NO892021L - Fremgangsmaate for fremstilling av pyrrolidinderivater. - Google Patents

Fremgangsmaate for fremstilling av pyrrolidinderivater.

Info

Publication number
NO892021L
NO892021L NO89892021A NO892021A NO892021L NO 892021 L NO892021 L NO 892021L NO 89892021 A NO89892021 A NO 89892021A NO 892021 A NO892021 A NO 892021A NO 892021 L NO892021 L NO 892021L
Authority
NO
Norway
Prior art keywords
pyrrolide
ingredients
preparing
procedure
pyrrolide ingredients
Prior art date
Application number
NO89892021A
Other languages
English (en)
Other versions
NO174463C (no
NO174463B (no
NO892021D0 (no
Inventor
Angelo Carenzi
Dario Chiarino
Davide Della Bella
Gian Carlo Grancini
Carlo Veneziani
Original Assignee
Zambon Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT20648/88A external-priority patent/IT1217657B/it
Priority claimed from IT8919480A external-priority patent/IT1230754B/it
Application filed by Zambon Spa filed Critical Zambon Spa
Publication of NO892021D0 publication Critical patent/NO892021D0/no
Publication of NO892021L publication Critical patent/NO892021L/no
Publication of NO174463B publication Critical patent/NO174463B/no
Publication of NO174463C publication Critical patent/NO174463C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
NO892021A 1988-05-20 1989-05-19 Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrrolidinderivater NO174463C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT20648/88A IT1217657B (it) 1988-05-20 1988-05-20 Composti con attivita' analgesica centrale
IT8919480A IT1230754B (it) 1989-02-17 1989-02-17 Camposti con attivita' analgesica centrale.

Publications (4)

Publication Number Publication Date
NO892021D0 NO892021D0 (no) 1989-05-19
NO892021L true NO892021L (no) 1989-11-21
NO174463B NO174463B (no) 1994-01-31
NO174463C NO174463C (no) 1994-05-11

Family

ID=26327181

Family Applications (1)

Application Number Title Priority Date Filing Date
NO892021A NO174463C (no) 1988-05-20 1989-05-19 Analogifremgangsmåte for fremstilling av terapeutisk aktive pyrrolidinderivater

Country Status (15)

Country Link
US (1) US4960788A (no)
EP (1) EP0342613B1 (no)
JP (1) JP2802437B2 (no)
AU (1) AU624382B2 (no)
CA (1) CA1336333C (no)
DE (1) DE68903425T2 (no)
DK (1) DK172008B1 (no)
ES (1) ES2043943T3 (no)
FI (1) FI90662C (no)
GR (1) GR3006803T3 (no)
HU (1) HU208420B (no)
IE (1) IE61631B1 (no)
IL (1) IL90324A0 (no)
NO (1) NO174463C (no)
SU (1) SU1727531A3 (no)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2653123B1 (fr) * 1989-10-17 1992-01-17 Roussel Uclaf Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant.
IT1239950B (it) * 1990-03-28 1993-11-27 Zambon Spa Processo per la preparazione di composti con attivita' analgesica centrale
US5208345A (en) * 1990-12-17 1993-05-04 Merrell Dow Pharmaceuticals Inc. Process for the production of (S)-vinyl and allenyl gaba
AU644919B2 (en) * 1990-12-17 1993-12-23 Aventisub Ii Inc. Process for the production of (S)-vinyl and allenyl gaba
US7105537B2 (en) 2003-01-28 2006-09-12 Bristol-Myers Squibb Company 2-substituted cyclic amines as calcium sensing receptor modulators
US7205322B2 (en) 2003-02-12 2007-04-17 Bristol-Myers Squibb Company Thiazolidine compounds as calcium sensing receptor modulators
US7265145B2 (en) 2003-05-28 2007-09-04 Bristol-Myers Squibb Company Substituted piperidines and pyrrolidines as calcium sensing receptor modulators and method
CA2632453A1 (en) * 2005-12-07 2007-06-14 Ucb Pharma, S.A. 3-carboxy- 2-oxo-1 -pyrrolidine derivatives and their uses
CN115475162B (zh) * 2022-10-18 2023-06-02 浙江震元制药有限公司 4-异丁基-2-吡咯烷酮在制备镇痛药物中的应用、一种镇痛药物

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2496163A (en) * 1948-03-30 1950-01-31 Du Pont Synthesis of a 2-substituted-5-oxopyrrolidine
BE790747A (fr) * 1971-10-30 1973-02-15 Whitefin Holding Sa Stereo-isomeres du 1-(1'-(0-chloro-benzyl)-pyrrol-2'-yl) -2-dibutyl sec.-amino-ethanol et procede pour leur preparation
IE45511B1 (en) * 1976-09-01 1982-09-08 Ciba Geigy Ag New derivatives of perhydro-aza-heterocycles and processesfor the production thereof
US4525476A (en) * 1983-05-26 1985-06-25 Warner-Lambert Company N-[1-oxo-3-(5-oxo-2-pyrrolidinyl)propyl]-alpha-aminoacids and derivatives as cognition activators
FR2549053B1 (fr) * 1983-07-12 1985-12-27 Sanofi Sa Nouveaux derives de la pyrrolidine actifs sur le systeme nerveux central, leur procede de preparation, les medicaments en contenant
DE3336024A1 (de) * 1983-10-04 1985-04-18 Boehringer Ingelheim KG, 6507 Ingelheim 4-amino-l-benzyl-pyrrolidinone und ihre saeureadditionssalze, verfahren zu ihrer herstellung und arzneimittel
DE3420193A1 (de) * 1984-05-30 1985-12-05 Boehringer Ingelheim KG, 6507 Ingelheim Neue substituierte pyrrolidinone, verfahren zu ihrer herstellung und arzneimittel

Also Published As

Publication number Publication date
IE891578L (en) 1989-11-20
DE68903425T2 (de) 1993-03-25
HU208420B (en) 1993-10-28
JP2802437B2 (ja) 1998-09-24
FI90662B (fi) 1993-11-30
AU624382B2 (en) 1992-06-11
CA1336333C (en) 1995-07-18
FI892420A0 (fi) 1989-05-19
NO174463C (no) 1994-05-11
GR3006803T3 (no) 1993-06-30
DK172008B1 (da) 1997-09-15
HUT50765A (en) 1990-03-28
DK244389A (da) 1989-12-20
NO174463B (no) 1994-01-31
EP0342613A1 (en) 1989-11-23
SU1727531A3 (ru) 1992-04-15
IL90324A0 (en) 1989-12-15
AU3499389A (en) 1989-11-23
DE68903425D1 (de) 1992-12-17
NO892021D0 (no) 1989-05-19
FI90662C (fi) 1994-03-10
DK244389D0 (da) 1989-05-19
JPH0217176A (ja) 1990-01-22
US4960788A (en) 1990-10-02
IE61631B1 (en) 1994-11-16
EP0342613B1 (en) 1992-11-11
ES2043943T3 (es) 1994-01-01
FI892420A (fi) 1989-11-21

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