NO920762L - Polypeptid med antikoagulerende aktivitet - Google Patents

Polypeptid med antikoagulerende aktivitet

Info

Publication number
NO920762L
NO920762L NO92920762A NO920762A NO920762L NO 920762 L NO920762 L NO 920762L NO 92920762 A NO92920762 A NO 92920762A NO 920762 A NO920762 A NO 920762A NO 920762 L NO920762 L NO 920762L
Authority
NO
Norway
Prior art keywords
polypeptid
anticoagulating activity
anticoagulating
activity
Prior art date
Application number
NO92920762A
Other languages
English (en)
Other versions
NO302527B1 (no
NO920762D0 (no
Inventor
Atsushi Nii
Hideaki Morishita
Akio Uemura
Ei Mochida
Original Assignee
Mochida Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharm Co Ltd filed Critical Mochida Pharm Co Ltd
Publication of NO920762D0 publication Critical patent/NO920762D0/no
Publication of NO920762L publication Critical patent/NO920762L/no
Publication of NO302527B1 publication Critical patent/NO302527B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/7455—Thrombomodulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO920762A 1990-06-27 1992-02-26 Fremgangsmåte ved fremstilling av polypeptid med antikoagulerende aktivitet NO302527B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP16876690 1990-06-27
PCT/JP1991/000873 WO1992000325A1 (en) 1990-06-27 1991-06-27 Anticoagulant polypeptides

Publications (3)

Publication Number Publication Date
NO920762D0 NO920762D0 (no) 1992-02-26
NO920762L true NO920762L (no) 1992-04-24
NO302527B1 NO302527B1 (no) 1998-03-16

Family

ID=15874056

Family Applications (1)

Application Number Title Priority Date Filing Date
NO920762A NO302527B1 (no) 1990-06-27 1992-02-26 Fremgangsmåte ved fremstilling av polypeptid med antikoagulerende aktivitet

Country Status (8)

