NO905037D0 - Kaskadepolymerbundne kompleksdannere, komplekser og konjugater derav, fremgangsmaate for fremstilling av disse, samtfarmasoeytiske midler som inneholder disse. - Google Patents
Kaskadepolymerbundne kompleksdannere, komplekser og konjugater derav, fremgangsmaate for fremstilling av disse, samtfarmasoeytiske midler som inneholder disse.Info
- Publication number
- NO905037D0 NO905037D0 NO905037A NO905037A NO905037D0 NO 905037 D0 NO905037 D0 NO 905037D0 NO 905037 A NO905037 A NO 905037A NO 905037 A NO905037 A NO 905037A NO 905037 D0 NO905037 D0 NO 905037D0
- Authority
- NO
- Norway
- Prior art keywords
- complexes
- conjugates
- procedure
- preparation
- pharmaceutical agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G85/00—General processes for preparing compounds provided for in this subclass
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/0002—General or multifunctional contrast agents, e.g. chelated agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/04—X-ray contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/085—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier conjugated systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
- A61K49/08—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations characterised by the carrier
- A61K49/10—Organic compounds
- A61K49/12—Macromolecular compounds
- A61K49/124—Macromolecular compounds dendrimers, dendrons, hyperbranched compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/06—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules
- A61K51/065—Macromolecular compounds, carriers being organic macromolecular compounds, i.e. organic oligomeric, polymeric, dendrimeric molecules conjugates with carriers being macromolecules
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G83/00—Macromolecular compounds not provided for in groups C08G2/00 - C08G81/00
- C08G83/002—Dendritic macromolecules
- C08G83/003—Dendrimers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Radiology & Medical Imaging (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Polymers & Plastics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Compounds Of Unknown Constitution (AREA)
- Steroid Compounds (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3938992A DE3938992A1 (de) | 1989-11-21 | 1989-11-21 | Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
Publications (4)
Publication Number | Publication Date |
---|---|
NO905037D0 true NO905037D0 (no) | 1990-11-21 |
NO905037L NO905037L (no) | 1991-05-22 |
NO178032B NO178032B (no) | 1995-10-02 |
NO178032C NO178032C (no) | 1996-01-10 |
Family
ID=6394147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO905037A NO178032C (no) | 1989-11-21 | 1990-11-21 | Kaskadepolymerer, kontrastmiddel inneholdende slike, fremgangsmåte for fremstilling av kaskadepolymerene og anvendelse av disse |
Country Status (19)
Country | Link |
---|---|
US (10) | US5364614A (no) |
EP (1) | EP0430863B2 (no) |
JP (2) | JP3179092B2 (no) |
KR (1) | KR100202796B1 (no) |
AT (1) | ATE122698T1 (no) |
AU (1) | AU684453C (no) |
CA (1) | CA2030472C (no) |
DE (2) | DE3938992A1 (no) |
DK (1) | DK0430863T4 (no) |
ES (1) | ES2073006T5 (no) |
FI (1) | FI107931B (no) |
GR (1) | GR3031629T3 (no) |
HU (1) | HUT56121A (no) |
IE (1) | IE69317B1 (no) |
IL (1) | IL96434A (no) |
NO (1) | NO178032C (no) |
NZ (1) | NZ236162A (no) |
PT (1) | PT95944B (no) |
ZA (1) | ZA909352B (no) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5560929A (en) * | 1986-08-18 | 1996-10-01 | The Dow Chemical Company | Structured copolymers and their use as absorbents, gels and carriers of metal ions |
US5527524A (en) * | 1986-08-18 | 1996-06-18 | The Dow Chemical Company | Dense star polymer conjugates |
