NO901385D0 - Karbonatderivater av eserolin, fremgangsmaate for fremstilling derav og deres anvendelse som medikamenter. - Google Patents

Karbonatderivater av eserolin, fremgangsmaate for fremstilling derav og deres anvendelse som medikamenter.

Info

Publication number
NO901385D0
NO901385D0 NO901385A NO901385A NO901385D0 NO 901385 D0 NO901385 D0 NO 901385D0 NO 901385 A NO901385 A NO 901385A NO 901385 A NO901385 A NO 901385A NO 901385 D0 NO901385 D0 NO 901385D0
Authority
NO
Norway
Prior art keywords
eserolin
medicines
procedures
preparing
carbonate derivatives
Prior art date
Application number
NO901385A
Other languages
English (en)
Other versions
NO173995C (no
NO901385L (no
NO173995B (no
Inventor
Edward J Glamkowski
Yulin Chiang
Barbara E Kurys
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Publication of NO901385D0 publication Critical patent/NO901385D0/no
Publication of NO901385L publication Critical patent/NO901385L/no
Publication of NO173995B publication Critical patent/NO173995B/no
Publication of NO173995C publication Critical patent/NO173995C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO901385A 1989-03-27 1990-03-26 Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrrolo(2,3b)indolderivater NO173995C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/329,171 US4971992A (en) 1989-03-27 1989-03-27 Carbonate derivatives of eseroline

Publications (4)

Publication Number Publication Date
NO901385D0 true NO901385D0 (no) 1990-03-26
NO901385L NO901385L (no) 1990-09-28
NO173995B NO173995B (no) 1993-11-22
NO173995C NO173995C (no) 1994-03-02

Family

ID=23284183

Family Applications (1)

Application Number Title Priority Date Filing Date
NO901385A NO173995C (no) 1989-03-27 1990-03-26 Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrrolo(2,3b)indolderivater

Country Status (18)

Country Link
US (1) US4971992A (no)
EP (1) EP0389984B1 (no)
JP (1) JPH0737458B2 (no)
KR (1) KR0163049B1 (no)
AT (1) ATE124044T1 (no)
AU (1) AU621208B2 (no)
CA (1) CA2013087C (no)
DE (1) DE69020205T2 (no)
DK (1) DK0389984T3 (no)
ES (1) ES2075081T3 (no)
FI (1) FI92932C (no)
HU (1) HU204053B (no)
IE (1) IE67449B1 (no)
IL (1) IL93895A (no)
NO (1) NO173995C (no)
NZ (1) NZ233065A (no)
PT (1) PT93535B (no)
ZA (1) ZA902307B (no)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
US4914102A (en) * 1989-09-28 1990-04-03 Hoechst Roussel Pharmaceuticals, Inc. N-aminocarbamates related to physostigmine, pharmacentical compositions and use
US5077289A (en) * 1989-11-30 1991-12-31 Hoechst Roussel Pharmaceuticals Inc. Memory enhancing and analgesic aminocarbonylcarbamates related to physostigmine
US4983616A (en) * 1990-02-01 1991-01-08 Hoechst-Roussel Pharmaceuticals Inc. Hexahydropyrrolo(2,3-B)indole carbamates, ureas, amides and related compounds
AU634654B2 (en) * 1990-05-11 1993-02-25 Hoechst-Roussel Pharmaceuticals Incorporated Pyrrolo(2,3-b)indole-ketones and analogs, a process for their preparation and their use as medicaments
US5216017A (en) * 1990-05-11 1993-06-01 Hoechst-Roussel Pharmaceuticals Incorporated Pyrrolo[2,3-b]indole-ketones and analogs
AU634380B2 (en) * 1990-05-17 1993-02-18 Hoechst-Roussel Pharmaceuticals Incorporated Alpha-oxopyrrolo(2,3-b)indole acetic acids, esters, amides and related analogs, a process for their preparation and their use as medicaments
DE4139763A1 (de) * 1991-12-03 1993-06-09 Kali-Chemie Pharma Gmbh, 3000 Hannover, De Kristalline fumarsaure salze von 9,9-alkylen-3,7-diazabicyclononan-verbindungen und diese verbindungen enthaltende arzneimittel
US5409948A (en) * 1992-11-23 1995-04-25 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Method for treating cognitive disorders with phenserine
AT404907B (de) * 1993-07-13 1999-03-25 Andritz Patentverwaltung Verfahren und anlage zum herstellen von edelstahlband
US5665880A (en) * 1996-10-31 1997-09-09 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseretholes
US5677457A (en) * 1996-12-19 1997-10-14 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseroline ethers
US20050182044A1 (en) * 2004-02-17 2005-08-18 Bruinsma Gosse B. Combinatorial therapy with an acetylcholinesterase inhibitor and (3aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydropyrrolo[2,3,-b]indol-5-yl phenylcarbamate
CA2508585A1 (en) * 2004-06-01 2005-12-01 Axonyx, Inc. Transdermal delivery system for treatment of cognitive disorders
EP1604686A1 (en) * 2004-06-08 2005-12-14 Axonyx, Inc. Use of phenserine and a HMG CoA reductase inhibitor for delaying Alzheimer's disease progression

