AU4479889A - Renin-inhibiting urea derivatives of dipeptides, a process for the preparation thereof, agents containing these, and the use thereof - Google Patents
Renin-inhibiting urea derivatives of dipeptides, a process for the preparation thereof, agents containing these, and the use thereofInfo
- Publication number
- AU4479889A AU4479889A AU44798/89A AU4479889A AU4479889A AU 4479889 A AU4479889 A AU 4479889A AU 44798/89 A AU44798/89 A AU 44798/89A AU 4479889 A AU4479889 A AU 4479889A AU 4479889 A AU4479889 A AU 4479889A
- Authority
- AU
- Australia
- Prior art keywords
- dipeptides
- renin
- preparation
- urea derivatives
- agents containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
- C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE3839126 | 1988-11-19 | ||
DE3839126A DE3839126A1 (en) | 1988-11-19 | 1988-11-19 | RENIN-INHIBITING UREA DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THEIR USE |
Publications (2)
Publication Number | Publication Date |
---|---|
AU4479889A true AU4479889A (en) | 1990-08-09 |
AU616071B2 AU616071B2 (en) | 1991-10-17 |
Family
ID=6367476
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU44798/89A Expired - Fee Related AU616071B2 (en) | 1988-11-19 | 1989-11-17 | Renin-inhibiting urea derivatives of dipeptides, a process for the preparation thereof, agents containing these, and the use thereof |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0370382A3 (en) |
JP (1) | JPH02180898A (en) |
KR (1) | KR900007868A (en) |
AU (1) | AU616071B2 (en) |
DE (1) | DE3839126A1 (en) |
DK (1) | DK579089A (en) |
FI (1) | FI895462A0 (en) |
HU (1) | HU203771B (en) |
IL (1) | IL92348A0 (en) |
NO (1) | NO894569L (en) |
PT (1) | PT92330A (en) |
ZA (1) | ZA898784B (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU630386B2 (en) * | 1988-12-09 | 1992-10-29 | Hoechst Aktiengesellschaft | Enzyme-inhibiting urea derivatives of dipeptides, a process for the preparation thereof, agents containing these, and the use thereof |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4014421A1 (en) * | 1990-05-05 | 1991-11-07 | Merck Patent Gmbh | AMINOSAEUREDERIVATE |
WO2014100730A1 (en) | 2012-12-21 | 2014-06-26 | Epizyme, Inc. | Prmt5 inhibitors containing a dihydro- or tetrahydroisoquinoline and uses thereof |
JP2016505597A (en) | 2012-12-21 | 2016-02-25 | エピザイム,インコーポレイティド | PRMT5 inhibitors and uses thereof |
US9365555B2 (en) | 2012-12-21 | 2016-06-14 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
US9908887B2 (en) | 2012-12-21 | 2018-03-06 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
US8993555B2 (en) | 2012-12-21 | 2015-03-31 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
US10653693B2 (en) | 2014-08-04 | 2020-05-19 | Epizyme, Inc. | PRMT5 inhibitors and uses thereof |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ZA87563B (en) * | 1986-02-03 | 1987-09-30 | Squibb & Sons Inc | N-heterocyclic alcohol renin inhibitors |
DE3627877A1 (en) * | 1986-07-30 | 1988-02-04 | Hoechst Ag | RENINE-INHIBITING DI- AND TRIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THEIR USE |
GB8707412D0 (en) * | 1987-03-27 | 1987-04-29 | Fujisawa Pharmaceutical Co | Peptide compounds |
DE3841520A1 (en) * | 1988-12-09 | 1990-06-13 | Hoechst Ag | ENZYME-INFRINGING DERIVATIVES OF DIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, METHODS CONTAINING THEM AND THEIR USE |
-
1988
- 1988-11-19 DE DE3839126A patent/DE3839126A1/en not_active Withdrawn
-
1989
- 1989-11-16 NO NO89894569A patent/NO894569L/en unknown
- 1989-11-16 FI FI895462A patent/FI895462A0/en not_active Application Discontinuation
- 1989-11-16 EP EP19890121189 patent/EP0370382A3/en not_active Withdrawn
- 1989-11-16 PT PT92330A patent/PT92330A/en not_active Application Discontinuation
- 1989-11-17 HU HU895948A patent/HU203771B/en not_active IP Right Cessation
- 1989-11-17 IL IL92348A patent/IL92348A0/en unknown
- 1989-11-17 JP JP1297790A patent/JPH02180898A/en active Pending
- 1989-11-17 ZA ZA898784A patent/ZA898784B/en unknown
- 1989-11-17 KR KR1019890016676A patent/KR900007868A/en not_active Application Discontinuation
- 1989-11-17 AU AU44798/89A patent/AU616071B2/en not_active Expired - Fee Related
- 1989-11-17 DK DK579089A patent/DK579089A/en not_active Application Discontinuation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU630386B2 (en) * | 1988-12-09 | 1992-10-29 | Hoechst Aktiengesellschaft | Enzyme-inhibiting urea derivatives of dipeptides, a process for the preparation thereof, agents containing these, and the use thereof |
Also Published As
Publication number | Publication date |
---|---|
HU895948D0 (en) | 1990-02-28 |
NO894569L (en) | 1990-05-21 |
HU203771B (en) | 1991-09-30 |
JPH02180898A (en) | 1990-07-13 |
DE3839126A1 (en) | 1990-05-23 |
NO894569D0 (en) | 1989-11-16 |
DK579089A (en) | 1990-05-20 |
ZA898784B (en) | 1990-08-29 |
DK579089D0 (en) | 1989-11-17 |
FI895462A0 (en) | 1989-11-16 |
HUT53122A (en) | 1990-09-28 |
EP0370382A2 (en) | 1990-05-30 |
PT92330A (en) | 1990-05-31 |
EP0370382A3 (en) | 1991-04-10 |
AU616071B2 (en) | 1991-10-17 |
IL92348A0 (en) | 1990-07-26 |
KR900007868A (en) | 1990-06-02 |
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