NO861820L - Fremgangsmaate for fremstilling av 2-pyrrolidon-derivater. - Google Patents
Fremgangsmaate for fremstilling av 2-pyrrolidon-derivater.Info
- Publication number
- NO861820L NO861820L NO861820A NO861820A NO861820L NO 861820 L NO861820 L NO 861820L NO 861820 A NO861820 A NO 861820A NO 861820 A NO861820 A NO 861820A NO 861820 L NO861820 L NO 861820L
- Authority
- NO
- Norway
- Prior art keywords
- pyrrolidon
- derivatives
- preparing
- procedure
- alkylene
- Prior art date
Links
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical class O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 title 1
- HTYBLOZYHRDDCZ-UHFFFAOYSA-N 3-[(3,5-ditert-butyl-4-hydroxyphenyl)methylidene]pyrrolidin-2-one Chemical compound CC(C)(C)C1=C(O)C(C(C)(C)C)=CC(C=C2C(NCC2)=O)=C1 HTYBLOZYHRDDCZ-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000006294 amino alkylene group Chemical group 0.000 abstract 1
- 230000001760 anti-analgesic effect Effects 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 150000003953 γ-lactams Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
- C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/46—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with hetero atoms directly attached to the ring nitrogen atom
- C07D207/50—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Rheumatology (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP60096799A JPH066571B2 (ja) | 1985-05-09 | 1985-05-09 | ２−ピロリドン誘導体 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO861820L true NO861820L (no) | 1986-11-10 |
Family
ID=14174668
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO861820A NO861820L (no) | 1985-05-09 | 1986-05-07 | Fremgangsmaate for fremstilling av 2-pyrrolidon-derivater. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4833160A (es) |
| EP (1) | EP0204964B1 (es) |
| JP (1) | JPH066571B2 (es) |
| KR (1) | KR910004789B1 (es) |
| CN (1) | CN1014058B (es) |
| AT (1) | ATE66673T1 (es) |
| AU (1) | AU581078B2 (es) |
| CA (1) | CA1264762A (es) |
| DE (1) | DE3681076D1 (es) |
| DK (1) | DK213286A (es) |
| ES (1) | ES8800148A1 (es) |
| FI (1) | FI84172C (es) |
| HU (2) | HU199117B (es) |
| MX (1) | MX162717A (es) |
| NO (1) | NO861820L (es) |
| NZ (1) | NZ216092A (es) |
| PH (2) | PH23189A (es) |
| PT (1) | PT82540B (es) |
| ZA (1) | ZA863352B (es) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5691367A (en) * | 1985-08-09 | 1997-11-25 | Eli Lilly And Company | Aryl-substituted rhodanine derivatives |
| US5356917A (en) * | 1985-08-09 | 1994-10-18 | Eli Lilly And Company | Aryl-substituted rhodanine derivatives |
| US5089516A (en) * | 1987-03-11 | 1992-02-18 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | 1-phenyl-3,5-pyrazolidinedione hydroxystyrene compounds which have tyrosine kinase inhibiting activity |
| US5202341A (en) * | 1987-03-11 | 1993-04-13 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Hydroxystyrene compounds having tyrosine kinase inhibiting activity |
| WO1988007035A1 (en) * | 1987-03-11 | 1988-09-22 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Hydroxystyrene derivatives |
| US5216002A (en) * | 1989-12-21 | 1993-06-01 | Eli Lilly And Company | Method of treating inflammatory bowel disease |
| US5143928A (en) * | 1990-03-27 | 1992-09-01 | Warner-Lambert Company | 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents |
