NO330897B1 - Fremgangsmate for fremstilling av et protein, der proteinet er et fragment av et protein som er et primaert translatertprodukt av et malgen som enten er C- eller N-terminalen idet primaere translaterte produkt fra et malgen, og derfragmentet har en biologisk funksjon - Google Patents

Fremgangsmate for fremstilling av et protein, der proteinet er et fragment av et protein som er et primaert translatertprodukt av et malgen som enten er C- eller N-terminalen idet primaere translaterte produkt fra et malgen, og derfragmentet har en biologisk funksjon

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Publication number
NO330897B1
NO330897B1 NO20030443A NO20030443A NO330897B1 NO 330897 B1 NO330897 B1 NO 330897B1 NO 20030443 A NO20030443 A NO 20030443A NO 20030443 A NO20030443 A NO 20030443A NO 330897 B1 NO330897 B1 NO 330897B1
Authority
NO
Norway
Prior art keywords
protein
malgene
fragment
product
terminus
Prior art date
Application number
NO20030443A
Other languages
English (en)
Norwegian (no)
Other versions
NO20030443L (no
NO20030443D0 (no
Inventor
Giampiero De Luca
Luca Falciola
Original Assignee
Serono Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Serono Lab filed Critical Serono Lab
Publication of NO20030443D0 publication Critical patent/NO20030443D0/no
Publication of NO20030443L publication Critical patent/NO20030443L/no
Publication of NO330897B1 publication Critical patent/NO330897B1/no

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
    • C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
NO20030443A 2000-08-01 2003-01-28 Fremgangsmate for fremstilling av et protein, der proteinet er et fragment av et protein som er et primaert translatertprodukt av et malgen som enten er C- eller N-terminalen idet primaere translaterte produkt fra et malgen, og derfragmentet har en biologisk funksjon NO330897B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0018876.3A GB0018876D0 (en) 2000-08-01 2000-08-01 Method of producing polypeptides
PCT/GB2001/003455 WO2002010372A1 (en) 2000-08-01 2001-08-01 Method of producing functional protein domains

Publications (3)

Publication Number Publication Date
NO20030443D0 NO20030443D0 (no) 2003-01-28
NO20030443L NO20030443L (no) 2003-03-25
NO330897B1 true NO330897B1 (no) 2011-08-08

Family

ID=9896767

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20030443A NO330897B1 (no) 2000-08-01 2003-01-28 Fremgangsmate for fremstilling av et protein, der proteinet er et fragment av et protein som er et primaert translatertprodukt av et malgen som enten er C- eller N-terminalen idet primaere translaterte produkt fra et malgen, og derfragmentet har en biologisk funksjon

Country Status (21)

Country Link
US (1) US8048645B2 (el)
EP (1) EP1305411B1 (el)
JP (1) JP5068916B2 (el)
CN (1) CN1468304B (el)
AR (1) AR031717A1 (el)
AT (1) ATE398174T1 (el)
AU (1) AU7573901A (el)
BR (1) BR0112979A (el)
CA (1) CA2415768C (el)
CY (1) CY1110431T1 (el)
DE (1) DE60134410D1 (el)
DK (1) DK1305411T3 (el)
ES (1) ES2305091T3 (el)
GB (1) GB0018876D0 (el)
HK (1) HK1059281A1 (el)
IL (1) IL154212A0 (el)
NO (1) NO330897B1 (el)
PT (1) PT1305411E (el)
SI (1) SI1305411T1 (el)
WO (1) WO2002010372A1 (el)
ZA (1) ZA200300827B (el)

