NO329320B1 - Formulering for behandling av hjerne-, spinal- og nerveskade. - Google Patents
Formulering for behandling av hjerne-, spinal- og nerveskade. Download PDFInfo
- Publication number
- NO329320B1 NO329320B1 NO20023423A NO20023423A NO329320B1 NO 329320 B1 NO329320 B1 NO 329320B1 NO 20023423 A NO20023423 A NO 20023423A NO 20023423 A NO20023423 A NO 20023423A NO 329320 B1 NO329320 B1 NO 329320B1
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- Prior art keywords
- brain
- magnesium
- substance
- injury
- damage
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPQ5146A AUPQ514600A0 (en) | 2000-01-18 | 2000-01-18 | Brain injury treatment |
| PCT/AU2001/000046 WO2001052844A1 (en) | 2000-01-18 | 2001-01-18 | Brain, spinal and nerve injury treatment |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20023423D0 NO20023423D0 (no) | 2002-07-17 |
| NO20023423L NO20023423L (no) | 2002-09-16 |
| NO329320B1 true NO329320B1 (no) | 2010-09-27 |
Family
ID=3819274
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20023423A NO329320B1 (no) | 2000-01-18 | 2002-07-17 | Formulering for behandling av hjerne-, spinal- og nerveskade. |
Country Status (20)
| Country | Link |
|---|---|
| US (5) | US6841551B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP1261335B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP4794794B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR100780119B1 (cg-RX-API-DMAC7.html) |
| CN (1) | CN1261095C (cg-RX-API-DMAC7.html) |
| AU (2) | AUPQ514600A0 (cg-RX-API-DMAC7.html) |
| BR (1) | BR0107695A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2397723C (cg-RX-API-DMAC7.html) |
| CZ (1) | CZ20022804A3 (cg-RX-API-DMAC7.html) |
| DE (1) | DE60139244D1 (cg-RX-API-DMAC7.html) |
| HR (1) | HRP20020593B1 (cg-RX-API-DMAC7.html) |
| HU (1) | HUP0301920A3 (cg-RX-API-DMAC7.html) |
| IL (2) | IL150548A0 (cg-RX-API-DMAC7.html) |
| MX (1) | MXPA02007004A (cg-RX-API-DMAC7.html) |
| NO (1) | NO329320B1 (cg-RX-API-DMAC7.html) |
| NZ (2) | NZ519990A (cg-RX-API-DMAC7.html) |
| RU (1) | RU2276996C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2001052844A1 (cg-RX-API-DMAC7.html) |
| YU (1) | YU54702A (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200205715B (cg-RX-API-DMAC7.html) |
Families Citing this family (52)
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|---|---|---|---|---|
| AUPQ514600A0 (en) | 2000-01-18 | 2000-02-10 | James Cook University | Brain injury treatment |
| US20030083345A1 (en) * | 2001-07-10 | 2003-05-01 | Torsten Hoffmann | Method of treatment and/or prevention of brain, spinal or nerve injury |
| DE602004028678D1 (de) | 2003-01-28 | 2010-09-23 | Ironwood Pharmaceuticals Inc | Zusammensetzungen zur Behandlung von Magen-Darm-Störungen |
| US7772188B2 (en) | 2003-01-28 | 2010-08-10 | Ironwood Pharmaceuticals, Inc. | Methods and compositions for the treatment of gastrointestinal disorders |
| GB0410215D0 (en) * | 2004-05-07 | 2004-06-09 | Lescroart Pol | Nerve damage |
| US20080045610A1 (en) * | 2004-09-23 | 2008-02-21 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| AU2005286733B2 (en) * | 2004-09-23 | 2009-11-05 | Alexander Michalow | Methods for regulating neurotransmitter systems by inducing counteradaptations |
| EP1855655A2 (en) | 2005-02-25 | 2007-11-21 | F. Hoffmann-Roche AG | Tablets with improved drug substance dispersibility |
| WO2006110118A1 (fr) * | 2005-04-15 | 2006-10-19 | Victor Pavlovich Kutnyak | Produit cytoprotecteur |
| US20060239921A1 (en) | 2005-04-26 | 2006-10-26 | Novadaq Technologies Inc. | Real time vascular imaging during solid organ transplant |
