NO924899D0 - Fremgangsmaate for fremstilling av insulinholdige opploesninger - Google Patents

Fremgangsmaate for fremstilling av insulinholdige opploesninger

Info

Publication number
NO924899D0
NO924899D0 NO924899A NO924899A NO924899D0 NO 924899 D0 NO924899 D0 NO 924899D0 NO 924899 A NO924899 A NO 924899A NO 924899 A NO924899 A NO 924899A NO 924899 D0 NO924899 D0 NO 924899D0
Authority
NO
Norway
Prior art keywords
insulinal
procedure
solutions
preparation
insulin
Prior art date
Application number
NO924899A
Other languages
English (en)
Other versions
NO924899L (no
NO304743B1 (no
Inventor
Rainer Dickhardt
Bernhard Unger
Claudia Graefe
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19914141794 external-priority patent/DE4141794C2/de
Priority claimed from DE19924220293 external-priority patent/DE4220293C2/de
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO924899D0 publication Critical patent/NO924899D0/no
Publication of NO924899L publication Critical patent/NO924899L/no
Publication of NO304743B1 publication Critical patent/NO304743B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Inorganic Insulating Materials (AREA)
  • Soil Working Implements (AREA)
NO924899A 1991-12-18 1992-12-17 FremgangsmÕte for fremstilling av insulinholdige oppl÷sninger NO304743B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19914141794 DE4141794C2 (de) 1991-12-18 1991-12-18 Verfahren zur Reinigung von Insulin und/oder Insulinderivaten
DE19924220293 DE4220293C2 (de) 1992-06-20 1992-06-20 Verfahren zur Reinigung von Insulin und/oder Insulinderivaten

Publications (3)

Publication Number Publication Date
NO924899D0 true NO924899D0 (no) 1992-12-17
NO924899L NO924899L (no) 1993-06-21
NO304743B1 NO304743B1 (no) 1999-02-08

Family

ID=25910232

Family Applications (1)

Application Number Title Priority Date Filing Date
NO924899A NO304743B1 (no) 1991-12-18 1992-12-17 FremgangsmÕte for fremstilling av insulinholdige oppl÷sninger

Country Status (12)

Country Link
US (1) US5621073A (no)
EP (1) EP0547544B1 (no)
JP (1) JP2736214B2 (no)
AT (1) ATE150032T1 (no)
CA (1) CA2085719C (no)
DE (1) DE59208181D1 (no)
DK (1) DK0547544T3 (no)
ES (1) ES2099193T3 (no)
FI (1) FI108644B (no)
GR (1) GR3023431T3 (no)
NO (1) NO304743B1 (no)
SG (1) SG44748A1 (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19652713C2 (de) * 1996-12-18 2001-11-22 Aventis Pharma Gmbh Verfahren zur Reinigung von Insulin und Insulinderivaten durch Chromatographie an stark saurem Kationenaustauscher
DE19838097A1 (de) 1998-08-24 2000-03-02 Hoechst Marion Roussel De Gmbh Verfahren zur chromatographischen Reinigung von Insulinen
US6746853B1 (en) 1999-05-19 2004-06-08 Xencor, Inc. Proteins with insulin-like activity useful in the treatment of diabetes
WO2008031020A2 (en) * 2006-09-08 2008-03-13 Wyeth Arginine wash in protein purification using affinity chromatography
US20120214199A1 (en) * 2011-02-23 2012-08-23 Elona Biotechnologies Lis-pro proinsulin compositions and methods of producing lis-pro insulin analogs therefrom
EP2910571B1 (en) 2008-03-18 2016-10-05 Novo Nordisk A/S Protease stabilized, acylated insulin analogues
PL219335B1 (pl) * 2008-07-04 2015-04-30 Inst Biotechnologii I Antybiotyków Pochodna insuliny lub jej farmaceutycznie dopuszczalna sól, jej zastosowanie oraz zawierająca ją kompozycja farmaceutyczna
CA2870313A1 (en) 2012-04-11 2013-10-17 Novo Nordisk A/S Insulin formulations
US10421795B2 (en) 2012-12-17 2019-09-24 Merck Sharp & Dohme Corp. Process for purifying insulin and analogues thereof
EP3116531B1 (en) 2014-03-14 2021-10-20 Merck Sharp & Dohme Corp. Purifying insulin using cation exchange and reverse phase chromatography in the presence of an organic modifier and elevated temperature
EP3171888B1 (en) 2014-07-21 2022-12-28 Merck Sharp & Dohme LLC Chromatography process for purification of inlsulin and insulin analogs
MX2019006463A (es) 2016-12-16 2019-08-14 Novo Nordisk As Composiciones farmaceuticas que contienen insulina.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2629568C3 (de) * 1976-07-01 1981-09-10 Hoechst Ag, 6000 Frankfurt Verfahren zur Reinigung von Insulin, seinen Analogen und Derivaten
DE3101382A1 (de) * 1981-01-17 1982-09-02 Hoechst Ag, 6000 Frankfurt "verfahren zur herstellung von humanisulin oder dessen derivaten aus schweineinsulin oder dessen derivaten"
US5008241A (en) * 1985-03-12 1991-04-16 Novo Nordisk A/S Novel insulin peptides
WO1989001485A1 (en) * 1987-08-14 1989-02-23 Gebro Broschek Kg Purification of raw peptides by preparative medium-pressure liquid chromatography
DE3837825A1 (de) * 1988-11-08 1990-05-10 Hoechst Ag Neue insulinderivate, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
DE4028120C2 (de) * 1990-09-05 1996-09-19 Hoechst Ag Verfahren zur Reinigung von Insulin und/oder Insulinderivaten

Also Published As

Publication number Publication date
JP2736214B2 (ja) 1998-04-02
EP0547544A2 (de) 1993-06-23
JPH05308989A (ja) 1993-11-22
DK0547544T3 (da) 1997-09-08
NO924899L (no) 1993-06-21
CA2085719C (en) 2005-03-01
CA2085719A1 (en) 1993-06-19
EP0547544B1 (de) 1997-03-12
ATE150032T1 (de) 1997-03-15
NO304743B1 (no) 1999-02-08
FI108644B (fi) 2002-02-28
GR3023431T3 (en) 1997-08-29
FI925719A0 (fi) 1992-12-16
US5621073A (en) 1997-04-15
DE59208181D1 (de) 1997-04-17
FI925719A (fi) 1993-06-19
EP0547544A3 (en) 1994-07-13
SG44748A1 (en) 1997-12-19
ES2099193T3 (es) 1997-05-16

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Legal Events

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MK1K Patent expired