NO329743B1 - Imidazokinolinderivater, fremgangsmate for fremstilling derav, mellomprodukter i fremgangsmaten for fremstilling av forbindelsene, farmasoytiske preparater inneholdende forbindelsene og anvendelse av forbindelsene til fremstilling av farmasoytiske preparater - Google Patents
Imidazokinolinderivater, fremgangsmate for fremstilling derav, mellomprodukter i fremgangsmaten for fremstilling av forbindelsene, farmasoytiske preparater inneholdende forbindelsene og anvendelse av forbindelsene til fremstilling av farmasoytiske preparater Download PDFInfo
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- NO329743B1 NO329743B1 NO20043117A NO20043117A NO329743B1 NO 329743 B1 NO329743 B1 NO 329743B1 NO 20043117 A NO20043117 A NO 20043117A NO 20043117 A NO20043117 A NO 20043117A NO 329743 B1 NO329743 B1 NO 329743B1
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- 150000008044 alkali metal hydroxides Chemical class 0.000 description 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 1
- 230000003042 antagnostic effect Effects 0.000 description 1
- ZSIQJIWKELUFRJ-UHFFFAOYSA-N azepane Chemical group C1CCCNCC1 ZSIQJIWKELUFRJ-UHFFFAOYSA-N 0.000 description 1
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- 230000009286 beneficial effect Effects 0.000 description 1
- PXXJHWLDUBFPOL-UHFFFAOYSA-N benzamidine Chemical compound NC(=N)C1=CC=CC=C1 PXXJHWLDUBFPOL-UHFFFAOYSA-N 0.000 description 1
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 230000002057 chronotropic effect Effects 0.000 description 1
- 235000015165 citric acid Nutrition 0.000 description 1
- 239000002299 complementary DNA Substances 0.000 description 1
- 125000000753 cycloalkyl group Chemical group 0.000 description 1
- 125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 description 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 description 1
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- IQDGSYLLQPDQDV-UHFFFAOYSA-N dimethylazanium;chloride Chemical compound Cl.CNC IQDGSYLLQPDQDV-UHFFFAOYSA-N 0.000 description 1
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- XWBDWHCCBGMXKG-UHFFFAOYSA-N ethanamine;hydron;chloride Chemical compound Cl.CCN XWBDWHCCBGMXKG-UHFFFAOYSA-N 0.000 description 1
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- 230000004217 heart function Effects 0.000 description 1
- 125000000623 heterocyclic group Chemical group 0.000 description 1
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- 239000008188 pellet Substances 0.000 description 1
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- 125000003395 phenylethylamino group Chemical group [H]N(*)C([H])([H])C([H])([H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 description 1
- 238000011321 prophylaxis Methods 0.000 description 1
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- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- HDOUGSFASVGDCS-UHFFFAOYSA-N pyridin-3-ylmethanamine Chemical compound NCC1=CC=CN=C1 HDOUGSFASVGDCS-UHFFFAOYSA-N 0.000 description 1
- TXQWFIVRZNOPCK-UHFFFAOYSA-N pyridin-4-ylmethanamine Chemical compound NCC1=CC=NC=C1 TXQWFIVRZNOPCK-UHFFFAOYSA-N 0.000 description 1
- LOAUVZALPPNFOQ-UHFFFAOYSA-M quinaldate Chemical compound C1=CC=CC2=NC(C(=O)[O-])=CC=C21 LOAUVZALPPNFOQ-UHFFFAOYSA-M 0.000 description 1
- ZEXKKIXCRDTKBF-UHFFFAOYSA-N quinoline-2-carboxamide Chemical compound C1=CC=CC2=NC(C(=O)N)=CC=C21 ZEXKKIXCRDTKBF-UHFFFAOYSA-N 0.000 description 1
- XEORENVXIPLVSZ-UHFFFAOYSA-N quinoline-2-carboxylic acid hydrate Chemical compound O.N1=C(C=CC2=CC=CC=C12)C(=O)O XEORENVXIPLVSZ-UHFFFAOYSA-N 0.000 description 1
- 239000002287 radioligand Substances 0.000 description 1
- 238000001953 recrystallisation Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000009711 regulatory function Effects 0.000 description 1
- 210000002345 respiratory system Anatomy 0.000 description 1