| US8185176B2 (en) | 2005-04-26 | 2012-05-22 | Novadaq Technologies, Inc. | Method and apparatus for vasculature visualization with applications in neurosurgery and neurology |
| WO2007016790A1 (en) * | 2005-08-10 | 2007-02-15 | Novadaq Technologies, Inc. | Intra-operative head & neck nerve mapping |
| US20070122344A1 (en) * | 2005-09-02 | 2007-05-31 | University Of Rochester Medical Center Office Of Technology Transfer | Intraoperative determination of nerve location |
| WO2007062060A2 (en) * | 2005-11-22 | 2007-05-31 | Ted Reid | Methods and compositions using substance p to promote wound healing |
| US8945623B2 (en) * | 2006-05-03 | 2015-02-03 | Warsaw Orthopedic, Inc. | Compositions comprising biomembrane sealing agent for treatment of neuronal injury, and methods of use |
| US20080161744A1 (en) * | 2006-09-07 | 2008-07-03 | University Of Rochester Medical Center | Pre-And Intra-Operative Localization of Penile Sentinel Nodes |
| US20100086543A1 (en) * | 2007-04-02 | 2010-04-08 | Saint Louis University | Compositions and methods for treating conditions associated with ceramide biosynthesis |
| US20080241121A1 (en) * | 2007-04-02 | 2008-10-02 | Daniela Salvemini | Inhibitors of the ceramide metabolic pathway as adjuncts to opiates for pain |
| MX354786B (es) | 2007-06-04 | 2018-03-21 | Synergy Pharmaceuticals Inc | Agonistas de guanilato ciclasa utiles para el tratamiento de trastornos gastrointestinales, inflamacion, cancer y otros trastornos. |
| US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
| CA2700477A1 (en) * | 2007-07-19 | 2009-01-22 | Adelaide Research & Innovation Pty Ltd | Method for reducing intracranial pressure |
| US8406860B2 (en) | 2008-01-25 | 2013-03-26 | Novadaq Technologies Inc. | Method for evaluating blush in myocardial tissue |
| US10219742B2 (en) | 2008-04-14 | 2019-03-05 | Novadaq Technologies ULC | Locating and analyzing perforator flaps for plastic and reconstructive surgery |
| US20090263507A1 (en) * | 2008-04-18 | 2009-10-22 | Warsaw Orthopedic, Inc. | Biological markers and response to treatment for pain, inflammation, neuronal or vascular injury and methods of use |
| EP2285421B1 (en) | 2008-05-02 | 2018-04-11 | Novadaq Technologies ULC | Methods for production and use of substance-loaded erythrocytes for observation and treatment of microvascular hemodynamics |
| CA2930674A1 (en) | 2008-06-04 | 2009-12-10 | Synergy Pharmaceuticals Inc. | Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders |
| JP2011528375A (ja) | 2008-07-16 | 2011-11-17 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
| WO2018129556A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| KR20220042487A (ko) | 2008-12-31 | 2022-04-05 | 알데릭스, 인코포레이티드 | 체액 저류 또는 염 과부하와 연관된 장애 및 위장관 장애의 치료 시에 ｎｈｅ-매개된 역수송을 억제하는 화합물 및 방법 |
| US8852566B2 (en) * | 2009-03-26 | 2014-10-07 | Warsaw Orthopedic, Inc. | Compositions and methods for preferential distribution of active agents to injury sites |
| US10492671B2 (en) | 2009-05-08 | 2019-12-03 | Novadaq Technologies ULC | Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest |
| US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
| WO2012074043A1 (ja) * | 2010-12-03 | 2012-06-07 | 国立大学法人 岡山大学 | 外傷性神経障害治療剤 |
| WO2012125020A1 (en) * | 2011-03-14 | 2012-09-20 | N.V. Nutricia | Method for treating neurotrauma |
| JP6028096B2 (ja) | 2012-06-21 | 2016-11-16 | ノバダック テクノロジーズ インコーポレイテッド | 血管造影及びかん流の定量化並びに解析手法 |
| US10376481B2 (en) | 2012-08-21 | 2019-08-13 | Ardelyx, Inc. | Compounds and methods for inhibiting NHE-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders |
