NO333162B1 - Anvendelse av GE 2270 faktor A3-amidderivat for behandling av akne. - Google Patents
Anvendelse av GE 2270 faktor A3-amidderivat for behandling av akne. Download PDFInfo
- Publication number
- NO333162B1 NO333162B1 NO20040662A NO20040662A NO333162B1 NO 333162 B1 NO333162 B1 NO 333162B1 NO 20040662 A NO20040662 A NO 20040662A NO 20040662 A NO20040662 A NO 20040662A NO 333162 B1 NO333162 B1 NO 333162B1
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- Norway
- Prior art keywords
- acne
- use according
- pharmaceutically acceptable
- medicament
- compound
- Prior art date
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- KXGVEGMKQFWNSR-UHFFFAOYSA-N deoxycholic acid Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)C(O)C2 KXGVEGMKQFWNSR-UHFFFAOYSA-N 0.000 description 1
- 210000004207 dermis Anatomy 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 208000035475 disorder Diseases 0.000 description 1
- 239000000975 dye Substances 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000002996 emotional effect Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 210000002919 epithelial cell Anatomy 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 239000000262 estrogen Substances 0.000 description 1
- 229940011871 estrogen Drugs 0.000 description 1
- BEFDCLMNVWHSGT-UHFFFAOYSA-N ethenylcyclopentane Chemical compound C=CC1CCCC1 BEFDCLMNVWHSGT-UHFFFAOYSA-N 0.000 description 1
- 230000004090 etiopathogenesis Effects 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 235000011087 fumaric acid Nutrition 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 244000053095 fungal pathogen Species 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- 239000003163 gonadal steroid hormone Substances 0.000 description 1
- 239000003906 humectant Substances 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 230000009610 hypersensitivity Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 229960005280 isotretinoin Drugs 0.000 description 1
- 229940033355 lauric acid Drugs 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 description 1
- 239000011976 maleic acid Substances 0.000 description 1
- 238000007726 management method Methods 0.000 description 1
- 230000010534 mechanism of action Effects 0.000 description 1
- 230000002175 menstrual effect Effects 0.000 description 1
- 229940098779 methanesulfonic acid Drugs 0.000 description 1
- WBYWAXJHAXSJNI-UHFFFAOYSA-N methyl p-hydroxycinnamate Natural products OC(=O)C=CC1=CC=CC=C1 WBYWAXJHAXSJNI-UHFFFAOYSA-N 0.000 description 1
- 150000007522 mineralic acids Chemical class 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- 239000005445 natural material Substances 0.000 description 1
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 150000007524 organic acids Chemical class 0.000 description 1
- 238000012261 overproduction Methods 0.000 description 1
- WLJNZVDCPSBLRP-UHFFFAOYSA-N pamoic acid Chemical compound C1=CC=C2C(CC=3C4=CC=CC=C4C=C(C=3O)C(=O)O)=C(O)C(C(O)=O)=CC2=C1 WLJNZVDCPSBLRP-UHFFFAOYSA-N 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000001991 pathophysiological effect Effects 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 230000004962 physiological condition Effects 0.000 description 1
- OXNIZHLAWKMVMX-UHFFFAOYSA-N picric acid Chemical compound OC1=C([N+]([O-])=O)C=C([N+]([O-])=O)C=C1[N+]([O-])=O OXNIZHLAWKMVMX-UHFFFAOYSA-N 0.000 description 1
- 229940068918 polyethylene glycol 400 Drugs 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000000770 proinflammatory effect Effects 0.000 description 1
