NO914135D0 - Bakterioklorofyll-a-derivater for fotodynamisk terapi - Google Patents

Bakterioklorofyll-a-derivater for fotodynamisk terapi

Info

Publication number
NO914135D0
NO914135D0 NO914135A NO914135A NO914135D0 NO 914135 D0 NO914135 D0 NO 914135D0 NO 914135 A NO914135 A NO 914135A NO 914135 A NO914135 A NO 914135A NO 914135 D0 NO914135 D0 NO 914135D0
Authority
NO
Norway
Prior art keywords
compounds
photodynamic therapy
image
substrates
irradiation
Prior art date
Application number
NO914135A
Other languages
English (en)
Other versions
NO914135L (no
Inventor
Thomas J Dougherty
Original Assignee
Health Research Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Health Research Inc filed Critical Health Research Inc
Publication of NO914135D0 publication Critical patent/NO914135D0/no
Publication of NO914135L publication Critical patent/NO914135L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/22—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A61K41/0071—PDT with porphyrins having exactly 20 ring atoms, i.e. based on the non-expanded tetrapyrrolic ring system, e.g. bacteriochlorin, chlorin-e6, or phthalocyanines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
NO91914135A 1989-04-21 1991-10-21 Bakterioklorofyll-a-derivater for fotodynamisk terapi NO914135L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/341,591 US5171741A (en) 1989-04-21 1989-04-21 Bacteriochlorophyll-a derivatives useful in photodynamic therapy
PCT/US1990/001680 WO1990012573A1 (en) 1989-04-21 1990-03-29 Bacteriochlorophyll-a derivatives useful in photodynamic therapy

Publications (2)

Publication Number Publication Date
NO914135D0 true NO914135D0 (no) 1991-10-21
NO914135L NO914135L (no) 1991-11-20

Family

ID=23338198

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91914135A NO914135L (no) 1989-04-21 1991-10-21 Bakterioklorofyll-a-derivater for fotodynamisk terapi

Country Status (11)

