AU782150B2 - C10 ester substituted taxanes as antitumor agents - Google Patents

C10 ester substituted taxanes as antitumor agents Download PDF

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Publication number
AU782150B2
AU782150B2 AU34809/01A AU3480901A AU782150B2 AU 782150 B2 AU782150 B2 AU 782150B2 AU 34809/01 A AU34809/01 A AU 34809/01A AU 3480901 A AU3480901 A AU 3480901A AU 782150 B2 AU782150 B2 AU 782150B2
Authority
AU
Australia
Prior art keywords
taxane
furyl
thienyl
pyridyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU34809/01A
Other languages
English (en)
Other versions
AU3480901A (en
Inventor
Robert A. Holton
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Florida State University Research Foundation Inc
Original Assignee
Florida State University Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Florida State University Research Foundation Inc filed Critical Florida State University Research Foundation Inc
Publication of AU3480901A publication Critical patent/AU3480901A/en
Application granted granted Critical
Publication of AU782150B2 publication Critical patent/AU782150B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D83/00—Containers or packages with special means for dispensing contents
    • B65D83/14—Containers for dispensing liquid or semi-liquid contents by internal gaseous pressure, i.e. aerosol containers comprising propellant
    • B65D83/75—Aerosol containers not provided for in groups B65D83/16 - B65D83/74
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU34809/01A 2000-02-02 2001-02-02 C10 ester substituted taxanes as antitumor agents Ceased AU782150B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US17978200P 2000-02-02 2000-02-02
US60/179782 2000-02-02
PCT/US2001/003623 WO2001057032A1 (en) 2000-02-02 2001-02-02 C10 ester substituted taxanes as antitumor agents

Publications (2)

Publication Number Publication Date
AU3480901A AU3480901A (en) 2001-08-14
AU782150B2 true AU782150B2 (en) 2005-07-07

Family

ID=22657972

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34809/01A Ceased AU782150B2 (en) 2000-02-02 2001-02-02 C10 ester substituted taxanes as antitumor agents

Country Status (25)

Country Link
EP (1) EP1165553B1 (enExample)
JP (1) JP2003522172A (enExample)
CN (1) CN1380882A (enExample)
AT (1) ATE432928T1 (enExample)
AU (1) AU782150B2 (enExample)
BG (1) BG64889B1 (enExample)
BR (1) BR0104354A (enExample)
CA (1) CA2368274C (enExample)
CZ (1) CZ20013430A3 (enExample)
DE (1) DE60138853D1 (enExample)
GE (1) GEP20043323B (enExample)
HU (1) HUP0600302A2 (enExample)
IL (1) IL145638A (enExample)
MX (1) MXPA01009905A (enExample)
NO (1) NO327910B1 (enExample)
NZ (1) NZ514382A (enExample)
PL (1) PL202957B1 (enExample)
RO (1) RO121270B1 (enExample)
RU (1) RU2262506C2 (enExample)
SK (1) SK13692001A3 (enExample)
TR (1) TR200102858T1 (enExample)
TW (1) TWI299732B (enExample)
UA (1) UA75039C2 (enExample)
WO (1) WO2001057032A1 (enExample)
ZA (1) ZA200108055B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
CA2354471A1 (en) * 2001-07-31 2003-01-31 Florida State University Research Foundation, Inc. C10 ester substituted taxanes
SG129990A1 (en) * 2001-08-01 2007-03-20 Univ Florida State Res Found C10 ester substituted taxanes
SV2006002010A (es) 2004-02-13 2006-08-23 Univ Florida State Res Found Taxanos sustituidos con esteres de ciclopentilo en c10
MX2007009748A (es) * 2005-02-14 2007-09-26 Univ Florida State Res Found Composiciones de taxano sustituidas con esteres ciclopropilicos en c10.
EP2276755A4 (en) * 2008-03-31 2011-05-04 Univ Florida State Res Found C (10) -ETHYESTER- AND C (10) -CYCLOPROPYLESTER-SUBSTITUTED TAXANES