US5334371A (en) * | 1988-07-20 | 1994-08-02 | Schering Aktiengesellschaft | Marcocyclic polyaza bicyclo compounds containing 5 or 6 membered rings, and method for MRI |
DE4001655A1 (de) * | 1990-01-18 | 1991-07-25 | Schering Ag | 6-ring enthaltende makrocyclische tetraaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
US5914095A (en) * | 1989-04-07 | 1999-06-22 | Salutar, Inc. | Polychelants containg amide bonds |
DE3938992A1 (de) | 1989-11-21 | 1991-05-23 | Schering Ag | Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
DE4115789A1 (de) * | 1991-05-10 | 1992-11-12 | Schering Ag | Makrocyclische polymer-komplexbildner, deren komplexe, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
AU3246893A (en) * | 1991-12-10 | 1993-07-19 | Dow Chemical Company, The | Bicycloazamacrocyclophosphonic acid, conjugates, contrast agents and preparation |
US5428139A (en) * | 1991-12-10 | 1995-06-27 | The Dow Chemical Company | Bicyclopolyazamacrocyclophosphonic acid complexes for use as radiopharmaceuticals |
US5739294A (en) * | 1991-12-10 | 1998-04-14 | The Dow Chemical Company | Bicyclopol yazamacrocyclophosphonic acid complexes for use as contrast agents |
WO1994026313A1 (en) * | 1993-05-06 | 1994-11-24 | The Dow Chemical Company | Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as contrast agents |
US5817292A (en) * | 1992-10-14 | 1998-10-06 | Nycomed Imaging As | MR imaging compositions and methods |
CA2146990A1 (en) * | 1992-10-14 | 1994-04-28 | Robert A. Snow | Chelating polymers |
EP0664713B1 (en) * | 1992-10-14 | 2000-01-19 | Nycomed Imaging As | Therapeutic and diagnostic imaging compositions and methods |
US6203775B1 (en) * | 1993-03-19 | 2001-03-20 | The General Hospital Corporation | Chelating polymers for labeling of proteins |
US5428156A (en) * | 1993-04-02 | 1995-06-27 | Associated Universities, Inc. | Synthesis of macrocyclic polyaminocarboxylates and their use for preparing stable radiometal antibody immunoconjugates for therapy, spect and pet imaging |
US5482698A (en) * | 1993-04-22 | 1996-01-09 | Immunomedics, Inc. | Detection and therapy of lesions with biotin/avidin polymer conjugates |
WO1994026315A1 (en) * | 1993-05-06 | 1994-11-24 | The Dow Chemical Company | Bicyclopolyazamacrocyclocarboxylic acid complexes, their conjugates, processes for their preparation, and use as radiopharmaceuticals |
AU6953294A (en) * | 1993-05-20 | 1994-12-20 | Regents Of The University Of California, The | Macromolecular contrast media for mr imaging |
US5534241A (en) * | 1993-07-23 | 1996-07-09 | Torchilin; Vladimir P. | Amphipathic polychelating compounds and methods of use |
DE4344464A1 (de) * | 1993-12-22 | 1995-06-29 | Schering Ag | Kaskadenpolymere mit Iodaromaten |
DE4344460A1 (de) * | 1993-12-22 | 1995-06-29 | Schering Ag | Metallkomplexe von dendrimeren Makromolekülen, diese enthaltende diagnostische Mittel sowie Verfahren zur Herstellung der Komplexe und Mittel |
US5831087A (en) * | 1994-03-02 | 1998-11-03 | Hoechst Celanese Corp. | Macrocyclic imide compounds |
GB9404208D0 (en) * | 1994-03-04 | 1994-04-20 | Nycomed Salutar Inc | Chelants |
IL128775A (en) * | 1994-03-07 | 2001-05-20 | Dow Chemical Co | A preparation containing a dendritic polymer in a complex with at least one unit of biological reaction sub |
GB9407812D0 (en) * | 1994-04-20 | 1994-06-15 | Nycomed Salutar Inc | Compounds |
US5958372A (en) * | 1994-06-28 | 1999-09-28 | Nycomed Imaging As | Low viscosity chelating polymers for diagnostic imaging |
DE4425857A1 (de) * | 1994-07-07 | 1996-01-11 | Schering Ag | Kaskaden-Polymer-Komplexe, Verfahren zur ihrer Herstellung und diese enthaltende pharmazeutische Mittel |
DE4426438A1 (de) * | 1994-07-26 | 1996-02-01 | Schering Ag | Verwendung von Chelaten als Röntgenkontrastmittel |
