IL103058A0 - Bicyclic carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them - Google Patents

Bicyclic carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them

Info

Publication number
IL103058A0
IL103058A0 IL103058A IL10305892A IL103058A0 IL 103058 A0 IL103058 A0 IL 103058A0 IL 103058 A IL103058 A IL 103058A IL 10305892 A IL10305892 A IL 10305892A IL 103058 A0 IL103058 A0 IL 103058A0
Authority
IL
Israel
Prior art keywords
manufacture
carboxylic acid
pharmaceutical compositions
compositions containing
acid derivatives
Prior art date
Application number
IL103058A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of IL103058A0 publication Critical patent/IL103058A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C07C57/50—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid containing condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/83—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/76—Benzo[c]pyrans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
IL103058A 1991-09-10 1992-09-04 Bicyclic carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them IL103058A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75710091A 1991-09-10 1991-09-10
US07/898,852 US5273999A (en) 1991-09-10 1992-06-15 Carboxylic acid leukotriene B4 antagonists

Publications (1)

Publication Number Publication Date
IL103058A0 true IL103058A0 (en) 1993-02-21

Family

ID=27116327

Family Applications (1)

Application Number Title Priority Date Filing Date
IL103058A IL103058A0 (en) 1991-09-10 1992-09-04 Bicyclic carboxylic acid derivatives,their manufacture and pharmaceutical compositions containing them

Country Status (15)

Country Link
US (2) US5273999A (fr)
EP (1) EP0531823A1 (fr)
JP (1) JPH05201915A (fr)
KR (1) KR930005998A (fr)
CN (1) CN1071423A (fr)
AU (1) AU655057B2 (fr)
CA (1) CA2077213A1 (fr)
CZ (1) CZ265492A3 (fr)
FI (1) FI924048A (fr)
HU (1) HUT66238A (fr)
IL (1) IL103058A0 (fr)
NO (1) NO923508L (fr)
NZ (1) NZ244218A (fr)
RU (1) RU2067973C1 (fr)
TW (1) TW218013B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5457124A (en) * 1993-12-07 1995-10-10 Hoffmann-La Roche Inc. Carboxylic acid Leukotriene B4 antagonists
US5753702A (en) * 1996-05-22 1998-05-19 University Of Vermont Arachidonic acid metabolite, 16-hete
US6004808A (en) * 1996-06-21 1999-12-21 Aurora Biosciences Corporation Promiscuous G-protein compositions and their use
US6416733B1 (en) 1996-10-07 2002-07-09 Bristol-Myers Squibb Pharma Company Radiopharmaceuticals for imaging infection and inflammation
EP1077936B1 (fr) 1998-05-15 2005-10-05 University Of Vermont Nouveaux analogues d'acide 16-hydroxyeicosatetraenoique
CN101284865A (zh) * 1998-11-05 2008-10-15 富山化学工业株式会社 新型化合物及其医药用途
US6019992A (en) * 1998-12-04 2000-02-01 Chesebrough-Pond's Usa Co. Cosmetic skin care compositions containing 4-chromanone
FR2791344B1 (fr) * 1999-03-25 2002-02-15 Adir Nouveaux derives dimeriques substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
KR100947253B1 (ko) * 2001-11-16 2010-03-11 토야마 케미칼 컴퍼니 리미티드 신규의 벤조페논유도체 또는 그 염
US7524882B2 (en) * 2002-07-30 2009-04-28 Merck & Co., Inc. PPAR alpha selective compounds for the treatment of dyslipidemia and other lipid disorders
US7297715B2 (en) * 2002-07-30 2007-11-20 Merck & Co., Inc. PPAR alpha selective compounds for the treatment of dyslipidemia and other lipid disorders
US8093253B2 (en) * 2008-03-06 2012-01-10 Hoffmann-La Roche Inc. Leukotriene B4 inhibitors
WO2011087966A1 (fr) * 2010-01-13 2011-07-21 Qsc Audio Products, Llc Dispositif de commande motorisé à commande optique
CN105431405B (zh) 2013-03-14 2018-06-01 澳门大学 分离自益智仁的新抗神经变性天然化合物及其全合成
CN105418576B (zh) * 2015-11-16 2018-03-13 北京新沿线医药科技发展有限公司 一种伪麻黄碱类衍生物及其抗过敏应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3776944A (en) * 1971-09-16 1973-12-04 Warner Lambert Co Tetraloneoxy acetic acids and esters thereof
ATE25251T1 (de) * 1981-11-12 1987-02-15 Fisons Plc Anti srs-a carbonsaeure-derivate, verfahren zu deren herstellung und diese enthaltende pharmazeutische formulierungen.
ZA844519B (en) * 1983-06-24 1985-02-27 Hoffmann La Roche Dihydrobenzopyran derivatives
US4801616A (en) * 1986-03-25 1989-01-31 Eli Lilly And Company Diphenylmethanone compounds and anti-inflammatory use thereof
US4992576A (en) * 1987-01-12 1991-02-12 Eli Lilly And Company Intermediates for leukotriene antagonists
FR2615515B1 (fr) * 1987-05-22 1989-06-30 Adir Nouveaux derives du spiro 4, 5 decane, leur procede de preparation et les compositions pharmaceutiques les renfermant
US4889871A (en) * 1987-05-29 1989-12-26 G. D. Searle & Co. Alkoxy-substituted dihydrobenzopyran-2-carboxylate derivatives
CA2019335C (fr) * 1989-06-27 2000-08-01 Mitoshi Konno Acides phenylakan(en)oiques
US5124350A (en) * 1990-06-28 1992-06-23 G. D. Searle & Co. Leukotriene b4 antagonists

Also Published As

Publication number Publication date
US5273999A (en) 1993-12-28
AU655057B2 (en) 1994-12-01
JPH05201915A (ja) 1993-08-10
US5434186A (en) 1995-07-18
FI924048A0 (fi) 1992-09-10
HUT66238A (en) 1994-10-28
CN1071423A (zh) 1993-04-28
RU2067973C1 (ru) 1996-10-20
TW218013B (fr) 1993-12-21
AU2219192A (en) 1993-03-11
CZ265492A3 (en) 1993-03-17
NO923508L (no) 1993-03-11
EP0531823A1 (fr) 1993-03-17
CA2077213A1 (fr) 1993-03-11
HU9202817D0 (en) 1992-11-30
KR930005998A (ko) 1993-04-20
NO923508D0 (no) 1992-09-09
FI924048A (fi) 1993-03-11
NZ244218A (en) 1995-07-26

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