NO327233B1 - Anvendelse av en glukokortikoidreseptorantagonist for fremstilling av et medikament til forbedring av psykose hos en pasient. - Google Patents
Anvendelse av en glukokortikoidreseptorantagonist for fremstilling av et medikament til forbedring av psykose hos en pasient. Download PDFInfo
- Publication number
- NO327233B1 NO327233B1 NO20001744A NO20001744A NO327233B1 NO 327233 B1 NO327233 B1 NO 327233B1 NO 20001744 A NO20001744 A NO 20001744A NO 20001744 A NO20001744 A NO 20001744A NO 327233 B1 NO327233 B1 NO 327233B1
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- Prior art keywords
- psychosis
- psychotic
- use according
- glucocorticoid receptor
- receptor antagonist
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Classifications
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
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- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
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- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
- A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
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- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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- A—HUMAN NECESSITIES
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6097397P | 1997-10-06 | 1997-10-06 | |
| PCT/US1998/020906 WO1999017779A1 (en) | 1997-10-06 | 1998-10-05 | Methods for treating psychosis associated with glucocorticoid related dysfunction |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO20001744L NO20001744L (no) | 2000-04-05 |
| NO20001744D0 NO20001744D0 (no) | 2000-04-05 |
| NO327233B1 true NO327233B1 (no) | 2009-05-18 |
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| Application Number | Title | Priority Date | Filing Date |
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| NO20001744A NO327233B1 (no) | 1997-10-06 | 2000-04-05 | Anvendelse av en glukokortikoidreseptorantagonist for fremstilling av et medikament til forbedring av psykose hos en pasient. |
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| EP (1) | EP1023074B1 (https=) |
| JP (3) | JP2001518509A (https=) |
| KR (2) | KR100840957B1 (https=) |
| CN (3) | CN1528315A (https=) |
| AT (1) | ATE332696T1 (https=) |
| AU (1) | AU747956B2 (https=) |
| CA (1) | CA2302586C (https=) |
| CY (1) | CY1106330T1 (https=) |
| DE (1) | DE69835225T2 (https=) |
| DK (1) | DK1023074T3 (https=) |
| ES (1) | ES2268792T3 (https=) |
| IL (2) | IL135469A0 (https=) |
| NO (1) | NO327233B1 (https=) |
| NZ (1) | NZ503250A (https=) |
| PT (1) | PT1023074E (https=) |
| WO (1) | WO1999017779A1 (https=) |
Families Citing this family (35)
| Publication number | Priority date | Publication date | Assignee | Title |
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| EP0903146A1 (en) * | 1997-09-23 | 1999-03-24 | Applied Research Systems ARS Holdings N.V. | 21-Hydroy-6,19-oxidoprogesterone (210h-60p) as antiglucocorticoid |
| GB9915625D0 (en) * | 1999-07-02 | 1999-09-01 | Cortendo Ab | Method |
| US6620802B1 (en) * | 1999-11-23 | 2003-09-16 | Corcept Therapeutics, Inc. | Methods of treating mild cognitive impairment using a glucocorticoid-specific receptor antagonist |
| SI1325022T1 (sl) * | 2000-09-18 | 2007-04-30 | Applied Research Systems | Metoda za pripravo 21-hidroksi-6,19-oksidoprogesterona (21oh-6op) |
| CN1820756A (zh) * | 2001-03-23 | 2006-08-23 | 科塞普特治疗公司 | 使用糖皮质激素受体特效拮抗剂治疗压力症的方法 |
