NO922833L - Chelaterende forbindelser - Google Patents
Chelaterende forbindelserInfo
- Publication number
- NO922833L NO922833L NO92922833A NO922833A NO922833L NO 922833 L NO922833 L NO 922833L NO 92922833 A NO92922833 A NO 92922833A NO 922833 A NO922833 A NO 922833A NO 922833 L NO922833 L NO 922833L
- Authority
- NO
- Norway
- Prior art keywords
- relations
- chelating
- chelating relations
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Radiology & Medical Imaging (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Detergent Compositions (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB909001246A GB9001246D0 (en) | 1990-01-19 | 1990-01-19 | Compounds |
GB909007984A GB9007984D0 (en) | 1990-01-19 | 1990-04-09 | Compounds |
PCT/EP1991/000125 WO1991010669A1 (en) | 1990-01-19 | 1991-01-18 | Chelating compounds |
Publications (3)
Publication Number | Publication Date |
---|---|
NO922833D0 NO922833D0 (no) | 1992-07-17 |
NO922833L true NO922833L (no) | 1992-07-28 |
NO305032B1 NO305032B1 (no) | 1999-03-22 |
Family
ID=26296526
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO922833A NO305032B1 (no) | 1990-01-19 | 1992-07-17 | Chelaterende forbindelser |
Country Status (6)
Country | Link |
---|---|
US (1) | US5322681A (no) |
EP (1) | EP0511275A1 (no) |
JP (1) | JP3131219B2 (no) |
CA (1) | CA2072080A1 (no) |
NO (1) | NO305032B1 (no) |
WO (1) | WO1991010669A1 (no) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5334371A (en) * | 1988-07-20 | 1994-08-02 | Schering Aktiengesellschaft | Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI |
FR2644785B1 (fr) * | 1989-03-24 | 1991-07-05 | Guerbet Sa | Nouveaux ligands macrocycliques azotes, procede de preparation, complexes metalliques formes par ces ligands et composition de diagnostic les contenant |
GB9115375D0 (en) * | 1991-07-17 | 1991-09-04 | Salutar Inc | Compounds |
US5330737A (en) * | 1991-12-06 | 1994-07-19 | Mallinckrodt Medical, Inc. | Nitrogen-sulfur ligands as opiate receptor drug mimics |
US5428139A (en) * | 1991-12-10 | 1995-06-27 | The Dow Chemical Company | Bicyclopolyazamacrocyclophosphonic acid complexes for use as radiopharmaceuticals |
WO1994026313A1 (en) * | 1993-05-06 | 1994-11-24 | The Dow Chemical Company | Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as contrast agents |
DE69223504T2 (de) * | 1991-12-10 | 1998-04-02 | The Dow Chemical Co., Midland, Mich. | Bicycloazamakrocyclophosphon-Säure, Komplexe, Konjugate, Kontrastmittel und Herstellung |
US5739294A (en) * | 1991-12-10 | 1998-04-14 | The Dow Chemical Company | Bicyclopol yazamacrocyclophosphonic acid complexes for use as contrast agents |
US5674468A (en) * | 1992-03-06 | 1997-10-07 | Nycomed Imaging As | Contrast agents comprising gas-containing or gas-generating polymer microparticles or microballoons |
KR100306331B1 (ko) * | 1993-05-06 | 2001-12-28 | 그래햄 이. 테일러 | 비사이클로폴리아자매크로사이클로카복실산착체,그의결합체,그의제조방법및조영제로서의그의용도 |
AU4237493A (en) * | 1993-05-06 | 1994-12-12 | Dow Chemical Company, The | Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as radiopharmaceuticals |
WO1994026755A1 (en) * | 1993-05-06 | 1994-11-24 | The Dow Chemical Company | Bicyclopolyazamacrocyclophosphonic acid complexes, a process for their preparation, and their conjugates, for use as radiopharmaceuticals |
JPH08509976A (ja) * | 1993-05-06 | 1996-10-22 | ザ・ダウ・ケミカル・カンパニー | コントラスト剤として使用するためのビシクロポリアザマクロシクロホスホン酸、それらの錯体および複合体ならびにそれらの製造方法 |
DE4318369C1 (de) * | 1993-05-28 | 1995-02-09 | Schering Ag | Verwendung von makrocyclischen Metallkomplexen als Temperatursonden |
US5358704A (en) * | 1993-09-30 | 1994-10-25 | Bristol-Myers Squibb | Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents |
US5417959A (en) * | 1993-10-04 | 1995-05-23 | Mallinckrodt Medical, Inc. | Functionalized aza-crytand ligands for diagnostic imaging applications |
AU1681795A (en) * | 1994-01-14 | 1995-08-01 | Mallinckrodt Medical, Inc. | Functionalized aza-macrobicyclic ligands for imaging applications |
AU1694895A (en) * | 1994-01-28 | 1995-08-15 | Mallinckrodt Medical, Inc. | Functionalized aza-bimacrocyclic ligands for imaging applications |
US5476644A (en) * | 1994-04-13 | 1995-12-19 | Sterling Winthrop Inc. | Cyclic triamine chelating agents |
US5663161A (en) * | 1995-02-17 | 1997-09-02 | The Research Foundation Of State University Of New York | Anti-viral triaza compounds |
US6770261B2 (en) | 1995-06-02 | 2004-08-03 | Research Corporation Technologies | Magnetic resonance imaging agents for the detection of physiological agents |
US5980862A (en) * | 1995-06-02 | 1999-11-09 | Research Corporation Technologies | Magnetic resonance imaging agents for the detection of physiological agents |
US5707605A (en) * | 1995-06-02 | 1998-01-13 | Research Corporation Technologies | Magnetic resonance imaging agents for the detection of physiological agents |
