NO912874D0 - Fremgangsmaate for fremstilling av nye carbocykliske analoger av visse nucleosider. - Google Patents

Fremgangsmaate for fremstilling av nye carbocykliske analoger av visse nucleosider.

Info

Publication number
NO912874D0
NO912874D0 NO912874A NO912874A NO912874D0 NO 912874 D0 NO912874 D0 NO 912874D0 NO 912874 A NO912874 A NO 912874A NO 912874 A NO912874 A NO 912874A NO 912874 D0 NO912874 D0 NO 912874D0
Authority
NO
Norway
Prior art keywords
procedure
preparation
certain nucleosides
carbocyclic analogs
new carbocyclic
Prior art date
Application number
NO912874A
Other languages
English (en)
Other versions
NO912874L (no
Inventor
Serge Halazy
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of NO912874D0 publication Critical patent/NO912874D0/no
Publication of NO912874L publication Critical patent/NO912874L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509—Six-membered rings
    • C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO91912874A 1990-07-24 1991-07-23 Fremgangsmaate for fremstilling av nye carbocykliske analoger av visse nucleosider. NO912874L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP90402129A EP0468119A1 (en) 1990-07-24 1990-07-24 Novel carbocyclic analogs of certain nucleosides

Publications (2)

Publication Number Publication Date
NO912874D0 true NO912874D0 (no) 1991-07-23
NO912874L NO912874L (no) 1992-01-27

Family

ID=8205742

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91912874A NO912874L (no) 1990-07-24 1991-07-23 Fremgangsmaate for fremstilling av nye carbocykliske analoger av visse nucleosider.

Country Status (13)

Country Link
EP (2) EP0468119A1 (no)
JP (1) JPH04330086A (no)
KR (1) KR920002623A (no)
CN (1) CN1059528A (no)
AU (1) AU8110991A (no)
CA (1) CA2047390A1 (no)
FI (1) FI913533A (no)
HU (1) HUT59152A (no)
IE (1) IE912587A1 (no)
IL (1) IL98918A0 (no)
NO (1) NO912874L (no)
PT (1) PT98425A (no)
ZA (1) ZA915657B (no)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5744600A (en) * 1988-11-14 1998-04-28 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic Phosphonomethoxy carbocyclic nucleosides and nucleotides
DK0465297T3 (da) * 1990-07-04 1996-02-19 Merrell Pharma Inc 9-Purinylphosphonsyre-derivater
DK0671918T3 (da) * 1992-12-03 1997-06-16 Merrell Pharma Inc Præparater indeholdende acyclovir-lignende forbindelser og 2-vinylsubstituerede nucleosidanaloge til behandling af virusinfektioner
GB9226879D0 (en) * 1992-12-23 1993-02-17 Iaf Biochem Int Anti-viral compounds
US6005107A (en) 1992-12-23 1999-12-21 Biochem Pharma, Inc. Antiviral compounds
US6444656B1 (en) 1992-12-23 2002-09-03 Biochem Pharma, Inc. Antiviral phosphonate nucleotides
US5654286A (en) * 1993-05-12 1997-08-05 Hostetler; Karl Y. Nucleotides for topical treatment of psoriasis, and methods for using same
EP0719274A1 (en) * 1993-09-17 1996-07-03 Gilead Sciences, Inc. Method for dosing therapeutic compounds
US5656745A (en) * 1993-09-17 1997-08-12 Gilead Sciences, Inc. Nucleotide analogs
US5798340A (en) * 1993-09-17 1998-08-25 Gilead Sciences, Inc. Nucleotide analogs
WO1996001638A1 (en) * 1994-07-11 1996-01-25 Hoechst Marion Roussel, Inc. Method of treating a neoplastic disease state by conjunctive therapy with 2'-fluoromethylidene derivatives and radiation or chemotherapy
US5977061A (en) * 1995-04-21 1999-11-02 Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic N6 - substituted nucleotide analagues and their use
IL118626A0 (en) * 1996-06-11 1996-10-16 Xtl Biopharmaceuticals Limited Anti HBV antibody
CA2263286A1 (en) 1996-08-13 1998-02-19 Naoko Ueda Phosphonate nucleotide compound
GB9821058D0 (en) * 1998-09-28 1998-11-18 Univ Cardiff Chemical compound
GB9903091D0 (en) * 1999-02-12 1999-03-31 Glaxo Group Ltd Therapeutic nucleoside compound
WO2003002580A1 (en) 2001-06-29 2003-01-09 Institute Of Organic Chemistry And Biochemistry Ofthe Academy Of Sciences Of The Czech Republic 6-`2-(phosphonomethoxy)alkoxy pyrimidine derivatives having antiviral activity
EA014685B1 (ru) * 2003-04-25 2010-12-30 Джилид Сайэнс, Инк. Фосфонатсодержащие антивирусные соединения (варианты) и фармацевтическая композиция на их основе
WO2004111064A1 (en) 2003-06-16 2004-12-23 Institute Of Organic Chemistry And Biochemistry, Academy Of Sciences Of The Czech Republic Pyrimidine compounds having phosphonate groups as antiviral nucleotide analogs
AR051922A1 (es) 2004-07-27 2007-02-21 Gilead Sciences Inc Analogos de fosfonatos de compuestos inhibidores de hiv
TWI444384B (zh) 2008-02-20 2014-07-11 Gilead Sciences Inc 核苷酸類似物及其在治療惡性腫瘤上的用途
AP3347A (en) 2008-07-08 2015-07-31 Gilead Sciences Inc Salts of HIV inhibitor compounds
CN102395590A (zh) 2009-02-06 2012-03-28 Rfs制药公司 用于治疗癌症和病毒感染的嘌呤核苷单磷酸酯前药
WO2018067424A1 (en) * 2016-10-03 2018-04-12 Arcus Biosciences, Inc. Inhibitors of adenosine 5'-nucleotidase
SI3661937T1 (sl) 2017-08-01 2021-11-30 Gilead Sciences, Inc. Kristalinične oblike etil((S)-((((2R,5R)-5-(6-amino-9H-purin-9-IL)-4- fluoro-2,5-dihidrofuran-2-IL)oksi)metil)(fenoksi)fosforil)-L-alaninata (GS-9131) za zdravljenje virusnih okužb