Country Link
US (1) US5171741A (no)
EP (1) EP0468997B1 (no)
JP (1) JP3118253B2 (no)
AT (1) ATE149831T1 (no)
AU (1) AU645010B2 (no)
CA (1) CA2053268C (no)
DE (1) DE69030180T2 (no)
DK (1) DK0468997T3 (no)
ES (1) ES2098262T3 (no)
NO (1) NO914135L (no)
WO (1) WO1990012573A1 (no)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39094E1 (en) 1988-07-20 2006-05-09 Health Research, Inc. Pyropheophorbides and their use in photodynamic therapy
USRE38994E1 (en) 1988-07-20 2006-02-28 Health Research, Inc. Pyropheophorbides conjugates and their use in photodynamic therapy
US5563262A (en) * 1991-03-28 1996-10-08 University Of Toledo Diels alder adducts of vinyl porphyrins
US5587394A (en) * 1991-03-28 1996-12-24 The University Of Toledo Production and use of diels alder adducts of vinyl porphyrins, of metal complexes thereof, and of compositions containing such adducts and complexes
US5179120A (en) * 1991-06-28 1993-01-12 Cytopharm, Inc. Porphycene compounds for photodynamic therapy
DE4121876A1 (de) * 1991-07-02 1993-01-14 Scheer Hugo Modifizierte bakteriochlorophylle, verfahren zu ihrer herstellung und ihre verwendung
IL102645A (en) * 1992-07-26 1998-02-22 Yeda Res & Dev Chlorophyll and bacteriochlorophyll derivatives, their preparation and pharmaceutical compositions comprising them
US5817830A (en) * 1992-08-14 1998-10-06 Trustees Of The University Of Pennsylvania Pyrrolic compounds
US5783306A (en) * 1992-08-14 1998-07-21 Trustees Of The University Of Pennsylvania Hyperpolarizable compounds and devices fabricated therefrom
US5493017A (en) * 1992-08-14 1996-02-20 The Trustees Of The University Of Pennsylvania Ring-metalated porphyrins
US5371199B1 (en) * 1992-08-14 1995-12-26 Univ Pennsylvania Substituted porphyrins porphyrin-containing polymers and synthetic methods therefor
US5599924A (en) * 1992-08-14 1997-02-04 Trustees Of The University Of Pennsylvania Electron-deficient porphyrins and processes and intermediates for preparing same
US5660181A (en) * 1994-12-12 1997-08-26 Physical Optics Corporation Hybrid neural network and multiple fiber probe for in-depth 3-D mapping
US5882328A (en) * 1995-01-13 1999-03-16 Qlt Phototherapeutics, Inc. Method to prevent transplant rejection
IL116126A0 (en) * 1995-11-24 1996-01-31 Yeda Res & Dev Process for the preparation of bacteriochlorophyllis some novel compounds of this type and pharmaceutical compositions comprising them
HU228208B1 (en) * 1998-12-09 2013-01-28 Yeda Res & Dev Palladium-substituted bacteriochlorophyll derivatives and use thereof
US20020022032A1 (en) * 1999-04-23 2002-02-21 Curry Patrick Mark Immuno-adjuvant PDT treatment of metastatic tumors
US7045117B2 (en) * 1999-12-01 2006-05-16 Yeda Research And Development Co. Ltd. Method for tumor diagnosis comprising administering of palladium-substituted bacteriochlorophyll derivatives
IL133253A0 (en) * 1999-12-01 2001-04-30 Yeda Res & Dev Chlorophyll and bacteriochlorophyll esters, their preparation and pharmaceutical compositions comprising them
US7097826B2 (en) 1999-12-23 2006-08-29 Health Research, Inc. Chlorin and bacteriochlorin-based difunctional aminophenyl DTPA and N2S2 conjugates for MR contrast media and radiopharmaceuticals
US6534040B2 (en) 1999-12-23 2003-03-18 Health Research, Inc. Chlorin and bacteriochlorin-based aminophenyl DTPA and N2S2 conjugates for MR contrast media and radiopharmaceuticals
US7897140B2 (en) 1999-12-23 2011-03-01 Health Research, Inc. Multi DTPA conjugated tetrapyrollic compounds for phototherapeutic contrast agents
US7078014B2 (en) * 1999-12-23 2006-07-18 Health Research, Inc. Method for using chlorin and bacteriochlorin-based aminophenyl DTPA and N2S2 conjugates for MR contrast media and radiopharmaceuticals
AU2001258117A1 (en) 2000-05-08 2001-11-20 The University Of British Columbia Supports for photosensitizer formulations
US6624187B1 (en) 2000-06-12 2003-09-23 Health Research, Inc. Long wave length absorbing bacteriochlorin alkyl ether analogs
WO2004002476A2 (en) 2002-06-27 2004-01-08 Health Research, Inc. Fluorinated chlorin and bacteriochlorin photosensitizers for photodynamic therapy
US7053210B2 (en) 2002-07-02 2006-05-30 Health Research, Inc. Efficient synthesis of pyropheophorbide a and its derivatives
IL152900A0 (en) 2002-11-17 2003-06-24 Yeda Res & Dev Water-soluble bacteriochlorophyll derivatives and their pharmaceutical uses