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6268381B1 (en) * 1997-12-19 2001-07-31 Kabushiki Kaisha Yakult Honsha Taxane derivatives

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
US5243045A (en) * 1991-09-23 1993-09-07 Florida State University Certain alkoxy substituted taxanes and pharmaceutical compositions containing them
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
IL108443A0 (en) * 1993-01-29 1994-04-12 Univ Florida State C7 taxane derivatives and pharmaceutical compositions containing them
ATE209489T1 (de) * 1993-03-22 2001-12-15 Univ Florida State Taxane mit pyridyl-substituierter seitenkette
DK1227093T3 (da) * 1993-03-22 2005-08-29 Univ Florida State Beta-lactamer, der kan anvendes til fremstilling af taxaner med en furyl- eller thienylsubstitueret sidekæde
ATE195421T1 (de) * 1993-03-22 2000-09-15 Univ Florida State Taxane mit amino-substituierter seitenkette
US5475011A (en) * 1993-03-26 1995-12-12 The Research Foundation Of State University Of New York Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment
WO1996013495A1 (en) * 1994-10-28 1996-05-09 The Research Foundation Of State University Of New York Taxoid derivatives, their preparation and their use as antitumor agents
US6100411A (en) * 1994-10-28 2000-08-08 The Research Foundation Of State University Of New York Taxoid anti-tumor agents and pharmaceutical compositions thereof
EP0914116B1 (en) * 1996-05-22 2000-10-11 Protarga Inc. Compositions comprising conjugates of cis-docosahexaenoic acid and taxotere
US5795909A (en) * 1996-05-22 1998-08-18 Neuromedica, Inc. DHA-pharmaceutical agent conjugates of taxanes
JP2003026673A (ja) * 1999-03-05 2003-01-29 Asahi Kasei Corp 骨形成促進剤

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6268381B1 (en) * 1997-12-19 2001-07-31 Kabushiki Kaisha Yakult Honsha Taxane derivatives

Also Published As

Publication number Publication date
DE60138853D1 (de) 2009-07-16
BG105965A (en) 2002-07-31
GEP20043323B (en) 2004-02-10
BR0104354A (pt) 2002-01-02
PL351380A1 (en) 2003-04-07
RO121270B1 (ro) 2007-02-28
NO20014754D0 (no) 2001-10-01
ATE432928T1 (de) 2009-06-15
CA2368274C (en) 2009-10-13
WO2001057032A1 (en) 2001-08-09
NO327910B1 (no) 2009-10-19
NO20014754L (no) 2001-11-29
UA75039C2 (en) 2006-03-15
SK13692001A3 (sk) 2002-07-02
CZ20013430A3 (cs) 2002-04-17
EP1165553A1 (en) 2002-01-02
PL202957B1 (pl) 2009-08-31
AU3480901A (en) 2001-08-14
CA2368274A1 (en) 2001-08-09
CN1380882A (zh) 2002-11-20
ZA200108055B (en) 2003-12-01
JP2003522172A (ja) 2003-07-22
BG64889B1 (bg) 2006-08-31
IL145638A0 (en) 2002-06-30
TR200102858T1 (tr) 2002-12-23
NZ514382A (en) 2004-05-28
MXPA01009905A (es) 2003-08-20
IL145638A (en) 2011-05-31
EP1165553B1 (en) 2009-06-03
TWI299732B (en) 2008-08-11
HUP0600302A2 (en) 2006-07-28
RU2262506C2 (ru) 2005-10-20

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Legal Events

Date Code Title Description
DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 20011001

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS: THE PRIORITY DETAILS IN REGARD TO PATENT APPLICATION NUMBER 34809/01 SHOULD READ: US 60/179782

DA3 Amendments made section 104

Free format text: THE NATURE OF THE AMENDMENT IS AS SHOWN IN THE STATEMENT(S) FILED 20020322