NO882986D0 - Fremgangsmaate for fremstilling av organiske fosforforbindelser. - Google Patents

Fremgangsmaate for fremstilling av organiske fosforforbindelser.

Info

Publication number
NO882986D0
NO882986D0 NO882986A NO882986A NO882986D0 NO 882986 D0 NO882986 D0 NO 882986D0 NO 882986 A NO882986 A NO 882986A NO 882986 A NO882986 A NO 882986A NO 882986 D0 NO882986 D0 NO 882986D0
Authority
NO
Norway
Prior art keywords
phosphores
procedure
organic
preparation
ester
Prior art date
Application number
NO882986A
Other languages
English (en)
Other versions
NO176479B (no
NO176479C (no
NO882986L (no
Inventor
Frank Hallock Ebetino
Original Assignee
Norwich Eaton Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norwich Eaton Pharma filed Critical Norwich Eaton Pharma
Publication of NO882986D0 publication Critical patent/NO882986D0/no
Publication of NO882986L publication Critical patent/NO882986L/no
Publication of NO176479B publication Critical patent/NO176479B/no
Publication of NO176479C publication Critical patent/NO176479C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/28Phosphorus compounds with one or more P—C bonds
    • C07F9/38Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3808Acyclic saturated acids which can have further substituents on alkyl
    • C07F9/3821Acyclic saturated acids which can have further substituents on alkyl substituted by B, Si, P or a metal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/59Hydrogenated pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Luminescent Compositions (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
NO882986A 1987-07-06 1988-07-05 Fremgangsmåte for fremstilling av aminometylenfosfonalkylfosfinatforbindelser NO176479C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/069,663 US4963681A (en) 1987-07-06 1987-07-06 Process for synthesis of aminomethylene phosphonoalkylphosphinates

Publications (4)

Publication Number Publication Date
NO882986D0 true NO882986D0 (no) 1988-07-05
NO882986L NO882986L (no) 1989-01-09
NO176479B NO176479B (no) 1995-01-02
NO176479C NO176479C (no) 1995-04-12

Family

ID=22090440

Family Applications (1)

Application Number Title Priority Date Filing Date
NO882986A NO176479C (no) 1987-07-06 1988-07-05 Fremgangsmåte for fremstilling av aminometylenfosfonalkylfosfinatforbindelser

Country Status (23)

Country Link
US (1) US4963681A (no)
EP (1) EP0298555B1 (no)
JP (1) JPS6485985A (no)
KR (1) KR960008094B1 (no)
AT (1) ATE67500T1 (no)
AU (1) AU607781B2 (no)
CA (1) CA1322077C (no)
DE (1) DE3864927D1 (no)
DK (1) DK375688A (no)
EG (1) EG18559A (no)
ES (1) ES2029875T3 (no)
FI (1) FI88721C (no)
GR (1) GR3002741T3 (no)
HK (1) HK54294A (no)
IE (1) IE60912B1 (no)
IL (1) IL86952A (no)
MX (1) MX171302B (no)
MY (1) MY106953A (no)
NO (1) NO176479C (no)
NZ (1) NZ225273A (no)
PH (1) PH25817A (no)
PT (1) PT87916B (no)
ZA (1) ZA884793B (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8825589D0 (en) * 1988-11-02 1988-12-07 Albright & Wilson Purification
US5562894A (en) * 1991-08-09 1996-10-08 Regents Of The University Of California Amino-acyl-type and catecholamine-type contrast agents for MRI
ATE147396T1 (de) * 1991-08-27 1997-01-15 Ciba Geigy Ag N-substituierte aminomethandiphosphonsäuren
US5278153A (en) * 1992-05-18 1994-01-11 E. R. Squibb & Sons, Inc. Aryl and heteroaryl (phosphinylmethyl)phosphonate squalene synthetase inhibitors and method
CN101784366A (zh) 2007-11-27 2010-07-21 播磨化成株式会社 钎焊用焊剂及钎焊膏组合物
WO2009069601A1 (ja) 2007-11-27 2009-06-04 Harima Chemicals, Inc. はんだ付け用フラックス、はんだペースト組成物およびはんだ付け方法
GB201200868D0 (en) 2012-01-19 2012-02-29 Depuy Int Ltd Bone filler composition

