FI920889A0 - Antikoagulantpolypeptider. - Google Patents

Antikoagulantpolypeptider.

Info

Publication number
FI920889A0
FI920889A0 FI920889A FI920889A FI920889A0 FI 920889 A0 FI920889 A0 FI 920889A0 FI 920889 A FI920889 A FI 920889A FI 920889 A FI920889 A FI 920889A FI 920889 A0 FI920889 A0 FI 920889A0
Authority
FI
Finland
Prior art keywords
antikoagulantpolypeptider
Prior art date
Application number
FI920889A
Other languages
English (en)
Other versions
FI106206B (fi
Inventor
Atsushi C O Mochida Pharma Nii
Hideaki C O Mochida Morishita
Akio C O Mochida Pharma Uemura
Ei C O Mochida Pharmac Mochida
Original Assignee
Mochida Pharm Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mochida Pharm Co Ltd filed Critical Mochida Pharm Co Ltd
Publication of FI920889A0 publication Critical patent/FI920889A0/fi
Application granted granted Critical
Publication of FI106206B publication Critical patent/FI106206B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/7455—Thrombomodulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI920889A 1990-06-27 1992-02-27 Menetelmä polypeptidin valmistamiseksi FI106206B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP16876690 1990-06-27
JP16876690 1990-06-27
JP9100873 1991-06-27
PCT/JP1991/000873 WO1992000325A1 (en) 1990-06-27 1991-06-27 Anticoagulant polypeptides

Publications (2)

Publication Number Publication Date
FI920889A0 true FI920889A0 (fi) 1992-02-27
FI106206B FI106206B (fi) 2000-12-15

Family

ID=15874056

Family Applications (1)

Application Number Title Priority Date Filing Date
FI920889A FI106206B (fi) 1990-06-27 1992-02-27 Menetelmä polypeptidin valmistamiseksi

Country Status (8)

Country Link
US (2) US5516659A (fi)
EP (1) EP0489180A4 (fi)
JP (1) JP3189052B2 (fi)
AU (1) AU643306B2 (fi)
CA (1) CA2065409C (fi)
FI (1) FI106206B (fi)
NO (1) NO302527B1 (fi)
WO (1) WO1992000325A1 (fi)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0816494A1 (en) * 1987-01-08 1998-01-07 Asahi Kasei Kogyo Kabushiki Kaisha DNA coding for a peptide promoting the activation of protein C by thrombin, and process for producing the same
DE69433133T2 (de) * 1993-12-17 2004-04-01 Mochida Pharmaceutical Co. Ltd. Lösliches thrombomodulin enthaltende zubereitung
US6465620B1 (en) 2000-01-21 2002-10-15 Hyseq, Inc. Methods and materials relating to novel von Willebrand/Thrombospondin-like polypeptides and polynucleotides
US20030092035A1 (en) 2000-05-04 2003-05-15 Anderson David J. Pain signaling molecules
US7691604B1 (en) 2000-05-04 2010-04-06 California Institute Of Technology MRG polypeptides and nucleic acids encoding the same
US7510845B2 (en) * 2000-05-04 2009-03-31 California Institute Of Technology Assay employing G protein-coupled receptor expressed in dorsal root ganglia
US20030152941A1 (en) * 2000-06-21 2003-08-14 Boyle Bryan J. Nucleic acids encoding novel von Willebrand/Thrombospondin factor-like polypeptides and uses of same
US7713544B2 (en) * 2000-07-28 2010-05-11 Emory University Biological component comprising artificial membrane
EP1390407B1 (en) * 2001-05-25 2005-09-07 Vlaams Interuniversitair Instituut voor Biotechnologie vzw. The lectin-like domain of thrombomodulin and its therapeutic use
JP4187141B2 (ja) * 2002-04-12 2008-11-26 興和株式会社 新規なトロンボモジュリン発現促進剤
US20040121410A1 (en) * 2002-12-20 2004-06-24 Anderson David J. Pain signaling molecules
MX2009003384A (es) * 2006-10-06 2009-04-08 Asahi Kasei Pharma Corp Agente terapeutico y/o de mejoramiento para la coagulacion intravascular diseminada.
CN101641368B (zh) 2007-03-23 2013-05-08 旭化成制药株式会社 高纯度可溶性血栓调节蛋白的制造方法
US20120165244A1 (en) * 2008-10-30 2012-06-28 Hua-Lin Wu Methods for binding lewis y antigen
CN102216326A (zh) * 2008-11-12 2011-10-12 伊莱利利公司 凝血调节蛋白变体的组合物和使用方法
JP2011178687A (ja) * 2010-02-26 2011-09-15 Kochi Univ 造血細胞移植に伴う疼痛の予防および／または治療剤
US9127089B2 (en) 2010-04-30 2015-09-08 Asahi Kasei Pharma Corporation Highly-purified soluble thrombomodulin and method for producing same
US9150844B2 (en) 2010-08-05 2015-10-06 Neeraj Maheshwari Protein fusion constructs possessing thrombolytic and anticoagulant properties
AU2012337838B2 (en) 2011-11-15 2016-04-21 Asahi Kasei Pharma Corporation Medicament for therapeutic treatment and/or improvement of sepsis
JP6124417B2 (ja) 2012-05-31 2017-05-10 学校法人近畿大学 抗癌剤に起因する末梢性神経障害性疼痛の予防及び／又は治療剤
US11497795B2 (en) 2018-09-28 2022-11-15 Asahi Kasei Pharma Corporation Medicament for mitigating conditions and/or suppressing onset of peripheral neuropathy induced by anti-malignant tumor agent
CA3116686A1 (en) 2018-10-22 2020-04-30 Asahi Kasei Pharma Corporation Medicament for therapeutic treatment and/or improvement of sepsis accompanied by coagulopathy
CN114686443B (zh) * 2020-12-31 2023-11-03 广州万孚生物技术股份有限公司 杂交瘤细胞、抗血栓调节蛋白单克隆抗体及其制备方法和应用

