NO330897B1 - Fremgangsmate for fremstilling av et protein, der proteinet er et fragment av et protein som er et primaert translatertprodukt av et malgen som enten er C- eller N-terminalen idet primaere translaterte produkt fra et malgen, og derfragmentet har en biologisk funksjon - Google Patents
Fremgangsmate for fremstilling av et protein, der proteinet er et fragment av et protein som er et primaert translatertprodukt av et malgen som enten er C- eller N-terminalen idet primaere translaterte produkt fra et malgen, og derfragmentet har en biologisk funksjonInfo
- Publication number
- NO330897B1 NO330897B1 NO20030443A NO20030443A NO330897B1 NO 330897 B1 NO330897 B1 NO 330897B1 NO 20030443 A NO20030443 A NO 20030443A NO 20030443 A NO20030443 A NO 20030443A NO 330897 B1 NO330897 B1 NO 330897B1
- Authority
- NO
- Norway
- Prior art keywords
- protein
- malgene
- fragment
- product
- terminus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Crystallography & Structural Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Mycology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0018876.3A GB0018876D0 (en) | 2000-08-01 | 2000-08-01 | Method of producing polypeptides |
| PCT/GB2001/003455 WO2002010372A1 (en) | 2000-08-01 | 2001-08-01 | Method of producing functional protein domains |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20030443D0 NO20030443D0 (no) | 2003-01-28 |
| NO20030443L NO20030443L (no) | 2003-03-25 |
| NO330897B1 true NO330897B1 (no) | 2011-08-08 |
Family
ID=9896767
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20030443A NO330897B1 (no) | 2000-08-01 | 2003-01-28 | Fremgangsmate for fremstilling av et protein, der proteinet er et fragment av et protein som er et primaert translatertprodukt av et malgen som enten er C- eller N-terminalen idet primaere translaterte produkt fra et malgen, og derfragmentet har en biologisk funksjon |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8048645B2 (no) |
| EP (1) | EP1305411B1 (no) |
| JP (1) | JP5068916B2 (no) |
| CN (1) | CN1468304B (no) |
| AR (1) | AR031717A1 (no) |
| AT (1) | ATE398174T1 (no) |
| AU (1) | AU7573901A (no) |
| BR (1) | BR0112979A (no) |
| CA (1) | CA2415768C (no) |
| CY (1) | CY1110431T1 (no) |
| DE (1) | DE60134410D1 (no) |
| DK (1) | DK1305411T3 (no) |
| ES (1) | ES2305091T3 (no) |
| GB (1) | GB0018876D0 (no) |
| HK (1) | HK1059281A1 (no) |
| IL (1) | IL154212A0 (no) |
| NO (1) | NO330897B1 (no) |
| PT (1) | PT1305411E (no) |
| SI (1) | SI1305411T1 (no) |
| WO (1) | WO2002010372A1 (no) |
| ZA (1) | ZA200300827B (no) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE60312039T2 (de) * | 2002-12-20 | 2007-11-08 | Chromagenics B.V. | Mittel und methoden zur produktion eines proteins durch chromatin-öffner, die chromatin zugänglicher für transkriptionsfaktoren machen können |
| DK1636260T3 (da) * | 2003-06-10 | 2009-06-22 | Biogen Idec Inc | Forbedret udskillelse af Neublastin |
| WO2008027558A2 (en) | 2006-08-31 | 2008-03-06 | Codon Devices, Inc. | Iterative nucleic acid assembly using activation of vector-encoded traits |
