NO330697B1 - Implantat som har antibiotisk langtidsvirkning - Google Patents
Implantat som har antibiotisk langtidsvirkning Download PDFInfo
- Publication number
- NO330697B1 NO330697B1 NO20055834A NO20055834A NO330697B1 NO 330697 B1 NO330697 B1 NO 330697B1 NO 20055834 A NO20055834 A NO 20055834A NO 20055834 A NO20055834 A NO 20055834A NO 330697 B1 NO330697 B1 NO 330697B1
- Authority
- NO
- Norway
- Prior art keywords
- layer
- silver
- implant according
- absorbable
- implant
- Prior art date
Links
- 239000007943 implant Substances 0.000 title claims abstract description 48
- 230000007774 longterm Effects 0.000 title claims abstract description 10
- 230000003115 biocidal effect Effects 0.000 title claims abstract description 8
- 229910052709 silver Inorganic materials 0.000 claims abstract description 73
- 239000004332 silver Substances 0.000 claims abstract description 73
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 claims abstract description 66
- 238000000576 coating method Methods 0.000 claims abstract description 26
- 239000011248 coating agent Substances 0.000 claims abstract description 24
- 230000002792 vascular Effects 0.000 claims abstract description 24
- 239000000463 material Substances 0.000 claims abstract description 17
- 239000002861 polymer material Substances 0.000 claims abstract description 12
- -1 argon ions Chemical class 0.000 claims description 13
- 229920000642 polymer Polymers 0.000 claims description 13
- 238000005470 impregnation Methods 0.000 claims description 10
- 239000004753 textile Substances 0.000 claims description 9
- 239000000835 fiber Substances 0.000 claims description 7
- 239000011148 porous material Substances 0.000 claims description 7
- 238000010521 absorption reaction Methods 0.000 claims description 4
- 239000013543 active substance Substances 0.000 claims description 4
- 229920001577 copolymer Polymers 0.000 claims description 4
- 238000001727 in vivo Methods 0.000 claims description 4
- XKRFYHLGVUSROY-UHFFFAOYSA-N argon Substances [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 claims description 3
- 229910052786 argon Inorganic materials 0.000 claims description 3
- 239000012620 biological material Substances 0.000 claims description 3
- 229920000295 expanded polytetrafluoroethylene Polymers 0.000 claims description 3
- 150000001261 hydroxy acids Chemical class 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 210000000056 organ Anatomy 0.000 claims description 2
- 229920001059 synthetic polymer Polymers 0.000 claims description 2
- 208000015181 infectious disease Diseases 0.000 description 15
- 239000008363 phosphate buffer Substances 0.000 description 8
- 238000002513 implantation Methods 0.000 description 6
- 238000007740 vapor deposition Methods 0.000 description 6
- 108010010803 Gelatin Proteins 0.000 description 5
- 229920000159 gelatin Polymers 0.000 description 5
- 239000008273 gelatin Substances 0.000 description 5
- 235000019322 gelatine Nutrition 0.000 description 5
- 235000011852 gelatine desserts Nutrition 0.000 description 5
- 238000000034 method Methods 0.000 description 5
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 210000002808 connective tissue Anatomy 0.000 description 4
- 238000007735 ion beam assisted deposition Methods 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 210000001519 tissue Anatomy 0.000 description 4
- 102000008186 Collagen Human genes 0.000 description 3
- 108010035532 Collagen Proteins 0.000 description 3
- 229920001436 collagen Polymers 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 239000002657 fibrous material Substances 0.000 description 3
- 230000003993 interaction Effects 0.000 description 3
- 229920000728 polyester Polymers 0.000 description 3
- 206010019909 Hernia Diseases 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- 241000283973 Oryctolagus cuniculus Species 0.000 description 2
- 230000002159 abnormal effect Effects 0.000 description 2
- 125000005442 diisocyanate group Chemical group 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 230000000813 microbial effect Effects 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical compound [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 description 2