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CN103502448B (zh) 2010-11-12 2017-03-29 Gen9股份有限公司 核酸合成的方法和设备
WO2013032850A2 (en) 2011-08-26 2013-03-07 Gen9, Inc. Compositions and methods for high fidelity assembly of nucleic acids
US9150853B2 (en) 2012-03-21 2015-10-06 Gen9, Inc. Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis
EP4001427A1 (en) 2012-04-24 2022-05-25 Gen9, Inc. Methods for sorting nucleic acids and multiplexed preparative in vitro cloning
CN113512577A (zh) 2012-06-25 2021-10-19 Gen9股份有限公司 用于核酸组装和高通量测序的方法
KR102291045B1 (ko) 2013-08-05 2021-08-19 트위스트 바이오사이언스 코포레이션 드 노보 합성된 유전자 라이브러리
CA2975855A1 (en) 2015-02-04 2016-08-11 Twist Bioscience Corporation Compositions and methods for synthetic gene assembly
WO2016126882A1 (en) 2015-02-04 2016-08-11 Twist Bioscience Corporation Methods and devices for de novo oligonucleic acid assembly
US9981239B2 (en) 2015-04-21 2018-05-29 Twist Bioscience Corporation Devices and methods for oligonucleic acid library synthesis
US10844373B2 (en) 2015-09-18 2020-11-24 Twist Bioscience Corporation Oligonucleic acid variant libraries and synthesis thereof
CN108698012A (zh) 2015-09-22 2018-10-23 特韦斯特生物科学公司 用于核酸合成的柔性基底
CN115920796A (zh) 2015-12-01 2023-04-07 特韦斯特生物科学公司 功能化表面及其制备
GB2568444A (en) 2016-08-22 2019-05-15 Twist Bioscience Corp De novo synthesized nucleic acid libraries
US10417457B2 (en) 2016-09-21 2019-09-17 Twist Bioscience Corporation Nucleic acid based data storage
CA3047128A1 (en) 2016-12-16 2018-06-21 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
CA3054303A1 (en) 2017-02-22 2018-08-30 Twist Bioscience Corporation Nucleic acid based data storage
WO2018170169A1 (en) 2017-03-15 2018-09-20 Twist Bioscience Corporation Variant libraries of the immunological synapse and synthesis thereof
WO2018231864A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
WO2018231872A1 (en) 2017-06-12 2018-12-20 Twist Bioscience Corporation Methods for seamless nucleic acid assembly
JP2020536504A (ja) 2017-09-11 2020-12-17 ツイスト バイオサイエンス コーポレーション Ｇｐｃｒ結合タンパク質およびその合成
WO2019079769A1 (en) 2017-10-20 2019-04-25 Twist Bioscience Corporation HEATED NANOWELLS FOR THE SYNTHESIS OF POLYNUCLEOTIDES
AU2019205269A1 (en) 2018-01-04 2020-07-30 Twist Bioscience Corporation DNA-based digital information storage
SG11202011467RA (en) 2018-05-18 2020-12-30 Twist Bioscience Corp Polynucleotides, reagents, and methods for nucleic acid hybridization
SG11202109283UA (en) 2019-02-26 2021-09-29 Twist Bioscience Corp Variant nucleic acid libraries for antibody optimization
CN113766930A (zh) 2019-02-26 2021-12-07 特韦斯特生物科学公司 Glp1受体的变异核酸文库
EP3987019A4 (en) 2019-06-21 2023-04-19 Twist Bioscience Corporation BARCODE-BASED NUCLEIC ACID SEQUENCE ARRANGEMENT
AU2021350195A1 (en) 2020-09-28 2023-05-04 Vestaron Corporation Mu-diguetoxin-dc1a variant polypeptides for pest control
WO2022235929A1 (en) 2021-05-05 2022-11-10 Radius Pharmaceuticals, Inc. Animal model having homologous recombination of mouse pth1 receptor
WO2023122805A1 (en) 2021-12-20 2023-06-29 Vestaron Corporation Sorbitol driven selection pressure method
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Also Published As

Publication number Publication date
WO2002010372A8 (en) 2002-02-28
NO20030443L (no) 2003-03-25
EP1305411A1 (en) 2003-05-02
ES2305091T3 (es) 2008-11-01
DE60134410D1 (de) 2008-07-24
GB0018876D0 (en) 2000-09-20
AU7573901A (en) 2002-02-13
IL154212A0 (en) 2003-07-31
ATE398174T1 (de) 2008-07-15
AR031717A1 (es) 2003-10-01
NO20030443D0 (no) 2003-01-28
WO2002010372A1 (en) 2002-02-07
CA2415768C (en) 2011-05-17
SI1305411T1 (sl) 2008-10-31
CA2415768A1 (en) 2002-02-07
DK1305411T3 (da) 2008-09-01
CN1468304B (zh) 2011-01-19
JP5068916B2 (ja) 2012-11-07
HK1059281A1 (en) 2004-06-25
US20040053362A1 (en) 2004-03-18
ZA200300827B (en) 2004-02-25
US8048645B2 (en) 2011-11-01
BR0112979A (pt) 2003-07-08
EP1305411B1 (en) 2008-06-11
PT1305411E (pt) 2008-07-03
CY1110431T1 (el) 2015-04-29
JP2004504840A (ja) 2004-02-19
CN1468304A (zh) 2004-01-14

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