- 238000013391 scatchard analysis Methods 0.000 description 1
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- 231100001274 therapeutic index Toxicity 0.000 description 1
- 150000008634 thiazolopyrimidines Chemical class 0.000 description 1
- GLQWRXYOTXRDNH-UHFFFAOYSA-N thiophen-2-amine Chemical compound NC1=CC=CS1 GLQWRXYOTXRDNH-UHFFFAOYSA-N 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
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- 231100000048 toxicity data Toxicity 0.000 description 1
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Classifications
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Ophthalmology & Optometry (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Rheumatology (AREA)
- Psychiatry (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU0105406A HUP0105406A3 (en) | 2001-12-21 | 2001-12-21 | Imidazo[1,2-a]quinolin derivatives, process for their preparation, pharmaceutical compositions thereof and intermediates |
| PCT/HU2002/000144 WO2003053969A1 (en) | 2001-12-21 | 2002-12-17 | Imidazoquinoline derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20043117L NO20043117L (no) | 2004-07-20 |
| NO329743B1 true NO329743B1 (no) | 2010-12-13 |
Family
ID=47711504
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20043117A NO329743B1 (no) | 2001-12-21 | 2004-07-20 | Imidazokinolinderivater, fremgangsmate for fremstilling derav, mellomprodukter i fremgangsmaten for fremstilling av forbindelsene, farmasoytiske preparater inneholdende forbindelsene og anvendelse av forbindelsene til fremstilling av farmasoytiske preparater |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US7176213B2 (xx) |
| EP (1) | EP1456205A1 (xx) |
| JP (1) | JP4530663B2 (xx) |
| KR (2) | KR20070034136A (xx) |
| CN (1) | CN1307174C (xx) |
| AU (1) | AU2002353241B2 (xx) |
| BR (1) | BR0215272A (xx) |
| CA (1) | CA2470067C (xx) |
| EA (1) | EA007226B1 (xx) |
| HR (1) | HRP20040671A2 (xx) |
| HU (1) | HUP0105406A3 (xx) |
| IL (2) | IL162443A0 (xx) |
| IS (1) | IS7317A (xx) |
| MA (1) | MA27240A1 (xx) |
| MX (1) | MXPA04006115A (xx) |
| NO (1) | NO329743B1 (xx) |
| NZ (1) | NZ534015A (xx) |
| PL (1) | PL370761A1 (xx) |
| RS (1) | RS56104A (xx) |
| TN (1) | TNSN04105A1 (xx) |
| UA (1) | UA78745C2 (xx) |
| WO (1) | WO2003053969A1 (xx) |
| ZA (1) | ZA200404807B (xx) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003027068A2 (en) * | 2001-09-24 | 2003-04-03 | Elan Pharmaceuticals, Inc. | Substituted amines for the treatment of neurological disorders |
| HUP0203976A3 (en) * | 2002-11-15 | 2004-08-30 | Sanofi Aventis | Adenozine a3 receptors, process for their preparation and pharmaceutical compositions containing them |
| HUP0400812A2 (en) * | 2004-04-19 | 2006-02-28 | Sanofi Aventis | Crystalline forms of 2-amino-3-cyano-quinoline derivatives, process for their preparation and pharmaceutical compositions containing them |
| AU2006216822A1 (en) * | 2005-02-22 | 2006-08-31 | Daniel Rachmilewitz | Methods of treating gastrointestinal inflammation |
| HUP0700395A2 (en) * | 2007-06-07 | 2009-03-02 | Sanofi Aventis | Substituted [1,2,4] triazolo [1,5-a] quinolines, process for their preparation, pharmaceutical compositions thereof, and intermediates |
| US8357132B1 (en) | 2009-10-21 | 2013-01-22 | Lekweuwa Agatha N | Urine capturing assembly |
| CA3217159A1 (en) | 2013-02-01 | 2014-08-07 | Wellstat Therapeutics Corporation | Substituted quinazolin-4-amine compounds and pharmaceutical compositions thereof having anti-inflammatory, antifungal, antiparasitic and anticancer activity |
| ES2578363B1 (es) | 2015-01-22 | 2017-01-31 | Palobiofarma, S.L. | Moduladores de los receptores A3 de adenosina |
| JP6955482B2 (ja) | 2015-08-03 | 2021-10-27 | ブリストル−マイヤーズ スクイブ カンパニーＢｒｉｓｔｏｌ−Ｍｙｅｒｓ Ｓｑｕｉｂｂ Ｃｏｍｐａｎｙ | Ｔｎｆアルファの修飾因子として有用なヘテロ環化合物 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4075343A (en) * | 1976-09-13 | 1978-02-21 | Pfizer Inc. | Anti-allergenic 5-alkoxyimidazo[1,2-A]quinoline-2-carboxylic acids and derivatives thereof |