| JP6392754B2 (ja) | 2012-08-21 | 2018-09-19 | アーデリクス，インコーポレーテッド | 体液貯留又は塩過負荷に関係する疾患及び消化管疾患の治療におけるｎｈｅ仲介の逆輸送を阻害するための化合物並びに方法 |
| US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
| CA2905435A1 (en) | 2013-03-15 | 2014-09-25 | Synergy Pharmaceuticals Inc. | Compositions useful for the treatment of gastrointestinal disorders |
| BR112015025805A2 (pt) | 2013-04-12 | 2017-07-25 | Ardelyx Inc | compostos de ligação de nh3 e métodos para inibir o transporte de fosfato |
| EP4424697A3 (en) | 2013-06-05 | 2024-12-25 | Bausch Health Ireland Limited | Ultra-pure agonists of guanylate cyclase c, method of making and using same |
| WO2015000034A1 (en) * | 2013-07-02 | 2015-01-08 | Eustralis Pharmaceuticals Limited (Trading As Pressura Neuro) | Method for preventing and/or treating chronic traumatic encephalopathy-iii |
| EP3016642B1 (en) * | 2013-07-02 | 2019-03-13 | Eustralis Pharmaceuticals Limited (Trading as Pressura Neuro) | Method for preventing and/or treating chronic traumatic encephalopathy-i |
| US20160129007A1 (en) * | 2013-07-02 | 2016-05-12 | Eustralis Pharmaceuticals Limited (Trading As Pressura Neuro) | Method for Preventing and/or Treating Chronic Traumatic Encephalopathy - IV |
| NZ714708A (en) * | 2013-07-02 | 2019-06-28 | Eustralis Pharmaceuticals Ltd Trading As Pressura Neuro | Method for preventing and/or treating chronic traumatic encephalopathy-ii |
| CN107209118B (zh) | 2014-09-29 | 2021-05-28 | 史赛克欧洲运营有限公司 | 在自体荧光存在下生物材料中目标荧光团的成像 |
| KR101955134B1 (ko) | 2014-10-09 | 2019-03-06 | 노바다크 테크놀러지즈 유엘씨 | 형광-조정 광전용적맥파 측정기를 사용한 조직 내의 절대적인 혈류의 정량화 |
| BR112019013963A2 (pt) | 2017-01-09 | 2020-04-28 | Ardelyx Inc | inibidores de antiporte mediado por nhe |
| WO2018129552A1 (en) | 2017-01-09 | 2018-07-12 | Ardelyx, Inc. | Compounds useful for treating gastrointestinal tract disorders |
| WO2018145193A1 (en) | 2017-02-10 | 2018-08-16 | Novadaq Technologies ULC | Open-field handheld fluorescence imaging systems and methods |
| WO2021035289A1 (en) * | 2019-08-23 | 2021-03-04 | Eustralis Pharmaceuticals Limited (Trading As Pressura Neuro) | Therapeutic methods and uses thereof |
| WO2021202286A1 (en) * | 2020-03-30 | 2021-10-07 | Dignify Therapeutics, Llc | Compositions and methods for treating autonomic dysreflexia |
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| US4481139A (en) * | 1983-04-13 | 1984-11-06 | Board Of Regents, The University Of Texas System | Peptide antagonists of substance P |
| US4985896A (en) * | 1985-03-29 | 1991-01-15 | Canon Kabushiki Kaisha | Laser driving device |
| GB8929070D0 (en) * | 1989-12-22 | 1990-02-28 | Fujisawa Pharmaceutical Co | Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same |
| US4981744A (en) * | 1990-04-24 | 1991-01-01 | Swank Michael W | Non-planar expandable honeycomb structure |
| JP3507494B2 (ja) * | 1992-08-13 | 2004-03-15 | ワーナー−ランバート・コンパニー | タキキニン拮抗薬 |
| US5610165A (en) | 1994-02-17 | 1997-03-11 | Merck & Co., Inc. | N-acylpiperidine tachykinin antagonists |
| US5744482A (en) * | 1994-10-05 | 1998-04-28 | Eli Lilly And Company | Serotonin agonist in combination with a tachykinin receptor antagonist in the treatment or prevention of migraine |
| US5998444A (en) * | 1995-10-24 | 1999-12-07 | Zeneca Ltd. | Piperidinyl compounds as NK1 or NK2 antagonists |
| IL116249A (en) * | 1994-12-12 | 2003-07-06 | Pfizer | Nk-1 receptor antagonists for the treatment of neuronal damage and stroke |
| AU4918796A (en) * | 1995-02-10 | 1996-08-27 | Eli Lilly And Company | Methods of treating or preventing psychiatric disorders |