| WO2011053957A2 (en) * | 2009-11-02 | 2011-05-05 | Gen9, Inc. | Compositions and methods for the regulation of multiple genes of interest in a cell |
| US9295965B2 (en) | 2010-11-12 | 2016-03-29 | Gen9, Inc. | Methods and devices for nucleic acid synthesis |
| EP2637780B1 (en) | 2010-11-12 | 2022-02-09 | Gen9, Inc. | Protein arrays and methods of using and making the same |
| US20130059296A1 (en) | 2011-08-26 | 2013-03-07 | Gen9, Inc. | Compositions and Methods For High Fidelity Assembly of Nucleic Acids |
| US9150853B2 (en) | 2012-03-21 | 2015-10-06 | Gen9, Inc. | Methods for screening proteins using DNA encoded chemical libraries as templates for enzyme catalysis |
| CA2871505C (en) | 2012-04-24 | 2021-10-12 | Gen9, Inc. | Methods for sorting nucleic acids and multiplexed preparative in vitro cloning |
| US20150191719A1 (en) | 2012-06-25 | 2015-07-09 | Gen9, Inc. | Methods for Nucleic Acid Assembly and High Throughput Sequencing |
| TWI646230B (zh) | 2013-08-05 | 2019-01-01 | 扭轉生物科技有限公司 | 重新合成之基因庫 |
| WO2016126987A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Compositions and methods for synthetic gene assembly |
| CA2975852A1 (en) | 2015-02-04 | 2016-08-11 | Twist Bioscience Corporation | Methods and devices for de novo oligonucleic acid assembly |
| WO2016172377A1 (en) | 2015-04-21 | 2016-10-27 | Twist Bioscience Corporation | Devices and methods for oligonucleic acid library synthesis |
| JP6982362B2 (ja) | 2015-09-18 | 2021-12-17 | ツイスト バイオサイエンス コーポレーション | オリゴ核酸変異体ライブラリーとその合成 |
| CN113604546A (zh) | 2015-09-22 | 2021-11-05 | 特韦斯特生物科学公司 | 用于核酸合成的柔性基底 |
| CN108603307A (zh) | 2015-12-01 | 2018-09-28 | 特韦斯特生物科学公司 | 功能化表面及其制备 |
| AU2017315294B2 (en) | 2016-08-22 | 2023-12-21 | Twist Bioscience Corporation | De novo synthesized nucleic acid libraries |
| CN110248724B (zh) | 2016-09-21 | 2022-11-18 | 特韦斯特生物科学公司 | 基于核酸的数据存储 |
| EA201991262A1 (ru) | 2016-12-16 | 2020-04-07 | Твист Байосайенс Корпорейшн | Библиотеки вариантов иммунологического синапса и их синтез |
| CN110892485B (zh) | 2017-02-22 | 2024-03-22 | 特韦斯特生物科学公司 | 基于核酸的数据存储 |
| US10894959B2 (en) | 2017-03-15 | 2021-01-19 | Twist Bioscience Corporation | Variant libraries of the immunological synapse and synthesis thereof |
| US10696965B2 (en) | 2017-06-12 | 2020-06-30 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| WO2018231864A1 (en) | 2017-06-12 | 2018-12-20 | Twist Bioscience Corporation | Methods for seamless nucleic acid assembly |
| KR20200047706A (ko) | 2017-09-11 | 2020-05-07 | 트위스트 바이오사이언스 코포레이션 | Gpcr 결합 단백질 및 이의 합성 방법 |
| US10894242B2 (en) | 2017-10-20 | 2021-01-19 | Twist Bioscience Corporation | Heated nanowells for polynucleotide synthesis |
| EP3735459A4 (en) | 2018-01-04 | 2021-10-06 | Twist Bioscience Corporation | DNA-BASED DIGITAL INFORMATION STORAGE |
| CN112639130B (zh) | 2018-05-18 | 2024-08-09 | 特韦斯特生物科学公司 | 用于核酸杂交的多核苷酸、试剂和方法 |