| GB1596652A (en) | 1977-01-20 | 1981-08-26 | Roussel Lab Ltd | Imidazo (1,2-a) quinoline-2-carboxylic acid and derivatives |
| IL59104A (en) | 1979-02-09 | 1984-02-29 | Roussel Uclaf | Heterotricyclic derivatives,process for their preparation and pharmaceutical compositions incorporating them |
| GR76063B (xx) | 1981-04-03 | 1984-08-03 | Roussel Uclaf | |
| HUP0203976A3 (en) * | 2002-11-15 | 2004-08-30 | Sanofi Aventis | Adenozine a3 receptors, process for their preparation and pharmaceutical compositions containing them |
-
2001
- 2001-12-21 HU HU0105406A patent/HUP0105406A3/hu unknown
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2002
- 2002-12-17 RS YU56104A patent/RS56104A/sr unknown
- 2002-12-17 AU AU2002353241A patent/AU2002353241B2/en not_active Ceased
- 2002-12-17 PL PL02370761A patent/PL370761A1/xx not_active Application Discontinuation
- 2002-12-17 WO PCT/HU2002/000144 patent/WO2003053969A1/en active Application Filing
- 2002-12-17 EP EP02788261A patent/EP1456205A1/en not_active Withdrawn
- 2002-12-17 BR BR0215272-0A patent/BR0215272A/pt not_active IP Right Cessation
- 2002-12-17 IL IL16244302A patent/IL162443A0/xx unknown
- 2002-12-17 JP JP2003554685A patent/JP4530663B2/ja not_active Expired - Fee Related
- 2002-12-17 NZ NZ534015A patent/NZ534015A/en not_active IP Right Cessation
- 2002-12-17 KR KR1020077004953A patent/KR20070034136A/ko not_active Application Discontinuation
- 2002-12-17 CN CNB02825645XA patent/CN1307174C/zh not_active Expired - Fee Related
- 2002-12-17 UA UA20040706065A patent/UA78745C2/uk unknown
- 2002-12-17 CA CA2470067A patent/CA2470067C/en not_active Expired - Fee Related
- 2002-12-17 US US10/499,251 patent/US7176213B2/en not_active Expired - Fee Related
- 2002-12-17 EA EA200400847A patent/EA007226B1/ru not_active IP Right Cessation
- 2002-12-17 KR KR1020047009788A patent/KR100725298B1/ko not_active IP Right Cessation
- 2002-12-17 MX MXPA04006115A patent/MXPA04006115A/es active IP Right Grant
-
2004
- 2004-06-07 MA MA27725A patent/MA27240A1/fr unknown
- 2004-06-08 TN TNP2004000105A patent/TNSN04105A1/en unknown
- 2004-06-10 IL IL162443A patent/IL162443A/en not_active IP Right Cessation
- 2004-06-16 IS IS7317A patent/IS7317A/is unknown
- 2004-06-17 ZA ZA200404807A patent/ZA200404807B/xx unknown
- 2004-07-20 NO NO20043117A patent/NO329743B1/no not_active IP Right Cessation
- 2004-07-20 HR HR20040671A patent/HRP20040671A2/xx not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| US7176213B2 (en) | 2007-02-13 |
| MXPA04006115A (es) | 2005-06-08 |
| MA27240A1 (fr) | 2005-03-01 |
| CN1307174C (zh) | 2007-03-28 |
| EA007226B1 (ru) | 2006-08-25 |
| EP1456205A1 (en) | 2004-09-15 |
| IL162443A (en) | 2010-05-17 |
| JP2005516956A (ja) | 2005-06-09 |
| HRP20040671A2 (en) | 2005-08-31 |
| PL370761A1 (en) | 2005-05-30 |
| AU2002353241A1 (en) | 2003-07-09 |
| RS56104A (xx) | 2006-10-27 |
| US20050070566A1 (en) | 2005-03-31 |
| CA2470067C (en) | 2011-02-15 |
| IL162443A0 (en) | 2005-11-20 |
| CN1606555A (zh) | 2005-04-13 |
| AU2002353241B2 (en) | 2008-07-10 |
| IS7317A (is) | 2004-06-16 |
| BR0215272A (pt) | 2004-12-14 |
| HUP0105406A3 (en) | 2003-12-29 |
| ZA200404807B (en) | 2005-08-29 |
| NO20043117L (no) | 2004-07-20 |
| KR100725298B1 (ko) | 2007-06-07 |
| HUP0105406D0 (en) | 2002-03-28 |
| WO2003053969A1 (en) | 2003-07-03 |
| NZ534015A (en) | 2005-04-29 |
| CA2470067A1 (en) | 2003-07-03 |
| KR20070034136A (ko) | 2007-03-27 |
| UA78745C2 (en) | 2007-04-25 |
| HUP0105406A2 (hu) | 2003-10-28 |
| JP4530663B2 (ja) | 2010-08-25 |
| EA200400847A1 (ru) | 2004-12-30 |
| TNSN04105A1 (en) | 2006-06-01 |
| KR20040072670A (ko) | 2004-08-18 |
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| MM1K | Lapsed by not paying the annual fees |