- 238000007789 sealing Methods 0.000 description 2
- CQLFBEKRDQMJLZ-UHFFFAOYSA-M silver acetate Chemical compound [Ag+].CC([O-])=O CQLFBEKRDQMJLZ-UHFFFAOYSA-M 0.000 description 2
- 229940071536 silver acetate Drugs 0.000 description 2
- VPVXHAANQNHFSF-UHFFFAOYSA-N 1,4-dioxan-2-one Chemical compound O=C1COCCO1 VPVXHAANQNHFSF-UHFFFAOYSA-N 0.000 description 1
- RKDVKSZUMVYZHH-UHFFFAOYSA-N 1,4-dioxane-2,5-dione Chemical compound O=C1COC(=O)CO1 RKDVKSZUMVYZHH-UHFFFAOYSA-N 0.000 description 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 229910001316 Ag alloy Inorganic materials 0.000 description 1
- 102000009027 Albumins Human genes 0.000 description 1
- 108010088751 Albumins Proteins 0.000 description 1
- 229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 1
- 206010064687 Device related infection Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- SXRSQZLOMIGNAQ-UHFFFAOYSA-N Glutaraldehyde Chemical compound O=CCCCC=O SXRSQZLOMIGNAQ-UHFFFAOYSA-N 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000004372 Polyvinyl alcohol Substances 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 241000191940 Staphylococcus Species 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 208000007536 Thrombosis Diseases 0.000 description 1
- 229910045601 alloy Inorganic materials 0.000 description 1
- 239000000956 alloy Substances 0.000 description 1
- 230000003872 anastomosis Effects 0.000 description 1
- 210000000709 aorta Anatomy 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 239000001768 carboxy methyl cellulose Substances 0.000 description 1
- 235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
- 239000008112 carboxymethyl-cellulose Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 229910010293 ceramic material Inorganic materials 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 229910052802 copper Inorganic materials 0.000 description 1
- 239000010949 copper Substances 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 239000004053 dental implant Substances 0.000 description 1
- 230000001419 dependent effect Effects 0.000 description 1
- 210000002615 epidermis Anatomy 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- JBFHTYHTHYHCDJ-UHFFFAOYSA-N gamma-caprolactone Chemical compound CCC1CCC(=O)O1 JBFHTYHTHYHCDJ-UHFFFAOYSA-N 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 210000004394 hip joint Anatomy 0.000 description 1
- 230000003054 hormonal effect Effects 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 229910052741 iridium Inorganic materials 0.000 description 1
- GKOZUEZYRPOHIO-UHFFFAOYSA-N iridium atom Chemical compound [Ir] GKOZUEZYRPOHIO-UHFFFAOYSA-N 0.000 description 1
- 210000000629 knee joint Anatomy 0.000 description 1
- JJTUDXZGHPGLLC-UHFFFAOYSA-N lactide Chemical compound CC1OC(=O)C(C)OC1=O JJTUDXZGHPGLLC-UHFFFAOYSA-N 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 230000003211 malignant effect Effects 0.000 description 1
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 1
- 229910052753 mercury Inorganic materials 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 229910052697 platinum Inorganic materials 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920001343 polytetrafluoroethylene Polymers 0.000 description 1
- 239000004810 polytetrafluoroethylene Substances 0.000 description 1
- 229920002635 polyurethane Polymers 0.000 description 1
- 239000004814 polyurethane Substances 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 150000003378 silver Chemical class 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 230000003313 weakening effect Effects 0.000 description 1
- 239000002759 woven fabric Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/54—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/30—Inorganic materials
- A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L27/507—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials for artificial blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/606—Coatings
- A61L2300/608—Coatings having two or more layers
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/12—All metal or with adjacent metals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/13—Hollow or container type article [e.g., tube, vase, etc.]