- 239000003642 reactive oxygen metabolite Substances 0.000 description 1
- 150000004492 retinoid derivatives Chemical class 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 210000001732 sebaceous gland Anatomy 0.000 description 1
- 238000009097 single-agent therapy Methods 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 206010040872 skin infection Diseases 0.000 description 1
- 230000036556 skin irritation Effects 0.000 description 1
- 231100000475 skin irritation Toxicity 0.000 description 1
- 230000036555 skin type Effects 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000004334 sorbic acid Substances 0.000 description 1
- 235000010199 sorbic acid Nutrition 0.000 description 1
- 229940075582 sorbic acid Drugs 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 229960004274 stearic acid Drugs 0.000 description 1
- IHCDKJZZFOUARO-UHFFFAOYSA-M sulfacetamide sodium Chemical compound O.[Na+].CC(=O)[N-]S(=O)(=O)C1=CC=C(N)C=C1 IHCDKJZZFOUARO-UHFFFAOYSA-M 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 230000009885 systemic effect Effects 0.000 description 1
- 238000009121 systemic therapy Methods 0.000 description 1
- 239000011975 tartaric acid Substances 0.000 description 1
- 235000002906 tartaric acid Nutrition 0.000 description 1
- 229960001367 tartaric acid Drugs 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
- 229950002929 trinitrophenol Drugs 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP02013268 | 2002-06-17 | ||
| PCT/EP2003/005989 WO2003105881A1 (fr) | 2002-06-17 | 2003-06-06 | Utilisation de derives amido du ge 2270 facteur a3 pour le traitement de l'acne |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20040662L NO20040662L (no) | 2004-04-05 |
| NO333162B1 true NO333162B1 (no) | 2013-03-25 |
Family
ID=29724391
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20040662A NO333162B1 (no) | 2002-06-17 | 2004-02-16 | Anvendelse av GE 2270 faktor A3-amidderivat for behandling av akne. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US7655676B2 (fr) |
| EP (1) | EP1553967B1 (fr) |
| JP (1) | JP4723857B2 (fr) |
| KR (1) | KR20050026401A (fr) |
| AR (1) | AR039682A1 (fr) |
| AT (1) | ATE509633T1 (fr) |
| AU (1) | AU2003242647B2 (fr) |
| BR (1) | BR0305070A (fr) |
| CA (1) | CA2489705C (fr) |
| CY (1) | CY1111734T1 (fr) |
| DK (1) | DK1553967T3 (fr) |
| ES (1) | ES2364269T3 (fr) |
| HK (1) | HK1074402A1 (fr) |
| NO (1) | NO333162B1 (fr) |
| PT (1) | PT1553967E (fr) |
| SI (1) | SI1553967T1 (fr) |
| TW (1) | TWI329650B (fr) |
| WO (1) | WO2003105881A1 (fr) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PE20121011A1 (es) | 2006-05-31 | 2012-08-25 | Novartis Ag | AMINOTIAZOLES COMO MODULADORES DEL FACTOR DE ELONGACION EF-Tu |
| CN101563353B (zh) | 2006-12-20 | 2012-06-27 | 诺瓦提斯公司 | 氨基噻唑大环类、它们作为抗菌化合物的用途以及制备它们的方法 |
| NZ581917A (en) * | 2007-06-04 | 2011-04-29 | Novartis Ag | Macrocylces and their uses |
| JP5286366B2 (ja) | 2007-12-12 | 2013-09-11 | ノバルティス アーゲー | アミノチアゾール類およびその使用 |
| PT106679B (pt) | 2012-11-27 | 2015-03-25 | Hovione Farmaciencia Sa | Formulações tópicas de tetraciclinas, sua preparação e usos |
| FR3004939B1 (fr) * | 2013-04-26 | 2015-05-22 | Oreal | Huile essentielle de satureja montana a forte teneur en geraniol, et utilisation pour traiter les peaux grasses et/ou les defauts esthetiques associes |
| DE102013215828A1 (de) * | 2013-08-09 | 2015-02-12 | Beiersdorf Ag | Gelförmiges Sonnenschutzmittel mit Fettalkoholen |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| LU86865A1 (fr) * | 1987-05-06 | 1989-01-19 | Oreal | Nouveaux retinoates d'ammonium quaternaires,leur utilisation en cosmetique et en dermopharmacie |