| US7163934B2 (en) | 2001-05-04 | 2007-01-16 | Corcept Therapeutics, Inc. | Methods for treating delirium glucocorticoid receptor-specific antagonists |
| DE60238671D1 (de) * | 2001-05-04 | 2011-02-03 | Corcept Therapeutics Inc | Verwendung von glucocorticoid-rezeptor-spezifischen antagonisten zur behandlung von delirium |
| AU2002319665B2 (en) | 2001-07-23 | 2006-09-21 | Corcept Therapeutics, Inc. | Methods for preventing antipsychotic-induced weight gain |
| IL160649A0 (en) * | 2001-08-31 | 2004-07-25 | Corcept Therapeutics Inc | Methods for inhibiting cognitive deterioration in adults with down syndrome |
| KR20050038580A (ko) * | 2001-10-26 | 2005-04-27 | 악조 노벨 엔.브이. | 주요 우울 장애의 치료에 사용되는(11β,17β)-11-(1,3-벤조디옥솔-5-일)-17-히드록시-17-(1-프로피닐)-에스트라-4,9-디엔-3-온의 용도 |
| WO2003043640A2 (en) * | 2001-11-23 | 2003-05-30 | Akzo Nobel N.V. | Treatment of major depressive disorder using glucocorticoid receptor antagonists |
| US7326697B2 (en) * | 2002-04-29 | 2008-02-05 | Corcept Therapeutics, Inc. | Methods for increasing the therapeutic response to electroconvulsive therapy |
| CN1665515A (zh) * | 2002-07-02 | 2005-09-07 | 科塞普特治疗公司 | 治疗与干扰素α治疗相关的精神病的方法 |
| WO2004054587A1 (en) * | 2002-12-18 | 2004-07-01 | University Of Zurich | Treatment of neuro-psychiatric disorders |
| EP1599208A4 (en) * | 2003-02-04 | 2007-09-12 | Corcept Therapeutics Inc | ANTIGLUCOCORTICOIDES FOR THE TREATMENT OF POSTPARTAL PSYCHOSIS |
| US8097606B2 (en) * | 2003-07-23 | 2012-01-17 | Corcept Therapeutics, Inc. | Antiglucocorticoids for the treatment of catatonia |
| GB0400031D0 (en) | 2004-01-03 | 2004-02-04 | Univ Sheffield | Depression treatment |
| US20090156565A1 (en) * | 2004-12-03 | 2009-06-18 | The Children's Hospital Of Philadelphia | Composition and use thereof in enhancing a therapeutic effect of an antiepileptic drug |
| CN100588393C (zh) * | 2004-12-15 | 2010-02-10 | 上海三合生物技术有限公司 | 赛米司酮类用于治疗抑郁症的用途 |
| US20060229505A1 (en) * | 2005-04-08 | 2006-10-12 | Mundt James C | Method and system for facilitating respondent identification with experiential scaling anchors to improve self-evaluation of clinical treatment efficacy |
| JP2009535430A (ja) * | 2006-05-02 | 2009-10-01 | コーセプト セラピューティクス， インコーポレイテッド | Ｉｌ−２を摂取している患者における抑うつを処置するためのグルココルチコイドレセプターｉｉアンタゴニストの使用 |
| EP1987814A1 (en) * | 2007-04-30 | 2008-11-05 | Exelgyn | Mifepristone pharmaceutical compositions and their methods of preparation |
| RU2327448C1 (ru) | 2007-05-23 | 2008-06-27 | Виктор Иванович Рощин | Средство для лечения зависимости от этилового спирта и/или от наркотиков, фармацевтическая композиция, активный ингредиент фармацевтической композиции, способ лечения зависимости от этилового спирта и/или от наркотиков для лечения психосоматических и неврологических осложнений у алкоголиков и/или наркоманов |
| CA2698172C (en) * | 2007-06-15 | 2014-02-18 | Cook, Kevin M. | Androstane and pregnane steroids with potent allosteric gaba receptor chloride ionophore modulating properties |
| EP2576582B1 (en) * | 2010-05-26 | 2019-09-18 | Corcept Therapeutics, Inc. | Treatment of muscular dystrophy |
| EP2671086B1 (en) | 2011-02-03 | 2018-04-25 | Pop Test Oncology LLC | System and method for diagnosis and treatment |
| US10500216B2 (en) | 2011-11-18 | 2019-12-10 | Corcept Therapeutics, Inc. | Optimizing mifepristone absorption |
| US8986677B2 (en) * | 2012-07-30 | 2015-03-24 | Pop Test Cortisol Llc | Therapeutic compositions and methods |
| CN107530435A (zh) * | 2015-03-02 | 2018-01-02 | 科赛普特治疗学股份有限公司 | 使用糖皮质激素受体拮抗剂和生长抑素治疗acth分泌型肿瘤 |
