NO904431L - Fremgangsmaate for fremstilling av fibrinogenreseptor-antagonister. - Google Patents

Fremgangsmaate for fremstilling av fibrinogenreseptor-antagonister.

Info

Publication number
NO904431L
NO904431L NO90904431A NO904431A NO904431L NO 904431 L NO904431 L NO 904431L NO 90904431 A NO90904431 A NO 90904431A NO 904431 A NO904431 A NO 904431A NO 904431 L NO904431 L NO 904431L
Authority
NO
Norway
Prior art keywords
fibrinogene
procedure
preparation
receptor antagonists
chem
Prior art date
Application number
NO90904431A
Other languages
English (en)
Norwegian (no)
Other versions
NO904431D0 (no
Inventor
Ruth F Nutt
Daniel F Veber
Stephen F Brady
Mark E Duggan
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23669678&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO904431(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of NO904431D0 publication Critical patent/NO904431D0/no
Publication of NO904431L publication Critical patent/NO904431L/no

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B60—VEHICLES IN GENERAL
    • B60D—VEHICLE CONNECTIONS
    • B60D1/00—Traction couplings; Hitches; Draw-gear; Towing devices
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/75—Fibrinogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1016—Tetrapeptides with the first amino acid being neutral and aromatic or cycloaliphatic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Transportation (AREA)
  • Mechanical Engineering (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Materials For Medical Uses (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO90904431A 1989-10-13 1990-10-12 Fremgangsmaate for fremstilling av fibrinogenreseptor-antagonister. NO904431L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42122489A 1989-10-13 1989-10-13

Publications (2)

Publication Number Publication Date
NO904431D0 NO904431D0 (no) 1990-10-12
NO904431L true NO904431L (no) 1991-04-15

Family

ID=23669678

Family Applications (1)

Application Number Title Priority Date Filing Date
NO90904431A NO904431L (no) 1989-10-13 1990-10-12 Fremgangsmaate for fremstilling av fibrinogenreseptor-antagonister.

Country Status (16)

