NO335995B1 - Polypeptider involvert i spiramycin biosyntese, nukleotidsekvenser kodende nevnte polypeptider og anvendelser derav. - Google Patents
Polypeptider involvert i spiramycin biosyntese, nukleotidsekvenser kodende nevnte polypeptider og anvendelser derav.Info
- Publication number
- NO335995B1 NO335995B1 NO20052160A NO20052160A NO335995B1 NO 335995 B1 NO335995 B1 NO 335995B1 NO 20052160 A NO20052160 A NO 20052160A NO 20052160 A NO20052160 A NO 20052160A NO 335995 B1 NO335995 B1 NO 335995B1
- Authority
- NO
- Norway
- Prior art keywords
- gene
- sequence
- strain
- spiramycin
- cassette
- Prior art date
Links
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Classifications
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/36—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Actinomyces; from Streptomyces (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
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- Proteomics, Peptides & Aminoacids (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0212489A FR2845394A1 (fr) | 2002-10-08 | 2002-10-08 | Polypeptides impliques dans la biosynthese des spiramycines, sequences nucleotidiques codant ces polypeptides et leurs applications |
| FR0302439A FR2851773A1 (fr) | 2003-02-27 | 2003-02-27 | Polypeptides impliques dans la biosynthese des spiramycines, sequences nucleotidiques codant ces polypeptides et leurs applications |
| US49349003P | 2003-08-07 | 2003-08-07 | |
| PCT/FR2003/002962 WO2004033689A2 (fr) | 2002-10-08 | 2003-10-08 | Polypeptides impliques dans la biosynthese des spiramycines, sequences nucleotidiques codant ces polypeptides et leurs applications. |
Publications (2)
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| NO20052160L NO20052160L (no) | 2005-06-02 |
| NO335995B1 true NO335995B1 (no) | 2015-04-13 |
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| NO20052160A NO335995B1 (no) | 2002-10-08 | 2005-05-02 | Polypeptider involvert i spiramycin biosyntese, nukleotidsekvenser kodende nevnte polypeptider og anvendelser derav. |
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| EP (1) | EP1551975A2 (ko) |
| JP (1) | JP5042497B2 (ko) |
| KR (1) | KR101110175B1 (ko) |
| AU (1) | AU2003300479B2 (ko) |
| BR (1) | BRPI0314543B8 (ko) |
| CA (1) | CA2501445C (ko) |
| IL (1) | IL167854A (ko) |
| MX (1) | MXPA05002852A (ko) |
| NO (1) | NO335995B1 (ko) |
| WO (1) | WO2004033689A2 (ko) |
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| CN111349595A (zh) * | 2018-12-20 | 2020-06-30 | 沈阳福洋医药科技有限公司 | 一种螺旋霉素产生菌、可利霉素产生菌、构建方法、应用及提高产物产量的方法 |
| WO2024074637A1 (en) * | 2022-10-07 | 2024-04-11 | Syngenta Crop Protection Ag | Means and methods for controlling pathogens and pests in plants |
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| US5068189A (en) * | 1988-05-13 | 1991-11-26 | Eli Lilly And Company | Recombinant dna vectors encoding a 4"-o-isovaleryl acylase derived from a carbomycin biosynthetic gene, designated care, for use in streptomyces and other organisms |
| JP2749616B2 (ja) | 1988-05-24 | 1998-05-13 | メルシャン株式会社 | マクロライド抗生物質の４”位アシル化酵素をコードする遺伝子 |
| US5098837A (en) | 1988-06-07 | 1992-03-24 | Eli Lilly And Company | Macrolide biosynthetic genes for use in streptomyces and other organisms |
| US5322937A (en) * | 1990-06-01 | 1994-06-21 | Mercian Corporation | Genes encoding a 3-acylation enzyme for macrolide antibiotics |
| US5514544A (en) * | 1991-07-26 | 1996-05-07 | Eli Lilly And Company | Activator gene for macrolide biosynthesis |
| JPH0638750A (ja) * | 1991-08-09 | 1994-02-15 | Meiji Seika Kaisha Ltd | マクロライド抗生物質の３位アシル化酵素およびそれをコードする遺伝子 |
| JPH06121677A (ja) * | 1992-01-23 | 1994-05-06 | Mercian Corp | マクロライド抗生物質のアシル化酵素遺伝子の高発現方法 |
| CA2197160C (en) * | 1996-02-22 | 2007-05-01 | Stanley Gene Burgett | Platenolide synthase gene |
| CA2197524A1 (en) * | 1996-02-22 | 1997-08-22 | Bradley Stuart Dehoff | Polyketide synthase genes |
| WO1999005283A2 (fr) * | 1997-07-25 | 1999-02-04 | Hoechst Marion Roussel | Genes de biosynthese et de transfert des 6-desoxyhexoses chez saccharopolyspora erythraea et chez streptomyces antibioticus et leur utilisation |
| US20030113874A1 (en) * | 2001-07-26 | 2003-06-19 | Farnet Chris M. | Genes and proteins for the biosynthesis of rosaramicin |
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2003
- 2003-10-08 KR KR1020057006111A patent/KR101110175B1/ko active IP Right Grant
- 2003-10-08 JP JP2005500990A patent/JP5042497B2/ja not_active Expired - Lifetime
- 2003-10-08 EP EP03807883A patent/EP1551975A2/fr not_active Withdrawn
- 2003-10-08 AU AU2003300479A patent/AU2003300479B2/en not_active Expired
- 2003-10-08 WO PCT/FR2003/002962 patent/WO2004033689A2/fr active Application Filing
- 2003-10-08 CA CA2501445A patent/CA2501445C/fr not_active Expired - Lifetime
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- 2005-05-02 NO NO20052160A patent/NO335995B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0314543B8 (pt) | 2021-05-25 |
| EP1551975A2 (fr) | 2005-07-13 |
| BR0314543A (pt) | 2005-08-09 |
| NO20052160L (no) | 2005-06-02 |
| CA2501445A1 (fr) | 2004-04-22 |
| AU2003300479A1 (en) | 2004-05-04 |
| KR101110175B1 (ko) | 2012-07-18 |
| BRPI0314543B1 (pt) | 2016-06-14 |
| JP2006501863A (ja) | 2006-01-19 |
| AU2003300479B2 (en) | 2009-12-10 |
| WO2004033689A2 (fr) | 2004-04-22 |
| JP5042497B2 (ja) | 2012-10-03 |
| KR20050084843A (ko) | 2005-08-29 |
| IL167854A (en) | 2011-06-30 |
| WO2004033689A3 (fr) | 2004-08-26 |
| MXPA05002852A (es) | 2005-10-05 |
| CA2501445C (fr) | 2016-01-26 |
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