- Y10T428/1352—Polymer or resin containing [i.e., natural or synthetic]
- Y10T428/1355—Elemental metal containing [e.g., substrate, foil, film, coating, etc.]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Transplantation (AREA)
- Epidemiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Dermatology (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Vascular Medicine (AREA)
- Inorganic Chemistry (AREA)
- Prostheses (AREA)
- Materials For Medical Uses (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10323676A DE10323676A1 (de) | 2003-05-15 | 2003-05-15 | Implantat mit antibiotischer Langzeitwirkung |
PCT/EP2004/005162 WO2004101010A1 (de) | 2003-05-15 | 2004-05-14 | Implantat mit antibiotischer langzeitwirkung |
Publications (3)
Publication Number | Publication Date |
---|---|
NO20055834D0 NO20055834D0 (no) | 2005-12-08 |
NO20055834L NO20055834L (no) | 2005-12-08 |
NO330697B1 true NO330697B1 (no) | 2011-06-14 |
Family
ID=33394793
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20055834A NO330697B1 (no) | 2003-05-15 | 2005-12-08 | Implantat som har antibiotisk langtidsvirkning |
Country Status (9)
Country | Link |
---|---|
US (1) | US20060051544A1 (pl) |
EP (1) | EP1513563B1 (pl) |
JP (1) | JP2006528893A (pl) |
AT (1) | ATE306950T1 (pl) |
DE (2) | DE10323676A1 (pl) |
ES (1) | ES2252729T3 (pl) |
NO (1) | NO330697B1 (pl) |
PL (1) | PL1513563T3 (pl) |
WO (1) | WO2004101010A1 (pl) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10243132B4 (de) * | 2002-09-17 | 2006-09-14 | Biocer Entwicklungs Gmbh | Antiinfektiöse, biokompatible Titanoxid-Beschichtungen für Implantate sowie Verfahren zu deren Herstellung |
US9012506B2 (en) | 2004-09-28 | 2015-04-21 | Atrium Medical Corporation | Cross-linked fatty acid-based biomaterials |
WO2006036967A1 (en) | 2004-09-28 | 2006-04-06 | Atrium Medical Corporation | Solubilizing a drug for use in a coating |
US8795703B2 (en) * | 2004-09-28 | 2014-08-05 | Atrium Medical Corporation | Stand-alone film and methods for making the same |
US9801982B2 (en) * | 2004-09-28 | 2017-10-31 | Atrium Medical Corporation | Implantable barrier device |
US9000040B2 (en) | 2004-09-28 | 2015-04-07 | Atrium Medical Corporation | Cross-linked fatty acid-based biomaterials |
DE102004051487A1 (de) * | 2004-10-21 | 2006-04-27 | Ethicon Gmbh | Chirurgisches Implantat |
DE102004063794A1 (de) * | 2004-12-30 | 2006-07-13 | Universität Duisburg-Essen | Implantat |
DE102005015174A1 (de) * | 2005-04-02 | 2006-10-05 | Eleonore Dr. Behrens | Dentales Implantat |
DE102005032604A1 (de) * | 2005-07-13 | 2007-01-18 | Gfe Medizintechnik Gmbh | Resorbierbares, in den Körper einsetzbares medizinisches Element, insbesondere resorbierbares Implantat |
US9427423B2 (en) | 2009-03-10 | 2016-08-30 | Atrium Medical Corporation | Fatty-acid based particles |
US9278161B2 (en) | 2005-09-28 | 2016-03-08 | Atrium Medical Corporation | Tissue-separating fatty acid adhesion barrier |
EP2626091B1 (en) * | 2006-11-06 | 2016-09-28 | Atrium Medical Corporation | Coated surgical mesh |
US9492596B2 (en) | 2006-11-06 | 2016-11-15 | Atrium Medical Corporation | Barrier layer with underlying medical device and one or more reinforcing support structures |
DE102007047246A1 (de) | 2007-09-26 | 2009-04-02 | Aesculap Ag | Verstärkte Gefäßprothese mit antimikrobieller Langzeitwirkung |
US20110038910A1 (en) | 2009-08-11 | 2011-02-17 | Atrium Medical Corporation | Anti-infective antimicrobial-containing biomaterials |
EP2359876A1 (en) * | 2010-02-12 | 2011-08-24 | Aesculap AG | Medical device comprising a porous article of ePTFE exhibiting improved cellular tissue ingrowth |
EP2593141B1 (en) | 2010-07-16 | 2018-07-04 | Atrium Medical Corporation | Composition and methods for altering the rate of hydrolysis of cured oil-based materials |
DE102011079680A1 (de) | 2011-07-22 | 2013-01-24 | Aesculap Ag | Beschichtetes Implantat und Verfahren zu seiner Herstellung |