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1109003B (it) * 1977-09-20 1985-12-16 Univ Firenze Derivati dell 1 2 3 8 3 a 8 a esai dropirrolo 23 b indolo
US4791107A (en) * 1986-07-16 1988-12-13 Hoechst-Roussel Pharmaceuticals, Inc. Memory enhancing and analgesic 1,2,3,3A,8,8A-hexahydro-3A,8 (and) 1,3A,8)-di(and tri)methylpyrrolo(2,3-B)indoles, compositions and use
US4914102A (en) * 1989-09-28 1990-04-03 Hoechst Roussel Pharmaceuticals, Inc. N-aminocarbamates related to physostigmine, pharmacentical compositions and use
US5077289A (en) * 1989-11-30 1991-12-31 Hoechst Roussel Pharmaceuticals Inc. Memory enhancing and analgesic aminocarbonylcarbamates related to physostigmine

Also Published As

Publication number Publication date
FI92932B (fi) 1994-10-14
FI92932C (fi) 1995-01-25
KR900014388A (ko) 1990-10-23
DE69020205D1 (de) 1995-07-27
EP0389984A1 (en) 1990-10-03
DE69020205T2 (de) 1995-12-07
AU621208B2 (en) 1992-03-05
AU5220290A (en) 1990-11-08
IL93895A0 (en) 1990-12-23
IE67449B1 (en) 1996-04-03
HU901832D0 (en) 1990-08-28
ES2075081T3 (es) 1995-10-01
KR0163049B1 (ko) 1998-12-01
JPH02289572A (ja) 1990-11-29
ZA902307B (en) 1990-12-28
JPH0737458B2 (ja) 1995-04-26
NZ233065A (en) 1992-04-28
CA2013087C (en) 1999-12-28
NO173995C (no) 1994-03-02
IL93895A (en) 1995-07-31
ATE124044T1 (de) 1995-07-15
NO901385L (no) 1990-09-28
US4971992A (en) 1990-11-20
NO173995B (no) 1993-11-22
HUT54159A (en) 1991-01-28
PT93535A (pt) 1990-11-07
EP0389984B1 (en) 1995-06-21
DK0389984T3 (da) 1995-10-30
FI901470A0 (fi) 1990-03-23
HU204053B (en) 1991-11-28
CA2013087A1 (en) 1990-09-27
IE901097L (en) 1990-09-27
PT93535B (pt) 1996-03-29

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NO901385L (no) Karbonatderivater av eserolin, fremgangsmaate for fremstilling derav og deres anvendelse som medikamenter.
DK0402752T3 (da) N-Heteroaryl-purin-6-aminer, fremgangsmåde til deres fremstilling og deres anvendelse som lægemidler
AU626740B2 (en) Aminocarbonylcarbamates related to physostigmine, a process for their preparation and their use as medicaments
ES2042727T3 (es) Acidos 1,3,4,9-tetrahidropirano(3,4-b)indol-1-acetico.