| SG11202109322TA (en) | 2019-02-26 | 2021-09-29 | Twist Bioscience Corp | Variant nucleic acid libraries for glp1 receptor |
| CA3131691A1 (en) | 2019-02-26 | 2020-09-03 | Twist Bioscience Corporation | Variant nucleic acid libraries for antibody optimization |
| CA3144644A1 (en) | 2019-06-21 | 2020-12-24 | Twist Bioscience Corporation | Barcode-based nucleic acid sequence assembly |
| KR20220066151A (ko) | 2019-09-23 | 2022-05-23 | 트위스트 바이오사이언스 코포레이션 | Crth2에 대한 변이체 핵산 라이브러리 |
| WO2022067214A2 (en) | 2020-09-28 | 2022-03-31 | Vestaron Corporation | Mu-diguetoxin-dc1a variant polypeptides for pest control |
| CA3217862A1 (en) | 2021-05-05 | 2022-11-10 | Radius Pharmaceuticals, Inc. | Animal model having homologous recombination of mouse pth1 receptor |
| WO2023122805A1 (en) | 2021-12-20 | 2023-06-29 | Vestaron Corporation | Sorbitol driven selection pressure method |
| WO2024026406A2 (en) | 2022-07-29 | 2024-02-01 | Vestaron Corporation | Next Generation ACTX Peptides |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2646438B1 (fr) * | 1989-03-20 | 2007-11-02 | Pasteur Institut | Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration |
| WO1991006666A1 (en) * | 1989-11-06 | 1991-05-16 | Cell Genesys, Inc. | Production of proteins using homologous recombination |
| US5272071A (en) * | 1989-12-22 | 1993-12-21 | Applied Research Systems Ars Holding N.V. | Method for the modification of the expression characteristics of an endogenous gene of a given cell line |
| JP3501286B2 (ja) | 1989-12-22 | 2004-03-02 | アプライド リサーチ システムズ，エーアールエス ホールディング ナームロゼ ベノートスハップ | 一定の細胞系又は微生物の内因性遺伝子の発現特徴の変性のための方法 |
| AU2515992A (en) * | 1991-08-20 | 1993-03-16 | Genpharm International, Inc. | Gene targeting in animal cells using isogenic dna constructs |
| US6063630A (en) * | 1991-11-05 | 2000-05-16 | Transkaryotic Therapies, Inc. | Targeted introduction of DNA into primary or secondary cells and their use for gene therapy |
| US5733761A (en) * | 1991-11-05 | 1998-03-31 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
| US5641670A (en) | 1991-11-05 | 1997-06-24 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
| US6270989B1 (en) * | 1991-11-05 | 2001-08-07 | Transkaryotic Therapies, Inc. | Protein production and delivery |
| TW402639B (en) | 1992-12-03 | 2000-08-21 | Transkaryotic Therapies Inc | Protein production and protein delivery |
| CN1256986C (zh) * | 1993-12-02 | 2006-05-24 | 转移染色体治疗公司 | 蛋白质的生产和蛋白质的输送 |
| US5545817A (en) * | 1994-03-11 | 1996-08-13 | Calgene, Inc. | Enhanced expression in a plant plastid |
| US6229006B1 (en) | 1995-12-22 | 2001-05-08 | Smithkline Beecham Corporation | Use of antisense oligodeoxynucleotides to produce truncated proteins |
| BR9812540A (pt) * | 1997-09-26 | 2001-12-26 | Athersys Inc | Expressão de genes endógenos por recombinaçãonão homóloga de uma construção de vetor comdna celular |
| US7063960B2 (en) * | 1997-12-12 | 2006-06-20 | The Rockefeller University | Protein belonging to the TNF superfamily involved in signal transduction, nucleic acids encoding same, and methods of use thereof |