Country Link
US (2) US5516659A (no)
EP (1) EP0489180A4 (no)
JP (1) JP3189052B2 (no)
AU (1) AU643306B2 (no)
CA (1) CA2065409C (no)
FI (1) FI106206B (no)
NO (1) NO302527B1 (no)
WO (1) WO1992000325A1 (no)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE180496T1 (de) * 1987-01-08 1999-06-15 Asahi Chemical Ind Peptid zur beschleunigung der wirkung des proteins-c mit thrombin
CA2156255C (en) * 1993-12-17 2008-02-05 Yasuyuki Kunihiro Soluble thrombomodulin-containing composition
US6465620B1 (en) * 2000-01-21 2002-10-15 Hyseq, Inc. Methods and materials relating to novel von Willebrand/Thrombospondin-like polypeptides and polynucleotides
US7691604B1 (en) 2000-05-04 2010-04-06 California Institute Of Technology MRG polypeptides and nucleic acids encoding the same
US7510845B2 (en) * 2000-05-04 2009-03-31 California Institute Of Technology Assay employing G protein-coupled receptor expressed in dorsal root ganglia
US20030092035A1 (en) * 2000-05-04 2003-05-15 Anderson David J. Pain signaling molecules
US20030152941A1 (en) * 2000-06-21 2003-08-14 Boyle Bryan J. Nucleic acids encoding novel von Willebrand/Thrombospondin factor-like polypeptides and uses of same
EP1317253A4 (en) * 2000-07-28 2006-04-26 Univ Emory BIOLOGICAL COMPONENT COMPRISING AN ARTIFICIAL MEMBRANE
CA2447629A1 (en) * 2001-05-25 2002-12-05 Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw The lectin-like domain of thrombomodulin and its therapeutic use
JP4187141B2 (ja) * 2002-04-12 2008-11-26 興和株式会社 新規なトロンボモジュリン発現促進剤
US20040121410A1 (en) * 2002-12-20 2004-06-24 Anderson David J. Pain signaling molecules
MX2009003384A (es) 2006-10-06 2009-04-08 Asahi Kasei Pharma Corp Agente terapeutico y/o de mejoramiento para la coagulacion intravascular diseminada.
NZ579873A (en) 2007-03-23 2011-11-25 Asahi Kasei Pharma Corp Method for producing soluble thrombomodulin of high purity
US20120165244A1 (en) * 2008-10-30 2012-06-28 Hua-Lin Wu Methods for binding lewis y antigen
KR20110083665A (ko) * 2008-11-12 2011-07-20 일라이 릴리 앤드 캄파니 가용성 트롬보모듈린 변이체 조성물 및 가용성 트롬보모듈린 변이체의 사용 방법
JP2011178687A (ja) * 2010-02-26 2011-09-15 Kochi Univ 造血細胞移植に伴う疼痛の予防および／または治療剤
CA2796452C (en) 2010-04-30 2017-12-05 Asahi Kasei Pharma Corporation Highly-purified soluble thrombomodulin and method for producing same
CL2011001887A1 (es) 2010-08-05 2012-02-03 Council Scient Ind Res Construcciones de proteinas quimericas que poseen propiedades anticoagulantes y tromboliticas; secuencia de acido nucleico que las codifica; vector; celula huesped; metodo de preparacion; formulacion farmaceutica que las comprende; y su uso para inhibir la trombina.
US8772239B2 (en) 2011-11-15 2014-07-08 Asahi Kasei Pharma Corporation Medicament for therapeutic treatment and/or improvement of sepsis
HUE045997T2 (hu) 2012-05-31 2020-01-28 Univ Kinki Hatóanyag rákellenes szer által okozott perifériás neuropátiás fájdalom megelõzésére és/vagy kezelésére
US11497795B2 (en) 2018-09-28 2022-11-15 Asahi Kasei Pharma Corporation Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent
CA3116686A1 (en) 2018-10-22 2020-04-30 Asahi Kasei Pharma Corporation Medicament for therapeutic treatment and/or improvement of sepsis accompanied by coagulopathy
CN114686443B (zh) * 2020-12-31 2023-11-03 广州万孚生物技术股份有限公司 杂交瘤细胞、抗血栓调节蛋白单克隆抗体及其制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60199819A (ja) * 1984-03-23 1985-10-09 Kowa Co トロンビン結合性物質およびその製法
JPH0689014B2 (ja) * 1986-01-21 1994-11-09 興和株式会社 トロンビン結合性物質およびその製法
JPS6330423A (ja) * 1986-07-22 1988-02-09 Kowa Co トロンビン結合性物質およびその製法
DE3750664T2 (de) * 1986-07-15 1995-06-22 Kowa Co Throminbindende Substanz und Verfahren zu ihrer Herstellung.
JPS63146898A (ja) * 1986-07-15 1988-06-18 Kowa Co トロンビン結合性物質およびその製法
ATE180496T1 (de) * 1987-01-08 1999-06-15 Asahi Chemical Ind Peptid zur beschleunigung der wirkung des proteins-c mit thrombin
US4912207A (en) * 1987-05-06 1990-03-27 Washington University DNA clone of human thrombomodulin and portions thereof
DK299087D0 (da) * 1987-06-12 1987-06-12 Novo Industri As Proteins and derivatives thereof
JPH0219399A (ja) * 1988-07-05 1990-01-23 Oklahoma Medical Res Found トロンビン結合ポリピペプチド
US5202421A (en) * 1988-12-27 1993-04-13 Mochida Pharmaceutical Co., Ltd. Anticoagulant substance obtained from urine and process for the preparation thereof
US5256770A (en) * 1990-04-09 1993-10-26 Schering Ag Oxidation resistant thrombomodulin analogs
US5273962A (en) * 1990-11-30 1993-12-28 Kowa Co., Ltd. Human urinary thrombomodulin with a modified glycosaminoglycan (GAG) binding site

Also Published As

Publication number Publication date
AU643306B2 (en) 1993-11-11
NO302527B1 (no) 1998-03-16
WO1992000325A1 (en) 1992-01-09
JP3189052B2 (ja) 2001-07-16
EP0489180A1 (en) 1992-06-10
NO920762D0 (no) 1992-02-26
US5695964A (en) 1997-12-09
CA2065409C (en) 2002-05-14
AU8080091A (en) 1992-01-23
FI920889A0 (fi) 1992-02-27
US5516659A (en) 1996-05-14
EP0489180A4 (en) 1993-03-31
FI106206B (fi) 2000-12-15
CA2065409A1 (en) 1991-12-28

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