NO891381L - Fremgangsmaate for fremstilling av nye fluorfosfonatnukleotidderivater. - Google Patents
Fremgangsmaate for fremstilling av nye fluorfosfonatnukleotidderivater.Info
- Publication number
- NO891381L NO891381L NO89891381A NO891381A NO891381L NO 891381 L NO891381 L NO 891381L NO 89891381 A NO89891381 A NO 89891381A NO 891381 A NO891381 A NO 891381A NO 891381 L NO891381 L NO 891381L
- Authority
- NO
- Norway
- Prior art keywords
- preparation
- new
- fluorphosphonate
- procedure
- nucleotide derivatives
- Prior art date
Links
- 239000002773 nucleotide Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000002015 acyclic group Chemical group 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
- C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6503—Five-membered rings
- C07F9/6506—Five-membered rings having the nitrogen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
- C07F9/6518—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
- C07F9/6521—Six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
- C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP88400806A EP0339161A1 (fr) | 1988-04-01 | 1988-04-01 | Dérivés de nucléotides de fluorophosphonates |
| EP89400773A EP0335770B1 (fr) | 1988-04-01 | 1989-03-20 | Dérivés de nucléotides de fluorophosphonates |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO891381D0 NO891381D0 (no) | 1989-03-31 |
| NO891381L true NO891381L (no) | 1989-10-02 |
Family
ID=26117598
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO89891381A NO891381L (no) | 1988-04-01 | 1989-03-31 | Fremgangsmaate for fremstilling av nye fluorfosfonatnukleotidderivater. |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0335770B1 (fr) |
| JP (1) | JPH0272192A (fr) |
| CN (1) | CN1036578A (fr) |
| AU (2) | AU614128B2 (fr) |
| DK (1) | DK157389A (fr) |
| FI (1) | FI891462A (fr) |
| HU (1) | HU204535B (fr) |
| IL (1) | IL89771A0 (fr) |
| NO (1) | NO891381L (fr) |
| NZ (1) | NZ228492A (fr) |
| PT (1) | PT90179B (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2085446T3 (es) * | 1990-07-04 | 1996-06-01 | Merrell Pharma Inc | Derivados de acido 9-purinil fosfonico. |
| US5349018A (en) * | 1991-01-17 | 1994-09-20 | Tomoegawa Paper Co., Ltd. | Polyamide-hydrogenated polybutadiene-acrylonitrile copolymers |
| US5798340A (en) | 1993-09-17 | 1998-08-25 | Gilead Sciences, Inc. | Nucleotide analogs |
| JPH09506333A (ja) * | 1993-09-17 | 1997-06-24 | ギリアード サイエンシーズ，インコーポレイテッド | 治療化合物の投薬方法 |
| JP5049067B2 (ja) * | 2007-07-31 | 2012-10-17 | 東ソ−・エフテック株式会社 | 含フッ素非環状ｎ，ｏ−アセタール化合物の製造方法 |
| CN102079760A (zh) * | 2010-12-24 | 2011-06-01 | 南京师范大学 | α-二氟亚甲基膦内酯的合成方法 |
| EP3292912B1 (fr) * | 2016-09-09 | 2019-12-25 | Loesche GmbH | Procédé de fonctionnement d'un multicyclone pour la séparation de grains fins et ultrafins ainsi que multicyclones |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU729196A1 (ru) * | 1976-11-26 | 1980-04-25 | Московский Ордена Ленина И Ордена Трудового Красного Знамени Государственный Университет Им.М.В.Ломоносова | Способ получени фосфонатных эфиров нуклеозидов |
| US4266282A (en) * | 1979-03-12 | 1981-05-05 | International Business Machines Corporation | Vertical semiconductor integrated circuit chip packaging |
| US4452790A (en) * | 1982-06-23 | 1984-06-05 | E. R. Squibb & Sons, Inc. | Phosphonyl hydroxyacyl amino acid derivatives as antihypertensives |
| CS263951B1 (en) * | 1985-04-25 | 1989-05-12 | Antonin Holy | 9-(phosponylmethoxyalkyl)adenines and method of their preparation |
| EP0309491A1 (fr) * | 1987-01-20 | 1989-04-05 | Sri International | Agents antiviraux |
| GB8921469D0 (en) * | 1989-09-22 | 1989-11-08 | Erba Carlo Spa | 5'-alkylphosphonylnucleosides as antivirals |
-
1989
- 1989-03-20 EP EP89400773A patent/EP0335770B1/fr not_active Expired - Lifetime
- 1989-03-28 FI FI891462A patent/FI891462A/fi not_active Application Discontinuation
- 1989-03-28 IL IL89771A patent/IL89771A0/xx unknown
- 1989-03-29 NZ NZ228492A patent/NZ228492A/en unknown
- 1989-03-31 JP JP1078743A patent/JPH0272192A/ja active Pending
- 1989-03-31 NO NO89891381A patent/NO891381L/no unknown
- 1989-03-31 PT PT90179A patent/PT90179B/pt not_active IP Right Cessation
- 1989-03-31 HU HU891608A patent/HU204535B/hu not_active IP Right Cessation
- 1989-03-31 DK DK157389A patent/DK157389A/da not_active IP Right Cessation
- 1989-04-01 CN CN89101905A patent/CN1036578A/zh active Pending
- 1989-04-03 AU AU32410/89A patent/AU614128B2/en not_active Ceased
-
1991
- 1991-06-14 AU AU78366/91A patent/AU631319B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| DK157389D0 (da) | 1989-03-31 |
| EP0335770A3 (fr) | 1990-12-27 |
| IL89771A0 (en) | 1989-09-28 |
| EP0335770A2 (fr) | 1989-10-04 |
| NO891381D0 (no) | 1989-03-31 |
| AU614128B2 (en) | 1991-08-22 |
| HU204535B (en) | 1992-01-28 |
| AU7836691A (en) | 1991-09-12 |
| FI891462A (fi) | 1989-10-02 |
| PT90179A (pt) | 1989-11-10 |
| HUT49627A (en) | 1989-10-30 |
| PT90179B (pt) | 1994-06-30 |
| EP0335770B1 (fr) | 1997-01-15 |
| NZ228492A (en) | 1991-07-26 |
| AU631319B2 (en) | 1992-11-19 |
| FI891462A0 (fi) | 1989-03-28 |
| CN1036578A (zh) | 1989-10-25 |
| DK157389A (da) | 1989-10-02 |
| AU3241089A (en) | 1989-10-05 |
| JPH0272192A (ja) | 1990-03-12 |
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