NO923508L - Bicykliske karboksylsyrederivater - Google Patents

Bicykliske karboksylsyrederivater

Info

Publication number
NO923508L
NO923508L NO92923508A NO923508A NO923508L NO 923508 L NO923508 L NO 923508L NO 92923508 A NO92923508 A NO 92923508A NO 923508 A NO923508 A NO 923508A NO 923508 L NO923508 L NO 923508L
Authority
NO
Norway
Prior art keywords
cor2
independently
lower alkyl
group
hydroxy
Prior art date
Application number
NO92923508A
Other languages
English (en)
Norwegian (no)
Other versions
NO923508D0 (no
Inventor
Noal Cohen
Ferdinand Kwo-Chen Lee
Keith Alan Yagaloff
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NO923508D0 publication Critical patent/NO923508D0/no
Publication of NO923508L publication Critical patent/NO923508L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76—Benzo[c]pyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
NO92923508A 1991-09-10 1992-09-09 Bicykliske karboksylsyrederivater NO923508L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75710091A 1991-09-10 1991-09-10
US07/898,852 US5273999A (en) 1991-09-10 1992-06-15 Carboxylic acid leukotriene B4 antagonists

Publications (2)

Publication Number Publication Date
NO923508D0 NO923508D0 (no) 1992-09-09
NO923508L true NO923508L (no) 1993-03-11

Family

ID=27116327

Family Applications (1)

Application Number Title Priority Date Filing Date
NO92923508A NO923508L (no) 1991-09-10 1992-09-09 Bicykliske karboksylsyrederivater

Country Status (15)

Country Link
US (2) US5273999A (fr)
EP (1) EP0531823A1 (fr)
JP (1) JPH05201915A (fr)
KR (1) KR930005998A (fr)
CN (1) CN1071423A (fr)
AU (1) AU655057B2 (fr)
CA (1) CA2077213A1 (fr)
CZ (1) CZ265492A3 (fr)
FI (1) FI924048A (fr)
HU (1) HUT66238A (fr)
IL (1) IL103058A0 (fr)
NO (1) NO923508L (fr)
NZ (1) NZ244218A (fr)
RU (1) RU2067973C1 (fr)
TW (1) TW218013B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5457124A (en) * 1993-12-07 1995-10-10 Hoffmann-La Roche Inc. Carboxylic acid Leukotriene B4 antagonists
US5753702A (en) * 1996-05-22 1998-05-19 University Of Vermont Arachidonic acid metabolite, 16-hete
US6004808A (en) * 1996-06-21 1999-12-21 Aurora Biosciences Corporation Promiscuous G-protein compositions and their use
US6416733B1 (en) 1996-10-07 2002-07-09 Bristol-Myers Squibb Pharma Company Radiopharmaceuticals for imaging infection and inflammation
JP2002515480A (ja) 1998-05-15 2002-05-28 ユニバーシティ オブ バーモント １６−ヒドロキシエイコサテトラエン酸の新規アナログ
KR100702686B1 (ko) * 1998-11-05 2007-04-04 토야마 케미칼 컴퍼니 리미티드 신규화합물 및 그 의약용도
US6019992A (en) * 1998-12-04 2000-02-01 Chesebrough-Pond's Usa Co. Cosmetic skin care compositions containing 4-chromanone
FR2791344B1 (fr) * 1999-03-25 2002-02-15 Adir Nouveaux derives dimeriques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
ES2394963T3 (es) * 2001-11-16 2013-02-07 Toyama Chemical Co., Ltd. Nuevos derivados de benzofenona o sales de los mismos
DE60322075D1 (de) * 2002-07-30 2008-08-21 Merck & Co Inc Ppar alpha selektive verbindungen zur behandlung von dyslipidämie und anderen lipidstörungen
EP1539137B1 (fr) * 2002-07-30 2010-05-26 Merck Sharp & Dohme Corp. Composes ppar alpha selectifs destines au traitement de la dyslipidemie et autres troubles lipidiques
US8093253B2 (en) * 2008-03-06 2012-01-10 Hoffmann-La Roche Inc. Leukotriene B4 inhibitors
CN102741662B (zh) * 2010-01-13 2016-09-14 Qsc公司 光控电动控制设备
ES2736599T3 (es) 2013-03-14 2020-01-03 Univ Macau Nuevos compuestos naturales antineurodegenerativos aislados a partir de Alpiniae oxyphyllae fructus y síntesis total de los mismos
CN105418576B (zh) * 2015-11-16 2018-03-13 北京新沿线医药科技发展有限公司 一种伪麻黄碱类衍生物及其抗过敏应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3776944A (en) * 1971-09-16 1973-12-04 Warner Lambert Co Tetraloneoxy acetic acids and esters thereof
EP0079637B1 (fr) * 1981-11-12 1987-01-28 FISONS plc Dérivés d'acide carboxylique anti-srs-a, leurs procédés de production et formulation pharmaceutique les contenant
ZA844519B (en) * 1983-06-24 1985-02-27 Hoffmann La Roche Dihydrobenzopyran derivatives
US4801616A (en) * 1986-03-25 1989-01-31 Eli Lilly And Company Diphenylmethanone compounds and anti-inflammatory use thereof
US4992576A (en) * 1987-01-12 1991-02-12 Eli Lilly And Company Intermediates for leukotriene antagonists
FR2615515B1 (fr) * 1987-05-22 1989-06-30 Adir Nouveaux derives du spiro 4, 5 decane, leur procede de preparation et les compositions pharmaceutiques les renfermant
US4889871A (en) * 1987-05-29 1989-12-26 G. D. Searle & Co. Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives
CA2019335C (fr) * 1989-06-27 2000-08-01 Mitoshi Konno Acides phenylakan(en)oiques
US5124350A (en) * 1990-06-28 1992-06-23 G. D. Searle & Co. Leukotriene b4 antagonists

Also Published As

Publication number Publication date
EP0531823A1 (fr) 1993-03-17
FI924048A0 (fi) 1992-09-10
NO923508D0 (no) 1992-09-09
AU655057B2 (en) 1994-12-01
IL103058A0 (en) 1993-02-21
HUT66238A (en) 1994-10-28
KR930005998A (ko) 1993-04-20
FI924048A (fi) 1993-03-11
HU9202817D0 (en) 1992-11-30
AU2219192A (en) 1993-03-11
CA2077213A1 (fr) 1993-03-11
NZ244218A (en) 1995-07-26
JPH05201915A (ja) 1993-08-10
CZ265492A3 (en) 1993-03-17
CN1071423A (zh) 1993-04-28
TW218013B (fr) 1993-12-21
US5434186A (en) 1995-07-18
RU2067973C1 (ru) 1996-10-20
US5273999A (en) 1993-12-28

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