NO914985L - Fremgangsmaate for fremstilling av 15-nitro-tabersonin-derivater - Google Patents

Fremgangsmaate for fremstilling av 15-nitro-tabersonin-derivater

Info

Publication number
NO914985L
NO914985L NO91914985A NO914985A NO914985L NO 914985 L NO914985 L NO 914985L NO 91914985 A NO91914985 A NO 91914985A NO 914985 A NO914985 A NO 914985A NO 914985 L NO914985 L NO 914985L
Authority
NO
Norway
Prior art keywords
tabersonin
nitro
derivatives
procedure
preparation
Prior art date
Application number
NO91914985A
Other languages
English (en)
Norwegian (no)
Other versions
NO914985D0 (no
Inventor
Bela Zsadon
Margit Barta
Maria Szilasi
Tibor Keve
Janos Galambos
Viktoria Bolya
Emilia Repasi
Laszlo Szporny
Bela Kiss
Egon Karpati
Eva Palosi
Zsolt Szombathelyi
Adam Sarkadi
Aniko Gere
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of NO914985D0 publication Critical patent/NO914985D0/no
Publication of NO914985L publication Critical patent/NO914985L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/20—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
NO91914985A 1990-12-18 1991-12-17 Fremgangsmaate for fremstilling av 15-nitro-tabersonin-derivater NO914985L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU908313A HU206883B (en) 1990-12-18 1990-12-18 Process for producing new 15-nitro-2-beta-, 3-beta-dihydro- and 15-nitro-2-beta, 3-beta-, 6,7-tetrahydro-tabersonin derivatives and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
NO914985D0 NO914985D0 (no) 1991-12-17
NO914985L true NO914985L (no) 1992-06-19

Family

ID=10972531

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91914985A NO914985L (no) 1990-12-18 1991-12-17 Fremgangsmaate for fremstilling av 15-nitro-tabersonin-derivater

Country Status (16)

Country Link
US (1) US5204355A (hu)
EP (1) EP0491549B1 (hu)
JP (1) JPH04334380A (hu)
KR (1) KR920012079A (hu)
CN (1) CN1063690A (hu)
AU (1) AU8972591A (hu)
CA (1) CA2057829A1 (hu)
DE (1) DE69118340T2 (hu)
FI (1) FI915930A (hu)
HU (1) HU206883B (hu)
IE (1) IE914198A1 (hu)
IL (1) IL100393A0 (hu)
NO (1) NO914985L (hu)
PL (1) PL292813A1 (hu)
YU (1) YU195291A (hu)
ZA (1) ZA919912B (hu)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7205404B1 (en) * 1999-03-05 2007-04-17 Metabasis Therapeutics, Inc. Phosphorus-containing prodrugs
CN102558178B (zh) * 2012-01-09 2015-06-03 中国科学院昆明植物研究所 水甘草碱(tabersonine)衍生物及其药物组合物和制备方法与用途
EP3623364A1 (en) 2014-02-13 2020-03-18 Ligand Pharmaceuticals, Inc. Prodrug compounds and their uses
CN106687118A (zh) 2014-07-02 2017-05-17 配体药物公司 前药化合物及其用途
JP2021509907A (ja) 2018-01-09 2021-04-08 リガンド・ファーマシューティカルズ・インコーポレイテッド アセタール化合物およびその治療的使用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2358147A1 (fr) * 1976-07-13 1978-02-10 Parcor Aspidospermidines
JPS62234054A (ja) * 1985-12-16 1987-10-14 Ono Pharmaceut Co Ltd ３−フエノキシ（またはフエニルチオ）シクロペンタンカルボニルアミノ酸誘導体およびそれらを有効成分として含有する脳浮腫治療剤

Also Published As

Publication number Publication date
CA2057829A1 (en) 1992-06-19
ZA919912B (en) 1992-10-28
US5204355A (en) 1993-04-20
IL100393A0 (en) 1992-09-06
FI915930A (fi) 1992-06-19
FI915930A0 (fi) 1991-12-17
HU206883B (en) 1993-01-28
HUT59681A (en) 1992-06-29
HU908313D0 (en) 1991-07-29
JPH04334380A (ja) 1992-11-20
NO914985D0 (no) 1991-12-17
CN1063690A (zh) 1992-08-19
EP0491549A1 (en) 1992-06-24
DE69118340D1 (de) 1996-05-02
EP0491549B1 (en) 1996-03-27
YU195291A (sh) 1994-04-05
PL292813A1 (en) 1992-12-14
KR920012079A (ko) 1992-07-25
IE914198A1 (en) 1992-07-01
AU8972591A (en) 1992-06-25
DE69118340T2 (de) 1996-08-29

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