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60199819A (ja) * 1984-03-23 1985-10-09 Kowa Co トロンビン結合性物質およびその製法
JPH0689014B2 (ja) * 1986-01-21 1994-11-09 興和株式会社 トロンビン結合性物質およびその製法
JPS63146898A (ja) * 1986-07-15 1988-06-18 Kowa Co トロンビン結合性物質およびその製法
US5047503A (en) * 1986-07-15 1991-09-10 Kowa Company, Ltd. Thrombin-binding substance and process for its preparation
JPS6330423A (ja) * 1986-07-22 1988-02-09 Kowa Co トロンビン結合性物質およびその製法
EP0816494A1 (en) * 1987-01-08 1998-01-07 Asahi Kasei Kogyo Kabushiki Kaisha DNA coding for a peptide promoting the activation of protein C by thrombin, and process for producing the same
US4912207A (en) * 1987-05-06 1990-03-27 Washington University DNA clone of human thrombomodulin and portions thereof
DK299087D0 (da) * 1987-06-12 1987-06-12 Novo Industri As Proteins and derivatives thereof
JPH0219399A (ja) * 1988-07-05 1990-01-23 Oklahoma Medical Res Found トロンビン結合ポリピペプチド
US5202421A (en) * 1988-12-27 1993-04-13 Mochida Pharmaceutical Co., Ltd. Anticoagulant substance obtained from urine and process for the preparation thereof
US5256770A (en) * 1990-04-09 1993-10-26 Schering Ag Oxidation resistant thrombomodulin analogs
US5273962A (en) * 1990-11-30 1993-12-28 Kowa Co., Ltd. Human urinary thrombomodulin with a modified glycosaminoglycan (GAG) binding site

Also Published As

Publication number Publication date
AU8080091A (en) 1992-01-23
NO920762D0 (no) 1992-02-26
AU643306B2 (en) 1993-11-11
NO920762L (no) 1992-04-24
NO302527B1 (no) 1998-03-16
CA2065409C (en) 2002-05-14
WO1992000325A1 (en) 1992-01-09
EP0489180A4 (en) 1993-03-31
CA2065409A1 (en) 1991-12-28
FI106206B (fi) 2000-12-15
US5695964A (en) 1997-12-09
JP3189052B2 (ja) 2001-07-16
EP0489180A1 (en) 1992-06-10
US5516659A (en) 1996-05-14

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