FI913533A0 - Nya karbocykliska analoger av vissa nukleosider. - Google Patents
Nya karbocykliska analoger av vissa nukleosider.Info
- Publication number
- FI913533A0 FI913533A0 FI913533A FI913533A FI913533A0 FI 913533 A0 FI913533 A0 FI 913533A0 FI 913533 A FI913533 A FI 913533A FI 913533 A FI913533 A FI 913533A FI 913533 A0 FI913533 A0 FI 913533A0
- Authority
- FI
- Finland
- Prior art keywords
- nucleosider
- vissa
- analoger
- nya
- carbocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP90402129A EP0468119A1 (en) | 1990-07-24 | 1990-07-24 | Novel carbocyclic analogs of certain nucleosides |
Publications (2)
Publication Number | Publication Date |
---|---|
FI913533A0 true FI913533A0 (fi) | 1991-07-23 |
FI913533A FI913533A (fi) | 1992-01-25 |
Family
ID=8205742
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI913533A FI913533A (fi) | 1990-07-24 | 1991-07-23 | Nya karbocykliska analoger av vissa nukleosider. |
Country Status (13)
Country | Link |
---|---|
EP (2) | EP0468119A1 (fi) |
JP (1) | JPH04330086A (fi) |
KR (1) | KR920002623A (fi) |
CN (1) | CN1059528A (fi) |
AU (1) | AU8110991A (fi) |
CA (1) | CA2047390A1 (fi) |
FI (1) | FI913533A (fi) |
HU (1) | HUT59152A (fi) |
IE (1) | IE912587A1 (fi) |
IL (1) | IL98918A0 (fi) |
NO (1) | NO912874L (fi) |
PT (1) | PT98425A (fi) |
ZA (1) | ZA915657B (fi) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5744600A (en) * | 1988-11-14 | 1998-04-28 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic | Phosphonomethoxy carbocyclic nucleosides and nucleotides |
DE69116750T2 (de) * | 1990-07-04 | 1996-11-14 | Merrell Dow Pharma | 9-Purinyl-Phosphonsäurederivate |
DE69311135T2 (de) * | 1992-12-03 | 1997-09-25 | Merrell Pharma Inc | Zubereitungen, die acyclovir-ähnliche verbindungen und 2'-vinylsubstituierte nukleosidanaloge enthalten, zur behandlung viraler infektionen |
GB9226879D0 (en) * | 1992-12-23 | 1993-02-17 | Iaf Biochem Int | Anti-viral compounds |
US6005107A (en) | 1992-12-23 | 1999-12-21 | Biochem Pharma, Inc. | Antiviral compounds |
US6444656B1 (en) | 1992-12-23 | 2002-09-03 | Biochem Pharma, Inc. | Antiviral phosphonate nucleotides |
US5654286A (en) * | 1993-05-12 | 1997-08-05 | Hostetler; Karl Y. | Nucleotides for topical treatment of psoriasis, and methods for using same |
KR100386685B1 (ko) * | 1993-09-17 | 2003-12-31 | 길리애드 사이언시즈, 인코포레이티드 | 뉴클레오타이드동족체류 |
US5798340A (en) * | 1993-09-17 | 1998-08-25 | Gilead Sciences, Inc. | Nucleotide analogs |
US5656745A (en) * | 1993-09-17 | 1997-08-12 | Gilead Sciences, Inc. | Nucleotide analogs |
WO1996001638A1 (en) * | 1994-07-11 | 1996-01-25 | Hoechst Marion Roussel, Inc. | Method of treating a neoplastic disease state by conjunctive therapy with 2'-fluoromethylidene derivatives and radiation or chemotherapy |
US5977061A (en) * | 1995-04-21 | 1999-11-02 | Institute Of Organic Chemistry And Biochemistry Of The Academy Of Sciences Of The Czech Republic | N6 - substituted nucleotide analagues and their use |
IL118626A0 (en) | 1996-06-11 | 1996-10-16 | Xtl Biopharmaceuticals Limited | Anti HBV antibody |
DE69716924T2 (de) * | 1996-08-13 | 2003-03-20 | Mitsubishi Chem Corp | Phosphonat-nukleotid-verbindungen |