KR100484206B1 (ko) * 2003-01-16 2005-04-20 주식회사 테크노마트 포르피린 화합물
US20050101582A1 (en) 2003-11-12 2005-05-12 Allergan, Inc. Compositions and methods for treating a posterior segment of an eye
US20070224278A1 (en) 2003-11-12 2007-09-27 Lyons Robert T Low immunogenicity corticosteroid compositions
CA2553381C (en) 2004-01-20 2011-03-22 Allergan, Inc. Compositions for localized therapy of the eye, comprising preferably triamcinolone acetonide and hyaluronic acid
BRPI0510485A (pt) 2004-04-30 2007-11-13 Allergan Inc implantes inibidores de tirosina cinase intravìtreos biodegradáveis
US8425929B2 (en) 2004-04-30 2013-04-23 Allergan, Inc. Sustained release intraocular implants and methods for preventing retinal dysfunction
US8119154B2 (en) 2004-04-30 2012-02-21 Allergan, Inc. Sustained release intraocular implants and related methods
US20050244500A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Intravitreal implants in conjuction with photodynamic therapy to improve vision
US8591885B2 (en) 2004-04-30 2013-11-26 Allergan, Inc. Carbonic anhydrase inhibitor sustained release intraocular drug delivery systems
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US8722097B2 (en) 2004-04-30 2014-05-13 Allergan, Inc. Oil-in-water method for making polymeric implants containing a hypotensive lipid
US8673341B2 (en) 2004-04-30 2014-03-18 Allergan, Inc. Intraocular pressure reduction with intracameral bimatoprost implants
US8147865B2 (en) 2004-04-30 2012-04-03 Allergan, Inc. Steroid-containing sustained release intraocular implants and related methods
US7771742B2 (en) 2004-04-30 2010-08-10 Allergan, Inc. Sustained release intraocular implants containing tyrosine kinase inhibitors and related methods
US7993634B2 (en) 2004-04-30 2011-08-09 Allergan, Inc. Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US20050244458A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular neuropathies
US20050244465A1 (en) * 2004-04-30 2005-11-03 Allergan, Inc. Drug delivery systems and methods for treatment of an eye
US8455656B2 (en) 2004-04-30 2013-06-04 Allergan, Inc. Kinase inhibitors
US20050244463A1 (en) 2004-04-30 2005-11-03 Allergan, Inc. Sustained release intraocular implants and methods for treating ocular vasculopathies
US9498457B2 (en) 2004-04-30 2016-11-22 Allergan, Inc. Hypotensive prostamide-containing biodegradable intraocular implants and related implants
WO2006020979A2 (en) * 2004-08-13 2006-02-23 Yale University Factor vii conjugates for selectively treating neovascularization disorders
WO2006089122A2 (en) * 2005-02-18 2006-08-24 North Carolina State University De novo synthesis of bacteriochlorins
US20060223750A1 (en) * 2005-04-01 2006-10-05 Allergan, Inc. Agents and methods for enhancing photodynamic therapy
US8969415B2 (en) 2006-12-01 2015-03-03 Allergan, Inc. Intraocular drug delivery systems
LT5567B (lt) 2008-08-06 2009-04-27 Vilniaus Universitetas Maisto ir su maistu susietų paviršių nukenksminimo būdas
US20110092961A1 (en) * 2008-08-13 2011-04-21 Searete Llc Artificial cells
GB0819594D0 (en) 2008-10-24 2008-12-03 Univ Coimbrra Process
US8829020B2 (en) 2009-07-16 2014-09-09 Mallinckrodt Llc Compounds and compositions for use in phototherapy and in treatment of ocular neovascular disease and cancers
JP5982287B2 (ja) 2009-11-09 2016-08-31 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ 発毛を刺激する組成物および方法
CA2788824C (en) 2010-02-04 2019-03-12 Morphotek, Inc. Chlorotoxin polypeptides and conjugates and uses thereof
WO2013003507A1 (en) 2011-06-27 2013-01-03 Morphotek, Inc. Multifunctional agents
US20140308204A1 (en) 2011-10-25 2014-10-16 Memorial Sloan Kettering Cancer Center Free psa antibodies as diagnostics, prognostics and therapeutics for prostate cancer
AU2013334102B2 (en) 2012-10-26 2018-08-16 Memorial Sloan-Kettering Cancer Center Modulators of resistant androgen receptor
RU2641021C2 (ru) 2013-02-15 2018-01-17 Аллерган, Инк. Имплантат для пролонгированной доставки лекарственного средства
CA2934524C (en) 2013-12-23 2022-02-15 Memorial Sloan-Kettering Cancer Center Methods and compositions for treating cancer using peptide nucleic acid-based agents
AU2018235945A1 (en) 2017-03-14 2019-10-17 Ohio State Innovation Foundation Methods and compositions related to a tissue factor-targeting IgG3 immunoconjugates

