05
HU9401936D0 (en) 1994-09-28
CA2127457A1 (en) 1993-07-22
WO1993014215A1 (en) 1993-07-22
IL104289A0 (en) 1993-05-13
BR9207024A (pt) 1995-12-05
PT101169A (pt) 1994-03-31
CZ390592A3 (en) 1993-08-11
NO942532L (no) 1994-07-05
CN1074937A (zh) 1993-08-04

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