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3553314A (en) * 1968-12-23 1971-01-05 Procter & Gamble Oral compositions for calculus retardation
US3979385A (en) * 1969-11-19 1976-09-07 Henkel & Cie G.M.B.H. 1-Aminoalkane-1,1-diphosphonic acids and their salts
DE1958123C3 (de) * 1969-11-19 1978-09-28 Henkel Kgaa, 4000 Duesseldorf Verfahren zur Herstellung von 1 -Aminoalkan-1,1 -diphosphonsäuren oder deren Salzen
US3683080A (en) * 1970-08-28 1972-08-08 Procter & Gamble Compositions for inhibiting anomalous deposition and mobilization of calcium phosphate in animal tissue
US3899496A (en) * 1970-10-06 1975-08-12 Henkel & Cie Gmbh Production of 1-aminoalkane-1,1-diphosphonic acids
DE2104476C2 (de) * 1971-02-01 1983-12-01 Henkel KGaA, 4000 Düsseldorf Verfahren zur Verhinderung von Ausfällungen in Wasser oder wäßrigen Lösungen
US3988443A (en) * 1973-08-27 1976-10-26 Henkel & Cie G.M.B.H. Azacycloalkane-2,2-diphosphonic acids
DE2343196C3 (de) * 1973-08-27 1980-01-10 Henkel Kgaa, 4000 Duesseldorf Aiacycloalkan-2^-diphosphonsäuren oder deren wasserlösliche Salze
DE2360798A1 (de) * 1973-12-06 1975-06-26 Henkel & Cie Gmbh Pharmazeutische oder kosmetische praeparate
US4134969A (en) * 1974-02-04 1979-01-16 Henkel Kommanditgesellschaft Auf Aktien (Henkel Kgaa) Method of treatment of calcium disorders using aminoalkane-diphosphonic acids
DE2456666A1 (de) * 1974-11-30 1976-08-12 Henkel & Cie Gmbh Verfahren zum stabilisieren von calcium-hydrogenphosphat-dihydrat gegen hydrolyse
US4113861A (en) * 1977-05-02 1978-09-12 The Procter & Gamble Company Phosphonate pharmaceutical composition
DE2745083C2 (de) * 1977-10-07 1985-05-02 Henkel KGaA, 4000 Düsseldorf Hydroxydiphosphonsäuren und Verfahren zu deren Herstellung
IL61985A0 (en) * 1980-02-01 1981-02-27 Sparamedica Ag Phosphinic and phosphonic acid derivatives,their manufacture and pharmaceutical compositions containing them
DE3016289A1 (de) * 1980-04-28 1981-10-29 Henkel KGaA, 4000 Düsseldorf Verfahren zur herstellung von omega -amino-1-hydroxyalkyliden-1,1-bis-phosphonsaeuren
US4304734A (en) * 1980-10-16 1981-12-08 Vysoka Skola Chemicko-Technologicka 6-Amino-1-hydroxyhexylidene diphosphonic acid, salts and a process for production thereof
IT1201087B (it) * 1982-04-15 1989-01-27 Gentili Ist Spa Bifosfonati farmacologicamente attivi,procedimento per la loro preparazione e relative composizioni farmaceutiche
DE3425812A1 (de) * 1984-07-13 1986-01-16 Deutsches Krebsforschungszentrum, 6900 Heidelberg Neue 1-hydroxy-1,1-diphosphonsaeureverbindungen, verfahren zu ihrer herstellung und pharmakologische zubereitungen, insbesondere zur behandlung von knochentumoren
DE3428524A1 (de) * 1984-08-02 1986-02-13 Boehringer Mannheim Gmbh, 6800 Mannheim Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US4639338A (en) * 1984-08-06 1987-01-27 Ciba-Geigy Corporation Preparation of crystalline disodium 3-amino-1-hydroxypropane-1,1-diphosphonate pentahydrate
US4687768A (en) * 1984-12-21 1987-08-18 The Procter & Gamble Company Certain hexahydroindan-2,2-diphosphonic acids useful in treating diseases associated with abnormal calcium and phosphate metabolism
DE3540150A1 (de) * 1985-11-13 1987-05-14 Boehringer Mannheim Gmbh Neue diphosphonsaeurederivate, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
US4902679A (en) * 1985-12-13 1990-02-20 Norwich Eaton Pharmaceuticals, Inc. Methods of treating diseases with certain geminal diphosphonates
IL86951A (en) * 1987-07-06 1996-07-23 Procter & Gamble Pharma Methylene phosphonoalkylphosphinates and pharmaceutical preparations containing them
US4871721A (en) * 1988-01-11 1989-10-03 E. R. Squibb & Sons, Inc. Phosphorus-containing squalene synthetase inhibitors

Also Published As

Publication number Publication date
IL86952A (en) 1993-01-14
IE882051L (en) 1989-01-06
FI88721B (fi) 1993-03-15
DE3864927D1 (de) 1991-10-24
DK375688D0 (da) 1988-07-06
PT87916B (pt) 1995-03-01
CA1322077C (en) 1993-09-07
JPS6485985A (en) 1989-03-30
ES2029875T3 (es) 1992-10-01
IL86952A0 (en) 1988-12-30
NO176479B (no) 1995-01-02
FI883207A (fi) 1989-01-07
AU607781B2 (en) 1991-03-14
KR960008094B1 (ko) 1996-06-19
ATE67500T1 (de) 1991-10-15
EG18559A (en) 1993-06-30
DK375688A (da) 1989-01-07
NO176479C (no) 1995-04-12
US4963681A (en) 1990-10-16
EP0298555A1 (en) 1989-01-11
AU1876688A (en) 1989-01-12
PT87916A (pt) 1989-06-30
KR890002208A (ko) 1989-04-10
MY106953A (en) 1995-08-30
GR3002741T3 (en) 1993-01-25
NO882986L (no) 1989-01-09
FI88721C (fi) 1993-06-28
NZ225273A (en) 1991-07-26
ZA884793B (en) 1989-03-29
EP0298555B1 (en) 1991-09-18
PH25817A (en) 1991-11-05
FI883207A0 (fi) 1988-07-05
MX171302B (es) 1993-10-18
HK54294A (en) 1994-06-03
IE60912B1 (en) 1994-08-24

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Legal Events

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MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN JANUARY 2002