| DE3784738T2 (de) * | 1987-06-12 | 1993-07-08 | Molecular Design Int | Topische vorstufen von arzneimitteln zur behandlung von akne und hautkrankheiten. |
| DK0406745T3 (da) | 1989-07-04 | 1995-02-27 | Lepetit Spa | Antibiotiske GE 2270 faktorer A1, A2, A3 og H |
| JP2693859B2 (ja) | 1990-09-28 | 1997-12-24 | 高砂香料工業株式会社 | 尋常性▲ざ▼瘡用皮膚外用剤 |
| IL100572A (en) | 1991-01-03 | 1997-01-10 | Lepetit Spa | Amides of antibiotic ge 2270 factors their preparation and pharmaceutical compositions containing them |
| JP2907640B2 (ja) | 1992-06-29 | 1999-06-21 | 高砂香料工業株式会社 | 尋常性ざ瘡用皮膚外用剤 |
| JP2937667B2 (ja) | 1992-11-19 | 1999-08-23 | 高砂香料工業株式会社 | 尋常性ざ瘡用皮膚外用剤 |
| DK0801655T3 (da) | 1995-02-07 | 1999-02-08 | Biosearch Italia Spa | Basiske prolinamidderivater af GE 2270 og GE 2270-lignende antibiotika |
| KR19990082541A (ko) * | 1996-02-14 | 1999-11-25 | 클라우디오 쿼르타 | 항생물질 ge2270 c2a, d2 및 e 인자의 유도체 |
| AUPN892496A0 (en) * | 1996-03-25 | 1996-04-18 | Technical Consultancy Services Pty Limited | Acne treatment |
| US6009225A (en) * | 1998-05-26 | 1999-12-28 | Ray; Craig D. | Fiber optic drop splice closure and related methods |
-
2003
- 2003-06-06 BR BR0305070-0A patent/BR0305070A/pt not_active Application Discontinuation
- 2003-06-06 PT PT03759919T patent/PT1553967E/pt unknown
- 2003-06-06 JP JP2004512782A patent/JP4723857B2/ja not_active Expired - Fee Related
- 2003-06-06 WO PCT/EP2003/005989 patent/WO2003105881A1/fr active Application Filing
- 2003-06-06 EP EP03759919A patent/EP1553967B1/fr not_active Expired - Lifetime
- 2003-06-06 KR KR1020047020329A patent/KR20050026401A/ko not_active Application Discontinuation
- 2003-06-06 DK DK03759919.8T patent/DK1553967T3/da active
- 2003-06-06 SI SI200332001T patent/SI1553967T1/sl unknown
- 2003-06-06 US US10/518,802 patent/US7655676B2/en active Active
- 2003-06-06 AU AU2003242647A patent/AU2003242647B2/en not_active Ceased
- 2003-06-06 CA CA2489705A patent/CA2489705C/fr not_active Expired - Fee Related
- 2003-06-06 AT AT03759919T patent/ATE509633T1/de active
- 2003-06-06 ES ES03759919T patent/ES2364269T3/es not_active Expired - Lifetime
- 2003-06-12 TW TW092115959A patent/TWI329650B/zh not_active IP Right Cessation
- 2003-06-17 AR ARP030102134A patent/AR039682A1/es not_active Application Discontinuation
-
2004
- 2004-02-16 NO NO20040662A patent/NO333162B1/no not_active IP Right Cessation
-
2005
- 2005-09-20 HK HK05108210.2A patent/HK1074402A1/xx not_active IP Right Cessation
-
2011
- 2011-08-04 CY CY20111100749T patent/CY1111734T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PT1553967E (pt) | 2011-08-01 |
| CY1111734T1 (el) | 2015-10-07 |
| WO2003105881A1 (fr) | 2003-12-24 |
| BR0305070A (pt) | 2004-09-21 |
| AR039682A1 (es) | 2005-03-09 |
| JP4723857B2 (ja) | 2011-07-13 |
| HK1074402A1 (en) | 2005-11-11 |
| CA2489705A1 (fr) | 2003-12-24 |
| NO20040662L (no) | 2004-04-05 |
| CA2489705C (fr) | 2012-08-14 |
| EP1553967A1 (fr) | 2005-07-20 |
| US7655676B2 (en) | 2010-02-02 |
| US20070117825A1 (en) | 2007-05-24 |
| KR20050026401A (ko) | 2005-03-15 |
| DK1553967T3 (da) | 2011-08-29 |
| ES2364269T3 (es) | 2011-08-30 |
| AU2003242647A1 (en) | 2003-12-31 |
| TW200402425A (en) | 2004-02-16 |
| JP2005529947A (ja) | 2005-10-06 |
| TWI329650B (en) | 2010-09-01 |
| SI1553967T1 (sl) | 2011-07-29 |
| AU2003242647B2 (en) | 2009-10-22 |
| ATE509633T1 (de) | 2011-06-15 |
| EP1553967B1 (fr) | 2011-05-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM1K | Lapsed by not paying the annual fees |