NO894944L - Dipeptid-derivater med enzym-hemmende virkning. - Google Patents

Dipeptid-derivater med enzym-hemmende virkning.

Info

Publication number
NO894944L
NO894944L NO89894944A NO894944A NO894944L NO 894944 L NO894944 L NO 894944L NO 89894944 A NO89894944 A NO 89894944A NO 894944 A NO894944 A NO 894944A NO 894944 L NO894944 L NO 894944L
Authority
NO
Norway
Prior art keywords
enzym
dipeptide derivatives
inhibitive effects
inhibitive
effects
Prior art date
Application number
NO89894944A
Other languages
English (en)
Norwegian (no)
Other versions
NO894944D0 (no
Inventor
Wolf-Ulrich Nickel
Hansjoerg Urbach
Dieter Ruppert
Bernward Schoelkens
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO894944D0 publication Critical patent/NO894944D0/no
Publication of NO894944L publication Critical patent/NO894944L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NO89894944A 1988-12-10 1989-12-08 Dipeptid-derivater med enzym-hemmende virkning. NO894944L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3841732A DE3841732A1 (de) 1988-12-10 1988-12-10 Dipeptid-derivate mit enzym-inhibitorischer wirkung

Publications (2)

Publication Number Publication Date
NO894944D0 NO894944D0 (no) 1989-12-08
NO894944L true NO894944L (no) 1990-06-11

Family

ID=6368937

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89894944A NO894944L (no) 1988-12-10 1989-12-08 Dipeptid-derivater med enzym-hemmende virkning.

Country Status (15)

Country Link
EP (1) EP0373497A3 (fi)
JP (1) JPH02202899A (fi)
KR (1) KR900009687A (fi)
CN (1) CN1043132A (fi)
AU (1) AU634188B2 (fi)
DD (1) DD290895A5 (fi)
DE (1) DE3841732A1 (fi)
DK (1) DK619989A (fi)
FI (1) FI895874A0 (fi)
HU (1) HU206371B (fi)
IL (1) IL92618A0 (fi)
NO (1) NO894944L (fi)
PT (1) PT92496A (fi)
RU (1) RU1836381C (fi)
ZA (1) ZA899407B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992003472A1 (en) * 1990-08-24 1992-03-05 The Upjohn Company Peptides containing amino-polyols as transition-state mimics
US6313094B1 (en) 1990-12-11 2001-11-06 Japan Energy Corporation β-amino-α-hydroxycarboxylic acid derivatives and HIV protease inhibitors
PL294870A1 (fi) * 1991-06-21 1993-02-08 Hoechst Ag
PL294866A1 (en) * 1991-06-21 1993-05-31 Hoechst Ag Method of obtaining novel rennin redtarding heterocyclic compounds
US6969731B1 (en) 1999-02-19 2005-11-29 The University of Illinois, Board of Trustees Protease inhibitors that overcome drug resistance
AU3369200A (en) * 1999-02-19 2000-09-04 Board Of Trustees Of The University Of Illinois, The Protease inhibitors that overcome drug resistance
DE10029077A1 (de) * 2000-06-13 2001-12-20 Bayer Ag Thiazolylsubstituierte Heterocyclen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3627877A1 (de) * 1986-07-30 1988-02-04 Hoechst Ag Renin-hemmende di- und tripeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
SE8605573D0 (sv) * 1986-12-29 1986-12-29 Haessle Ab Novel compounds

Also Published As

Publication number Publication date
DD290895A5 (de) 1991-06-13
DK619989D0 (da) 1989-12-08
AU4600389A (en) 1990-08-09
IL92618A0 (en) 1990-08-31
HU206371B (en) 1992-10-28
AU634188B2 (en) 1993-02-18
RU1836381C (ru) 1993-08-23
EP0373497A3 (de) 1991-04-10
PT92496A (pt) 1990-06-29
HUT54176A (en) 1991-01-28
CN1043132A (zh) 1990-06-20
FI895874A0 (fi) 1989-12-08
HU896475D0 (en) 1990-02-28
EP0373497A2 (de) 1990-06-20
KR900009687A (ko) 1990-07-05
JPH02202899A (ja) 1990-08-10
DK619989A (da) 1990-06-11
DE3841732A1 (de) 1990-06-13
NO894944D0 (no) 1989-12-08
ZA899407B (en) 1990-08-29

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