NO915115D0 - Cytokinsynteseinhibitorfaktor, antagonister for denne og fremgangsmaater for anvendelse derav - Google Patents

Cytokinsynteseinhibitorfaktor, antagonister for denne og fremgangsmaater for anvendelse derav

Info

Publication number
NO915115D0
NO915115D0 NO1991915115A NO915115A NO915115D0 NO 915115 D0 NO915115 D0 NO 915115D0 NO 1991915115 A NO1991915115 A NO 1991915115A NO 915115 A NO915115 A NO 915115A NO 915115 D0 NO915115 D0 NO 915115D0
Authority
NO
Norway
Prior art keywords
antagonists
cytochine
procedures
synthesis inhibitor
inhibitor factor
Prior art date
Application number
NO1991915115A
Other languages
English (en)
Other versions
NO915115L (no
NO301718B1 (no
Inventor
Timothy R Mosmann
Kevin W Moore
Martha W Bond
Paulo J M Vieira
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of NO915115D0 publication Critical patent/NO915115D0/no
Publication of NO915115L publication Critical patent/NO915115L/no
Publication of NO301718B1 publication Critical patent/NO301718B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/5428—IL-10
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO915115A 1989-06-28 1991-12-27 Fremgangsmåte for fremstilling av et polypeptid med cytokinsynteseinhiberingsfaktoraktivitet NO301718B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US37266789A 1989-06-28 1989-06-28
US45395189A 1989-12-20 1989-12-20
PCT/US1990/003554 WO1991000349A1 (en) 1989-06-28 1990-06-28 Cytokine synthesis inhibitory factor, antagonists thereof, and methods of using same

Publications (3)

Publication Number Publication Date
NO915115D0 true NO915115D0 (no) 1991-12-27
NO915115L NO915115L (no) 1992-02-26
NO301718B1 NO301718B1 (no) 1997-12-01

Family

ID=27005854

Family Applications (1)

Application Number Title Priority Date Filing Date
NO915115A NO301718B1 (no) 1989-06-28 1991-12-27 Fremgangsmåte for fremstilling av et polypeptid med cytokinsynteseinhiberingsfaktoraktivitet

Country Status (22)

Country Link
EP (2) EP0405980A1 (no)
JP (1) JP2813063B2 (no)
KR (1) KR0183035B1 (no)
CN (3) CN1318589C (no)
AT (1) ATE180833T1 (no)
AU (1) AU635058B2 (no)
CA (1) CA2062763C (no)
CS (1) CS414591A3 (no)
DE (1) DE69033143T2 (no)
DK (1) DK0567450T3 (no)
ES (1) ES2132068T3 (no)
FI (1) FI107926B (no)
GR (1) GR3030404T3 (no)
HK (2) HK1040531B (no)
HU (1) HU216310B (no)
IL (1) IL94878A (no)
NO (1) NO301718B1 (no)
NZ (1) NZ234291A (no)
PT (1) PT94514B (no)
SG (1) SG52282A1 (no)
TW (1) TW218383B (no)
WO (1) WO1991000349A1 (no)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5827513A (en) * 1990-06-29 1998-10-27 Schering Corporation Methods of treating insulin-dependent diabetes mellitus by administration of IL-10
US6106823A (en) * 1991-01-16 2000-08-22 Schering Corporation Treatment of neoplastic disease with interleukin-10
ES2074879T3 (es) * 1991-01-16 1995-09-16 Schering Corp Uso de interleuquina-10 en inmunoterapia adoptiva de cancer.
AU652030B2 (en) * 1991-01-16 1994-08-11 Schering Corporation Treatment of neoplastic disease with interleukin-10
DE4122402A1 (de) * 1991-07-04 1993-01-07 Schering Ag Verwendung von interleukin 10 zur herstellung von arzneimitteln mit tumorhemmender wirksamkeit
US5833976A (en) * 1991-08-06 1998-11-10 Schering Corporation Use of interleukin-10 (IL-10) to treat endotoxin- or superantigen-induced toxicity
FI940519A0 (fi) * 1991-08-06 1994-02-04 Schering Corp Interleukiini-10-analogien tai -antagonistien käyttö endotoksiinin taisuperantigeenin indusoiman toksisuuden hoitamiseksi
US6277635B1 (en) 1992-03-04 2001-08-21 Schering Corporation Use of interleukin-10 to produce a population of suppressor cells
US6884410B1 (en) 1992-03-04 2005-04-26 Schering Corporation Methods for modulating antigen-specific immune responses
AU679908B2 (en) * 1992-03-04 1997-07-17 Schering Corporation Use of interleukin-10 to suppress graft-vs.-host disease
AU3801193A (en) * 1992-03-20 1993-10-21 Schering Corporation Use of interleukin-10 to induce the production of interleukin-1 receptor antagonist
TW243415B (no) * 1992-08-20 1995-03-21 Schering Corp
US5601815A (en) * 1992-08-21 1997-02-11 Schering Corp IL-4 and IL-10 to downregulate delayed-type hypersensitivity and cytokine expresion by T-cells
AU4856793A (en) * 1992-09-18 1994-04-12 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Restoration of immunocompetency to t helper cells in hiv infected patients
ES2131122T3 (es) * 1992-10-01 1999-07-16 Schering Corp Uso de il-10 para prevenir la diabetes mellitus dependiente de insulina.
TW381026B (en) * 1993-01-13 2000-02-01 Schering Corp Method of extracorporally activating cytolytic activity of peripheral blood mononuclear cells and pharmaceutical composition comprising the activated peripheral blood mononuclear cells
EP0681589A1 (en) * 1993-02-01 1995-11-15 Université Libre de Bruxelles Use of a pharmaceutical composition comprising an effective amount of interleukin-10, an analog and/or an agonist of interleukin-10
US5328989A (en) * 1993-03-05 1994-07-12 Schering-Plough Purification of human interleukin-10 from a cell culture medium
US5449688A (en) * 1993-03-30 1995-09-12 The United States Of America As Represented By The Department Of Health And Human Services Method of treating chronic inflammatory diseases
KR960704041A (ko) * 1993-07-26 1996-08-31 에릭 에스. 딕커 사람 인터루킨-10의 효능제 및 길항제(Agonists and antagonists of human interleukin-10)
US5650060A (en) * 1994-01-28 1997-07-22 Minnesota Mining And Manufacturing Company Ionically conductive agent, system for cathodic protection of galvanically active metals, and method and apparatus for using same
CZ1497A3 (en) 1994-07-05 1997-05-14 Steeno Res Group As Polypeptide, its use and pharmaceutical composition based thereon, a nucleotide sequence and antibody
US5770190A (en) * 1995-07-14 1998-06-23 Schering Corporation Method of treatment of acute leukemia with inteleukin-10
CN100389126C (zh) * 1995-12-13 2008-05-21 儿童医学中心公司 内皮细胞增殖抑制剂及其应用方法
AU4385696A (en) * 1996-01-18 1997-08-11 Christian Gronhoj Larsen Synthetic il-10 analogues
IL126623A0 (en) * 1996-04-17 1999-08-17 Prendergast Patrick T Pharmaceutical compositions and kits for dhea combined therapy
EP0925072A2 (en) * 1996-09-06 1999-06-30 Schering Corporation Method for lowering cholesterol levels
WO1998047516A1 (en) * 1997-04-17 1998-10-29 Prendergast Patrick T Combination therapy utilising 17-ketosteroids and interleukin inhibitors, or interleukin-10 potionally with interleukin inhibitors
US6465176B1 (en) * 1998-10-02 2002-10-15 Message Pharmaceuticals, Inc. Method for identifying compounds RNA/RNA binding protein interactions
AU5047600A (en) * 1999-05-27 2000-12-18 Schering Corporation Mammalian interleukin-10 homologs: il-d110 and il-d210
CN1981868A (zh) 2000-03-31 2007-06-20 拜奥根Idec公司 抗细胞因子抗体或拮抗剂与抗－cd20在b细胞淋巴瘤治疗中的联合应用
US8491912B2 (en) 2010-06-16 2013-07-23 Allergan, Inc. Methods of treating ocular and other diseases with Syn-134R polypeptide
WO2017160599A1 (en) 2016-03-14 2017-09-21 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Use of cd300b antagonists to treat sepsis and septic shock
US10610104B2 (en) 2016-12-07 2020-04-07 Progenity, Inc. Gastrointestinal tract detection methods, devices and systems
CA3054156A1 (en) 2017-03-30 2018-10-04 Progenity Inc. Treatment of a disease of the gastrointestinal tract with il-10 or an il-10 agonist
WO2020106757A1 (en) 2018-11-19 2020-05-28 Progenity, Inc. Ingestible device for delivery of therapeutic agent to the gastrointestinal tract
CN115666704B (zh) 2019-12-13 2025-09-26 比特比德科有限责任公司 用于将治疗剂递送至胃肠道的可摄取装置
GB202003428D0 (en) * 2020-03-10 2020-04-22 Univ Dundee IL-10 mutiens

