NO922833D0 - Chelaterende forbindelser - Google Patents

Chelaterende forbindelser

Info

Publication number
NO922833D0
NO922833D0 NO1992922833A NO922833A NO922833D0 NO 922833 D0 NO922833 D0 NO 922833D0 NO 1992922833 A NO1992922833 A NO 1992922833A NO 922833 A NO922833 A NO 922833A NO 922833 D0 NO922833 D0 NO 922833D0
Authority
NO
Norway
Prior art keywords
relations
chelating
chelating relations
Prior art date
Application number
NO1992922833A
Other languages
English (en)
Other versions
NO922833L (no
NO305032B1 (no
Inventor
Jo Klaveness
Paal Rongved
Arne Berg
Original Assignee
Nycomed As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB909001246A external-priority patent/GB9001246D0/en
Application filed by Nycomed As filed Critical Nycomed As
Publication of NO922833D0 publication Critical patent/NO922833D0/no
Publication of NO922833L publication Critical patent/NO922833L/no
Publication of NO305032B1 publication Critical patent/NO305032B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/04—Chelating agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Detergent Compositions (AREA)
NO922833A 1990-01-19 1992-07-17 Chelaterende forbindelser NO305032B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB909001246A GB9001246D0 (en) 1990-01-19 1990-01-19 Compounds
GB909007984A GB9007984D0 (en) 1990-01-19 1990-04-09 Compounds
PCT/EP1991/000125 WO1991010669A1 (en) 1990-01-19 1991-01-18 Chelating compounds

Publications (3)

Publication Number Publication Date
NO922833D0 true NO922833D0 (no) 1992-07-17
NO922833L NO922833L (no) 1992-07-28
NO305032B1 NO305032B1 (no) 1999-03-22

Family

ID=26296526

Family Applications (1)

Application Number Title Priority Date Filing Date
NO922833A NO305032B1 (no) 1990-01-19 1992-07-17 Chelaterende forbindelser

Country Status (6)

Country Link
US (1) US5322681A (no)
EP (1) EP0511275A1 (no)
JP (1) JP3131219B2 (no)
CA (1) CA2072080A1 (no)
NO (1) NO305032B1 (no)
WO (1) WO1991010669A1 (no)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5334371A (en) * 1988-07-20 1994-08-02 Schering Aktiengesellschaft Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI
FR2644785B1 (fr) * 1989-03-24 1991-07-05 Guerbet Sa Nouveaux ligands macrocycliques azotes, procede de preparation, complexes metalliques formes par ces ligands et composition de diagnostic les contenant
GB9115375D0 (en) * 1991-07-17 1991-09-04 Salutar Inc Compounds
US5330737A (en) * 1991-12-06 1994-07-19 Mallinckrodt Medical, Inc. Nitrogen-sulfur ligands as opiate receptor drug mimics
US5428139A (en) * 1991-12-10 1995-06-27 The Dow Chemical Company Bicyclopolyazamacrocyclophosphonic acid complexes for use as radiopharmaceuticals
US5739294A (en) * 1991-12-10 1998-04-14 The Dow Chemical Company Bicyclopol yazamacrocyclophosphonic acid complexes for use as contrast agents
WO1994026313A1 (en) * 1993-05-06 1994-11-24 The Dow Chemical Company Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as contrast agents
EP0735040A3 (en) * 1991-12-10 1997-02-26 Dow Chemical Co Bicyclopolyazamacrocyclophosphonic acids, their complexes and conjugates, and their preparation
US5674468A (en) * 1992-03-06 1997-10-07 Nycomed Imaging As Contrast agents comprising gas-containing or gas-generating polymer microparticles or microballoons
KR100306331B1 (ko) * 1993-05-06 2001-12-28 그래햄 이. 테일러 비사이클로폴리아자매크로사이클로카복실산착체,그의결합체,그의제조방법및조영제로서의그의용도
WO1994026315A1 (en) * 1993-05-06 1994-11-24 The Dow Chemical Company Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as radiopharmaceuticals
EP0696290A1 (en) * 1993-05-06 1996-02-14 The Dow Chemical Company Bicyclopolyazamacrocyclophosphonic acids, their complexes and conjugates, for use as contrast agents, and processes for their preparation
WO1994026755A1 (en) * 1993-05-06 1994-11-24 The Dow Chemical Company Bicyclopolyazamacrocyclophosphonic acid complexes, a process for their preparation, and their conjugates, for use as radiopharmaceuticals
DE4318369C1 (de) * 1993-05-28 1995-02-09 Schering Ag Verwendung von makrocyclischen Metallkomplexen als Temperatursonden
US5358704A (en) * 1993-09-30 1994-10-25 Bristol-Myers Squibb Hepatobiliary tetraazamacrocyclic magnetic resonance contrast agents
US5417959A (en) * 1993-10-04 1995-05-23 Mallinckrodt Medical, Inc. Functionalized aza-crytand ligands for diagnostic imaging applications
AU1681795A (en) * 1994-01-14 1995-08-01 Mallinckrodt Medical, Inc. Functionalized aza-macrobicyclic ligands for imaging applications
AU1694895A (en) * 1994-01-28 1995-08-15 Mallinckrodt Medical, Inc. Functionalized aza-bimacrocyclic ligands for imaging applications
US5476644A (en) * 1994-04-13 1995-12-19 Sterling Winthrop Inc. Cyclic triamine chelating agents
US5663161A (en) 1995-02-17 1997-09-02 The Research Foundation Of State University Of New York Anti-viral triaza compounds
US6770261B2 (en) 1995-06-02 2004-08-03 Research Corporation Technologies Magnetic resonance imaging agents for the detection of physiological agents
US5980862A (en) * 1995-06-02 1999-11-09 Research Corporation Technologies Magnetic resonance imaging agents for the detection of physiological agents
US6713045B1 (en) 1995-06-02 2004-03-30 Research Corporation Technologies, Inc. Targeted magnetic resonance imaging agents for the detection of physiological processes
US5707605A (en) * 1995-06-02 1998-01-13 Research Corporation Technologies Magnetic resonance imaging agents for the detection of physiological agents
CA2224088A1 (en) * 1995-06-07 1996-12-19 Monsanto Company Process for preparing substituted polyazamacrocycles
EP0846003A1 (en) 1995-08-17 1998-06-10 Monsanto Company Methods of diagnostic image analysis using bioconjugates of metal complexes of nitrogen-containing macrocyclic ligands
JPH11514971A (ja) * 1995-08-17 1999-12-21 モンサント カンパニー 窒素含有大環状リガンドの金属錯体を使用する診断造影検査方法
US5900228A (en) 1996-07-31 1999-05-04 California Institute Of Technology Bifunctional detection agents having a polymer covalently linked to an MRI agent and an optical dye
IT1291624B1 (it) * 1997-04-18 1999-01-11 Bracco Spa Chelati complessi di metalli paramagnetici a bassa tossicita'
US6214817B1 (en) 1997-06-20 2001-04-10 Monsanto Company Substituted pyridino pentaazamacrocyle complexes having superoxide dismutase activity
US6713046B1 (en) 1997-10-27 2004-03-30 Research Corporation Technologies Magnetic resonance imaging agents for the delivery of therapeutic agents
CA2309749A1 (en) 1997-11-17 1999-05-27 Research Corporation Technologies, Inc. Magnetic resonance imaging agents for the detection of physiological agents
JP2002516878A (ja) * 1998-06-05 2002-06-11 ボード オブ リージェンツ， ザ ユニバーシティ オブ テキサス システム テキサフィリン結合体およびその使用
US6673333B1 (en) 2000-05-04 2004-01-06 Research Corporation Technologies, Inc. Functional MRI agents for cancer imaging
AU2001276956A1 (en) 2000-07-17 2002-01-30 California Institute Of Technology Macrocyclic mri contrast agents
US7029655B2 (en) 2000-10-04 2006-04-18 California Institute Of Technology Magnetic resonance imaging agents for in vivo labeling and detection of amyloid deposits
WO2002087632A1 (en) * 2001-05-02 2002-11-07 Metaprobe, Inc. High throughput screening methods using magnetic resonance imaging agents