GB9821058D0 (en) | 1998-09-28 | 1998-11-18 | Univ Cardiff | Chemical compound |
GB9903091D0 (en) * | 1999-02-12 | 1999-03-31 | Glaxo Group Ltd | Therapeutic nucleoside compound |
EA006020B1 (ru) | 2001-06-29 | 2005-08-25 | Инститьют Оф Оргэник Кемистри Энд Байокемистри Оф Зе Экэдеми Оф Сайэнс Оф Зе Чек Рипаблик | Производные 6-[2-(фосфонометокси)алкокси]пиримидинов, обладающие антивирусной активностью, способ их получения (варианты) и способ лечения вирусной инфекции |
ATE490788T1 (de) * | 2003-04-25 | 2010-12-15 | Gilead Sciences Inc | Antivirale phosphonate analoge |
DK1644389T3 (da) | 2003-06-16 | 2011-05-09 | Acad Of Science Czech Republic | Pyrinidinforbindelser med phosphonatgrupper som antivirale nukleotidanaloger |
DE602005027466D1 (de) | 2004-07-27 | 2011-05-26 | Gilead Sciences Inc | Nukleosid phosphonat konjugate als anti hiv mittel |
TWI444384B (zh) | 2008-02-20 | 2014-07-11 | Gilead Sciences Inc | 核苷酸類似物及其在治療惡性腫瘤上的用途 |
US8658617B2 (en) | 2008-07-08 | 2014-02-25 | Gilead Sciences, Inc. | Salts of HIV inhibitor compounds |
JP2012517443A (ja) | 2009-02-06 | 2012-08-02 | アールエフエス ファーマ,エルエルシー | 癌及びウイルス感染の治療のためのプリンヌクレオシド一リン酸プロドラッグ |
CN110049767B (zh) * | 2016-10-03 | 2023-04-04 | 艾库斯生物科学有限公司 | 腺苷5′-核苷酸酶的抑制剂 |
ES2892402T3 (es) | 2017-08-01 | 2022-02-04 | Gilead Sciences Inc | Formas cristalinas de ((S)-((((2R,5R)-5-(6-amino-9H-purin-9-il)-4-fluoro-2,5-dihidrofuran-2-il)oxi)metil)(fenoxi)fosforil)-L-alaninato de etilo para tratar infecciones virales |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2001715C (en) * | 1988-11-14 | 1999-12-28 | Muzammil M. Mansuri | Carbocyclic nucleosides and nucleotides |
-
1990
- 1990-07-24 EP EP90402129A patent/EP0468119A1/en not_active Withdrawn
-
1991
- 1991-07-18 ZA ZA915657A patent/ZA915657B/xx unknown
- 1991-07-18 AU AU81109/91A patent/AU8110991A/en not_active Abandoned
- 1991-07-18 CA CA002047390A patent/CA2047390A1/en not_active Abandoned
- 1991-07-19 EP EP91402022A patent/EP0468866A1/en not_active Withdrawn
- 1991-07-22 IL IL98918A patent/IL98918A0/xx unknown
- 1991-07-23 KR KR1019910012578A patent/KR920002623A/ko not_active Application Discontinuation
- 1991-07-23 HU HU912470A patent/HUT59152A/hu unknown
- 1991-07-23 FI FI913533A patent/FI913533A/fi unknown
- 1991-07-23 NO NO91912874A patent/NO912874L/no unknown
- 1991-07-23 CN CN91105787A patent/CN1059528A/zh active Pending
- 1991-07-23 PT PT98425A patent/PT98425A/pt not_active Application Discontinuation
- 1991-07-23 IE IE258791A patent/IE912587A1/en unknown
- 1991-07-24 JP JP3206243A patent/JPH04330086A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
HUT59152A (en) | 1992-04-28 |
PT98425A (pt) | 1992-05-29 |
ZA915657B (en) | 1992-05-27 |
EP0468866A1 (en) | 1992-01-29 |
JPH04330086A (ja) | 1992-11-18 |
EP0468119A1 (en) | 1992-01-29 |
CA2047390A1 (en) | 1992-01-25 |
KR920002623A (ko) | 1992-02-28 |
IE912587A1 (en) | 1992-01-29 |
IL98918A0 (en) | 1992-07-15 |
CN1059528A (zh) | 1992-03-18 |
NO912874D0 (no) | 1991-07-23 |
FI913533A (fi) | 1992-01-25 |
NO912874L (no) | 1992-01-27 |
HU912470D0 (en) | 1991-12-30 |
AU8110991A (en) | 1992-01-30 |
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