| US9943526B2 (en) | 2015-04-21 | 2018-04-17 | Corcept Therapeutics, Inc. | Optimizing mifepristone levels for cushing's patients |
| PH12017502099B1 (en) * | 2015-05-18 | 2023-08-30 | Corcept Therapeutics Inc | Methods for diagnosing and assessing treatment for cushing's syndrome |
| US11793448B2 (en) * | 2016-10-21 | 2023-10-24 | Citizen Watch Co., Ltd. | Detection device |
| AU2020239920A1 (en) | 2019-03-18 | 2021-11-04 | Arnold L. Newman | Method of improving insulin sensitivity |
| PH12022551430A1 (en) | 2019-12-11 | 2023-11-20 | Corcept Therapeutics Inc | Methods of treating antipsychotic-induced weight gain with miricorilant |
| WO2023033900A1 (en) | 2021-09-06 | 2023-03-09 | Slayback Pharma Llc | Pharmaceutical compositions of mifepristone |
Family Cites Families (7)
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| US4814333A (en) * | 1987-07-28 | 1989-03-21 | The Trustees Of Dartmouth College | Method for treatment of hypercortisolemic, depressed patients |
| US5348729A (en) * | 1988-11-30 | 1994-09-20 | The United States Of America As Represented By The Department Of Health And Human Services | Evaluative means for detecting inflammatory reactivity |
| FR2696934B1 (fr) * | 1992-10-20 | 1995-06-02 | Conservatoire Nal Arts Metiers | Dérivés de stéroïdes naturels 3B hydroxyles ayant des propriétés de déclenchement et de stimulation de l'immunité, composition les contenant et procédé pour les obtenir. |
| IL118974A (en) * | 1995-08-17 | 2001-09-13 | Akzo Nobel Nv | History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them |
| FR2739029B1 (fr) * | 1995-09-21 | 1997-11-21 | Roussel Uclaf | Nouvelle application therapeutique des composes antimineralo-corticoides |
| DE69737791D1 (de) * | 1996-04-09 | 2007-07-19 | Univ Edinburgh | Verwendung von 7-alpha-substituierten steroiden zur behandlung von neuropsychiatrischen erkrankungen |
| FR2757400B1 (fr) * | 1996-12-19 | 1999-12-17 | Hoechst Marion Roussel Inc | Application des composes antiglucocorticoides dans le traitement des psychoses ou des comportements addictifs |
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1998
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- 1998-10-05 DE DE69835225T patent/DE69835225T2/de not_active Expired - Lifetime
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1999
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| NZ503250A (en) | 2001-09-28 |
| PT1023074E (pt) | 2006-12-29 |
| JP2009051858A (ja) | 2009-03-12 |
| CN1187053C (zh) | 2005-02-02 |
| JP2001518509A (ja) | 2001-10-16 |
| WO1999017779A1 (en) | 1999-04-15 |
| NO20001744L (no) | 2000-04-05 |
| DE69835225D1 (de) | 2006-08-24 |
| KR20010024431A (ko) | 2001-03-26 |
| CA2302586A1 (en) | 1999-04-15 |
| AU747956B2 (en) | 2002-05-30 |
| JP5180125B2 (ja) | 2013-04-10 |
| EP1023074A1 (en) | 2000-08-02 |
| EP1023074B1 (en) | 2006-07-12 |
| CN1919199A (zh) | 2007-02-28 |
| KR100840957B1 (ko) | 2008-06-24 |
| IL135469A (en) | 2007-03-08 |
| CY1106330T1 (el) | 2011-10-12 |
| US6150349A (en) | 2000-11-21 |
| IL135469A0 (en) | 2001-05-20 |
| ATE332696T1 (de) | 2006-08-15 |
| KR100804558B1 (ko) | 2008-02-20 |
| CN1272788A (zh) | 2000-11-08 |
| US6362173B1 (en) | 2002-03-26 |
| DK1023074T3 (da) | 2006-11-06 |
| CA2302586C (en) | 2008-06-10 |
| DE69835225T2 (de) | 2007-07-05 |
| JP2009132743A (ja) | 2009-06-18 |
| KR20070032822A (ko) | 2007-03-22 |
| ES2268792T3 (es) | 2007-03-16 |
| AU9683298A (en) | 1999-04-27 |
| NO20001744D0 (no) | 2000-04-05 |
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