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2387976A (en) * 1943-05-01 1945-10-30 Martin Dennis Company Method of forming carboxylic substituted amines
US2407645A (en) * 1943-06-21 1946-09-17 Martin Dennis Company Aliphatic polycarboxylic amino acids and process of making them
US2751390A (en) * 1950-09-02 1956-06-19 Dow Chemical Co Di-pyridyl aliphatic alkylene polyamine poly acids
US4957939A (en) * 1981-07-24 1990-09-18 Schering Aktiengesellschaft Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging
DE3129906C3 (de) * 1981-07-24 1996-12-19 Schering Ag Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik
NL194579C (nl) * 1983-01-21 2002-08-05 Schering Ag Diagnostisch middel.
US4899755A (en) * 1985-05-08 1990-02-13 The General Hospital Corporation Hepatobiliary NMR contrast agents
US4880008A (en) * 1985-05-08 1989-11-14 The General Hospital Corporation Vivo enhancement of NMR relaxivity
US4678667A (en) * 1985-07-02 1987-07-07 501 Regents of the University of California Macrocyclic bifunctional chelating agents
US4994560A (en) * 1987-06-24 1991-02-19 The Dow Chemical Company Functionalized polyamine chelants and radioactive rhodium complexes thereof for conjugation to antibodies
ES2033433T3 (es) * 1987-07-16 1993-03-16 Nycomed As Procedimiento para preparar acidos aminopolicarboxilicos y sus derivados.
GB8801646D0 (en) * 1988-01-26 1988-02-24 Nycomed As Chemical compounds
DK47389A (da) * 1988-02-03 1989-08-04 Hybritech Inc Farmakokinetisk modificerede hapten-derivater til radiomaerkning af antistoffer eller til anvendelse som radioterapeutiske midler
CA1340527C (en) * 1988-05-31 1999-05-04 Lidia Vallarino Macrocyclic complexes of yttrium, the lanthanides and the actinides having peripheral coupling functionalities
DE3825040A1 (de) * 1988-07-20 1990-01-25 Schering Ag 5- oder 6-ring- enthaltende makrocyclische polyaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
FR2644785B1 (fr) * 1989-03-24 1991-07-05 Guerbet Sa Nouveaux ligands macrocycliques azotes, procede de preparation, complexes metalliques formes par ces ligands et composition de diagnostic les contenant

Also Published As

Publication number Publication date
NO922833L (no) 1992-07-28
EP0511275A1 (en) 1992-11-04
NO305032B1 (no) 1999-03-22
CA2072080A1 (en) 1991-07-20
JPH05503519A (ja) 1993-06-10
WO1991010669A1 (en) 1991-07-25
US5322681A (en) 1994-06-21
JP3131219B2 (ja) 2001-01-31

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