NO327910B1 - Taxaner, farmasoytiske preparater som omfatter disse, preparater for oral administrering som omfatter taxanene, samt anvendelse av taxanene til fremstilling av orale farmasoytiske preparater for inhibering av tumorvekst hos pattedyr - Google Patents

Taxaner, farmasoytiske preparater som omfatter disse, preparater for oral administrering som omfatter taxanene, samt anvendelse av taxanene til fremstilling av orale farmasoytiske preparater for inhibering av tumorvekst hos pattedyr Download PDF

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Publication number
NO327910B1
NO327910B1 NO20014754A NO20014754A NO327910B1 NO 327910 B1 NO327910 B1 NO 327910B1 NO 20014754 A NO20014754 A NO 20014754A NO 20014754 A NO20014754 A NO 20014754A NO 327910 B1 NO327910 B1 NO 327910B1
Authority
NO
Norway
Prior art keywords
furyl
thienyl
ethyl
taxane
propyl
Prior art date
Application number
NO20014754A
Other languages
English (en)
Norwegian (no)
Other versions
NO20014754D0 (no
NO20014754L (no
Inventor
Robert A Holton
Original Assignee
Univ Florida State Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida State Res Found filed Critical Univ Florida State Res Found
Publication of NO20014754D0 publication Critical patent/NO20014754D0/no
Publication of NO20014754L publication Critical patent/NO20014754L/no
Publication of NO327910B1 publication Critical patent/NO327910B1/no

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/75—Aerosol containers not provided for in groups B65D83/16 - B65D83/74
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20014754A 2000-02-02 2001-10-01 Taxaner, farmasoytiske preparater som omfatter disse, preparater for oral administrering som omfatter taxanene, samt anvendelse av taxanene til fremstilling av orale farmasoytiske preparater for inhibering av tumorvekst hos pattedyr NO327910B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17978200P 2000-02-02 2000-02-02
PCT/US2001/003623 WO2001057032A1 (en) 2000-02-02 2001-02-02 C10 ester substituted taxanes as antitumor agents

Publications (3)

Publication Number Publication Date
NO20014754D0 NO20014754D0 (no) 2001-10-01
NO20014754L NO20014754L (no) 2001-11-29
NO327910B1 true NO327910B1 (no) 2009-10-19

Family

ID=22657972

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20014754A NO327910B1 (no) 2000-02-02 2001-10-01 Taxaner, farmasoytiske preparater som omfatter disse, preparater for oral administrering som omfatter taxanene, samt anvendelse av taxanene til fremstilling av orale farmasoytiske preparater for inhibering av tumorvekst hos pattedyr

Country Status (25)

Country Link
EP (1) EP1165553B1 (enExample)
JP (1) JP2003522172A (enExample)
CN (1) CN1380882A (enExample)
AT (1) ATE432928T1 (enExample)
AU (1) AU782150B2 (enExample)
BG (1) BG64889B1 (enExample)
BR (1) BR0104354A (enExample)
CA (1) CA2368274C (enExample)
CZ (1) CZ20013430A3 (enExample)
DE (1) DE60138853D1 (enExample)
GE (1) GEP20043323B (enExample)
HU (1) HUP0600302A2 (enExample)
IL (1) IL145638A (enExample)
MX (1) MXPA01009905A (enExample)
NO (1) NO327910B1 (enExample)
NZ (1) NZ514382A (enExample)
PL (1) PL202957B1 (enExample)
RO (1) RO121270B1 (enExample)
RU (1) RU2262506C2 (enExample)
SK (1) SK13692001A3 (enExample)
TR (1) TR200102858T1 (enExample)
TW (1) TWI299732B (enExample)
UA (1) UA75039C2 (enExample)
WO (1) WO2001057032A1 (enExample)
ZA (1) ZA200108055B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
CA2354471A1 (en) * 2001-07-31 2003-01-31 Florida State University Research Foundation, Inc. C10 ester substituted taxanes
SG129990A1 (en) * 2001-08-01 2007-03-20 Univ Florida State Res Found C10 ester substituted taxanes
SV2006002010A (es) 2004-02-13 2006-08-23 Univ Florida State Res Found Taxanos sustituidos con esteres de ciclopentilo en c10
MX2007009748A (es) * 2005-02-14 2007-09-26 Univ Florida State Res Found Composiciones de taxano sustituidas con esteres ciclopropilicos en c10.
EP2276755A4 (en) * 2008-03-31 2011-05-04 Univ Florida State Res Found C (10) -ETHYESTER- AND C (10) -CYCLOPROPYLESTER-SUBSTITUTED TAXANES

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US5243045A (en) * 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
IL108443A0 (en) * 1993-01-29 1994-04-12 Univ Florida State C7 taxane derivatives and pharmaceutical compositions containing them
ATE209489T1 (de) * 1993-03-22 2001-12-15 Univ Florida State Taxane mit pyridyl-substituierter seitenkette
DK1227093T3 (da) * 1993-03-22 2005-08-29 Univ Florida State Beta-lactamer, der kan anvendes til fremstilling af taxaner med en furyl- eller thienylsubstitueret sidekæde
ATE195421T1 (de) * 1993-03-22 2000-09-15 Univ Florida State Taxane mit amino-substituierter seitenkette
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
WO1996013495A1 (en) * 1994-10-28 1996-05-09 The Research Foundation Of State University Of New York Taxoid derivatives, their preparation and their use as antitumor agents
US6100411A (en) * 1994-10-28 2000-08-08 The Research Foundation Of State University Of New York Taxoid anti-tumor agents and pharmaceutical compositions thereof
EP0914116B1 (en) * 1996-05-22 2000-10-11 Protarga Inc. Compositions comprising conjugates of cis-docosahexaenoic acid and taxotere
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
EP1044971A4 (en) * 1997-12-19 2001-11-07 Yakult Honsha Kk TAXAN DERIVATIVES
JP2003026673A (ja) * 1999-03-05 2003-01-29 Asahi Kasei Corp 骨形成促進剤

Also Published As

Publication number Publication date
DE60138853D1 (de) 2009-07-16
BG105965A (en) 2002-07-31
GEP20043323B (en) 2004-02-10
BR0104354A (pt) 2002-01-02
PL351380A1 (en) 2003-04-07
RO121270B1 (ro) 2007-02-28
NO20014754D0 (no) 2001-10-01
ATE432928T1 (de) 2009-06-15
CA2368274C (en) 2009-10-13
WO2001057032A1 (en) 2001-08-09
NO20014754L (no) 2001-11-29
UA75039C2 (en) 2006-03-15
SK13692001A3 (sk) 2002-07-02
CZ20013430A3 (cs) 2002-04-17
EP1165553A1 (en) 2002-01-02
PL202957B1 (pl) 2009-08-31
AU3480901A (en) 2001-08-14
CA2368274A1 (en) 2001-08-09
CN1380882A (zh) 2002-11-20
ZA200108055B (en) 2003-12-01
JP2003522172A (ja) 2003-07-22
BG64889B1 (bg) 2006-08-31
IL145638A0 (en) 2002-06-30
TR200102858T1 (tr) 2002-12-23
NZ514382A (en) 2004-05-28
MXPA01009905A (es) 2003-08-20
IL145638A (en) 2011-05-31
EP1165553B1 (en) 2009-06-03
TWI299732B (en) 2008-08-11
AU782150B2 (en) 2005-07-07
HUP0600302A2 (en) 2006-07-28
RU2262506C2 (ru) 2005-10-20

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