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4649151A (en) * 1982-09-27 1987-03-10 Health Research, Inc. Drugs comprising porphyrins
US4727027A (en) * 1983-05-02 1988-02-23 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
JPS60981A (ja) * 1983-06-17 1985-01-07 Matsushita Electric Ind Co Ltd 印字装置
IT1160148B (it) * 1983-12-19 1987-03-04 Cselt Centro Studi Lab Telecom Dispositivo per la verifica del parlatore
CA1311239C (en) * 1985-10-23 1992-12-08 Isao Sakata Porphyrin derivatives, and their production and use
JPS634805A (ja) * 1986-06-24 1988-01-09 Mitsui Eng & Shipbuild Co Ltd 低温熱源利用液体分離・濃縮・脱水装置

Also Published As

Publication number Publication date
NO914135L (no) 1991-11-20
US5171741A (en) 1992-12-15
ES2098262T3 (es) 1997-05-01
CA2053268C (en) 2001-01-30
EP0468997A4 (en) 1992-04-22
DE69030180D1 (en) 1997-04-17
AU645010B2 (en) 1994-01-06
CA2053268A1 (en) 1990-10-22
AU5413090A (en) 1990-11-16
JP3118253B2 (ja) 2000-12-18
WO1990012573A1 (en) 1990-11-01
EP0468997A1 (en) 1992-02-05
ATE149831T1 (de) 1997-03-15
JPH04507236A (ja) 1992-12-17
EP0468997B1 (en) 1997-03-12
DK0468997T3 (da) 1997-04-28
DE69030180T2 (de) 1997-06-19

Similar Documents

Publication Publication Date Title
NO914135D0 (no) Bakterioklorofyll-a-derivater for fotodynamisk terapi
DE3650265T2 (de) Makrolide Antibiotika und Verfahren zu deren Herstellung.
RU94043771A (ru) Замещенные бензимидазольные соединения, способ лечения, фармацевтическая композиция и способ получения бензимидазольных соединений
MX9205792A (es) Derivados novedosos de asa-androstan 178-substituidos
HK1077847A1 (en) Natural antitumor or antiviral substances and use of the same
KR900017582A (ko) 항암 항생물질 mi43-37f11, 그 제조방법 및 그 용도
JP2003521457A5 (no)
AU551678B2 (en) Antiviral alpha alpha dialkyl adamantylethylamines
ATE115859T1 (de) Neue pharmazeutische präparate sowie neue lactosylverbindungen und ihre herstellung.
KR950014110A (ko) 사이클로프로판 유도체 및 이를 포함하는 항바이러스제
BE900477A (fr) Derives de aminoethyl-2-penem, leur procede de preparation et les preparations pharmaceutiques les contenant.
ES2051765T3 (es) 13 alfa-alquilgon-delta9(11)-en-5,10-epoxidos.
SE8803143D0 (sv) Alternativa energisubstrat
RU2000117270A (ru) Производные цитотоксичных алкалоидов, включающих асмарины a и b, выделенные из губки
KR970702869A (ko) 항종양성 인돌로피롤로카르바졸 유도체(antitumor indolopyprolocarbazole derivative)
IT1229846B (it) Esteri di catecolammine.
TH83125B (th) อนุพันธ์เนยูรามินิคแอซิดการเตรียมของมันและการใช้ประโยชน์ของมันทางการแพทย์
BG49444A1 (en) Acylureidoamynotiasolylni derivatives and method for their preparation
TH13242EX (th) สารประกอบใหม่ชื่อว่า "เลอุสโทรดัคซิน" การเตรียมและประโยชน์ในการใช้รักษาของสารประกอบเหล่านี้
RU95105584A (ru) Производные анеллированного дигидропиридина и их соли с физиологически переносимыми кислотами или комплексообразователями
KR910000774A (ko) 앙골라마이신 유도체, 그의 제조방법 및 용도
RU94037754A (ru) 3-(2'-нафтоилметилен)-пиперазинон-2 и 1-n-фенил-3-фенацилиденпиперазинон-2, проявляющие противовоспалительную активность