| CA2323834C (en) * | 1998-03-27 | 2009-01-27 | Lexicon Genetics Incorporated | Vectors for gene mutagenesis and gene discovery |
| US6436707B1 (en) | 1998-03-27 | 2002-08-20 | Lexicon Genetics Incorporated | Vectors for gene mutagenesis and gene discovery |
| JP3688118B2 (ja) | 1998-05-22 | 2005-08-24 | 独立行政法人科学技術振興機構 | 遺伝子トラップ用ベクターと、このベクターを用いた遺伝子トラップ方法 |
-
2000
- 2000-08-01 GB GBGB0018876.3A patent/GB0018876D0/en not_active Ceased
-
2001
- 2001-07-31 AR ARP010103647A patent/AR031717A1/es active IP Right Grant
- 2001-08-01 US US10/343,684 patent/US8048645B2/en not_active Expired - Fee Related
- 2001-08-01 PT PT01953251T patent/PT1305411E/pt unknown
- 2001-08-01 AT AT01953251T patent/ATE398174T1/de active
- 2001-08-01 CA CA2415768A patent/CA2415768C/en not_active Expired - Fee Related
- 2001-08-01 CN CN01816657.1A patent/CN1468304B/zh not_active Expired - Fee Related
- 2001-08-01 ES ES01953251T patent/ES2305091T3/es not_active Expired - Lifetime
- 2001-08-01 BR BR0112979-1A patent/BR0112979A/pt not_active Application Discontinuation
- 2001-08-01 EP EP01953251A patent/EP1305411B1/en not_active Expired - Lifetime
- 2001-08-01 DK DK01953251T patent/DK1305411T3/da active
- 2001-08-01 DE DE60134410T patent/DE60134410D1/de not_active Expired - Lifetime
- 2001-08-01 SI SI200130842T patent/SI1305411T1/sl unknown
- 2001-08-01 WO PCT/GB2001/003455 patent/WO2002010372A1/en active IP Right Grant
- 2001-08-01 IL IL15421201A patent/IL154212A0/xx unknown
- 2001-08-01 JP JP2002516291A patent/JP5068916B2/ja not_active Expired - Fee Related
- 2001-08-01 AU AU7573901A patent/AU7573901A/xx not_active Withdrawn
-
2003
- 2003-01-28 NO NO20030443A patent/NO330897B1/no not_active IP Right Cessation
- 2003-01-30 ZA ZA200300827A patent/ZA200300827B/xx unknown
-
2004
- 2004-03-05 HK HK04101655.0A patent/HK1059281A1/xx not_active IP Right Cessation
-
2008
- 2008-07-11 CY CY20081100728T patent/CY1110431T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1059281A1 (en) | 2004-06-25 |
| NO20030443L (no) | 2003-03-25 |
| AU7573901A (en) | 2002-02-13 |
| CA2415768C (en) | 2011-05-17 |
| CN1468304B (zh) | 2011-01-19 |
| EP1305411A1 (en) | 2003-05-02 |
| EP1305411B1 (en) | 2008-06-11 |
| CY1110431T1 (el) | 2015-04-29 |
| NO20030443D0 (no) | 2003-01-28 |
| ES2305091T3 (es) | 2008-11-01 |
| US8048645B2 (en) | 2011-11-01 |
| JP2004504840A (ja) | 2004-02-19 |
| DE60134410D1 (de) | 2008-07-24 |
| DK1305411T3 (da) | 2008-09-01 |
| ZA200300827B (en) | 2004-02-25 |
| IL154212A0 (en) | 2003-07-31 |
| CA2415768A1 (en) | 2002-02-07 |
| GB0018876D0 (en) | 2000-09-20 |
| CN1468304A (zh) | 2004-01-14 |
| JP5068916B2 (ja) | 2012-11-07 |
| BR0112979A (pt) | 2003-07-08 |
| PT1305411E (pt) | 2008-07-03 |
| AR031717A1 (es) | 2003-10-01 |
| US20040053362A1 (en) | 2004-03-18 |
| ATE398174T1 (de) | 2008-07-15 |
| WO2002010372A1 (en) | 2002-02-07 |
| WO2002010372A8 (en) | 2002-02-28 |
| SI1305411T1 (sl) | 2008-10-31 |
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