FI895874A0 - Dipeptidderivat med enzymreaktionshaemmande verkan. - Google Patents

Dipeptidderivat med enzymreaktionshaemmande verkan.

Info

Publication number
FI895874A0
FI895874A0 FI895874A FI895874A FI895874A0 FI 895874 A0 FI895874 A0 FI 895874A0 FI 895874 A FI895874 A FI 895874A FI 895874 A FI895874 A FI 895874A FI 895874 A0 FI895874 A0 FI 895874A0
Authority
FI
Finland
Prior art keywords
enzymreaktionshaemmande
dipeptidderivat
verkan
med
med enzymreaktionshaemmande
Prior art date
Application number
FI895874A
Other languages
English (en)
Inventor
Wolf-Ulrich Nickel
Hansjoerg Urbach
Dieter Ruppert
Bernward Schoelkens
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI895874A0 publication Critical patent/FI895874A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0227—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the (partial) peptide sequence -Phe-His-NH-(X)2-C(=0)-, e.g. Renin-inhibitors with n = 2 - 6; for n > 6 see C07K5/06 - C07K5/10
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/0606—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing heteroatoms not provided for by C07K5/06086 - C07K5/06139, e.g. Ser, Met, Cys, Thr
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI895874A 1988-12-10 1989-12-08 Dipeptidderivat med enzymreaktionshaemmande verkan. FI895874A0 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3841732A DE3841732A1 (de) 1988-12-10 1988-12-10 Dipeptid-derivate mit enzym-inhibitorischer wirkung

Publications (1)

Publication Number Publication Date
FI895874A0 true FI895874A0 (fi) 1989-12-08

Family

ID=6368937

Family Applications (1)

Application Number Title Priority Date Filing Date
FI895874A FI895874A0 (fi) 1988-12-10 1989-12-08 Dipeptidderivat med enzymreaktionshaemmande verkan.

Country Status (15)

Country Link
EP (1) EP0373497A3 (fi)
JP (1) JPH02202899A (fi)
KR (1) KR900009687A (fi)
CN (1) CN1043132A (fi)
AU (1) AU634188B2 (fi)
DD (1) DD290895A5 (fi)
DE (1) DE3841732A1 (fi)
DK (1) DK619989A (fi)
FI (1) FI895874A0 (fi)
HU (1) HU206371B (fi)
IL (1) IL92618A0 (fi)
NO (1) NO894944L (fi)
PT (1) PT92496A (fi)
RU (1) RU1836381C (fi)
ZA (1) ZA899407B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0546115A1 (en) * 1990-08-24 1993-06-16 The Upjohn Company Peptides containing amino-polyols as transition-state mimics
US6313094B1 (en) 1990-12-11 2001-11-06 Japan Energy Corporation β-amino-α-hydroxycarboxylic acid derivatives and HIV protease inhibitors
PL294866A1 (en) * 1991-06-21 1993-05-31 Hoechst Ag Method of obtaining novel rennin redtarding heterocyclic compounds
PL294870A1 (fi) * 1991-06-21 1993-02-08 Hoechst Ag
US6969731B1 (en) 1999-02-19 2005-11-29 The University of Illinois, Board of Trustees Protease inhibitors that overcome drug resistance
EP1155009A2 (en) * 1999-02-19 2001-11-21 Oklahoma Medical Research Foundation Protease inhibitors that overcome drug resistance
DE10029077A1 (de) * 2000-06-13 2001-12-20 Bayer Ag Thiazolylsubstituierte Heterocyclen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3627877A1 (de) * 1986-07-30 1988-02-04 Hoechst Ag Renin-hemmende di- und tripeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
SE8605573D0 (sv) * 1986-12-29 1986-12-29 Haessle Ab Novel compounds

Also Published As

Publication number Publication date
AU4600389A (en) 1990-08-09
CN1043132A (zh) 1990-06-20
DK619989A (da) 1990-06-11
EP0373497A3 (de) 1991-04-10
HU206371B (en) 1992-10-28
EP0373497A2 (de) 1990-06-20
RU1836381C (ru) 1993-08-23
KR900009687A (ko) 1990-07-05
HU896475D0 (en) 1990-02-28
DK619989D0 (da) 1989-12-08
JPH02202899A (ja) 1990-08-10
NO894944L (no) 1990-06-11
ZA899407B (en) 1990-08-29
IL92618A0 (en) 1990-08-31
PT92496A (pt) 1990-06-29
HUT54176A (en) 1991-01-28
NO894944D0 (no) 1989-12-08
AU634188B2 (en) 1993-02-18
DE3841732A1 (de) 1990-06-13
DD290895A5 (de) 1991-06-13

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Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: HOECHST AKTIENGESELLSCHAFT