Country Link
EP (1) EP0422938B1 (xx)
JP (1) JP2914582B2 (xx)
KR (1) KR910007704A (xx)
AT (1) ATE118783T1 (xx)
AU (1) AU634294B2 (xx)
CA (1) CA2027315A1 (xx)
DE (1) DE69017138T2 (xx)
DK (1) DK0422938T3 (xx)
ES (1) ES2068345T3 (xx)
FI (1) FI905022A0 (xx)
IE (1) IE65197B1 (xx)
IL (1) IL95917A (xx)
NO (1) NO904431L (xx)
NZ (1) NZ235563A (xx)
PT (1) PT95582B (xx)
ZA (1) ZA908156B (xx)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5843897A (en) * 1989-06-16 1998-12-01 Cor Therapeutics, Inc. Platelet aggregation inhibitors
US5795868A (en) * 1989-06-16 1998-08-18 Cor Therapeutics, Inc. Platelet aggregation inhibitors
NZ235564A (en) * 1989-10-13 1993-10-26 Merck & Co Inc Fibrinogen receptor antagonist and pharmaceutical compositions
US5643872A (en) * 1989-10-23 1997-07-01 Smithkline Beecham Corporation Cyclic anti-aggregatory peptides
US5561220A (en) * 1991-02-08 1996-10-01 Diatech, Inc. Technetium-99m labeled peptides for imaging inflammation
US5830856A (en) * 1991-02-08 1998-11-03 Diatide, Inc. Radiolabeled compounds for thrombus imaging
WO1992013572A1 (en) * 1991-02-08 1992-08-20 Diatech, Inc. TECHNETIUM-99m LABELED POLYPEPTIDES FOR IMAGING
US6107459A (en) * 1991-02-08 2000-08-22 Diatide, Inc. Technetium-99m labeled peptides for diagnostic imaging
US6019958A (en) * 1991-02-08 2000-02-01 Diatide, Inc. Technetium-99m labeled peptides for imaging inflammation
US5736122A (en) * 1991-02-08 1998-04-07 Diatide, Inc. Technetium-99m labeled peptides for thrombus imaging
US5645815A (en) * 1991-02-08 1997-07-08 Diatide, Inc. Radiolabled compounds for thrombus imaging
IL103252A (en) 1991-09-30 1997-03-18 Du Pont Merck Pharma CYCLIC COMPOUNDS USEFUL AS INHIBITORS OF PLATELET GLYCOPROTEIN IIb/IIIa AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
US5635477A (en) * 1991-09-30 1997-06-03 The Dupont Merck Pharmaceutical Company Cyclic compounds useful as inhibitors of platelet glycoprotein IIB/IIIA
AU3064892A (en) * 1991-11-07 1993-06-07 University Of Southern California Compositions and methods for preventing adhesion formation
US5968476A (en) * 1992-05-21 1999-10-19 Diatide, Inc. Technetium-99m labeled peptides for thrombus imaging
ATE222264T1 (de) * 1992-10-02 2002-08-15 Diatide Inc Multimerische mehrzweckwirkstoffe gegen thrombose
JPH08503217A (ja) * 1992-11-18 1996-04-09 ザ・デュポン・メルク・ファーマシュウティカル・カンパニー 血小板糖タンパク質▲ＩＩ▼ｂ／▲ＩＩＩ▼ａの阻害剤として有用な複素環式環により結合された環状化合物
WO1994022911A2 (en) * 1993-03-29 1994-10-13 The Du Pont Merck Pharmaceutical Company A PROCESS AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS CONTAINING Nα-METHYLARGININE
CA2363780C (en) * 1993-04-08 2003-01-07 Diatide, Inc. Radiolabeled compounds for thrombus imaging
JPH10502349A (ja) * 1994-06-29 1998-03-03 テキサス・バイオテクノロジー・コーポレイシヨン インテグリンα▲下４▼β▲下１▼のＶＣＡＭ−１またはフィブロネクチンへの結合を阻害する方法
GB9524630D0 (en) * 1994-12-24 1996-01-31 Zeneca Ltd Chemical compounds
US6521211B1 (en) 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
WO1997002289A1 (en) * 1995-07-06 1997-01-23 Zeneca Limited Peptide inhibitors of fibronectine
GB9613112D0 (en) 1996-06-21 1996-08-28 Zeneca Ltd Chemical compounds
US6120751A (en) 1997-03-21 2000-09-19 Imarx Pharmaceutical Corp. Charged lipids and uses for the same
US6548047B1 (en) 1997-09-15 2003-04-15 Bristol-Myers Squibb Medical Imaging, Inc. Thermal preactivation of gaseous precursor filled compositions
AP1224A (en) 1998-03-19 2003-11-14 Bristol Myers Squibb Co Biphasic controlled release delivery system for high solubility pharmaceuticals and method.
JP4753403B2 (ja) * 1998-04-16 2011-08-24 エンサイシブ・フアーマシユーテイカルズ，インコーポレイテツド インテグリンのそのレセプターへの結合を阻害する化合物
US6808698B1 (en) 1999-03-26 2004-10-26 Bristol-Myers Squibb Pharma Company Method for localization of blood clots
US6972296B2 (en) 1999-05-07 2005-12-06 Encysive Pharmaceuticals Inc. Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
US6723711B2 (en) 1999-05-07 2004-04-20 Texas Biotechnology Corporation Propanoic acid derivatives that inhibit the binding of integrins to their receptors
US6685914B1 (en) 1999-09-13 2004-02-03 Bristol-Myers Squibb Pharma Company Macrocyclic chelants for metallopharmaceuticals
US6435397B2 (en) 2000-04-18 2002-08-20 Progressive Tool & Industries Co. Robotic turntable
US7319149B2 (en) 2003-06-13 2008-01-15 Bristol-Myers Squibb Pharma Company Chelants and macrocyclic metal complex radiopharmaceuticals thereof
US7317104B2 (en) 2003-06-13 2008-01-08 Bristol-Myers Squibb Pharma Company Chelants and macrocyclic metal complex radiopharmaceuticals thereof
CA2804926C (en) 2010-07-09 2019-01-08 James Trinca Green Combination immediate/delayed release delivery system for short half-life pharmaceuticals including remogliflozin
US10875875B2 (en) 2017-04-26 2020-12-29 Aviara Pharmaceuticals, Inc. Propionic acid derivatives and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0275748B1 (fr) * 1986-12-15 1992-08-19 Institut National De La Sante Et De La Recherche Medicale (Inserm) Nouveaux dérivés peptidiques et leur application notamment en thérapeutique
DK0527736T3 (da) * 1990-05-18 1997-10-20 Hoechst Ag Isoxazol-4-carboxylsyreamider og hydroxyalkyliden-cyanoacetamider, lægemidler indeholdende disse forbindelser og anvendelsen af disse lægemidler.

Also Published As

Publication number Publication date
KR910007704A (ko) 1991-05-30
IE903665A1 (en) 1991-04-24
PT95582B (pt) 1999-02-26
JP2914582B2 (ja) 1999-07-05
EP0422938B1 (en) 1995-02-22
DE69017138D1 (de) 1995-03-30
DK0422938T3 (da) 1995-05-01
IL95917A0 (en) 1991-07-18
NO904431D0 (no) 1990-10-12
EP0422938A1 (en) 1991-04-17
FI905022A0 (fi) 1990-10-12
AU6457390A (en) 1991-04-18
ATE118783T1 (de) 1995-03-15
IL95917A (en) 1998-02-08
AU634294B2 (en) 1993-02-18
IE65197B1 (en) 1995-10-04
ES2068345T3 (es) 1995-04-16
PT95582A (pt) 1991-09-13
DE69017138T2 (de) 1995-09-28
NZ235563A (en) 1993-04-28
ZA908156B (en) 1991-07-31
JPH03173897A (ja) 1991-07-29
CA2027315A1 (en) 1991-04-14

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