US9867880B2 (en) | 2012-06-13 | 2018-01-16 | Atrium Medical Corporation | Cured oil-hydrogel biomaterial compositions for controlled drug delivery |
CN103816569B (zh) * | 2014-02-28 | 2016-05-11 | 丹阳纳瑞康纳米科技有限公司 | 一种气相Ag纳米颗粒处理的植入体医用材料的方法 |
DE102019108327A1 (de) * | 2019-03-29 | 2020-10-01 | Karl Leibinger Medizintechnik Gmbh & Co. Kg | Implantat mit intrinsischer antimikrobieller Wirksamkeit und Verfahren zu dessen Herstellung |
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US5019096A (en) * | 1988-02-11 | 1991-05-28 | Trustees Of Columbia University In The City Of New York | Infection-resistant compositions, medical devices and surfaces and methods for preparing and using same |
US5464438A (en) * | 1988-10-05 | 1995-11-07 | Menaker; Gerald J. | Gold coating means for limiting thromboses in implantable grafts |
US5320908A (en) * | 1989-05-04 | 1994-06-14 | Ad Tech Holdings Limited | Deposition of an extremely thin silver layer on a nonconducting substrate |
US5647858A (en) * | 1989-07-25 | 1997-07-15 | Smith & Nephew, Inc. | Zirconium oxide and zirconium nitride coated catheters |
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CA2178541C (en) * | 1995-06-07 | 2009-11-24 | Neal E. Fearnot | Implantable medical device |
US6530951B1 (en) * | 1996-10-24 | 2003-03-11 | Cook Incorporated | Silver implantable medical device |
DE19718430A1 (de) * | 1997-04-30 | 1999-01-14 | Stemberger Axel Dr | Behandlung von Biomaterial |
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US6585767B1 (en) * | 1998-11-23 | 2003-07-01 | Agion Technologies, Inc. | Antimicrobial suturing ring for heart valve |
AU3724900A (en) * | 1999-03-05 | 2000-09-21 | Louis R. Matson | Surface-modified bioactive surgical implants suppressing tissue growth |
ATE283514T1 (de) * | 1999-06-30 | 2004-12-15 | Science Corp Comp | Verfahren und vorrichtung zum untersuchen von transaktionsaufzeichnungen in einem rechnersystem |
US7179849B2 (en) * | 1999-12-15 | 2007-02-20 | C. R. Bard, Inc. | Antimicrobial compositions containing colloids of oligodynamic metals |
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KR100356643B1 (ko) * | 2000-03-31 | 2002-10-18 | 한국과학기술연구원 | 생리활성 물질이 결합된 생체적합성 의료용 금속 재료 및이의 제조 방법 |
DE20020649U1 (de) * | 2000-12-06 | 2002-04-11 | Stryker Trauma Gmbh | Vorrichtung für den chirurgischen oder therapeutischen Gebrauch, insbesondere Implantate und chirurgische Instrumente sowie deren Zubehör |
DE10107675B4 (de) * | 2001-02-19 | 2004-11-25 | Implantcast Gmbh | Endoprothese und Verfahren zu ihrer Herstellung |
MXPA04005332A (es) * | 2001-12-03 | 2005-05-16 | Bard Inc C R | Dispositivo medico resistente a microbios, revestimiento polimerico resistente a microbios y metodos para producir los mismos. |
-
2003
- 2003-05-15 DE DE10323676A patent/DE10323676A1/de not_active Withdrawn
-
2004
- 2004-05-14 EP EP04732956A patent/EP1513563B1/de not_active Expired - Lifetime
- 2004-05-14 WO PCT/EP2004/005162 patent/WO2004101010A1/de active IP Right Grant
- 2004-05-14 PL PL04732956T patent/PL1513563T3/pl unknown
- 2004-05-14 US US10/521,455 patent/US20060051544A1/en not_active Abandoned
- 2004-05-14 ES ES04732956T patent/ES2252729T3/es not_active Expired - Lifetime
- 2004-05-14 JP JP2006529811A patent/JP2006528893A/ja active Pending
- 2004-05-14 DE DE502004000107T patent/DE502004000107D1/de not_active Expired - Lifetime
- 2004-05-14 AT AT04732956T patent/ATE306950T1/de not_active IP Right Cessation
-
2005
- 2005-12-08 NO NO20055834A patent/NO330697B1/no not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO2004101010A1 (de) | 2004-11-25 |
NO20055834D0 (no) | 2005-12-08 |
US20060051544A1 (en) | 2006-03-09 |
PL1513563T3 (pl) | 2006-03-31 |
JP2006528893A (ja) | 2006-12-28 |
EP1513563B1 (de) | 2005-10-19 |
ATE306950T1 (de) | 2005-11-15 |
EP1513563A1 (de) | 2005-03-16 |
NO20055834L (no) | 2005-12-08 |
DE10323676A1 (de) | 2004-12-02 |
ES2252729T3 (es) | 2006-05-16 |
DE502004000107D1 (de) | 2006-03-02 |
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