US6207826B1 (en) | 1995-03-27 | 2001-03-27 | Isis Pharmaceuticals, Inc. | Macrocyclic compounds having nitrogen-containing linkages |
GB9504910D0 (en) * | 1995-03-10 | 1995-04-26 | Nycomed Imaging As | Compounds |
US6107482A (en) | 1995-03-27 | 2000-08-22 | Isis Pharmaceuticals, Inc. | Nitrogenous macrocyclic compounds |
DE19518222A1 (de) * | 1995-05-11 | 1996-11-14 | Schering Ag | Verwendung von polymeren Kontrastmittel mittleren Molekulargewichts zur Differenzierung von benignen und malignen Tumoren mittels moderner bildgebender Verfahren |
DE19521945A1 (de) * | 1995-06-12 | 1996-12-19 | Schering Ag | Kaskadenpolymere mit Iodaromaten |
DE19525924A1 (de) * | 1995-07-04 | 1997-01-09 | Schering Ag | Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel |
US6166200A (en) * | 1995-07-04 | 2000-12-26 | Schering Aktiengesellschaft | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes |
DE19549286A1 (de) * | 1995-12-22 | 1997-06-26 | Schering Ag | Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel |
AU726034B2 (en) * | 1995-12-22 | 2000-10-26 | Schering Aktiengesellschaft | Cascade polymer complexes, process for their production and pharmaceutical agents that contain the latter |
US5874061A (en) * | 1995-12-22 | 1999-02-23 | Schering Aktiengesellschaft | Cascade polymer complexes, process for their production and pharmaceutical agents containing said complexes |
DE19652387A1 (de) * | 1996-12-04 | 1998-06-10 | Schering Ag | Macrocyclische Metallkomplexcarbonsäuren, ihre Verwendung sowie Verfahren zu ihrer Herstellung |
JP4233117B2 (ja) * | 1997-01-13 | 2009-03-04 | 住友化学株式会社 | 樹枝状ポリマーのナノコンポジット |
WO1998056427A1 (fr) * | 1997-06-12 | 1998-12-17 | Mitsubishi Chemical Corporation | Agent de contrast |
EP0885616A1 (de) * | 1997-06-20 | 1998-12-23 | Schering Aktiengesellschaft | Verwendung von intravenösen Kontrastmitteln sowie Vorrichtungen für die Projektionsmammographie |
US5849337A (en) * | 1997-06-27 | 1998-12-15 | Gusty Winds Corporation | Method of enhancing magnesium absorption and prevention of atherosclerosis |
DE19744003B4 (de) * | 1997-09-26 | 2004-07-08 | Schering Ag | Kontrastmittel für das Infarkt- und Nekroseimaging |
DE19758118A1 (de) * | 1997-12-17 | 1999-07-01 | Schering Ag | Polyrotaxane |
US6113880A (en) * | 1997-12-17 | 2000-09-05 | Schering Aktiengesellschaft | Polyrotaxane derivatives for x-ray and nuclear magnetic resonance imaging |
US6549798B2 (en) * | 2001-02-07 | 2003-04-15 | Epix Medical, Inc. | Magnetic resonance angiography data |
EP1401430A4 (en) * | 2001-05-31 | 2005-10-19 | Miravant Pharm Inc | SUBSTITUTED PORPHYRIN AND AZAPORPHYRIN DERIVATIVES AND USE IN PHOTODYNAMIC THERAPY, RADIOIMAGING, AND MRI DIAGNOSIS |
ITMI20011518A1 (it) * | 2001-07-17 | 2003-01-17 | Bracco Imaging Spa | Leganti azotati multidentati capaci di complessare ioni metallici e loro uso in diagnostica e in terapia |
US7893223B2 (en) * | 2001-07-17 | 2011-02-22 | Bracco Imaging S.P.A. | Multidentate AZA ligands able to complex metal ions and the use thereof in diagnostics and therapy |
TWI221406B (en) * | 2001-07-30 | 2004-10-01 | Epix Medical Inc | Systems and methods for targeted magnetic resonance imaging of the vascular system |
US20040034223A1 (en) * | 2002-02-07 | 2004-02-19 | Covalent Partners, Llc. | Amphiphilic molecular modules and constructs based thereon |
EP1481268A4 (en) * | 2002-02-07 | 2005-06-29 | Covalent Partners Llc | NANOFILM AND MEMBRANE COMPOSITIONS |
US20040106741A1 (en) * | 2002-09-17 | 2004-06-03 | Kriesel Joshua W. | Nanofilm compositions with polymeric components |
WO2004054623A1 (en) * | 2002-12-16 | 2004-07-01 | Amersham Health As | Magnetic resonance imaging method and compounds for use in the method |
US7648678B2 (en) | 2002-12-20 | 2010-01-19 | Dako Denmark A/S | Method and system for pretreatment of tissue slides |