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2001715C (en) * 1988-11-14 1999-12-28 Muzammil M. Mansuri Carbocyclic nucleosides and nucleotides

Also Published As

Publication number Publication date
EP0468119A1 (en) 1992-01-29
JPH04330086A (ja) 1992-11-18
EP0468866A1 (en) 1992-01-29
IL98918A0 (en) 1992-07-15
KR920002623A (ko) 1992-02-28
FI913533A0 (fi) 1991-07-23
NO912874L (no) 1992-01-27
ZA915657B (en) 1992-05-27
CN1059528A (zh) 1992-03-18
CA2047390A1 (en) 1992-01-25
HUT59152A (en) 1992-04-28
PT98425A (pt) 1992-05-29
FI913533A (fi) 1992-01-25
IE912587A1 (en) 1992-01-29
AU8110991A (en) 1992-01-30
HU912470D0 (en) 1991-12-30

Similar Documents

Publication Publication Date Title
NO912874D0 (no) Fremgangsmaate for fremstilling av nye carbocykliske analoger av visse nucleosider.
NO873091L (no) Fremgangsmaate for fremstilling av nye benzimidazolderivater.
NO913625D0 (no) Fremgangsmaate for fremstilling av nye carbocykliske adenosinanaloger.
NO904059L (no) Fremgangsmaate for fremstilling av nye substituerte isokinoliner.
AR228011A1 (es) Procedimiento para la preparacion de derivados sustituidos de 2,5,5,8a-tetrametil-1,2,3,4,4a,5,6,7,8,8a-decahidronaftaleno-1-spiro-2'-(4',6',7'-sustituido-2',3'-dihidrobenzofurano)
IT7851705A0 (it) Procedimento per la purificazione di lattici polimerici
IT7823757A0 (it) Procedimento per la stabilizzazione di profumi.
IT1095367B (it) Procedimento per la separazione di olefine
NO913391D0 (no) Fremgangsmaate for fremstilling av nye hetrazepinoide syreamider.
NO901813L (no) Fremgangsmaate for fremstilling av nye tieno-triazolo-diazepin-derivater.
IT1096156B (it) Procedimento per la preparazione di 1-azolil-3,3-dimetil-1-fenoss-butan-2-oni
IT8622467A0 (it) Procedimento per la sintesi di perfluoroalcadieni.
IT8020124A0 (it) Procedimento per la separazione di orto-cloronitrobenzene.
NO892977L (no) Fremgangsmaate for fremstilling av nye s-adenosylmethionin-derivater.
NO911118D0 (no) Fremgangsmaate for fremstilling av nye 8-sulfamylmethylen-2-amino-tetraliner.
IT1097328B (it) Procedimento per la preparazione di uretani aromatici
NO904069L (no) Fremgangsmaate for fremstilling av nye alkanofenoner.
NO891381D0 (no) Fremgangsmaate for fremstilling av nye fluorfosfonatnukleotidderivater.
IT7851938A0 (it) Procedimento per l'isolamento di gomme
NO872393L (no) Fremgangsmaate for fremstilling av nye aralkylimidazolderivater.
IT1094983B (it) Procedimento per la preparazione di 3,5 di alogeno-aniline
IT1102532B (it) Procedimento per la separazione di pirrolidone-2 da polipirrolidone
IT7849064A0 (it) Procedimento per la produzione di organopolisilossani modificati reticolati
NO871721L (no) Fremgangsmaate for fremstilling av nye ergolenderivater.
IT8021231A0 (it) Procedimento per la preparazione di 2-amminopirazine sostituite.