| US5795894A (en) * | 1995-05-02 | 1998-08-18 | Schering Corporation | Piperazino derivatives as neurokinn antagonists |
| US5990125A (en) | 1996-01-19 | 1999-11-23 | Pfizer Inc. | NK-1 receptor antagonists for the treatment of cancer |
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| US5977104A (en) * | 1996-12-02 | 1999-11-02 | Merck Sharp & Dohme Ltd. | Use of NK-1 receptor antagonists for treating bipolar disorders |
| AU749976B2 (en) * | 1997-08-28 | 2002-07-04 | Merck & Co., Inc. | Method for treating premenstrual or late luteal phase syndrome |
| GB9812662D0 (en) * | 1998-06-11 | 1998-08-12 | Merck Sharp & Dohme | Therapeutic use |
| CN1131212C (zh) | 1999-02-24 | 2003-12-17 | 弗·哈夫曼-拉罗切有限公司 | 苯基－和吡啶基衍生物 |
| HRP20010604A2 (en) | 1999-02-24 | 2002-08-31 | Hoffmann La Roche | 3-phenylpyridine derivatives and their use as nk-1 receptor antagonists |
| SI1035115T1 (en) * | 1999-02-24 | 2005-02-28 | F. Hoffmann-La Roche Ag | 4-Phenylpyridine derivatives and their use as NK-1 receptor antagonists |
| US6291465B1 (en) | 1999-03-09 | 2001-09-18 | Hoffmann-La Roche Inc. | Biphenyl derivatives |
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| US6274588B1 (en) | 1999-05-31 | 2001-08-14 | Hoffmann-La Roche Inc. | 4-phenyl-pyrimidine derivatives |
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| AUPQ514600A0 (en) | 2000-01-18 | 2000-02-10 | James Cook University | Brain injury treatment |
| US6479433B1 (en) * | 2000-10-02 | 2002-11-12 | Smithers-Oasis Company | Polyurethane foam composites for grower applications and related methods |
-
2000
- 2000-01-18 AU AUPQ5146A patent/AUPQ514600A0/en not_active Abandoned
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2001
- 2001-01-18 US US10/181,323 patent/US6841551B2/en not_active Expired - Fee Related
- 2001-01-18 EP EP01901048A patent/EP1261335B1/en not_active Expired - Lifetime
- 2001-01-18 DE DE60139244T patent/DE60139244D1/de not_active Expired - Fee Related
- 2001-01-18 RU RU2002121640/15A patent/RU2276996C2/ru not_active IP Right Cessation
- 2001-01-18 CZ CZ20022804A patent/CZ20022804A3/cs unknown
- 2001-01-18 BR BR0107695-7A patent/BR0107695A/pt not_active IP Right Cessation
- 2001-01-18 CN CNB018037208A patent/CN1261095C/zh not_active Expired - Fee Related
- 2001-01-18 HU HU0301920A patent/HUP0301920A3/hu unknown
- 2001-01-18 YU YU54702A patent/YU54702A/sh unknown
- 2001-01-18 HR HR20020593A patent/HRP20020593B1/xx not_active IP Right Cessation
- 2001-01-18 NZ NZ519990A patent/NZ519990A/en not_active IP Right Cessation
- 2001-01-18 WO PCT/AU2001/000046 patent/WO2001052844A1/en not_active Ceased
- 2001-01-18 IL IL15054801A patent/IL150548A0/xx unknown
- 2001-01-18 MX MXPA02007004A patent/MXPA02007004A/es active IP Right Grant
- 2001-01-18 CA CA2397723A patent/CA2397723C/en not_active Expired - Fee Related
- 2001-01-18 KR KR1020027009218A patent/KR100780119B1/ko not_active Expired - Fee Related
- 2001-01-18 NZ NZ534278A patent/NZ534278A/en not_active IP Right Cessation
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2002
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- 2002-07-17 ZA ZA200205715A patent/ZA200205715B/en unknown
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2004
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2009
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2015
- 2015-10-13 US US14/882,084 patent/US20160030474A1/en not_active Abandoned
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2017
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