US20040137551A1 (en) * | 2003-01-13 | 2004-07-15 | Markovic Nenad S. | Cervical acid phosphatase - papanicolaou (CAP-PAP) test kit, method and accesories, processes for producing and using the same |
AR047692A1 (es) * | 2003-07-10 | 2006-02-08 | Epix Medical Inc | Imagenes de blancos estacionarios |
WO2005028432A1 (en) * | 2003-09-12 | 2005-03-31 | Dendritic Nanotechnologies, Inc. | Hyperbranched (pamam) polymers via a one pot process |
US6960418B2 (en) * | 2003-10-23 | 2005-11-01 | Samsung Electronics Co., Ltd. | Organophotoreceptor with charge transport material with two N,N,N-trisubstituted-amino groups |
EP1541568A1 (de) * | 2003-12-09 | 2005-06-15 | Deutsches Wollforschungsinstitut an der Rheinisch-Westfälischen Technischen Hochschule Aachen e.V. | Reaktive cyclische Carbonate und Harnstoffe zur Modifizierung von Biomolekülen, Polymeren und Oberflächen |
US7199268B2 (en) | 2003-12-16 | 2007-04-03 | Schering Aktiengesellschaft | Process for the production of dendritic trimesic acid triamides |
EP1855567B1 (en) * | 2005-03-01 | 2015-09-23 | Haworth, Inc. | Tilt control mechanism for a chair |
US9603941B2 (en) * | 2006-01-24 | 2017-03-28 | Minghui Chai | Method of preparing dendritic drugs |
JP5518465B2 (ja) | 2006-03-14 | 2014-06-11 | マリンクロッド エルエルシー | テトラアザ大員環誘導体の金属錯体 |
WO2007137418A1 (en) | 2006-05-27 | 2007-12-06 | Winnik Mitchell A | Polymer backbone element tags |
FR2906253A1 (fr) * | 2006-09-22 | 2008-03-28 | Biosphere Medical Sa | Nouveaux materiaux polymeres bio-compatibles, leur procede d'obtention et leurs utilisations, notamment en imagerie medicale par resonnance magnetique |
DE102007002726A1 (de) | 2007-01-18 | 2008-07-31 | Bayer Schering Pharma Aktiengesellschaft | Neue Kaskaden-Polymer-Komplexe, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel |
KR20100027101A (ko) | 2007-04-11 | 2010-03-10 | 오레곤 헬스 앤드 사이언스 유니버시티 | 심장에서 섬유증을 비침윤적으로 및 정량적으로 검출하는 방법 및 장치 |
US20110038805A1 (en) * | 2008-04-18 | 2011-02-17 | Andreas Meijer | Compounds comprising paramagnetic chelates arranged around a central core and their use in magneto resonance imaging and spectroscopy |
KR101334780B1 (ko) | 2010-08-13 | 2013-12-02 | 한국생명공학연구원 | 요오드를 함유한 방사형상의 고분자 화합물, 이의 제조방법 및 이를 포함하는 ct용 조영제 조성물 |
CN105658310A (zh) | 2013-09-13 | 2016-06-08 | 斯坦福大学托管董事会 | 使用质量标签和次级离子质谱术的组织复用成像 |
EP3274719B1 (en) | 2015-03-25 | 2021-02-24 | The Board of Trustees of the Leland Stanford Junior University | Single cell analysis using secondary ion mass spectrometry |
WO2018107173A1 (en) * | 2016-12-09 | 2018-06-14 | Vanderbilt University | Glutamine transport inhibitors and methods for treating cancer |
EP3595594B1 (en) | 2017-03-15 | 2024-09-18 | Merit Medical Systems, Inc. | Transluminal stents |
EP4231973A4 (en) | 2020-10-26 | 2024-10-02 | Merit Medical Systems Inc | HELICAL THREAD ESOPHAGEAL STENT PROSTHESES |
Family Cites Families (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4036945A (en) | 1976-05-03 | 1977-07-19 | The Massachusetts General Hospital | Composition and method for determining the size and location of myocardial infarcts |
US4071478A (en) * | 1976-06-07 | 1978-01-31 | Merck & Co., Inc. | Controlled partially cross-linked 3,3-ionenes |
DE2803528C2 (de) * | 1977-03-09 | 1984-10-18 | Tabushi, Iwao, Kyoto | Schwermetallionen-Adsorbens und dessen Verwendung zum Adsorbieren von Schwermetallionen |
US4331647A (en) | 1980-03-03 | 1982-05-25 | Goldenberg Milton David | Tumor localization and therapy with labeled antibody fragments specific to tumor-associated markers |
JPS5779551A (en) | 1980-11-06 | 1982-05-18 | Nec Corp | Information transfer device |
US4647447A (en) * | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
DE3129906C3 (de) * | 1981-07-24 | 1996-12-19 | Schering Ag | Paramagnetische Komplexsalze, deren Herstellung und Mittel zur Verwendung bei der NMR-Diagnostik |
