NO941084L - Neuroleptiske 2-substituerte perhydro-1-H-pyrido[1,2-aÅpyraziner - Google Patents

Neuroleptiske 2-substituerte perhydro-1-H-pyrido[1,2-aÅpyraziner

Info

Publication number
NO941084L
NO941084L NO941084A NO941084A NO941084L NO 941084 L NO941084 L NO 941084L NO 941084 A NO941084 A NO 941084A NO 941084 A NO941084 A NO 941084A NO 941084 L NO941084 L NO 941084L
Authority
NO
Norway
Prior art keywords
pct
pyrazines
neuroleptic
pyrido
alpha
Prior art date
Application number
NO941084A
Other languages
English (en)
Norwegian (no)
Other versions
NO941084D0 (no
Inventor
Gene Michael Bright
Kishor Amratlal Desai
Thomas Francis Seeger
Teresa Annette Smolarek
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO941084D0 publication Critical patent/NO941084D0/no
Publication of NO941084L publication Critical patent/NO941084L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/582Recycling of unreacted starting or intermediate materials

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
NO941084A 1991-09-25 1994-03-24 Neuroleptiske 2-substituerte perhydro-1-H-pyrido[1,2-aÅpyraziner NO941084L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76533291A 1991-09-25 1991-09-25
PCT/US1992/006625 WO1993006101A1 (en) 1991-09-25 1992-08-14 NEUROLEPTIC 2-SUBSTITUTED PERHYDRO-1-H-PYRIDO[1,2a]PYRAZINES

Publications (2)

Publication Number Publication Date
NO941084D0 NO941084D0 (no) 1994-03-24
NO941084L true NO941084L (no) 1994-03-24

Family

ID=25073279

Family Applications (1)

Application Number Title Priority Date Filing Date
NO941084A NO941084L (no) 1991-09-25 1994-03-24 Neuroleptiske 2-substituerte perhydro-1-H-pyrido[1,2-aÅpyraziner

Country Status (25)

Country Link
US (1) US5565453A (sk)
EP (1) EP0607163B1 (sk)
JP (1) JPH08827B2 (sk)
CN (1) CN1071167A (sk)
AT (1) ATE146178T1 (sk)
AU (1) AU655071B2 (sk)
BR (1) BR9206541A (sk)
CA (1) CA2118936A1 (sk)
CZ (1) CZ281775B6 (sk)
DE (1) DE69215886T2 (sk)
DK (1) DK0607163T3 (sk)
ES (1) ES2096099T3 (sk)
FI (1) FI941377A (sk)
GR (1) GR3022483T3 (sk)
HU (1) HUT71488A (sk)
IL (1) IL103204A (sk)
MX (1) MX9205385A (sk)
MY (1) MY108303A (sk)
NO (1) NO941084L (sk)
NZ (1) NZ244473A (sk)
PL (1) PL170889B1 (sk)
PT (1) PT100891A (sk)
TW (1) TW215090B (sk)
WO (1) WO1993006101A1 (sk)
ZA (1) ZA927306B (sk)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT783503E (pt) * 1994-09-30 2002-03-28 Pfizer Derivados de octa-hidro-1h-pirido¬1,2-a|pirazina 2,7-substituida
US5731307A (en) * 1994-09-30 1998-03-24 Pfizer, Inc. Neuroleptic 2,7-disubtituted perhydro-1h-pyrido 1, 2-A!pyrazines
PA8469101A1 (es) * 1998-04-09 2000-09-29 Pfizer Prod Inc Ligandos azabiciclicos de receptores 5ht1
RS20050692A (en) * 2003-03-12 2007-11-15 Pfizer Production Inc., Pyridyloxymethyl and benzisoxazole azabicyclic derivatives
CA2891122C (en) 2012-11-14 2021-07-20 The Johns Hopkins University Methods and compositions for treating schizophrenia
CN104918938B (zh) * 2012-12-20 2017-08-15 詹森药业有限公司 新颖的作为γ分泌酶调节剂的三环3,4‑二氢‑2H‑吡啶并[1,2‑a]吡嗪‑1,6‑二酮衍生物
CN104936958B (zh) 2013-01-17 2019-07-26 詹森药业有限公司 作为γ分泌酶调节剂的新颖的经取代的吡啶并-哌嗪酮衍生物
US10562897B2 (en) 2014-01-16 2020-02-18 Janssen Pharmaceutica Nv Substituted 3,4-dihydro-2H-pyrido[1,2-a]pyrazine-1,6-diones as gamma secretase modulators

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804663A (en) * 1985-03-27 1989-02-14 Janssen Pharmaceutica N.V. 3-piperidinyl-substituted 1,2-benzisoxazoles and 1,2-benzisothiazoles
US4831031A (en) * 1988-01-22 1989-05-16 Pfizer Inc. Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity
NZ230045A (en) * 1988-08-05 1990-11-27 Janssen Pharmaceutica Nv 3-piperazinylbenzazole derivatives and pharmaceutical compositions
US4957916A (en) * 1988-08-05 1990-09-18 Janssen Pharmaceutica N.V. Antipsychotic 3-piperazinylbenzazole derivatives
MX19222A (es) * 1989-01-23 1993-12-01 Pfizer Agentes ansioliticos bis-aza-biciclicos
US4956368A (en) * 1989-07-24 1990-09-11 Bristol-Myers Company Metabolites and prodrug formulations of 8-[4-[4-(1,2-benzisothiazol-3-yl)-1-piperazinyl]butyl]-8-azaspiro[4.5]decane-7,9-dione

Also Published As

Publication number Publication date
CZ395792A3 (en) 1994-05-18
CA2118936A1 (en) 1993-04-01
HU9400851D0 (en) 1994-06-28
IL103204A (en) 1996-05-14
DE69215886D1 (de) 1997-01-23
WO1993006101A1 (en) 1993-04-01
EP0607163A1 (en) 1994-07-27
CZ281775B6 (cs) 1997-01-15
GR3022483T3 (en) 1997-05-31
JPH08827B2 (ja) 1996-01-10
BR9206541A (pt) 1995-04-25
PT100891A (pt) 1993-10-29
AU2460992A (en) 1993-04-27
HUT71488A (en) 1995-11-28
ZA927306B (en) 1994-03-24
EP0607163B1 (en) 1996-12-11
PL170889B1 (pl) 1997-02-28
IL103204A0 (en) 1993-02-21
FI941377A0 (fi) 1994-03-24
ES2096099T3 (es) 1997-03-01
NO941084D0 (no) 1994-03-24
CN1071167A (zh) 1993-04-21
US5565453A (en) 1996-10-15
ATE146178T1 (de) 1996-12-15
JPH06506701A (ja) 1994-07-28
DE69215886T2 (de) 1997-04-03
AU655071B2 (en) 1994-12-01
MX9205385A (es) 1993-03-01
MY108303A (en) 1996-09-30
DK0607163T3 (da) 1997-03-17
FI941377A (fi) 1994-03-24
TW215090B (sk) 1993-10-21
NZ244473A (en) 1995-04-27

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