NO860414L - Fluorholdige n-sulfenylerte indazoler, fremgangsmaate til deres fremstilling samt deres anvendelse. - Google Patents
Fluorholdige n-sulfenylerte indazoler, fremgangsmaate til deres fremstilling samt deres anvendelse.Info
- Publication number
- NO860414L NO860414L NO860414A NO860414A NO860414L NO 860414 L NO860414 L NO 860414L NO 860414 A NO860414 A NO 860414A NO 860414 A NO860414 A NO 860414A NO 860414 L NO860414 L NO 860414L
- Authority
- NO
- Norway
- Prior art keywords
- fluorine
- halogen
- optionally
- stands
- indazoles
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims description 15
- 238000002360 preparation method Methods 0.000 title claims description 3
- BAXOFTOLAUCFNW-UHFFFAOYSA-N 1H-indazole Chemical compound C1=CC=C2C=NNC2=C1 BAXOFTOLAUCFNW-UHFFFAOYSA-N 0.000 title description 2
- 229910052731 fluorine Inorganic materials 0.000 claims description 29
- 239000011737 fluorine Substances 0.000 claims description 29
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 claims description 25
- 239000013543 active substance Substances 0.000 claims description 23
- -1 fluorine-substituted carbon atom Chemical group 0.000 claims description 21
- 150000002473 indoazoles Chemical class 0.000 claims description 20
- 229910052736 halogen Inorganic materials 0.000 claims description 18
- 150000002367 halogens Chemical class 0.000 claims description 18
- 239000000463 material Substances 0.000 claims description 15
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 claims description 12
- 125000003545 alkoxy group Chemical group 0.000 claims description 7
- 125000001424 substituent group Chemical group 0.000 claims description 7
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- 125000005842 heteroatom Chemical group 0.000 claims description 5
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- 125000000547 substituted alkyl group Chemical group 0.000 claims description 5
- 239000002253 acid Substances 0.000 claims description 4
- 125000004432 carbon atom Chemical group C* 0.000 claims description 4
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- 235000019341 magnesium sulphate Nutrition 0.000 description 4
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
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- YXUMGPCNHDVHBV-UHFFFAOYSA-N 6-(trifluoromethoxy)-1h-indazole Chemical compound FC(F)(F)OC1=CC=C2C=NNC2=C1 YXUMGPCNHDVHBV-UHFFFAOYSA-N 0.000 description 3
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- 229910021578 Iron(III) chloride Inorganic materials 0.000 description 2
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- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 239000008272 agar Substances 0.000 description 2
- 150000001298 alcohols Chemical class 0.000 description 2
- 125000000217 alkyl group Chemical group 0.000 description 2
- 235000019270 ammonium chloride Nutrition 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- LLEMOWNGBBNAJR-UHFFFAOYSA-N biphenyl-2-ol Chemical compound OC1=CC=CC=C1C1=CC=CC=C1 LLEMOWNGBBNAJR-UHFFFAOYSA-N 0.000 description 2
- 238000009835 boiling Methods 0.000 description 2
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- 125000001028 difluoromethyl group Chemical group [H]C(F)(F)* 0.000 description 2
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 2
- 201000010099 disease Diseases 0.000 description 2
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- ZAIRCVNISFRBHW-UHFFFAOYSA-N 1h-benzimidazol-2-yl n-methylcarbamate Chemical class C1=CC=C2NC(OC(=O)NC)=NC2=C1 ZAIRCVNISFRBHW-UHFFFAOYSA-N 0.000 description 1
- 229940061334 2-phenylphenol Drugs 0.000 description 1
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- 239000007858 starting material Substances 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 125000004434 sulfur atom Chemical group 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 description 1
- 239000004753 textile Substances 0.000 description 1
- 150000003613 toluenes Chemical class 0.000 description 1
- 150000004992 toluidines Chemical class 0.000 description 1
- 125000003866 trichloromethyl group Chemical group ClC(Cl)(Cl)* 0.000 description 1
- 125000005034 trifluormethylthio group Chemical group FC(S*)(F)F 0.000 description 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 description 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 description 1
- RQYLOOVORNJDQX-UHFFFAOYSA-N trifluoromethyl thiohypochlorite Chemical compound FC(F)(F)SCl RQYLOOVORNJDQX-UHFFFAOYSA-N 0.000 description 1
- 150000003751 zinc Chemical class 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19853505905 DE3505905A1 (de) | 1985-02-21 | 1985-02-21 | Fluorhaltige n-sulfenylierte indazole, verfahren zu ihrer herstellung sowie ihre verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO860414L true NO860414L (no) | 1986-08-22 |
Family
ID=6263063
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO860414A NO860414L (no) | 1985-02-21 | 1986-02-06 | Fluorholdige n-sulfenylerte indazoler, fremgangsmaate til deres fremstilling samt deres anvendelse. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4778511A (fr) |
| EP (1) | EP0195238B1 (fr) |
| JP (1) | JPS61194076A (fr) |
| CA (1) | CA1275290C (fr) |
| DE (2) | DE3505905A1 (fr) |
| DK (1) | DK79386A (fr) |
| FI (1) | FI860737A (fr) |
| NO (1) | NO860414L (fr) |
| ZA (1) | ZA861267B (fr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1403255A4 (fr) * | 2001-06-12 | 2005-04-06 | Sumitomo Pharma | Inhibiteurs de rho kinase |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3867540A (en) * | 1966-08-22 | 1975-02-18 | Chevron Res | 1-(Polyhaloakylthio) indazoles as fungicidal and bactericidal agents |
| NL129624C (fr) * | 1966-08-22 | |||
| US3637736A (en) * | 1966-10-25 | 1972-01-25 | Tenneco Chem | N'-substituted-6-nitroindazoles |
| US3786152A (en) * | 1966-10-25 | 1974-01-15 | Tenneco Chem | Surface-coating compositions containing n'-trichloromethylmercaptoindazoles |
-
1985
- 1985-02-21 DE DE19853505905 patent/DE3505905A1/de not_active Withdrawn
-
1986
- 1986-02-06 NO NO860414A patent/NO860414L/no unknown
- 1986-02-11 EP EP86101727A patent/EP0195238B1/fr not_active Expired
- 1986-02-11 DE DE8686101727T patent/DE3662595D1/de not_active Expired
- 1986-02-17 JP JP61031022A patent/JPS61194076A/ja active Pending
- 1986-02-18 US US06/830,593 patent/US4778511A/en not_active Expired - Fee Related
- 1986-02-19 FI FI860737A patent/FI860737A/fi not_active Application Discontinuation
- 1986-02-19 CA CA000502215A patent/CA1275290C/fr not_active Expired - Lifetime
- 1986-02-20 DK DK79386A patent/DK79386A/da unknown
- 1986-02-20 ZA ZA861267A patent/ZA861267B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0195238B1 (fr) | 1989-03-29 |
| FI860737A0 (fi) | 1986-02-19 |
| CA1275290C (fr) | 1990-10-16 |
| DK79386A (da) | 1986-08-22 |
| DE3662595D1 (en) | 1989-05-03 |
| DE3505905A1 (de) | 1986-08-21 |
| FI860737A (fi) | 1986-08-22 |
| ZA861267B (en) | 1986-10-29 |
| US4778511A (en) | 1988-10-18 |
| DK79386D0 (da) | 1986-02-20 |
| JPS61194076A (ja) | 1986-08-28 |
| EP0195238A1 (fr) | 1986-09-24 |
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