US4957939A (en) * | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
US4507466A (en) | 1983-01-07 | 1985-03-26 | The Dow Chemical Corporation | Dense star polymers having core, core branches, terminal groups |
NL194579C (nl) | 1983-01-21 | 2002-08-05 | Schering Ag | Diagnostisch middel. |
US4587329A (en) * | 1984-08-17 | 1986-05-06 | The Dow Chemical Company | Dense star polymers having two dimensional molecular diameter |
US5188816A (en) * | 1984-10-18 | 1993-02-23 | Board Of Regents, The University Of Texas System | Using polyazamacrocyclic compounds for intracellular measurement of metal ions using MRS |
US4639365A (en) * | 1984-10-18 | 1987-01-27 | The Board Of Regents, The University Of Texas System | Gadolinium chelates as NMR contrast agents |
CA1317937C (en) * | 1984-10-18 | 1993-05-18 | A. Dean Sherry | Gadolinium chelates with carboxymethyl derivatives of polyazamacrocycles as nmr contrast agents |
US4678667A (en) | 1985-07-02 | 1987-07-07 | 501 Regents of the University of California | Macrocyclic bifunctional chelating agents |
US4871779A (en) | 1985-12-23 | 1989-10-03 | The Dow Chemical Company | Ion exchange/chelation resins containing dense star polymers having ion exchange or chelate capabilities |
DE3772785D1 (de) | 1986-01-23 | 1991-10-17 | Squibb & Sons Inc | 1-substituiertes-4,7,10-triscarboxymethyl-1,4,7,10-tetraazacyclododecan und analoga. |
US4885363A (en) * | 1987-04-24 | 1989-12-05 | E. R. Squibb & Sons, Inc. | 1-substituted-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs |
GB8603537D0 (en) * | 1986-02-13 | 1986-03-19 | Parker D | Conjugate compound |
US4694064A (en) | 1986-02-28 | 1987-09-15 | The Dow Chemical Company | Rod-shaped dendrimer |
US5560929A (en) * | 1986-08-18 | 1996-10-01 | The Dow Chemical Company | Structured copolymers and their use as absorbents, gels and carriers of metal ions |
ES2054678T5 (es) * | 1986-08-18 | 1997-09-16 | Dow Chemical Co | Conjugados estrella. |
US5527524A (en) * | 1986-08-18 | 1996-06-18 | The Dow Chemical Company | Dense star polymer conjugates |
US5338532A (en) * | 1986-08-18 | 1994-08-16 | The Dow Chemical Company | Starburst conjugates |
DE3701665A1 (de) | 1987-01-19 | 1988-07-28 | Schering Ag | Polymer-komplexe, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel |
US5057302A (en) | 1987-02-13 | 1991-10-15 | Abbott Laboratories | Bifunctional chelating agents |
WO1989000557A1 (en) * | 1987-07-16 | 1989-01-26 | Cockbain, Julian, Roderick, Michaelson | Aminopolycarboxylic acids and derivatives thereof |
DE3728525A1 (de) * | 1987-08-24 | 1989-03-16 | Schering Ag | Mehrkernige substituierte komplexbildner, komplexe und komplexsalze, verfahren zu deren herstellung und diese enthaltende pharmazeutische mittel |
DE3806795A1 (de) * | 1988-02-29 | 1989-09-07 | Schering Ag | Polymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
NZ229700A (en) * | 1988-06-24 | 1993-01-27 | Dow Chemical Co | Tetraazacyclododecane derivatives containing a linker/spacer moiety capable of forming antibody conjugates; complexes with radionuclides and conjugates of such compounds and complexes with antibodies or antibody fragments |
US5554748A (en) | 1989-04-07 | 1996-09-10 | Nycomed Salutar, Inc. | Adducts of macrocyclic chelants |
US5364613A (en) * | 1989-04-07 | 1994-11-15 | Sieving Paul F | Polychelants containing macrocyclic chelant moieties |
US5136096A (en) * | 1989-08-31 | 1992-08-04 | University Of South Florida | Multifunctional synthons as used in the preparation of cascade polymers or unimolecular micelles |
DE3938992A1 (de) * | 1989-11-21 | 1991-05-23 | Schering Ag | Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
