NO894569L - Renin-inneholdende urinstoffderivater av dipeptider. - Google Patents

Renin-inneholdende urinstoffderivater av dipeptider.

Info

Publication number
NO894569L
NO894569L NO89894569A NO894569A NO894569L NO 894569 L NO894569 L NO 894569L NO 89894569 A NO89894569 A NO 89894569A NO 894569 A NO894569 A NO 894569A NO 894569 L NO894569 L NO 894569L
Authority
NO
Norway
Prior art keywords
dipeptid
purification containing
urinary
derivatives
urinary derivatives
Prior art date
Application number
NO89894569A
Other languages
English (en)
Norwegian (no)
Other versions
NO894569D0 (no
Inventor
Wolfgang Rueger
Hansjoerg Urbach
Dieter Ruppert
Bernward Schoelkens
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO894569D0 publication Critical patent/NO894569D0/no
Publication of NO894569L publication Critical patent/NO894569L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06139Dipeptides with the first amino acid being heterocyclic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO89894569A 1988-11-19 1989-11-16 Renin-inneholdende urinstoffderivater av dipeptider. NO894569L (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3839126A DE3839126A1 (de) 1988-11-19 1988-11-19 Renin-hemmende harnstoffderivate von dipeptiden, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung

Publications (2)

Publication Number Publication Date
NO894569D0 NO894569D0 (no) 1989-11-16
NO894569L true NO894569L (no) 1990-05-21

Family

ID=6367476

Family Applications (1)

Application Number Title Priority Date Filing Date
NO89894569A NO894569L (no) 1988-11-19 1989-11-16 Renin-inneholdende urinstoffderivater av dipeptider.

Country Status (12)

Country Link
EP (1) EP0370382A3 (da)
JP (1) JPH02180898A (da)
KR (1) KR900007868A (da)
AU (1) AU616071B2 (da)
DE (1) DE3839126A1 (da)
DK (1) DK579089A (da)
FI (1) FI895462A0 (da)
HU (1) HU203771B (da)
IL (1) IL92348A0 (da)
NO (1) NO894569L (da)
PT (1) PT92330A (da)
ZA (1) ZA898784B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3841520A1 (de) * 1988-12-09 1990-06-13 Hoechst Ag Enzymhemmende harnstoffderivate von dipeptiden, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
DE4014421A1 (de) * 1990-05-05 1991-11-07 Merck Patent Gmbh Aminosaeurederivate
DK2935222T3 (da) 2012-12-21 2019-01-07 Epizyme Inc Prmt5-inhibitorer og anvendelser deraf
CA2899363A1 (en) 2012-12-21 2014-06-26 Epizyme, Inc. Prmt5 inhibitors and uses thereof
JP2016505000A (ja) 2012-12-21 2016-02-18 エピザイム,インコーポレイティド Prmt5阻害剤およびその使用
WO2014100734A1 (en) 2012-12-21 2014-06-26 Epizyme, Inc. Prmt5 inhibitors and uses thereof
US9745291B2 (en) 2012-12-21 2017-08-29 Epizyme, Inc. PRMT5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof
EP3177288A4 (en) 2014-08-04 2018-04-04 Epizyme, Inc. Prmt5 inhibitors and uses thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA87563B (en) * 1986-02-03 1987-09-30 Squibb & Sons Inc N-heterocyclic alcohol renin inhibitors
DE3627877A1 (de) * 1986-07-30 1988-02-04 Hoechst Ag Renin-hemmende di- und tripeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung
GB8707412D0 (en) * 1987-03-27 1987-04-29 Fujisawa Pharmaceutical Co Peptide compounds
DE3841520A1 (de) * 1988-12-09 1990-06-13 Hoechst Ag Enzymhemmende harnstoffderivate von dipeptiden, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung

Also Published As

Publication number Publication date
FI895462A0 (fi) 1989-11-16
HU203771B (en) 1991-09-30
DK579089D0 (da) 1989-11-17
EP0370382A2 (de) 1990-05-30
KR900007868A (ko) 1990-06-02
PT92330A (pt) 1990-05-31
EP0370382A3 (de) 1991-04-10
NO894569D0 (no) 1989-11-16
AU616071B2 (en) 1991-10-17
AU4479889A (en) 1990-08-09
DE3839126A1 (de) 1990-05-23
IL92348A0 (en) 1990-07-26
HU895948D0 (en) 1990-02-28
DK579089A (da) 1990-05-20
JPH02180898A (ja) 1990-07-13
ZA898784B (en) 1990-08-29
HUT53122A (en) 1990-09-28

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