| JP3108097B2 (ja) * | 1991-01-21 | 2000-11-13 | 塩野義製薬株式会社 | ３−ベンジリデン−１−カルバモイル−２−ピロリドン類縁体 |
| WO1992017447A1 (en) * | 1991-04-05 | 1992-10-15 | Kanegafuchi Kagaku Kogyo Kabushiki Kaisha | Phenoxybenzene derivative |
| EP0595546B1 (en) * | 1992-10-28 | 1996-03-20 | Shionogi & Co., Ltd. | Benzylidene derivatives |
| US5358964A (en) * | 1993-07-26 | 1994-10-25 | Warner-Lambert Company | Benzylidene-lactone and their thiocarbonyl analogs as inhibitors of proteoglycan degradation |
| GB9704499D0 (en) | 1997-03-05 | 1997-04-23 | Glaxo Wellcome Spa | Method of manufacture |
| CN103342672B (zh) * | 2013-07-02 | 2015-12-23 | 扬州大学 | 取代吡咯烷-2-酮的新合成方法 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3714153A (en) * | 1970-06-22 | 1973-01-30 | Roussel Uclaf | Novel cyclopropanecarboxylic acids |
| DE2329308A1 (de) * | 1972-03-03 | 1975-01-02 | Gruenenthal Chemie | Neue lactame |
| AU518986B2 (en) * | 1977-10-11 | 1981-10-29 | Takeda Chemical Industries Ltd. | Lactams |
| US4138495A (en) * | 1978-05-19 | 1979-02-06 | Stauffer Chemical Company | N-Substituted pyrrolidones and their use as miticides |
| US4440784A (en) * | 1981-02-05 | 1984-04-03 | Kanegafuchi Chemical Industry Company, Ltd. | Anti-inflammatory, analgesic, and antipyretic pharmaceutical composition |
| JPS57130950A (en) * | 1981-02-05 | 1982-08-13 | Kanegafuchi Chem Ind Co Ltd | 3,5-di-tert-butyl-4-hydroxystyrene derivative and anti- inflammatory, analgesic, antipyretic agent and inhibitor for blood platelet aggregation |
| JPS5879944A (ja) * | 1981-11-09 | 1983-05-13 | Kanegafuchi Chem Ind Co Ltd | ３，５−ジ・タ−シヤリ−・ブチルスチレン誘導体及び抗炎症、鎮痛、解熱剤並びに血小板凝集阻害剤 |
| US4431656A (en) * | 1981-02-05 | 1984-02-14 | Kanegafuchi Chemical Industry Company Limited | 3,5-di-Tert-butylstyrene derivatives, salts thereof, and pharmaceutical compositions containing the same as an active ingredient |
| DE3326724A1 (de) * | 1983-07-25 | 1985-02-07 | Boehringer Ingelheim KG, 6507 Ingelheim | In 1-stellung substituierte 4-hydroxymethyl-pyrrolidinone, verfahren zu ihrer herstellung, pharmazeutische zusammensetzungen und zwischenprodukte |
| JPS6112660A (ja) * | 1984-06-27 | 1986-01-21 | Kanegafuchi Chem Ind Co Ltd | 新規２−ピロリドン誘導体及び抗炎症剤 |
| JPH0623194B2 (ja) * | 1985-03-23 | 1994-03-30 | 鐘淵化学工業株式会社 | 新規ラクタム誘導体及び抗炎症剤 |
| JPS6412660A (en) * | 1987-07-07 | 1989-01-17 | Canon Kk | Original reader |
| JP3611676B2 (ja) * | 1996-06-24 | 2005-01-19 | アサマ化成株式会社 | パン生地の改良剤およびパンの製造方法 |
-
1985
- 1985-05-09 JP JP60096799A patent/JPH066571B2/ja not_active Expired - Lifetime
-
1986
- 1986-04-22 FI FI861698A patent/FI84172C/fi not_active IP Right Cessation
- 1986-04-23 US US06/856,068 patent/US4833160A/en not_active Expired - Fee Related
- 1986-04-28 AU AU56766/86A patent/AU581078B2/en not_active Ceased
- 1986-04-30 PH PH33721A patent/PH23189A/en unknown
- 1986-05-05 ZA ZA863352A patent/ZA863352B/xx unknown
- 1986-05-07 AT AT86106249T patent/ATE66673T1/de active
- 1986-05-07 DK DK213286A patent/DK213286A/da not_active Application Discontinuation
- 1986-05-07 NO NO861820A patent/NO861820L/no unknown
- 1986-05-07 DE DE8686106249T patent/DE3681076D1/de not_active Expired - Fee Related
- 1986-05-07 EP EP86106249A patent/EP0204964B1/en not_active Expired - Lifetime
- 1986-05-07 HU HU872041D patent/HU199117B/hu not_active IP Right Cessation
- 1986-05-08 ES ES554775A patent/ES8800148A1/es not_active Expired