US5188806A (en) * | 1991-01-04 | 1993-02-23 | Degussa Ag | Method and apparatus for producing carbon black |
US5057696A (en) * | 1991-01-25 | 1991-10-15 | Wind Harvest Co., Inc. | Vertical windmill with omnidirectional diffusion |
US5154853A (en) * | 1991-02-19 | 1992-10-13 | University Of South Florida | Unimolecular micelles and method of making the same |
JPH066237U (ja) * | 1992-06-29 | 1994-01-25 | セントラル硝子株式会社 | ガラス板用パレット |
IL128775A (en) * | 1994-03-07 | 2001-05-20 | Dow Chemical Co | A preparation containing a dendritic polymer in a complex with at least one unit of biological reaction sub |
-
1989
- 1989-11-21 DE DE3938992A patent/DE3938992A1/de not_active Withdrawn
-
1990
- 1990-11-19 ES ES90730017T patent/ES2073006T5/es not_active Expired - Lifetime
- 1990-11-19 EP EP90730017A patent/EP0430863B2/de not_active Expired - Lifetime
- 1990-11-19 AT AT90730017T patent/ATE122698T1/de not_active IP Right Cessation
- 1990-11-19 DK DK90730017T patent/DK0430863T4/da active
- 1990-11-19 DE DE59009093T patent/DE59009093D1/de not_active Expired - Fee Related
- 1990-11-20 HU HU907217A patent/HUT56121A/hu unknown
- 1990-11-20 NZ NZ236162A patent/NZ236162A/xx unknown
- 1990-11-21 KR KR1019900018949A patent/KR100202796B1/ko not_active IP Right Cessation
- 1990-11-21 ZA ZA909352A patent/ZA909352B/xx unknown
- 1990-11-21 US US07/617,077 patent/US5364614A/en not_active Expired - Lifetime
- 1990-11-21 JP JP31444090A patent/JP3179092B2/ja not_active Expired - Fee Related
- 1990-11-21 CA CA002030472A patent/CA2030472C/en not_active Expired - Fee Related
- 1990-11-21 IE IE419990A patent/IE69317B1/en not_active IP Right Cessation
- 1990-11-21 NO NO905037A patent/NO178032C/no unknown
- 1990-11-21 IL IL9643490A patent/IL96434A/en not_active IP Right Cessation
- 1990-11-21 FI FI905744A patent/FI107931B/fi not_active IP Right Cessation
- 1990-11-21 PT PT95944A patent/PT95944B/pt not_active IP Right Cessation
- 1990-11-21 AU AU66859/90A patent/AU684453C/en not_active Ceased
-
1994
- 1994-12-02 US US08/353,390 patent/US5650136A/en not_active Expired - Fee Related
-
1996
- 1996-11-04 US US08/743,535 patent/US5911971A/en not_active Expired - Fee Related
-
1998
- 1998-09-17 US US09/156,047 patent/US6054117A/en not_active Expired - Fee Related
- 1998-09-17 US US09/156,048 patent/US6183724B1/en not_active Expired - Fee Related
-
1999
- 1999-10-15 GR GR990402638T patent/GR3031629T3/el unknown
-
2000
- 2000-02-22 US US09/510,363 patent/US6193950B1/en not_active Expired - Fee Related
- 2000-04-28 JP JP2000130116A patent/JP2000355593A/ja active Pending
- 2000-07-28 US US09/628,179 patent/US6299859B1/en not_active Expired - Fee Related
-
2001
- 2001-10-11 US US09/973,836 patent/US6576222B2/en not_active Expired - Fee Related
-
2002
- 2002-12-11 US US10/316,094 patent/US6855309B2/en not_active Expired - Fee Related
-
2004
- 2004-09-30 US US10/953,582 patent/US7208139B2/en not_active Expired - Fee Related
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO905037D0 (no) | Kaskadepolymerbundne kompleksdannere, komplekser og konjugater derav, fremgangsmaate for fremstilling av disse, samtfarmasoeytiske midler som inneholder disse. | |
NO890832D0 (no) | Polymerbundne kompleksdannere, deres komplekser og konjugater, fremgangsmaater for fremstilling av disse, og farmasoeytiske midler inneholdende disse. | |
IL89657A0 (en) | Mesotetraphenylporphyrin complex derivatives,process for the preparation thereof and pharmaceutical compositions containing the same | |
NO172238C (no) | Porfyrinkompleksforbindelser og diagnostiske midler inneholdende slike | |
NO173390C (no) | Analogifremgangsm}te for fremstilling av terapeutisk virksomme 1,2-bis(aminometyl)-cyklobutan-platinakomplekser | |
HRP920573B1 (en) | Process for the preparation of 1,2 bis(aminomethyl)cyclobutane-platinum complexes |