US6713045B1 (en) | 1995-06-02 | 2004-03-30 | Research Corporation Technologies, Inc. | Targeted magnetic resonance imaging agents for the detection of physiological processes |
JPH11507621A (ja) * | 1995-06-07 | 1999-07-06 | モンサント カンパニー | 置換ポリアザ大環状化合物の製造法 |
JPH11511168A (ja) | 1995-08-17 | 1999-09-28 | モンサント カンパニー | 窒素含有大環状リガンドの金属錯体の生体分子結合体を使用する診断造影検査方法 |
EP0844889A1 (en) * | 1995-08-17 | 1998-06-03 | Monsanto Company | Methods of diagnostic image analysis using metal complexes of nitrogen-containing macrocyclic ligands |
US5900228A (en) | 1996-07-31 | 1999-05-04 | California Institute Of Technology | Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye |
IT1291624B1 (it) * | 1997-04-18 | 1999-01-11 | Bracco Spa | Chelati complessi di metalli paramagnetici a bassa tossicita' |
US6214817B1 (en) | 1997-06-20 | 2001-04-10 | Monsanto Company | Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity |
US6713046B1 (en) | 1997-10-27 | 2004-03-30 | Research Corporation Technologies | Magnetic resonance imaging agents for the delivery of therapeutic agents |
AU752812B2 (en) | 1997-11-17 | 2002-10-03 | Research Corporation Technologies, Inc. | Magnetic resonance imaging agents for the detection of physiological agents |
CA2334809A1 (en) * | 1998-06-05 | 1999-12-09 | Board Of Regents, The University Of Texas System | Texaphyrin conjugates and uses thereof |
US6673333B1 (en) | 2000-05-04 | 2004-01-06 | Research Corporation Technologies, Inc. | Functional MRI agents for cancer imaging |
US6656450B2 (en) | 2000-07-17 | 2003-12-02 | California Institute Of Technology, Inc. | Macrocyclic magnetic resonance imaging contrast agents |
US7029655B2 (en) | 2000-10-04 | 2006-04-18 | California Institute Of Technology | Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits |
US20020197648A1 (en) * | 2001-05-02 | 2002-12-26 | Silva Robin M. | High throughput screening methods using magnetic resonance imaging agents |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2387976A (en) * | 1943-05-01 | 1945-10-30 | Martin Dennis Company | Method of forming carboxylic substituted amines |
US2407645A (en) * | 1943-06-21 | 1946-09-17 | Martin Dennis Company | Aliphatic polycarboxylic amino acids and process of making them |
US2751390A (en) * | 1950-09-02 | 1956-06-19 | Dow Chemical Co | Di-pyridyl aliphatic alkylene polyamine poly acids |
DE3129906C3 (de) * | 1981-07-24 | 1996-12-19 | Schering Ag | Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik |
US4957939A (en) * | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
NL194579C (nl) * | 1983-01-21 | 2002-08-05 | Schering Ag | Diagnostisch middel. |
US4880008A (en) * | 1985-05-08 | 1989-11-14 | The General Hospital Corporation | Vivo enhancement of NMR relaxivity |
US4899755A (en) * | 1985-05-08 | 1990-02-13 | The General Hospital Corporation | Hepatobiliary NMR contrast agents |
US4678667A (en) * | 1985-07-02 | 1987-07-07 | 501 Regents of the University of California | Macrocyclic bifunctional chelating agents |
US4994560A (en) * | 1987-06-24 | 1991-02-19 | The Dow Chemical Company | Functionalized polyamine chelants and radioactive rhodium complexes thereof for conjugation to antibodies |
EP0299795B1 (en) * | 1987-07-16 | 1992-03-18 | Nycomed As | Aminopolycarboxylic acids and derivatives thereof |
GB8801646D0 (en) * | 1988-01-26 | 1988-02-24 | Nycomed As | Chemical compounds |
ATE107276T1 (de) * | 1988-02-03 | 1994-07-15 | Hybritech Inc | Modifizierte haptene, nützlich als bildformendes agens und als arzneimittel. |
CA1340527C (en) * | 1988-05-31 | 1999-05-04 | Lidia Vallarino | Macrocyclic complexes of yttrium, the lanthanides and the actinides having peripheral coupling functionalities |
DE3825040A1 (de) * | 1988-07-20 | 1990-01-25 | Schering Ag, 13353 Berlin | 5- oder 6-ring- enthaltende makrocyclische polyaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
FR2644785B1 (fr) * | 1989-03-24 | 1991-07-05 | Guerbet Sa | Nouveaux ligands macrocycliques azotes, procede de preparation, complexes metalliques formes par ces ligands et composition de diagnostic les contenant |
-
1991
- 1991-01-18 WO PCT/EP1991/000125 patent/WO1991010669A1/en not_active Application Discontinuation
- 1991-01-18 JP JP03503082A patent/JP3131219B2/ja not_active Expired - Fee Related
- 1991-01-18 EP EP91902985A patent/EP0511275A1/en not_active Withdrawn
- 1991-01-18 CA CA002072080A patent/CA2072080A1/en not_active Abandoned
-
1992
- 1992-07-17 NO NO922833A patent/NO305032B1/no unknown
- 1992-07-17 US US07/910,318 patent/US5322681A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
NO305032B1 (no) | 1999-03-22 |
EP0511275A1 (en) | 1992-11-04 |
US5322681A (en) | 1994-06-21 |
NO922833D0 (no) | 1992-07-17 |
JP3131219B2 (ja) | 2001-01-31 |
JPH05503519A (ja) | 1993-06-10 |
CA2072080A1 (en) | 1991-07-20 |
WO1991010669A1 (en) | 1991-07-25 |
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