- 1986-05-08 HU HU861911A patent/HU196749B/hu not_active IP Right Cessation
- 1986-05-08 MX MX2417A patent/MX162717A/es unknown
- 1986-05-08 NZ NZ216092A patent/NZ216092A/xx unknown
- 1986-05-08 CA CA000508748A patent/CA1264762A/en not_active Expired - Fee Related
- 1986-05-08 PT PT82540A patent/PT82540B/pt not_active IP Right Cessation
- 1986-05-09 KR KR1019860003628A patent/KR910004789B1/ko not_active IP Right Cessation
- 1986-05-09 CN CN86103227A patent/CN1014058B/zh not_active Expired
-
1987
- 1987-05-27 PH PH35306A patent/PH23225A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUT45493A (en) | 1988-07-28 |
| NZ216092A (en) | 1988-08-30 |
| AU5676686A (en) | 1986-11-13 |
| DE3681076D1 (de) | 1991-10-02 |
| DK213286D0 (da) | 1986-05-07 |
| PH23189A (en) | 1989-05-29 |
| ES8800148A1 (es) | 1987-11-01 |
| CN86103227A (zh) | 1987-01-21 |
| JPH066571B2 (ja) | 1994-01-26 |
| FI84172B (fi) | 1991-07-15 |
| MX162717A (es) | 1991-02-18 |
| ATE66673T1 (de) | 1991-09-15 |
| ZA863352B (en) | 1986-12-30 |
| US4833160A (en) | 1989-05-23 |
| DK213286A (da) | 1986-11-10 |
| CN1014058B (zh) | 1991-09-25 |
| EP0204964B1 (en) | 1991-08-28 |
| PT82540B (pt) | 1988-08-17 |
| FI84172C (fi) | 1991-10-25 |
| FI861698A0 (fi) | 1986-04-22 |
| HU199117B (en) | 1990-01-29 |
| CA1264762A (en) | 1990-01-23 |
| PT82540A (en) | 1986-06-01 |
| JPS61257967A (ja) | 1986-11-15 |
| HU196749B (en) | 1989-01-30 |
| AU581078B2 (en) | 1989-02-09 |
| ES554775A0 (es) | 1987-11-01 |
| KR860008973A (ko) | 1986-12-19 |
| KR910004789B1 (ko) | 1991-07-13 |
| EP0204964A1 (en) | 1986-12-17 |
| HUT43040A (en) | 1987-09-28 |
| PH23225A (en) | 1989-06-06 |
| FI861698A (fi) | 1986-11-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO861820L (no) | Fremgangsmaate for fremstilling av 2-pyrrolidon-derivater. | |
| DK0595610T3 (da) | Benzokondenserede lactamer | |
| NO914092D0 (no) | Fremgangsmaate for fremstilling av mercaptoacetylamidderivater | |
| IL97403A0 (en) | 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones,oxazolidinones,and imidazolidinones and pharmaceutical compositions containing them | |
| AU583651B2 (en) | Novel nitromethylene derivatives | |
| ES2133430T3 (es) | Derivados de n-heteroaril-n-fenilurea, su preparacion y utilizacion. | |
| MX9102582A (es) | Derivados de indol 3,7-disubstituidos, procedimiento para su preparacion y composicion farmaceutica que los contiene. | |
| NZ233735A (en) | Heterocyclic substituted aminophenol derivatives | |
| ATE93838T1 (de) | Triphenylmethan-derivate. | |
| ATE112558T1 (de) | Glycosidasehemmer. | |
| DE3682541D1 (de) | Herbizid wirkende derivate des n-phenyl-3,4,5,6-tetrahydrophthalsaeureimides. | |
| ATE230391T1 (de) | Pyrrolidin derivate, anti-ulcus und antibakterielle arzneimittel | |
| FI96856C (fi) | Menetelmä terapeuttisesti käyttökelpoisten aminoketonijohdannaisten valmistamiseksi | |
| JPS5430184A (en) | 3,4-dihydrocarbostyril derivative | |
| IL55048A0 (en) | Cyclized derivatives of n-(2-hydroxyalkyl)-n-phosphonomethylglycine compounds | |
| FI912382A0 (fi) | Menetelmä heterosyklisten NMDA-antagonistien valmistamiseksi | |
| ES2039270T3 (es) | Derivados de gamma-l-glutamil-4-nitroanilida y procedimiento para determinar actividad de gamma-gtp utilizandolos. | |
| NO171635C (no) | Analogifremgangsmaate til fremstilling av et alkysulfonamidofenylalkylamin som er n-substituert over en metylenkjedemed en heterocyklisk gruppe |