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL78197A (en) * 1985-03-22 1991-07-18 Genentech Inc Nucleic acid encoding tgf-beta and its uses
IE62650B1 (en) * 1989-08-04 1995-02-22 David & Sons Ltd Dispensing apparatus
DK0506836T3 (da) * 1989-12-20 1994-11-28 Schering Corp BCRF1 proteiner som inhibitorer for interferon-gamma

Also Published As

Publication number Publication date
CN1317343A (zh) 2001-10-17
WO1991000349A1 (en) 1991-01-10
NO915115L (no) 1992-02-26
NZ234291A (en) 1992-11-25
GR3030404T3 (en) 1999-09-30
DK0567450T3 (da) 1999-12-13
HU216310B (hu) 1999-06-28
HK1040493A1 (en) 2002-06-14
HK1040531B (zh) 2008-01-11
HU906705D0 (en) 1992-03-30
HK1040531A1 (en) 2002-06-14
EP0567450A1 (en) 1993-11-03
HUT61048A (en) 1992-11-30
EP0567450B1 (en) 1999-06-02
JP2813063B2 (ja) 1998-10-22
NO301718B1 (no) 1997-12-01
TW218383B (no) 1994-01-01
JPH04502560A (ja) 1992-05-14
ATE180833T1 (de) 1999-06-15
CN1051393A (zh) 1991-05-15
CN1198642C (zh) 2005-04-27
ES2132068T3 (es) 1999-08-16
HK1040493B (zh) 2005-12-16
CA2062763C (en) 2010-01-05
CS414591A3 (en) 1992-12-16
FI107926B (fi) 2001-10-31
IL94878A (en) 2003-01-12
DE69033143D1 (de) 1999-07-08
EP0405980A1 (en) 1991-01-02
PT94514B (pt) 1998-02-27
KR920701437A (ko) 1992-08-11
CN1317569A (zh) 2001-10-17
IL94878A0 (en) 1991-04-15
SG52282A1 (en) 1998-09-28
AU635058B2 (en) 1993-03-11
PT94514A (pt) 1991-04-18
CN1318589C (zh) 2007-05-30
KR0183035B1 (ko) 1999-04-01
HK1008834A1 (en) 1999-05-21
FI916126A0 (fi) 1991-12-27
DE69033143T2 (de) 1999-10-21
AU6077090A (en) 1991-01-17
CA2062763A1 (en) 1990-12-29

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Legal Events

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